المؤلفون: Sarah E. Woodfield, Yan Shi, Roma H. Patel, Zhenghu Chen, Aayushi P. Shah, Richard S. Whitlock, Aryana M. Ibarra, Samuel R. Larson, Stephen F. Sarabia, Andrew Badachhape, Zbigniew Starosolski, Ketan B. Ghaghada, Pavel Sumazin, D. Allen Annis, Dolores López-Terrada, Sanjeev A. Vasudevan

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/2c835b5e701047a99457ad48818f16a6

المؤلفون: Samuel Y. Ng, Noriaki Yoshida, Amanda L. Christie, Mahmoud Ghandi, Neekesh V. Dharia, Joshua Dempster, Mark Murakami, Kay Shigemori, Sara N. Morrow, Alexandria Van Scoyk, Nicolas A. Cordero, Kristen E. Stevenson, Maneka Puligandla, Brian Haas, Christopher Lo, Robin Meyers, Galen Gao, Andrew Cherniack, Abner Louissaint, Valentina Nardi, Aaron R. Thorner, Henry Long, Xintao Qiu, Elizabeth A. Morgan, David M. Dorfman, Danilo Fiore, Julie Jang, Alan L. Epstein, Ahmet Dogan, Yanming Zhang, Steven M. Horwitz, Eric D. Jacobsen, Solimar Santiago, Jian-Guo Ren, Vincent Guerlavais, D. Allen Annis, Manuel Aivado, Mansoor N. Saleh, Amitkumar Mehta, Aviad Tsherniak, David Root, Francisca Vazquez, William C. Hahn, Giorgio Inghirami, Jon C. Aster, David M. Weinstock, Raphael Koch

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/ecc83cf960564bd2938fc055d45d8a01

المؤلفون: Sarah E. Woodfield, Yan Shi, Roma H. Patel, Zhenghu Chen, Aayushi P. Shah, Rohit K. Srivastava, Richard S. Whitlock, Aryana M. Ibarra, Samuel R. Larson, Stephen F. Sarabia, Andrew Badachhape, Zbigniew Starosolski, Ketan B. Ghaghada, Pavel Sumazin, D. Allen Annis, Dolores López-Terrada, Sanjeev A. Vasudevan

المصدر: Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2045-2322

URL الوصول: https://doaj.org/article/4d0f9217fca3401482d0f49ebd128ace

المؤلفون: Galina Selivanova, John Inge Johnsen, D. Allen Annis, Lisa S. Westerberg, Mariana M.S. Oliveira, Yue Zhan, Manuel Aivado, Luis A. Carvajal, Vincent Guerlavais, Gema Sanz Santos, Madhurendra Singh, Xiaolei Zhou

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d0ed448aac60a4538b62cc059238edd
https://doi.org/10.1158/2159-8290.22540232.v1

المؤلفون: Galina Selivanova, John Inge Johnsen, D. Allen Annis, Lisa S. Westerberg, Mariana M.S. Oliveira, Yue Zhan, Manuel Aivado, Luis A. Carvajal, Vincent Guerlavais, Gema Sanz Santos, Madhurendra Singh, Xiaolei Zhou

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31d0a367b500ee66238ecfeec7d5f38e
https://doi.org/10.1158/2159-8290.22540229

المؤلفون: Galina Selivanova, John Inge Johnsen, D. Allen Annis, Lisa S. Westerberg, Mariana M.S. Oliveira, Yue Zhan, Manuel Aivado, Luis A. Carvajal, Vincent Guerlavais, Gema Sanz Santos, Madhurendra Singh, Xiaolei Zhou

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a1fef0ce4d0fafc94719ed54d6cf50f
https://doi.org/10.1158/2159-8290.c.6549320.v1

المؤلفون: Galina Selivanova, John Inge Johnsen, D. Allen Annis, Lisa S. Westerberg, Mariana M.S. Oliveira, Yue Zhan, Manuel Aivado, Luis A. Carvajal, Vincent Guerlavais, Gema Sanz Santos, Madhurendra Singh, Xiaolei Zhou

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ae2c07cecd38648234ebea4a587fe19
https://doi.org/10.1158/2159-8290.22540238

المؤلفون: D. Allen Annis, Peter J. Dandliker, Didier M. Roche, Jean-Yves Ortholand, Renaud Prudent

المصدر: Nature Reviews Chemistry. 5:62-71

مصطلحات موضوعية: Computer science, Drug discovery, General Chemical Engineering, Ligand binding assay, General Chemistry, Computational biology, Binding site, Protein degradation, Mass spectrometry, Chemical space

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4ac65b0bcb8b411f753f2a97a977a548
https://doi.org/10.1038/s41570-020-00229-2

المؤلفون: Mansoor N. Saleh, Manish R. Patel, Todd M. Bauer, Sanjay Goel, Gerald S. Falchook, Geoffrey I. Shapiro, Ki Y. Chung, Jeffrey R. Infante, Robert M. Conry, Guilherme Rabinowits, David S. Hong, Judy S. Wang, Ulrich Steidl, Loren D. Walensky, Gurudatta Naik, Vincent Guerlavais, Vojislav Vukovic, D. Allen Annis, Manuel Aivado, Funda Meric-Bernstam

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research. 27(19)

مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, Lymphoma, Maximum Tolerated Dose, Anemia, Antineoplastic Agents, Neutropenia, Gastroenterology, Mice, Pharmacokinetics, Internal medicine, Neoplasms, Medicine, Animals, Humans, Adverse effect, Fatigue, Dose-Response Relationship, Drug, business.industry, Proto-Oncogene Proteins c-mdm2, medicine.disease, Oncology, Apoptosis, Pharmacodynamics, Biomarker (medicine), Alkaline phosphatase, Tumor Suppressor Protein p53, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbbe63ad5994923a7c864f392c3bf857
https://pubmed.ncbi.nlm.nih.gov/35045962

المؤلفون: Joshua M. Dempster, D. Allen Annis, Neekesh V. Dharia, William C. Hahn, Xintao Qiu, Brian J. Haas, Julie Jang, Kay Shigemori, Giorgio Inghirami, Ahmet Dogan, Sara N. Morrow, Eric D. Jacobsen, Andrew D. Cherniack, Aviad Tsherniak, Jian-Guo Ren, Noriaki Yoshida, Mark A. Murakami, Aaron R. Thorner, David M. Weinstock, Manuel Aivado, Amanda L. Christie, Nicolas A. Cordero, Vincent Guerlavais, Abner Louissaint, Robin M. Meyers, Raphael Koch, Alan L. Epstein, Yanming Zhang, Maneka Puligandla, Mahmoud Ghandi, David E. Root, Elizabeth A. Morgan, Mansoor N. Saleh, Samuel Y. Ng, Danilo Fiore, Jon C. Aster, Alexandria Van Scoyk, Valentina Nardi, Henry W. Long, David M. Dorfman, Amitkumar Mehta, Steven M. Horwitz, Solimar Santiago, Kristen E. Stevenson, Francisca Vazquez, Galen F. Gao, Christopher Lo

المساهمون: Ng, S. Y., Yoshida, N., Christie, A. L., Ghandi, M., Dharia, N. V., Dempster, J., Murakami, M., Shigemori, K., Morrow, S. N., Van Scoyk, A., Cordero, N. A., Stevenson, K. E., Puligandla, M., Haas, B., Lo, C., Meyers, R., Gao, G., Cherniack, A., Louissaint, A., Nardi, V., Thorner, A. R., Long, H., Qiu, X., Morgan, E. A., Dorfman, D. M., Fiore, D., Jang, J., Epstein, A. L., Dogan, A., Zhang, Y., Horwitz, S. M., Jacobsen, E. D., Santiago, S., Ren, J. -G., Guerlavais, V., Annis, D. A., Aivado, M., Saleh, M. N., Mehta, A., Tsherniak, A., Root, D., Vazquez, F., Hahn, W. C., Inghirami, G., Aster, J. C., Weinstock, D. M., Koch, R.

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Myeloid, MDMX, Cell, Drug Evaluation, Preclinical, General Physics and Astronomy, Cell Cycle Proteins, Whole Exome Sequencing, Romidepsin, Antineoplastic Agent, Mice, Depsipeptides, Cell Cycle Protein, Imidazoline, Medicine, lcsh:Science, Depsipeptide, Nuclear Protein, Proto-Oncogene Protein, Multidisciplinary, biology, Remission Induction, Nuclear Proteins, Proto-Oncogene Proteins c-mdm2, 3. Good health, Gene Expression Regulation, Neoplastic, Lymphoma, Extranodal NK-T-Cell, medicine.anatomical_structure, Peptide, Mdm2, Human, medicine.drug, Protein Binding, Signal Transduction, Xenograft Model Antitumor Assay, Science, Antineoplastic Agents, Lymphoma, T-Cell, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Ikaros Transcription Factor, In vivo, Proto-Oncogene Proteins, Exome Sequencing, Animals, Humans, Imidazolines, Animal, business.industry, Complete remission, General Chemistry, Janus Kinase 2, medicine.disease, Xenograft Model Antitumor Assays, Lymphoma, 030104 developmental biology, biology.protein, Cancer research, lcsh:Q, Tumor Suppressor Protein p53, business, Peptides

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f547fda85fead85c157861340e629f0
https://doaj.org/article/ecc83cf960564bd2938fc055d45d8a01

المؤلفون: Mansoor N, Saleh, Manish R, Patel, Todd M, Bauer, Sanjay, Goel, Gerald S, Falchook, Geoffrey I, Shapiro, Ki Y, Chung, Jeffrey R, Infante, Robert M, Conry, Guilherme, Rabinowits, David S, Hong, Judy S, Wang, Ulrich, Steidl, Loren D, Walensky, Gurudatta, Naik, Vincent, Guerlavais, Vojislav, Vukovic, D Allen, Annis, Manuel, Aivado, Funda, Meric-Bernstam

المصدر: Clinical Cancer Research. 28:429-429

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::190e87a46a24a131c3ec1ad1cb942f3b
https://doi.org/10.1158/1078-0432.ccr-21-4241

المؤلفون: Vojislav Vukovic, Manuel Aivado, Dean Pavlick, Lee A. Albacker, Garrett M. Frampton, D. Allen Annis

المصدر: Journal of Clinical Oncology. 39:3124-3124

مصطلحات موضوعية: Cancer Research, P53 pathway, business.industry, Cancer, medicine.disease, Tp53 mutation, DNA sequencing, Large cohort, Oncology, P53 Tumor Suppressor Protein, Mutation (genetic algorithm), Cancer research, Medicine, business, Gene

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::4f49fa6057c1c79deb50011763dba4b1
https://doi.org/10.1200/jco.2021.39.15_suppl.3124

المؤلفون: Victor Thiruthuvanathan, Charles A. Kenworthy, Vincent Guerlavais, Swathi Rao Narayanagari, Manuel Aivado, Robert H. Singer, Robert A. Coleman, Tatyana Yatsenko, Daniela Ben Neriah, Amit Verma, Ulrich Steidl, Lumie Benard, Luis A. Carvajal, Adrien Senecal, Jesus Anampa, Britta Will, Justin C. Wheat, D. Allen Annis, Kelly Mitchell, Boris Bartholdy, Ioannis Mantzaris, Tihomira I. Todorova

المصدر: Science translational medicine. 10(436)

مصطلحات موضوعية: 0301 basic medicine, Adult, MDMX, Myeloid, Cell cycle checkpoint, Article, law.invention, 03 medical and health sciences, Mice, Young Adult, law, Proto-Oncogene Proteins, medicine, Animals, Humans, Clonogenic assay, Cells, Cultured, biology, Chemistry, Myeloid leukemia, Proto-Oncogene Proteins c-mdm2, General Medicine, medicine.disease, Leukemia, Disease Models, Animal, Leukemia, Myeloid, Acute, 030104 developmental biology, medicine.anatomical_structure, Mutation, Cancer research, biology.protein, Suppressor, Mdm2, Female, Tumor Suppressor Protein p53, Peptides

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dc398632b81dff239225dab301ef532
https://pubmed.ncbi.nlm.nih.gov/29643228

المؤلفون: William B. Donnellan, D. Allen Annis, David A. Sallman, Amit Verma, Marie Payton, Uma Borate, Rami S. Komrokji, Elizabeth H. Cull, Maria Margarita Corvez, Manuel Aivado, Dawn Pinchasik, Ulrich Steidl

المصدر: Blood. 132:4066-4066

مصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, Nausea, business.industry, Immunology, Cell Biology, Hematology, Biochemistry, Discontinuation, Clinical trial, Transplantation, 03 medical and health sciences, 030104 developmental biology, Internal medicine, Concomitant, medicine, Cytarabine, Dosing, medicine.symptom, Adverse effect, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::78b431f426facdc2bd56c9eb5510146e
https://doi.org/10.1182/blood-2018-99-118780

المؤلفون: Geoffrey I. Shapiro, Steven M. Horwitz, Lubomir Sokol, D. Allen Annis, Ronald L. Korn, Sunita D. Nasta, Andrei R. Shustov, Amitkumar Mehta, Funda Meric-Bernstam, Dawn Pinchasik, Murali Janakiram, Manish R. Patel, David M. Weinstock, Manuel Aivado, Marie Payton, Jasmine Zain, Sanjay Goel

المصدر: Blood. 132:1623-1623

مصطلحات موضوعية: 0301 basic medicine, Response rate (survey), medicine.medical_specialty, business.operation, business.industry, Immunology, Disease progression, Dual inhibitor, Mallinckrodt, Cell Biology, Hematology, Biochemistry, Preclinical data, Discontinuation, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, 030220 oncology & carcinogenesis, Family medicine, Relapsed refractory, Stapled peptide, Medicine, business, health care economics and organizations

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1668c3714bb2a7d8da7720ed1c51f7c7
https://doi.org/10.1182/blood-2018-99-116780

المؤلفون: Ronald Korn, Luis A. Carvajal, David Sutton, Manoj P. Samant, Lubomir Sokol, D. Allen Annis, Amitkumar Mehta, Andrei R. Shustov, Manuel Aivado, Vincent Guerlavais, Dawn Pinchasik, Narayana I. Narasimhan

المصدر: Blood. 132:5348-5348

مصطلحات موضوعية: Oncology, medicine.medical_specialty, business.operation, Immunology, Biochemistry, 03 medical and health sciences, Lymphocyte chemotaxis, 0302 clinical medicine, Internal medicine, Biopsy, Medicine, Pseudoprogression, medicine.diagnostic_test, business.industry, Surrogate endpoint, Mallinckrodt, Cell Biology, Hematology, medicine.disease, Clinical trial, B symptoms, 030220 oncology & carcinogenesis, medicine.symptom, business, 030217 neurology & neurosurgery, Progressive disease

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b2d37e6876fcae23b60c2d04fa7722d0
https://doi.org/10.1182/blood-2018-99-119489

المؤلفون: D. Allen Annis, Ronald Herbst, Catherine K. Smith, Wolfgang Seghezzi, Cheng-Chi Chuang, Gerald W. Shipps, Andrea D. Basso, Brian R. Lahue, Elliott B. Nickbarg, Kimberly Gray, David Sanden, Lev Vilenchik, Yao Ma, Hung V. Le, Payal R. Sheth

المصدر: Biochemistry. 49:8350-8358

مصطلحات موضوعية: Benzimidazole, Circular dichroism, Stereochemistry, Mutant, Kinesins, Antineoplastic Agents, Biochemistry, Mass Spectrometry, Motor domain, chemistry.chemical_compound, Humans, Atpase activity, Nucleotide, Adenosine Triphosphatases, chemistry.chemical_classification, Binding Sites, Nucleotides, Circular Dichroism, Protein Structure, Tertiary, chemistry, Benzamides, Quinazolines, Kinesin, Benzimidazoles, Uncompetitive inhibitor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b25222b0ed264d524f1b4cb950e3df2d
https://doi.org/10.1021/bi1005283

المؤلفون: Naim Nazef, Cliff C. Cheng, D. Allen Annis, Cheng-Chi Chuang, John D. McCarter, Huw M. Nash, Gerald W. Shipps, Todd Rowe, Robert J.M. Kurzeja

المصدر: Combinatorial Chemistry & High Throughput Screening. 12:760-771

مصطلحات موضوعية: High-throughput screening, Phosphatase, Pyrazole, Mass Spectrometry, Structure-Activity Relationship, chemistry.chemical_compound, Catalytic Domain, Drug Discovery, Combinatorial Chemistry Techniques, Structure–activity relationship, Enzyme Inhibitors, chemistry.chemical_classification, Molecular Structure, biology, Inositol Polyphosphate 5-Phosphatases, Organic Chemistry, Active site, Stereoisomerism, General Medicine, Ligand (biochemistry), Combinatorial chemistry, Phosphoric Monoester Hydrolases, High-Throughput Screening Assays, Computer Science Applications, Enzyme, chemistry, Biochemistry, biology.protein, Pyrazoles

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d151261fb2420ad78b5420bc1e802cd1
https://doi.org/10.2174/138620709789104870

المؤلفون: Naim Nazef, Huw M. Nash, Margaret Porter Scott, Cheng-Chi Chuang, D. Allen Annis

المصدر: Journal of the American Chemical Society. 126:15495-15503

مصطلحات موضوعية: Stereochemistry, Allosteric regulation, Protein Serine-Threonine Kinases, Ligands, Binding, Competitive, Biochemistry, Chemical synthesis, Mass Spectrometry, Catalysis, Colloid and Surface Chemistry, Affinity chromatography, Proto-Oncogene Proteins, Chemical affinity, Combinatorial Chemistry Techniques, Binding site, Serum Albumin, Chromatography, Receptor, Muscarinic M2, Binding Sites, ZAP-70 Protein-Tyrosine Kinase, Chemistry, Drug discovery, Proteins, Stereoisomerism, General Chemistry, Protein-Tyrosine Kinases, Staurosporine, Ligand (biochemistry), Affinities, Kinetics, Warfarin, Proto-Oncogene Proteins c-akt

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae9013eb78b1b8388f9493585457f69f
https://doi.org/10.1021/ja048365x

المؤلفون: D. Allen Annis, Jean Paul A. Orminati, G. R.A. Thaddupathy, Patrick J. Curran, Krishna Kalghatgi, Edward A. Wintner, Gerald W. Shipps, Huw M. Nash, William H. Lee, Kristin E. Rosner, Andrew N. Tyler, Carston R. Wagner, John Athanasopoulos, Lev Vilenchik, Jason S. Felsch

المصدر: International Journal of Mass Spectrometry. 238:77-83

مصطلحات موضوعية: biology, Ligand, Chemistry, Drug discovery, Antagonist, Biological activity, Condensed Matter Physics, Mass spectrometry, medicine.disease_cause, Small molecule, Combinatorial chemistry, Dihydrofolate reductase, biology.protein, medicine, Physical and Theoretical Chemistry, Instrumentation, Escherichia coli, Spectroscopy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ae966614540c07151bcb313c4614775a
https://doi.org/10.1016/j.ijms.2003.11.022