المؤلفون: Mina, John G., Parthasarathy, Anutthaman, Porta, Exequiel O., Denny, Paul W., Kalesh, Karunakaran

المصدر: Mina , J G , Parthasarathy , A , Porta , E O , Denny , P W & Kalesh , K 2024 , ' BONCAT-iTRAQ Labelling Reveals Molecular Markers of Adaptive Responses in Toxoplasma gondii to Pyrimethamine Treatment. ' , Pathogens , vol. 13 , no. 10 , 879 . https://doi.org/10.3390/pathogens13100879

وصف الملف: application/pdf

الاتاحة: https://research.tees.ac.uk/en/publications/7bae4f0a-457a-4825-be3b-4271c357abd2
https://doi.org/10.3390/pathogens13100879
https://research.tees.ac.uk/ws/files/89605471/pathogens-13-00879.pdf

المؤلفون: Alpizar-Sosa, Edubiel A, Zimbres, Flavia M, Mantilla, Brian S, Dickie, Emily A, Wei, Wenbin, Burle-Caldas, Gabriela A, Filipe, Laura N S, Van Bocxlaer, Katrien, Price, Helen P, Ibarra-Meneses, Ana V, Beaudry, Francis, Fernandez-Prada, Christopher, Whitfield, Philip D, Barrett, Michael P, Denny, Paul W

وصف الملف: text

Relation: https://eprints.whiterose.ac.uk/215875/1/alpizar-sosa-et-al-2024-evaluation-of-the-leishmania-inositol-phosphorylceramide-synthase-as-a-drug-target-using-a.pdf; Alpizar-Sosa, Edubiel A, Zimbres, Flavia M, Mantilla, Brian S et al. (12 more authors) (2024) Evaluation of the Leishmania Inositol Phosphorylceramide Synthase as a Drug Target Using a Chemical and Genetic Approach. ACS Infectious Diseases. ISSN 2373-8227

الاتاحة: https://eprints.whiterose.ac.uk/215875/
https://doi.org/10.1021/acsinfecdis.4c00284

المؤلفون: Anderson, Orlagh, Beckett, Joseph, Briggs, Carla C., Natrass, Liam A., Cranston, Charles F., Wilkinson, Elizabeth J., Owen, Jack H., Williams, Rhodri Mir, Loukaidis, Angelos, Bouillon, Marc E., Pritchard, Deiniol, Lahmann, Martina, Baird, Mark S., Denny, Paul W.

المصدر: RSC MEDICINAL CHEMISTRY. 11(7):833-842

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-305690
https://doi.org/10.1039/d0md00123f

المؤلفون: Dos Santos, Nailma S.A., Estevez-Castro, Carlos F., Macedo, Juan P., Chame, Daniela F., Castro-Gomes, Thiago, Santos-Cardoso, Mariana, Burle-Caldas, Gabriela A., Covington, Courtney N., Steel, Patrick G., Smith, Terry K., Denny, Paul W., Teixeira, Santuza M.R.

المصدر: Dos Santos , N S A , Estevez-Castro , C F , Macedo , J P , Chame , D F , Castro-Gomes , T , Santos-Cardoso , M , Burle-Caldas , G A , Covington , C N , Steel , P G , Smith , T K , Denny , P W & Teixeira , S M R 2023 , ' Disruption of the inositol phosphorylceramide synthase gene affects Trypanosoma cruzi differentiation and infection capacity ' , PLoS Neglected Tropical Diseases , vol. 17 , no. 9 , e0011646 . https://doi.org/10.1371/journal.pntd.0011646

وصف الملف: application/pdf

الاتاحة: https://research-portal.st-andrews.ac.uk/en/publications/a4f60450-f08e-48d0-8ee5-41df16add7b5
https://doi.org/10.1371/journal.pntd.0011646
https://research-repository.st-andrews.ac.uk/bitstream/10023/29280/1/Dos-Santos_2023_PLoSNTD_Disruption-inositol_CC.pdf
http://www.scopus.com/inward/record.url?scp=85173589534&partnerID=8YFLogxK

المؤلفون: Porta, Exequiel O., Gao, Liqian, Denny, Paul W., Steel, Patrick G., Kalesh, Karunakaran

المصدر: Porta , E O , Gao , L , Denny , P W , Steel , P G & Kalesh , K 2023 , ' Inhibition of HSP90 distinctively modulates the global phosphoproteome of Leishmania mexicana developmental stages. ' , Microbiology spectrum , vol. 11 , no. 6 , e0296023 . https://doi.org/10.1128/spectrum.02960-23

Relation: https://research.tees.ac.uk/en/publications/24a40353-564c-4935-aa5a-2fb5dc819dd8

الاتاحة: https://research.tees.ac.uk/en/publications/24a40353-564c-4935-aa5a-2fb5dc819dd8
https://doi.org/10.1128/spectrum.02960-23
https://journals.asm.org/doi/10.1128/spectrum.02960-23

المؤلفون: Elsheikha, Hany M., Al-Sandaqchi, Alaa T., Harun, Mohammad S.R., Winterton, Francesca, Altharawi, Ali, Elsaied, Nashwa A., Stevenson, Carl W., MacNaughtan, William, Mina, John G.M., Denny, Paul W., Cinque, Gianfelice, Chan, Ka Lung Andrew

مصطلحات موضوعية: General Medicine

Relation: https://nottingham-repository.worktribe.com/output/7537723; Cells; Volume 11; Issue 5

الاتاحة: https://doi.org/10.3390/cells11050811
https://nottingham-repository.worktribe.com/file/7537723/1/Elsheikha%20Et%20Al%202022
https://nottingham-repository.worktribe.com/output/7537723

المؤلفون: Alpizar-Sosa, Edubiel A., Binti Ithnin, Nur Raihana, Wei, Wenbin, Pountain, Andrew W., Weidt, Stefan K., Donachie, Anne M., Ritchie, Ryan, Dickie, Emily A., Burchmore, Richard J.S., Denny, Paul W., Barrett, Michael P.

وصف الملف: text

Relation: https://eprints.gla.ac.uk/282174/1/282174.pdf; Alpizar-Sosa, E. A. et al. (2022) Amphotericin B resistance in Leishmania mexicana: Alterations to sterol metabolism and oxidative stress response. PLoS Neglected Tropical Diseases , 16(9), e0010779. (doi:10.1371/journal.pntd.0010779 ) (PMID:36170238) (PMCID:PMC9581426)

الاتاحة: https://eprints.gla.ac.uk/282174/
https://eprints.gla.ac.uk/282174/1/282174.pdf

المؤلفون: Alpizar-Sosa, Edubiel A., Kumordzi, Yasmine, Wei, Wenbin, Whitfield, Phillip D., Barrett, Michael P., Denny, Paul W.

وصف الملف: text

Relation: https://eprints.gla.ac.uk/281965/1/281965.pdf; Alpizar-Sosa, E. A., Kumordzi, Y., Wei, W., Whitfield, P. D. , Barrett, M. P. and Denny, P. W. (2022) Genome deletions to overcome the directed loss of gene function in Leishmania. Frontiers in Cellular and Infection Microbiology , 12, 988688. (doi:10.3389/fcimb.2022.988688 ) (PMID:36211960) (PMCID:PMC9539739)

الاتاحة: https://eprints.gla.ac.uk/281965/
https://eprints.gla.ac.uk/281965/1/281965.pdf

المؤلفون: Kalesh, Karunakaran, Wei, Wenbin, Mantilla, Brian S., Roumeliotis, Theodoros I., Choudhary, Jyoti, Denny, Paul W.

المساهمون: Downing, Tim, UKRI | Medical Research Council, Cancer Research UK

المصدر: Microbiology Spectrum ; volume 10, issue 1 ; ISSN 2165-0497

الاتاحة: http://dx.doi.org/10.1128/spectrum.02422-21
https://journals.asm.org/doi/pdf/10.1128/spectrum.02422-21

المؤلفون: Mina, John G.M., Charlton, Rebecca L., Alpizar-Sosa, Edubiel, Escrivani, Douglas O., Brown, Christopher, Alqaisi, Amjed, Borsodi, Maria Paula G., Figueiredo, Claudia P., De Lima, Emanuelle V., Dickie, Emily A., Wei, Wenbin, Coutinho-Silva, Robson, Merritt, Andy, Smith, Terry K., Barrett, Michael P., Rossi-Bergmann, Bartira, Denny, Paul W., Steel, Patrick G.

المصدر: Mina , J G M , Charlton , R L , Alpizar-Sosa , E , Escrivani , D O , Brown , C , Alqaisi , A , Borsodi , M P G , Figueiredo , C P , De Lima , E V , Dickie , E A , Wei , W , Coutinho-Silva , R , Merritt , A , Smith , T K , Barrett , M P , Rossi-Bergmann , B , Denny , P W & Steel , P G 2021 , ' Antileishmanial chemotherapy through clemastine fumarate mediated inhibition of the Leishmania inositol ....

مصطلحات موضوعية: Ceramide, Clemastine fumarate, IPCS, Leishmania, Repurposing, Sphingolipids

وصف الملف: application/pdf

الاتاحة: https://risweb.st-andrews.ac.uk/portal/en/researchoutput/antileishmanial-chemotherapy-through-clemastine-fumarate-mediated-inhibition-of-the-leishmania-inositol-phosphorylceramide-synthase(e1e57090-5c96-4a96-9b15-7a44fcc18e9c).html
https://doi.org/10.1021/acsinfecdis.0c00546
https://research-repository.st-andrews.ac.uk/bitstream/10023/21321/1/Mina_2020_ACSID_Antileishmanial_CC.pdf

المؤلفون: Escrivani, Douglas O., Charlton, Rebecca L., Caruso, Marjolly B., Burle-Caldas, Gabriela A., Borsodi, Maria Paula G., Zingali, Russolina B., Arruda-Costa, Natalia, Palmeira-Mello, Marcos V., de Jesus, Jéssica B., Souza, Alessandra M. T., Abrahim-Vieira, Bárbara, Freitag-Pohl, Stefanie, Pohl, Ehmke, Denny, Paul W., Rossi-Bergmann, Bartira, Steel, Patrick G.

المصدر: PLOS Neglected Tropical Diseases, 2021, Vol.15(11), pp.e0009951 [Peer Reviewed Journal]

وصف الملف: application/pdf

Relation: dro:35099; http://dro.dur.ac.uk/35099/; https://doi.org/10.1371/journal.pntd.0009951; http://dro.dur.ac.uk/35099/1/35099.pdf

الاتاحة: http://dro.dur.ac.uk/35099/
http://dro.dur.ac.uk/35099/1/35099.pdf
https://doi.org/10.1371/journal.pntd.0009951

المؤلفون: Kalesh, Karunakaran, Sundriyal, Sandeep, Perera, Hirunika, Cobb, Steven L., Denny, Paul W.

المصدر: mSystems, 2021 [Peer Reviewed Journal]

وصف الملف: application/pdf

Relation: dro:33024; http://dro.dur.ac.uk/33024/; https://msystems.asm.org/content/6/3/e00089-21/article-info; http://dro.dur.ac.uk/33024/1/33024.pdf

الاتاحة: http://dro.dur.ac.uk/33024/
http://dro.dur.ac.uk/33024/1/33024.pdf
https://doi.org/10.1128/mSystems.00089-21
https://msystems.asm.org/content/6/3/e00089-21/article-info

المؤلفون: Denny, Paul W, Kalesh, Karunakaran

المصدر: Denny , P W & Kalesh , K 2021 , ' How can proteomics overhaul our understanding of Leishmania biology? ' , Expert Review of Proteomics , vol. 17 , no. 11-12 , pp. 789-792 . https://doi.org/10.1080/14789450.2020.1885375

الاتاحة: https://research.tees.ac.uk/en/publications/34e18181-64a6-44cc-8d61-e45005fefe4c
https://doi.org/10.1080/14789450.2020.1885375
http://www.scopus.com/inward/record.url?eid=2-s2.0-85100979230&partnerID=MN8TOARS

المؤلفون: Mantilla, Brian S., Azevedo, Cristina, Denny, Paul W., Saiardi, Adolfo, Docampo, Roberto

المساهمون: Burleigh, Barbara, UKRI | Medical Research Council, HHS | NIH | National Institute of Allergy and Infectious Diseases, UKRI Grand Challenge Research Fund

المصدر: mBio ; volume 12, issue 6 ; ISSN 2150-7511

الاتاحة: http://dx.doi.org/10.1128/mbio.01981-21
https://journals.asm.org/doi/pdf/10.1128/mBio.01981-21

المؤلفون: Köhler, Sabine, Delwiche, Charles F., Denny, Paul W., Tilney, Lewis G., Webster, Paul, Wilson, R. J. M., Palmer, Jeffrey D., Roos, David S.

المصدر: Science, 1997 Mar 01. 275(5305), 1485-1489.

URL الوصول: https://www.jstor.org/stable/2892282

المؤلفون: Faridnia, Roghiyeh, Kalani, Hamed, Hezarjaribi, Hajar Ziaei, Denny, Paul W., Rafie, Alireza, Fakhar, Mahdi, Virgilio, Stela

المصدر: Microbial pathogenesis, 2020, Vol.147, pp.104406 [Peer Reviewed Journal]

وصف الملف: application/pdf

Relation: dro:31454; http://dro.dur.ac.uk/31454/; https://doi.org/10.1016/j.micpath.2020.104406; http://dro.dur.ac.uk/31454/1/31454.pdf

الاتاحة: http://dro.dur.ac.uk/31454/
http://dro.dur.ac.uk/31454/1/31454.pdf
https://doi.org/10.1016/j.micpath.2020.104406

المؤلفون: Karunakaran, Kalesh, Denny, Paul W.

المصدر: PLoS neglected tropical diseases, 2019, Vol.13(12), pp.e0007651 [Peer Reviewed Journal]

وصف الملف: application/pdf

Relation: dro:29948; http://dro.dur.ac.uk/29948/; https://doi.org/10.1371/journal.pntd.0007651; http://dro.dur.ac.uk/29948/1/29948.pdf

الاتاحة: http://dro.dur.ac.uk/29948/
http://dro.dur.ac.uk/29948/1/29948.pdf
https://doi.org/10.1371/journal.pntd.0007651

المؤلفون: Britt, Hannah M., García-Herrero, Clara A., Denny, Paul W., Mosely, Jackie A., Sanderson, John M.

المصدر: Chemical science, 2019, Vol.10(3), pp.674-680 [Peer Reviewed Journal]

وصف الملف: application/pdf

Relation: dro:27050; http://dro.dur.ac.uk/27050/; https://doi.org/10.1039/c8sc04831b; http://dro.dur.ac.uk/27050/1/27050.pdf; http://dro.dur.ac.uk/27050/2/27050.pdf

الاتاحة: http://dro.dur.ac.uk/27050/
http://dro.dur.ac.uk/27050/1/27050.pdf
http://dro.dur.ac.uk/27050/2/27050.pdf
https://doi.org/10.1039/c8sc04831b

المؤلفون: Pinneh, Elizabeth C., Mina, John G., Stark, Michael J. R., Lindell, Stephen D., Luemmen, Peter, Knight, Marc R., Steel, Patrick G., Denny, Paul W.

المصدر: Pinneh , E C , Mina , J G , Stark , M J R , Lindell , S D , Luemmen , P , Knight , M R , Steel , P G & Denny , P W 2019 , ' The identification of small molecule inhibitors of the plant inositol phosphorylceramide synthase which demonstrate herbicidal activity ' , Scientific Reports , vol. 9 , 8083 , pp. 1-8 . https://doi.org/10.1038/s41598-019-44544-1

مصطلحات موضوعية: /dk/atira/pure/subjectarea/asjc/1000, name=General

وصف الملف: application/pdf

Relation: https://discovery.dundee.ac.uk/en/publications/199e37b7-ffe2-4677-9794-249bf9e729db

الاتاحة: https://discovery.dundee.ac.uk/en/publications/199e37b7-ffe2-4677-9794-249bf9e729db
https://doi.org/10.1038/s41598-019-44544-1
https://discovery.dundee.ac.uk/ws/files/34464902/s41598_019_44544_1.pdf
http://www.scopus.com/inward/record.url?scp=85066487185&partnerID=8YFLogxK

المؤلفون: Pinneh, Elizabeth C., Stoppel, Rhea, Knight, Heather, Knight, Marc R., Steel, Patrick G., Denny, Paul W.

المساهمون: Wu, Keqiang, Biotechnology and Biological Sciences Research Council

المصدر: PLOS ONE ; volume 14, issue 5, page e0217087 ; ISSN 1932-6203

الاتاحة: http://dx.doi.org/10.1371/journal.pone.0217087
http://dx.plos.org/10.1371/journal.pone.0217087