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المؤلفون: Devon R. Blake, Emanuel F. Petricoin, Thomas S. K. Gilbert, Zane D. Kaiser, Priya S. Hibshman, Elisa Baldelli, Adrienne D. Cox, Channing J. Der, Runying Yang, Lee M. Graves, Jennifer E. Klomp, J. Nathaniel Diehl, Kayla R. Snare, Laura E. Herring, Mariaelena Pierobon, Richard G. Hodge, Naim U. Rashid, Björn Papke
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: MAPK/ERK pathway, extracellular signal–regulated kinase, mitogen-activated protein kinase, endocrine system diseases, STAT3, signal transducer and activator of transcription 3, PDAC, pancreatic ductal adenocarcinoma, pancreatic cancer, Cell Cycle Proteins, SHP2, SH2 domain–containing phosphatase-2, ERK, extracellular signal–regulated kinase, medicine.disease_cause, Biochemistry, Receptor tyrosine kinase, DDR1, Kinome, AM, acetoxymethyl, cancer biology, biology, Kinase, MEKi, MEK inhibitor, MEK inhibitor, kinome, Protein-Tyrosine Kinases, PLK1, polo-like kinase 1, Wee1, Mitogen-activated protein kinase, KRAS, RTK, receptor tyrosine kinase, JAK, Janus kinase, Carcinoma, Pancreatic Ductal, Research Article, MAP Kinase Signaling System, mTOR, mammalian target of rapamycin, MEK, mitogen-activated protein kinase/ERK kinase, MIB, multiplexed inhibitor bead, Proto-Oncogene Proteins p21(ras), PI, propidium iodide, cDNA, complementary DNA, proteomics, ERKi, ERK inhibitor, NCI, National Cancer Institute, SOS1, SOS Ras/Rac guanine nucleotide exchange factor 1, Cell Line, Tumor, medicine, Humans, WEE1, Molecular Biology, RPPA, reverse phase protein array, TBST, TBS with 0.05% Tween-20, LFQ, label-free quantification, Cell Biology, digestive system diseases, EGFR, epidermal growth factor receptor, Pancreatic Neoplasms, Mutation, biology.protein, Cancer research, RAS protein, MAPK, mitogen-activated protein kinase, DDR1, discoidin domain receptor 1
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المصدر: Matrix Biology Plus, Vol 6, Iss, Pp 100038-(2020)
Matrix Biology Plusمصطلحات موضوعية: HA, hyaluronan, Computer science, Biochemistry, miR, microRNA, tPA, tissue-type plasminogen activator, Matrix (mathematics), Human disease, TGFβ, transforming growth factor β, PG, proteoglycans, lcsh:QH301-705.5, Cancer, Cognitive science, Complex matrix, MET, mesenchymal-epithelial transition, uPA, urokinase-type plasminogen activator, LEKTI, lympho-epithelial Kazal-type inhibitor, EMILIN2, elastin microfibril interfacer 2, VEGF, vascular endothelial growth factor, Phenotype, Reciprocity (evolution), ECM, extracellular matrix, UVR, ultraviolet radiation, ERβ, estrogen receptor β, PLL, poly-l-lysine, SLRP, small leucine rich proteoglycans, Research strategies, MMP, matrix metalloproteinases, SSR, solar-simulated radiation, ADAM, a disintegrin and metalloproteinases, Proteoglycans, AGE, advanced glycation end products, Collagen, Methodologies, RTK, receptor tyrosine kinase, EMT, epithelial-mesenchymal transition, HAS2-AS1, HAS2 antisense 1, LOX, lysyl oxidases, Histology, EMILIN1, elastin microfibril interfacer 1, LTBP, latent TGFβ-binding proteins, Biophysics, Original research, Article, IR-A, insulin receptor A, OB, osteoblast, ROS, reactive oxygen species, IBC, inflammatory breast cancer, Genetics, IGF-IR, insulin growth factor I receptor, HAS2, hyaluronan synthase 2, PARs, protease activated receptors, Molecular Biology, EGF, epidermal growth factor, HMGA2, high-mobility group AT-Hook 2, HB-EGF, heparin binding EGF, MAGP, microfibril-associated glycoproteins, ERα, estrogen receptor α, Cell Biology, Human body, EGFR, epidermal growth factor receptor, OI, osteogenesis imperfecta, lcsh:Biology (General), TNT, tunneling nanotubes, GBM, glioblastoma, Angiogenesis, DDR1, discoidin domain receptor 1