المؤلفون: Jason Deng, Svetlana Belyanskaya, Ninad Prabhu, Christopher Arico-Muendel, Hongfeng Deng, Christopher B. Phelps, David I. Israel, Hongfang Yang, Joseph Boyer, G. Joseph Franklin, Jeremy L. Yap, Kenneth E. Lind, Ching-Hsuan Tsai, Christine Donahue, Jennifer D. Summerfield

المصدر: SLAS Discovery, Vol 29, Iss 5, Pp 100171- (2024)

مصطلحات موضوعية: DNA encoded library technology, Affinity selection, Cell profiling, Proteomics, Biomarker, Theranostics, Medicine (General), R5-920, Biotechnology, TP248.13-248.65

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2472555224000339; https://doaj.org/toc/2472-5552

URL الوصول: https://doaj.org/article/200cb0758edc446ea0423cf022c88bf1

المؤلفون: Laura Guasch, Michael Reutlinger, Daniel Stoffler, Moreno Wichert

المصدر: CHIMIA, Vol 75, Iss 1-2 (2021)

مصطلحات موضوعية: Affinity-based selections/compound screening, Combinatorial chemistry, Dna-encoded library technology (delt), Machine learning, Neural networks, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.chimia.ch/chimia/article/view/1168; https://doaj.org/toc/0009-4293; https://doaj.org/toc/2673-2424

URL الوصول: https://doaj.org/article/30f68c06a25047d0ad11169e31c69a5b

المؤلفون: Francesco Rianjongdee (9260972), Stephen J. Atkinson (1297362), Chun-wa Chung (1343454), Paola Grandi (1343472), James R. J. Gray (9105255), Laura J. Kaushansky (11112770), Patricia Medeiros (8232798), Cassie Messenger (8189169), Alex Phillipou (8551068), Alex Preston (9105252), Rab K. Prinjha (449759), Inmaculada Rioja (8539), Alexander L. Satz (1507594), Simon Taylor (441637), Ian D. Wall (2525425), Robert J. Watson (1343463), Gang Yao (31248), Emmanuel H. Demont (1399288)

مصطلحات موضوعية: Biochemistry, Medicine, Genetics, Pharmacology, Immunology, Cancer, Infectious Diseases, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, selectivity, structure-based drug design, novel BET BD 2-selective chemotype, DNA-encoded library technologies, Selective BET BD 2 Inhibitor, DNA-Encoded Library Technology Scre., bromodomain, novel chemical probe, physicochemical properties, BET BD 2-inhibitor, ABBV, GSK

Relation: https://figshare.com/articles/journal_contribution/Discovery_of_a_Highly_Selective_BET_BD2_Inhibitor_from_a_DNA-Encoded_Library_Technology_Screening_Hit/14959178

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00412.s002

المؤلفون: Ghotas Evindar, Zhengrong Zhu, Yun Ding, Kenneth E Lind, Christopher P. Davie, LaShadric C. Grady, Christopher B. Phelps

المصدر: Slas Discovery

مصطلحات موضوعية: 0301 basic medicine, irreversible inhibitors, 01 natural sciences, Biochemistry, Chromatography, Affinity, Analytical Chemistry, 03 medical and health sciences, Viral Proteins, Drug Discovery, Humans, selection of covalent binders, A-DNA, 3c protease, Gene Library, Original Research, 010405 organic chemistry, Drug discovery, Chemistry, affinity selections, DEL, Rupintrivir, 3C Viral Proteases, Combinatorial chemistry, Microspheres, DNA-encoded chemical libraries, 0104 chemical sciences, Cysteine Endopeptidases, 030104 developmental biology, Covalent bond, Molecular Medicine, covalent inhibitors, Selection method, DNA-encoded library technology, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ba1000b9d708cbbb3d1ab97b3fa5899
https://pubmed.ncbi.nlm.nih.gov/30383465