المؤلفون: Fonseca Casals, Francina

المساهمون: University/Department: Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut

Thesis Advisors: Torrens, Marta, Torre Fornell, Rafael de la

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: genotip, haplotip, gen resistència multisubstància (ABCB1), gen miocardina (MYOCD), gen, gen candidat, farmacogenòmica, fenotip, farmacogenètica, farmacodinàmica, farmacocinètica, estereoselectivitat, epistaxi, enzim, enantiòmer, 3-diphenyl-1-pyrrolidine, 5-dimethyl-3, 3-diphenylpyrrolidine, electroforesi, EMDP, 2-ethyl-5-methyl-3, 2-ethylidene-1, dopamina, EDDP, criptocrom 1 (CRY1), desintoxicació, comorbiditat psiquiàtrica, Citocrom P4503A5, Citocrom P4503A4, Citocrom P4502D6, Citocrom P4502B6, Citocrom P4502C19, Citocrom P4502C9, Citocrom P4501A2, Citocrom P450, biodisponibilitat, Alel, addicció, abstinència, withdrawal, vulnerability, stereoselectivity, substance abuse, single nucleotide polymorphism (SNP), psychiatric comorbidity, replacement therapy, polymorphism, pharmacogenomics, pharmacokinetics, phenotype, pharmacogenetics, pharmacodynamics, opioid dependence, opioid, opiate, neurotrophins, neurotransmitter, Myocardin gene (MYOCD), resistant gene 1 (ABCB1), multidrug, methadone, mu opioid receptor, metabotropic glutamate receptors, maintenance treatment, Isomers, heroin (diacetylmorphine), Haplotype, Genotype, gene, Epistasis, Enzyme, Enantiomer, Electrophoresis, dopamine, detoxification, Cytochrome P4503A5, Cytochrome P4503A4, Cytochrome P4502D6, Cytochrome P4502C9, Cytochrome P4502C19, Cytochrome P4502B6, Cytochrome P4501A2, Cytochrome P450, Cryptochrome 1 gene (CRY1), craving, Complex Disease, candidate gene, allele, Brain Derived Neurotrophic factor (BDNF), addiction, heroïna (diacetilmorfina), isòmers, metadona, neurotransmissor, neurotrofines, opiacis, polimorfisme, polimorfisme de nucleòtid únic (SNP), receptor metabotròpic del glutamat, receptor opioide mu, tractament de manteniment, tractament substitutiu, trastorn per ús de substàncies, vulnerabilitat

وصف الملف: application/pdf

URL الوصول: http://www.tdx.cat/TDX-0301111-150109
http://hdl.handle.net/10803/7234

المؤلفون: Mwinyi, Jessica, Nekvindova, Jana, Cavaco, Isa, Hofmann, Yvonne, Pedersen, Rasmus Steen, Landman, Ellie, Mkrtchian, Souren, Ingelman-Sundberg, Magnus

مصطلحات موضوعية: Rat Granulosa-Cells, Cytochrome P4502C9, Nuclear Factor-4-Alpha, Cyp19 Expression, Heart, Hepatocyte-Nuclear-Factor-4-Alpha, Polymorphisms, Transporters, Metabolism, Activation

Relation: info:eu-repo/grantAgreement/FCT/SFRH/SFRH%2FBPD%2F34152%2F2006/PT; http://hdl.handle.net/10400.1/11665

الاتاحة: http://hdl.handle.net/10400.1/11665
https://doi.org/10.1124/dmd.109.029405

المؤلفون: Beinema, Maarten, Brouwers, Jacobus R. B. J., Schalekamp, Tom, Wilffert, Bob

المصدر: Beinema , M , Brouwers , J R B J , Schalekamp , T & Wilffert , B 2008 , ' Pharmacogenetic differences between warfarin, acenocoumarol and phenprocoumon ' , Thrombosis and Haemostasis , vol. 100 , no. 6 , pp. 1052-1057 . https://doi.org/10.1160/TH08-04-0116

مصطلحات موضوعية: Clinical trials, oral anticoagulants, pharamacogenetics, pharmacodynamics, ORAL ANTICOAGULANT-THERAPY, CYTOCHROME P4502C9, VITAMIN-K, DOSE REQUIREMENT, CYP2C9 GENOTYPES, IN-VITRO, CYP2C9-ASTERISK-3 ALLELES, BLEEDING COMPLICATIONS, GENETIC-DETERMINANTS, VKORC1

وصف الملف: application/pdf

الاتاحة: https://hdl.handle.net/11370/d08f4cd1-08a0-4cd9-bbb8-a1dcc519bee4
https://research.rug.nl/en/publications/d08f4cd1-08a0-4cd9-bbb8-a1dcc519bee4
https://doi.org/10.1160/TH08-04-0116
https://pure.rug.nl/ws/files/6727335/Beinema_2008_Thromb_Haemostasis.pdf

المؤلفون: Brändén, Gisela, 1975, Sjogren, T., Schnecke, V., Xue, Y. F.

المصدر: Drug Discovery Today. 19(7):905-911

مصطلحات موضوعية: Pharmacology and Toxicology, Farmakologi och toxikologi, HUMAN CYTOCHROME P4502C9, METABOLISM PREDICTIONS, FUNCTIONAL RELEVANCE, RITONAVIR ANALOGS, 3A4, BINDING, INSIGHTS, DOCKING, 2D6, P4503A4, Pharmacology & Pharmacy, ATES OF AMERICA, V107, P18422

URL الوصول: https://gup.ub.gu.se/publication/201608

المؤلفون: Yin, Sheng-Ju, Qi, Hui-Min, Wang, Xin, Zhang, Pu, Lu, Yuan, Wei, Min-Ji, Li, Pu, Qi, Guang-Zhao, Lou, Ya-Qing, Lu, Chuang, Zhang, Guo-Liang

المساهمون: Zhang, GL (reprint author), Peking Univ, Sch Basic Med Sci, Dept Pharmacol, Beijing 100191, Peoples R China., Lu, C (reprint author), Biogen, Dept Drug Metab & Pharmacokinet, Cambridge, MA 02142 USA., Peking Univ, Sch Basic Med Sci, Dept Pharmacol, Beijing 100191, Peoples R China., Peking Univ, Inst Clin Pharmacol, Dept Pharmacokinet, Hosp 1, Beijing, Peoples R China., Biogen, Dept Drug Metab & Pharmacokinet, Cambridge, MA 02142 USA.

المصدر: SCI

مصطلحات موضوعية: ABCB1 transporter, Chinese Han individuals, CYP2C8, CYP3A5, CYP2C9, genetic polymorphisms, pharmacokinetics, pioglitazone, CYP2C8 POLYMORPHISM FREQUENCIES, IMPAIRED GLUCOSE-TOLERANCE, IN-VITRO ASSESSMENT, CYTOCHROME P4502C9, DIABETES-MELLITUS, POPULATION, METABOLISM, IMPACT, PHARMACOGENOMICS, VOLUNTEERS

Relation: PHARMACOGENETICS AND GENOMICS.2017,27(4),125-134.; 1908756; http://hdl.handle.net/20.500.11897/474376; WOS:000398197800001

الاتاحة: https://hdl.handle.net/20.500.11897/474376
https://doi.org/10.1097/FPC.0000000000000265

المؤلفون: Ahlström, Marie, 1977, Ridderström, Marianne, Zamora, Ismael

المصدر: JOURNAL OF MEDICINAL CHEMISTRY. 50(22):5382-5391

مصطلحات موضوعية: Other Clinical Medicine, Annan klinisk medicin, human cytochrome p4502c9, favorable binding-sites, drug-metabolism, in-silico, enzyme, celecoxib, models, tool, 2c9

URL الوصول: https://gup.ub.gu.se/publication/80634

المؤلفون: Ahlström, M. M., Ridderström, M., Zamora, I., Luthman, Kristina, 1953

المصدر: Journal of Medicinal Chemistry. 50(18):4444-4452

مصطلحات موضوعية: Chemical Sciences, Kemi, HUMAN CYTOCHROME P4502C9, 5-DIARYLPYRAZOLE CLASS, DRUG-METABOLISM, CELECOXIB, OXIDATION, CYCLOOXYGENASE-2, BINDING, 2C9, IDENTIFICATION, FLURBIPROFEN

URL الوصول: https://gup.ub.gu.se/publication/61243

المؤلفون: Maarten J. Beinema, Jacobus R. B. J. Brouwers, Bob Wilffert, Tom Schalekamp

المصدر: Thrombosis and Haemostasis. 100(6):1052-1057

مصطلحات موضوعية: ORAL ANTICOAGULANT-THERAPY, CYP2C9 GENOTYPES, medicine.drug_class, Pharmacology, Phenprocoumon, Clinical trials, pharmacodynamics, Medicine, heterocyclic compounds, oral anticoagulants, VITAMIN-K, DOSE REQUIREMENT, CYP2C9, Acenocoumarol, business.industry, Anticoagulant, Warfarin, Hematology, IN-VITRO, BLEEDING COMPLICATIONS, VKORC1, CYP2C9-ASTERISK-3 ALLELES, Pharmacodynamics, CYTOCHROME P4502C9, GENETIC-DETERMINANTS, business, Pharmacogenetics, medicine.drug, pharamacogenetics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ad3e247cf4420ee58cf770ac8ee540
https://hdl.handle.net/11370/d08f4cd1-08a0-4cd9-bbb8-a1dcc519bee4

المصدر: Thrombosis and Haemostasis. 100(6):1052-1057

مصطلحات موضوعية: ORAL ANTICOAGULANT-THERAPY, CYP2C9 GENOTYPES, IN-VITRO, BLEEDING COMPLICATIONS, VKORC1, Clinical trials, CYP2C9-ASTERISK-3 ALLELES, CYTOCHROME P4502C9, pharmacodynamics, GENETIC-DETERMINANTS, oral anticoagulants, VITAMIN-K, DOSE REQUIREMENT, pharamacogenetics

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dris___01423::bb6dd919d665b45c4fb4248432072044
https://research.rug.nl/en/publications/d08f4cd1-08a0-4cd9-bbb8-a1dcc519bee4

المؤلفون: Jan van der Meer, Petra H. de Jong, Merel van Wijnen, Har J. M. Salden, Maarten J. Beinema, Jacobus R. B. J. Brouwers

المصدر: Molecular diagnosis & therapy, 11(2), 123-128. ADIS INT LTD
Molecular Diagnosis & Therapy, 11, 123-8
Molecular Diagnosis & Therapy, 11, 2, pp. 123-8

مصطلحات موضوعية: Male, ORAL ANTICOAGULANT-THERAPY, Cost effectiveness, Arthroplasty, Replacement, Hip, Gastroenterology, Drug Interactions, heterocyclic compounds, Heart, lung and circulation [UMCN 2.1], Prospective cohort study, Aged, 80 and over, Acenocoumarol, ALLELIC VARIANTS, Anti-Inflammatory Agents, Non-Steroidal, MOLECULAR-WEIGHT HEPARIN, NONSTEROIDAL ANTIINFLAMMATORY DRUGS, General Medicine, Middle Aged, Pathogenesis and modulation of inflammation [N4i 1], Treatment Outcome, OPTIMAL INTENSITY, CYTOCHROME P4502C9, Anesthesia, Molecular Medicine, Female, Aryl Hydrocarbon Hydroxylases, Infection and autoimmunity [NCMLS 1], medicine.drug, Adult, medicine.medical_specialty, ACENOCOUMAROL, WARFARIN, Invasive mycoses and compromised host [N4i 2], Pharmacotherapy, Internal medicine, Genetics, medicine, Humans, Elective surgery, CYP2C9, Aged, Cytochrome P-450 CYP2C9, Pharmacology, VENOUS THROMBOEMBOLISM, Polymorphism, Genetic, business.industry, Warfarin, Anticoagulants, BLEEDING COMPLICATIONS, Concomitant, Polypharmacy, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce7bf78cec7b06cfe8c2526901249d04
https://doi.org/10.1007/bf03256232

المؤلفون: Eibert R. Heerdink, Anthonius de Boer, Diederick E. Grobbee, Huibert Burger, Özlem Bozkurt, Olaf H. Klungel

المساهمون: Faculteit Medische Wetenschappen/UMCG, Interdisciplinary Centre Psychopathology and Emotion regulation (ICPE), Reproductive Origins of Adult Health and Disease (ROAHD), Life Course Epidemiology (LCE)

المصدر: Molecular diagnosis & therapy, 11(5), 291-302. ADIS INT LTD

مصطلحات موضوعية: medicine.medical_specialty, TRANSPORTING POLYPEPTIDE 1B1, TYPE-2 DIABETES-MELLITUS, LIPOPROTEIN-LIPASE, Biology, KOREAN POPULATION, Cytochrome P-450 Enzyme System, Diabetes mellitus, Internal medicine, Genetics, medicine, Humans, Hypoglycemic Agents, Pharmacology, Polymorphism, Genetic, Adiponectin, Type 2 Diabetes Mellitus, General Medicine, medicine.disease, TRANSCRIPTIONAL COACTIVATOR PGC-1, Metformin, PPAR gamma, GENETIC-POLYMORPHISM, Endocrinology, Pharmacogenetics, CYTOCHROME P4502C9, Molecular Medicine, Gene polymorphism, COMMON POLYMORPHISMS, Rosiglitazone, Pioglitazone, STOP-NIDDM TRIAL, medicine.drug, HEALTHY-VOLUNTEERS

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::821bddd0fe6918b1d468cb13928e1387
https://doi.org/10.1007/bf03256250

المؤلفون: Fohner, Alison E., Robinson, Renee, Yracheta, Joseph, Dillard, Denise A., Schilling, Brian, Khan, Burhan, Hopkins, Scarlett, Boyer, Bert B., Black, Jynene, Wiener, Howard, Tiwari, Hemant K., Gordon, Adam, Nickerson, Deborah, Tsai, Jesse M., Farin, Federico M., Thornton, Timothy A., Rettie, Allan E., Thummel, Kenneth E.

مصطلحات موضوعية: Atrial-Fibrillation, Pharmacogenetic Research, Cytochrome P4502C9, Drug, Variants, Stroke, Polymorphisms, Genotypes, Mortality, Mutation, 1311 Genetics, 1312 Molecular Biology, 1313 Molecular Medicine, 2716 Genetics (clinical)

Relation: orcid:0000-0001-6695-4366; U01 GM092676

الاتاحة: https://espace.library.uq.edu.au/view/UQ:31f467b

المؤلفون: GÜNEY, AHMET İLTER, ONAT, FİLİZ, ULUCAN, KORKUT

المساهمون: Ozkaynakci, Aydan, Gulcebi, Medine Idrizoglu, Ergec, Deniz, Ulucan, Korkut, Uzan, Mustafa, Ozkara, Cigdem, Guney, Ilter, Onat, Filiz Yilmaz

مصطلحات موضوعية: Epilepsy, Phenytoin, Pharmacogenomics, Pharmacokinetics, Pharmacotherapy, Metabolism enzyme, JAPANESE EPILEPTIC PATIENTS, GENETIC-POLYMORPHISM, ANTIEPILEPTIC DRUGS, CYTOCHROME P4502C9, CYP2C SUBFAMILY, HYDROXYLATION, FREQUENCIES, POPULATION, VARIANTS

Relation: NEUROLOGICAL SCIENCES; https://hdl.handle.net/11424/233509; WOS:000350365000007

الاتاحة: https://hdl.handle.net/11424/233509
https://doi.org/10.1007/s10072-014-1961-8

المؤلفون: Hanley, Michael J, Masse, Gina, Harmatz, Jerold S, Cancalon, Paul F, Dolnikowski, Gregory G, Court, Michael H, Greenblatt, David J

مصطلحات موضوعية: cytochrome P4503A, grapefruit juice, buspirone, blueberry juice, cytochrome P4502C9, flurbiprofen

Relation: ispartof: British journal of clinical pharmacology spage 1041 epage 1052 issue 4 vol 75; PMC3612722; WOS:000316326200017; 2376/108147; 99900547212401842; alma:01ALLIANCE_WSU/bibs/99900547212401842

الاتاحة: https://doi.org/10.1111/j.1365-2125.2012.04450.x
https://rex.libraries.wsu.edu/esploro/outputs/journalArticle/Effect-of-blueberry-juice-on-clearance/99900547212401842

المؤلفون: Verhoef, T.I., Redekop, W.K., Darba, J., Geitona, M., Hughes, D.A., Siebert, U., Boer, A. de, Zee, A.H.M.V.D., EU-PACT Grp

المصدر: Pharmacogenomics

مصطلحات موضوعية: coumarins CYP2C9 economics pharmacogenetics VKORC1 oral anticoagulant-therapy international normalized ratio warfarin therapy bleeding complications atrial-fibrillation cytochrome p4502c9 economic outcomes dose requirement cyp2c9 vkorc1

Relation: lumc-id: 5657494; https://hdl.handle.net/1887/116743

الاتاحة: https://hdl.handle.net/1887/116743
https://doi.org/10.2217/pgs.10.74

المؤلفون: George, Jacob, Doney, Alex, Palmer, Colin N., Lang, Chim C.

المصدر: George , J , Doney , A , Palmer , C N & Lang , C C 2010 , ' Pharmacogenetics testing : implications for cardiovascular therapeutics with clopidogrel and warfarin ' , Cardiovascular Therapeutics , vol. 28 , no. 3 , pp. 135-138 . https://doi.org/10.1111/j.1755-5922.2010.00176.x

مصطلحات موضوعية: Clopidogrel, Pharmacogenetics, Warfarin, ACUTE MYOCARDIAL-INFARCTION, ACUTE CORONARY SYNDROMES, ST-SEGMENT ELEVATION, CYTOCHROME P4502C9, POLYMORPHISMS, CYP2C9, GENOTYPE, THERAPY, ASPIRIN, ASSOCIATION

Relation: https://discovery.dundee.ac.uk/en/publications/b0f2d17e-a423-4375-86b7-553ebcc7800c

الاتاحة: https://discovery.dundee.ac.uk/en/publications/b0f2d17e-a423-4375-86b7-553ebcc7800c
https://doi.org/10.1111/j.1755-5922.2010.00176.x
http://www.scopus.com/inward/record.url?scp=77952162768&partnerID=8YFLogxK

المؤلفون: Kennerly, EM, Idaghdour, Y, Olby, NJ, Munana, KR, Gibson, G

المساهمون: Eichelbaum, M.

مصطلحات موضوعية: canine epilepsy, drug response, epoxide hydrolase, GABRA2, KCNQ3, pharmacogenetics, phenobarbital, SCN2A2, TEMPORAL-LOBE EPILEPSY, RESISTANT RATS DIFFER, IDIOPATHIC EPILEPSY, POTASSIUM-BROMIDE, SEIZURE CLASSIFICATION, ANTIEPILEPTIC DRUGS, CYTOCHROME P4502C9, FEBRILE SEIZURES, DOMESTIC DOG, C1, 970107 Expanding Knowledge in the Agricultural and Veterinary Sciences, 0604 Genetics

الاتاحة: https://espace.library.uq.edu.au/view/UQ:189848

المؤلفون: Jiang, Dechun, Bai, Xiangrong, Zhang, Qingxia, Lu, Wei, Wang, Yuqin, Li, Lin, Mueller, Markus

المساهمون: Wang, YQ (reprint author), Capital Med Univ, Dept Pharm, Xuanwu Hosp, Beijing 100053, Peoples R China., Capital Med Univ, Dept Pharm, Xuanwu Hosp, Beijing 100053, Peoples R China., Peking Univ, Sch Pharmaceut Sci, Beijing 100083, Peoples R China., Capital Med Univ, Dept Pharmacol, Educ Minist, Key Lab Neurodegenerat Dis,Xuanwu Hosp, Beijing 100053, Peoples R China., Vienna Med Univ, Dept Clin Pharmacol, A-1090 Vienna, Austria.

المصدر: SCI

مصطلحات موضوعية: CYP2C19, CYP2C9, Genotype, Valproic acid, NONMEM, Population pharmacokinetics, CYTOCHROME P4502C9, JAPANESE PATIENTS, CLINICAL-DATA, POLYMORPHISMS, METABOLISM, VALIDATION, VOLUNTEERS, MICROSOMES, PHENYTOIN

Relation: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY.2009,65,(12),1187-1193.; 933921; http://hdl.handle.net/20.500.11897/245021; WOS:000271949400004

الاتاحة: https://hdl.handle.net/20.500.11897/245021
https://doi.org/10.1007/s00228-009-0712-x

المؤلفون: Tai, Guoying, Dickmann, Leslie J., Matovic, Nicholas, DeVoss, James J., Gillam, Elizabeth M. J., Rettie, Allan E.

المساهمون: Halpert, J R

مصطلحات موضوعية: HUMAN CYTOCHROME P4502C9, ACTIVE-SITE, SPECIFICITY, DETERMINANTS, METABOLISM, WARFARIN, 2D6, IDENTIFICATION, PROPRANOLOL, RESIDUES, C1, 0601 Biochemistry and Cell Biology, 060107 Enzymes

Relation: orcid:0000-0002-2659-5140; orcid:0000-0003-0378-793X; P01 GM032165-25

الاتاحة: https://espace.library.uq.edu.au/view/UQ:170478

المؤلفون: Fonseca Casals, Francina

المساهمون: Torrens, Marta, Torre Fornell, Rafael de la, Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut

المصدر: TDX (Tesis Doctorals en Xarxa)
TDR. Tesis Doctorales en Red
instname

مصطلحات موضوعية: epistaxi, Cytochrome P450, Alel, neurotrophins, biodisponibilitat, polimorfisme de nucleòtid únic (SNP), EMDP, polymorphism, methadone, Cytochrome P4503A5, Cytochrome P4503A4, Haplotype, desintoxicació, abstinència, gen resistència multisubstància (ABCB1), enzim, Myocardin gene (MYOCD), pharmacogenetics, gen candidat, Enantiomer, Brain Derived Neurotrophic factor (BDNF), withdrawal, allele, criptocrom 1 (CRY1), comorbiditat psiquiàtrica, 2-ethyl-5-methyl-3, dopamina, enantiòmer, addiction, dopamine, genotip, receptor opioide mu, Citocrom P4502C19, Electrophoresis, Genotype, phenotype, vulnerabilitat, EDDP, estereoselectivitat, gen miocardina (MYOCD), stereoselectivity, polimorfisme, Citocrom P4502B6, trastorn per ús de substàncies, single nucleotide polymorphism (SNP), pharmacodynamics, detoxification, pharmacogenomics, maintenance treatment, craving, tractament substitutiu, farmacocinètica, opioid dependence, Enzyme, Cytochrome P4502D6, Citocrom P4501A2, Epistasis, heroin (diacetylmorphine), tractament de manteniment, multidrug, metabotropic glutamate receptors, vulnerability, resistant gene 1 (ABCB1), mu opioid receptor, Citocrom P4502C9, farmacogenòmica, 3-diphenyl-1-pyrrolidine, Citocrom P4502D6, Isomers, Cytochrome P4502C9, metadona, neurotransmissor, neurotrofines, substance abuse, Cytochrome P4501A2, fenotip, farmacogenètica, haplotip, Cytochrome P4502C19, opiate, opiacis, psychiatric comorbidity, Complex Disease, Cytochrome P4502B6, 2-ethylidene-1, pharmacokinetics, neurotransmitter, gen, 5-dimethyl-3, electroforesi, Cryptochrome 1 gene (CRY1), heroïna (diacetilmorfina), replacement therapy, gene, farmacodinàmica, receptor metabotròpic del glutamat, candidate gene, Citocrom P450, Citocrom P4503A4, Citocrom P4503A5, addicció, opioid, isòmers, 3-diphenylpyrrolidine

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::bd7b1e3d2f295cb3c1cef659e666f7de
http://hdl.handle.net/10803/7234