المؤلفون: D. Stephen Serafin, Natalie R. Harris, László Bálint, Elizabeth S. Douglas, Kathleen M. Caron

المصدر: Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/bac185d7ee0f4461bc185dc3d283cc04

المؤلفون: Matthew J Billard, David J Fitzhugh, Joel S Parker, Jaime M Brozowski, Marcus W McGinnis, Roman G Timoshchenko, D Stephen Serafin, Ruth Lininger, Nancy Klauber-Demore, Gary Sahagian, Young K Truong, Maria F Sassano, Jonathan S Serody, Teresa K Tarrant

المصدر: PLoS ONE, Vol 11, Iss 4, p e0152856 (2016)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC4822790?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/1ea3e1e80d024f64a99ff02f893eaede

المؤلفون: Jaime M. Brozowski, Roman G. Timoshchenko, D. Stephen Serafin, Brittney Allyn, Jessica Koontz, Emily M. Rabjohns, Rishi R. Rampersad, Yinshi Ren, Amanda M. Eudy, Taylor F. Harris, David Abraham, Daniel Mattox, Clinton T. Rubin, Matthew J. Hilton, Janet Rubin, Nancy L. Allbritton, Matthew J. Billard, Teresa K. Tarrant

المصدر: Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-15 (2022)

مصطلحات موضوعية: Bone marrow-derived mesenchymal stem cells, Mesenchymal stem cells, G protein-coupled receptors (GPCRs), G protein-coupled receptor kinase 3 (GRK3), Sphingosine-1-phosphate (S1P), Sphingosine-1-phosphate receptor (S1PR), Medicine (General), R5-920, Biochemistry, QD415-436

Relation: https://doi.org/10.1186/s13287-022-02715-4; https://doaj.org/toc/1757-6512; https://doaj.org/article/124f702e78d146ed89416332f38c7248

الاتاحة: https://doi.org/10.1186/s13287-022-02715-4
https://doaj.org/article/124f702e78d146ed89416332f38c7248

المؤلفون: Kathleen M. Caron, Remy Bonnavion, Stefan Offermanns, Christian S. M. Helker, Kyu-Won Kim, Hyouk-Bum Kwon, Duncan I. Mackie, D. Stephen Serafin, Stefan Guenter, Taekwon Son, Didier Y.R. Stainier, Alan Le Mercier

المصدر: ACS Pharmacology & Translational Science

مصطلحات موضوعية: Pharmacology, Hemogenic endothelium, biology, Leukotriene B4, GPR182, Hematopoietic stem cell, myelopoiesis, biology.organism_classification, Embryonic stem cell, Article, Cell biology, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, definitive hematopoiesis, medicine, hematopoietic stem cell, Pharmacology (medical), G protein-coupled receptor, Myelopoiesis, Receptor, Zebrafish

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f6b59f36fc424fe418bdf3f457cc95
https://doi.org/10.1021/acsptsci.0c00020

المؤلفون: Duncan I. Mackie, D. Stephen Serafin, Natalie R Harris, Natalie R Nielsen, Kathleen M. Caron

المصدر: Trends Pharmacol Sci

مصطلحات موضوعية: 0301 basic medicine, Pharmacology, genetic structures, Calcitonin Gene-Related Peptide, musculoskeletal, neural, and ocular physiology, Computational biology, Biology, Antibodies, Monoclonal, Humanized, Toxicology, Receptor Activity-Modifying Proteins, Article, Receptors, G-Protein-Coupled, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Drug development, Calcitonin Gene-Related Peptide Receptor Antagonists, Mutation, Animals, Humans, Molecular Targeted Therapy, human activities, hormones, hormone substitutes, and hormone antagonists, 030217 neurology & neurosurgery, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::325f47029b3f404d7328fceb00b68d30
https://doi.org/10.1016/j.tips.2020.01.009

المؤلفون: D. Stephen Serafin, Nancy L. Allbritton, Christopher E. Sims, Emilie R. Mainz, Tuong T. Nguyen, Teresa K. Tarrant

المصدر: Analytical Chemistry. 88:7786-7792

مصطلحات موضوعية: 0301 basic medicine, Morpholines, Cell, Arthritis, Article, Analytical Chemistry, Arthritis, Rheumatoid, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, Insulin, Phosphorylation, RNA, Small Interfering, Receptor, Protein kinase B, Cells, Cultured, 030203 arthritis & rheumatology, Tumor Necrosis Factor-alpha, Chemistry, Electrophoresis, Capillary, Fibroblasts, medicine.disease, Synoviocytes, 030104 developmental biology, medicine.anatomical_structure, Chromones, Receptors, Tumor Necrosis Factor, Type I, Rheumatoid arthritis, Cancer research, RNA Interference, Tumor necrosis factor alpha, Single-Cell Analysis, Signal transduction, Proto-Oncogene Proteins c-akt, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f44420fd5b7af9ae850aacb2c8e72ed
https://doi.org/10.1021/acs.analchem.6b01801

المؤلفون: Denise Esserman, Brittney Allyn, Daniel E Mattox, Jaime M. Brozowski, Maria F. Sassano, D. Stephen Serafin, Roman G. Timoshchenko, David P. Siderovski, Matthew J. Billard, Young K. Truong, Teresa K. Tarrant

مصطلحات موضوعية: 0301 basic medicine, media_common.quotation_subject, Immunology, CMKLR1, Article, Cell Line, Receptors, G-Protein-Coupled, 03 medical and health sciences, Mice, 0302 clinical medicine, Rheumatic Diseases, Arrestin, Chemerin, Animals, Humans, Internalization, Molecular Biology, Protein kinase B, media_common, G protein-coupled receptor, Inflammation, Mice, Knockout, G protein-coupled receptor kinase, biology, Chemistry, Beta adrenergic receptor kinase, Macrophages, G-Protein-Coupled Receptor Kinases, beta-Arrestin 2, Immunity, Innate, Cell biology, 030104 developmental biology, biology.protein, Intercellular Signaling Peptides and Proteins, Receptors, Chemokine, Chemokines, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039d41c608327229aa8aaa666fabdda3
https://europepmc.org/articles/PMC6584946/

المؤلفون: Lee M. Graves, Robert S. Hagan, Laura E. Herring, Johnny Castillo, Pengda Liu, Ricardo J. Antonia, Albert S. Baldwin, D. Stephen Serafin

المصدر: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)

مصطلحات موضوعية: Models, Molecular, lcsh:Medicine, Kinases, mTORC1, Mechanistic Target of Rapamycin Complex 1, Protein Serine-Threonine Kinases, Mass Spectrometry, Article, Cell Line, 03 medical and health sciences, Structure-Activity Relationship, Serine, Humans, Amino Acid Sequence, Phosphorylation, lcsh:Science, Mechanistic target of rapamycin, PI3K/AKT/mTOR pathway, 030304 developmental biology, Innate immunity, 0303 health sciences, Multidisciplinary, biology, Kinase, Cell growth, Chemistry, 030302 biochemistry & molecular biology, Autophagy, lcsh:R, Regulatory-Associated Protein of mTOR, Immunity, Innate, 3. Good health, Cell biology, Enzyme Activation, biology.protein, lcsh:Q, Signal transduction, Protein Binding, Signal Transduction, Cell signalling

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ec6d18144bebb93d26c8e5ec74d7a7d
https://pubmed.ncbi.nlm.nih.gov/31530866

المؤلفون: Carina Gileadi, Jonathan M. Elkins, Meagan B. Ryan, Matthew P. Walker, Melissa V. Gammons, James M. Bennett, Timothy M. Willson, David H. Drewry, Alison D. Axtman, Oleg Fedorov, Carrow I. Wells, Rafael M. Couñago, Alex D. Rabinowitz, Michael B. Major, A.S. Santiago, William J. Zuercher, Roberta R. Ruela-de-Sousa, David M. Graham, P.H.C. Godoi, Nirav Kapadia, Opher Gileadi, F.J. Sorrell, Megan J. Agajanian, Susanne Müller, D. Stephen Serafin

المصدر: SSRN Electronic Journal.

مصطلحات موضوعية: Receptor complex, Chemistry, Wnt signaling pathway, LRP6, AAK1, Receptor-mediated endocytosis, Signal transduction, Endocytosis, Tissue homeostasis, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e191023c5fff4ab5bfc701e3b3ad8934
https://doi.org/10.2139/ssrn.3188329

المؤلفون: D. Stephen Serafin, M.W. McGinnis, Roman G. Timoshchenko, Dhavalkumar D. Patel, David P. Siderovski, Nelson J. Chao, Oded Foreman, David Lee, William Lento, Denise Esserman, Matthew J. Billard, Teresa K. Tarrant

المصدر: Journal of Leukocyte Biology. 94:1243-1251

مصطلحات موضوعية: Granulocyte migration, Receptors, CXCR4, Leukocyte migration, G-Protein-Coupled Receptor Kinase 3, MAP Kinase Signaling System, Primary Immunodeficiency Diseases, Immunology, Inflammation, Biology, Cell Development, Differentiation, & Trafficking, CXCR4, Mice, Chemokine receptor, immune system diseases, hemic and lymphatic diseases, medicine, Animals, Humans, Immunology and Allergy, Cell Line, Transformed, Mice, Knockout, Myelokathexis, G protein-coupled receptor kinase, Immunologic Deficiency Syndromes, Cell Biology, medicine.disease, biological factors, Chemokine CXCL12, Disease Models, Animal, embryonic structures, biological phenomena, cell phenomena, and immunity, Warts, medicine.symptom, WHIM syndrome, Granulocytes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b65acbf332fa359147d8271d1159212d
https://doi.org/10.1189/jlb.0213097

المؤلفون: David H. Drewry, Carrow I. Wells, David M. Graham, Susanne Müller, P.H.C. Godoi, Roberta R. Ruela-de-Sousa, Nirav Kapadia, Matthew P. Walker, Megan J. Agajanian, Alex D. Rabinowitz, Fiona J. Sorrell, Meagan B. Ryan, James M. Bennett, Opher Gileadi, Alison D. Axtman, Timothy M. Willson, Tigist Y. Tamir, Yuko Nakamichi, Rafael M. Couñago, William J. Zuercher, Jonathan M. Elkins, D. Stephen Serafin, Michael B. Major, Melissa V. Gammons, Carina Gileadi, Oleg Fedorov, A.S. Santiago

المصدر: Cell Reports

مصطلحات موضوعية: 0301 basic medicine, LRP6, Male, Receptor complex, kinase, education, Protein Serine-Threonine Kinases, Endocytosis, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, gain-of-function screen, WNT signaling, Animals, Humans, AP2M1, Protein Kinase Inhibitors, Wnt Signaling Pathway, Tissue homeostasis, AAK1, Feedback, Physiological, Chemistry, Wnt signaling pathway, Receptor-mediated endocytosis, Clathrin, Cell biology, Wnt Proteins, 030104 developmental biology, HEK293 Cells, Low Density Lipoprotein Receptor-Related Protein-6, Signal transduction, feedback loop, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f44192008f344af1af0d43292bea0628
http://europepmc.org/articles/PMC6315376

المؤلفون: David J. Fitzhugh, M.W. McGinnis, Roman G. Timoshchenko, Joel S. Parker, Jaime M. Brozowski, D. Stephen Serafin, Nancy Klauber-DeMore, Jonathan S. Serody, G. Gary Sahagian, Young K. Truong, Ruth A. Lininger, Teresa K. Tarrant, Maria F. Sassano, Matthew J. Billard

المصدر: PLoS ONE, Vol 11, Iss 4, p e0152856 (2016)
PLoS ONE

مصطلحات موضوعية: 0301 basic medicine, Oncology, Chemokine, G-Protein-Coupled Receptor Kinase 3, lcsh:Medicine, CXCR4, Biochemistry, Metastasis, Chemokine receptor, Mice, 0302 clinical medicine, Cell Signaling, Breast Tumors, Basic Cancer Research, Medicine and Health Sciences, Neoplasm Metastasis, lcsh:Science, Triple-negative breast cancer, Multidisciplinary, Chemotaxis, Animal Models, 3. Good health, Cancer Cell Migration, Cell Motility, 030220 oncology & carcinogenesis, Female, Chemokines, Research Article, Signal Transduction, medicine.medical_specialty, Transmembrane Receptors, Mouse Models, Breast Neoplasms, Cell Migration, Biology, Research and Analysis Methods, 03 medical and health sciences, Breast cancer, Model Organisms, Internal medicine, Breast Cancer, medicine, Animals, Humans, Neoplasm Invasiveness, Gene Silencing, G protein-coupled receptor, G protein-coupled receptor kinase, lcsh:R, Cancers and Neoplasms, Biology and Life Sciences, Proteins, Cell Biology, medicine.disease, G-Protein Signaling, 030104 developmental biology, Cancer research, biology.protein, lcsh:Q, G Protein Coupled Receptors, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::403efa10bd7f2f2c0dce8408ac790355
http://europepmc.org/articles/PMC4822790?pdf=render

المؤلفون: Patricia L. Lugar, Luanna Yang, Shaili N. Shah, Kristy L. Richards, Paula Scotland, D. Stephen Serafin, Roman G. Timoshchenko, Matthew J. Billard, Teresa K. Tarrant

المصدر: Journal of Allergy and Clinical Immunology. 137:AB179

مصطلحات موضوعية: Genetics, Immunology, Genetic predisposition, medicine, Immunology and Allergy, Biology, medicine.disease_cause, Autoimmunity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::059430af8187e0245375c1783c20ad2f
https://doi.org/10.1016/j.jaci.2015.12.720