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1Academic Journal
المؤلفون: Liu, J., Kulkarni, A., Gao, Y.Q., Urul, D.A., Hamelin, R., Novotny, B.Á., Long, MJC, Aye, Y.
المصدر: Cell, vol. 187, no. 26, pp. 7450-7469.e29
مصطلحات موضوعية: Caenorhabditis elegans/metabolism, Animals, Caenorhabditis elegans Proteins/metabolism, Cysteine/metabolism, Organ Specificity, Cytochrome P-450 Enzyme System/metabolism, Humans, Stress, Physiological, 4-hydroxynonenal, C. elegans, cytochrome P450, function-guided spatial mapping, organ-specific responsivity profiling, proximity labeling proteomics, reactive metabolite signaling, tissue-specific stress response
وصف الملف: application/pdf
Relation: info:eu-repo/semantics/altIdentifier/pmid/39504959; info:eu-repo/semantics/altIdentifier/eissn/1097-4172; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_1CF6F7E9AF784; https://serval.unil.ch/notice/serval:BIB_1CF6F7E9AF78; https://serval.unil.ch/resource/serval:BIB_1CF6F7E9AF78.P001/REF.pdf
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2Academic Journal
المؤلفون: Damoiseaux, David, Schinkel, Alfred H, Beijnen, Jos H, Huitema, Alwin D R, Dorlo, Thomas P C
المساهمون: Apotheek O&O&O, Cancer
مصطلحات موضوعية: Animals, Cytochrome P-450 CYP3A/metabolism, Cytochrome P-450 Enzyme System/metabolism, Drug Interactions, Humans, Mice, Transgenic, Models, Animal, General Biochemistry,Genetics and Molecular Biology, General Neuroscience, Pharmacology, Toxicology and Pharmaceutics(all), Meta-Analysis, Journal Article, Review
وصف الملف: application/pdf
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3Academic Journal
المؤلفون: El Biali, Myriam, Wölfl-Duchek, Michael, Jackwerth, Matthias, Mairinger, Severin, Weber, Maria, Bamminger, Karsten, Poschner, Stefan, Rausch, Ivo, Schindler, Natalie, Lozano, Irene Hernández, Jäger, Walter, Nics, Lukas, Tournier, Nicolas, Hacker, Marcus, Zeitlinger, Markus, Bauer, Martin, Langer, Oliver
المصدر: ISSN: 1752-8054 ; Clinical and translational science, vol. 17, no. 5 (2024) e13804.
مصطلحات موضوعية: info:eu-repo/classification/ddc/617, Humans, Hypericum / chemistry, Blood-Brain Barrier / metabolism, Blood-Brain Barrier / drug effects, Plant Extracts / pharmacology, Male, Adult, Positron-Emission Tomography / methods, Female, Young Adult, ATP Binding Cassette Transporter, Subfamily B, Member 1 / metabolism, Subfamily B / metabolism, Cytochrome P-450 Enzyme System / metabolism, Healthy Volunteers
Relation: info:eu-repo/semantics/altIdentifier/pmid/38700454; https://archive-ouverte.unige.ch/unige:178286; unige:178286
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4Academic Journal
المؤلفون: Katariya, Mona M, Snee, Matthew, Tunnicliffe, Richard B, Kavanagh, Madeline E, Boshoff, Helena I M, Amadi, Cecilia N, Levy, Colin W, Munro, Andrew W, Abell, Chris, Leys, David, Coyne, Anthony G, McLean, Kirsty J
المصدر: Katariya , M M , Snee , M , Tunnicliffe , R B , Kavanagh , M E , Boshoff , H I M , Amadi , C N , Levy , C W , Munro , A W , Abell , C , Leys , D , Coyne , A G & McLean , K J 2023 , ' Structure Based Discovery of Inhibitors of CYP125 and CYP142 from Mycobacterium tuberculosis ' , Chemistry: A European Journal , vol. 29 , no. 29 , e202203868 . https://doi.org/10.1002/chem.202203868
مصطلحات موضوعية: Mycobacterium tuberculosis, Cytochrome P-450 Enzyme System/metabolism, Cholesterol/chemistry, Drug Discovery, Antitubercular Agents/pharmacology
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5Academic Journal
المؤلفون: Iversen, Ditte B, Dunvald, Ann-Cathrine Dalgård, Jespersen, Daniel M, Nielsen, Flemming, Brøsen, Kim, Damkier, Per, Hammer, Helen S, Pötz, Oliver, Järvinen, Erkka, Stage, Tore B
المصدر: Iversen , D B , Dunvald , A-C D , Jespersen , D M , Nielsen , F , Brøsen , K , Damkier , P , Hammer , H S , Pötz , O , Järvinen , E & Stage , T B 2023 , ' Flucloxacillin is a weak inducer of CYP3A4 in healthy adults and 3D spheroid of primary human hepatocytes ' , Clinical Pharmacology and Therapeutics , vol. 114 , no. 2 , pp. 434-445 . https://doi.org/10.1002/cpt.2959
مصطلحات موضوعية: Adult, Cytochrome P-450 CYP3A/genetics, Cytochrome P-450 Enzyme System/metabolism, Drug Interactions, Floxacillin/pharmacology, Hepatocytes/metabolism, Humans, RNA, Messenger
وصف الملف: application/pdf
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6Academic Journal
المؤلفون: Iversen, Ditte B, Andersen, Nanna Elman, Dalgård Dunvald, Ann-Cathrine, Pottegård, Anton, Stage, Tore B
المصدر: Iversen , D B , Andersen , N E , Dalgård Dunvald , A-C , Pottegård , A & Stage , T B 2022 , ' Drug metabolism and drug transport of the 100 most prescribed oral drugs ' , Basic & Clinical Pharmacology & Toxicology , vol. 131 , no. 5 , pp. 311-324 . https://doi.org/10.1111/bcpt.13780
مصطلحات موضوعية: ADME, CYP3A4, P-gp, drug metabolism, drug transport, ATP Binding Cassette Transporter, Subfamily G, Member 2, Subfamily B, Member 1/metabolism, Membrane Transport Proteins/metabolism, Cytochrome P-450 CYP1A2/metabolism, Cytochrome P-450 CYP3A/metabolism, Cytochrome P-450 CYP2C19/metabolism, Cytochrome P-450 CYP2C9/metabolism, Cytochrome P-450 CYP2D6/metabolism, Cytochrome P-450 CYP2C8/metabolism, Cytochrome P-450 Enzyme System/metabolism, Microsomes, Liver, Neoplasm Proteins/metabolism
وصف الملف: application/pdf
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7Academic Journal
المؤلفون: Li, J., Brandalise, D., Coste, A.T., Sanglard, D., Lamoth, F.
المصدر: Antimicrobial agents and chemotherapy, vol. 68, no. 12, pp. e0126524
مصطلحات موضوعية: Antifungal Agents/pharmacology, Drug Resistance, Fungal/genetics, Microbial Sensitivity Tests, Azoles/pharmacology, Fungal Proteins/genetics, Fungal Proteins/metabolism, Candida auris/genetics, Candida auris/drug effects, Fluconazole/pharmacology, Humans, Mutation, Transcription Factors/genetics, Transcription Factors/metabolism, Candidiasis/microbiology, Candidiasis/drug therapy, Cytochrome P-450 Enzyme System/genetics, Cytochrome P-450 Enzyme System/metabolism, drug transporters, fluconazole, mitochondria, transcription factors
Relation: info:eu-repo/semantics/altIdentifier/pmid/39480072; info:eu-repo/semantics/altIdentifier/eissn/1098-6596; https://serval.unil.ch/notice/serval:BIB_833F84ADFDA1
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8Academic Journal
المؤلفون: Loerracher, Ann-Kathrin, Braunbeck, Thomas
المصدر: http://lobid.org/resources/99370671250806441#!, 95(7):2299-2334.
مصطلحات موضوعية: Xenobiotic metabolism, Zebrafish Proteins/genetics [MeSH], Biotransformation, Biotransformation [MeSH], Zebrafish, Review Article, Embryo, Nonmammalian/metabolism [MeSH], Ecotoxicology, Mammals/metabolism [MeSH], Animals [MeSH], Cytochrome P-450 Enzyme System/metabolism [MeSH], Cytochrome P-450 Enzyme System/genetics [MeSH], Zebrafish [MeSH], Toxicology, Cytochrome P450
Relation: https://repository.publisso.de/resource/frl:6451681; https://doi.org/10.1007/s00204-021-03071-7; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8241672/
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9Academic Journal
المؤلفون: Achour, Brahim, Al-Majdoub, Zubida, Grybos‐Gajniak, Agnieszka, Lea, Kristi, Kilford, Peter, Zhang, Mian, Knight, David, Barber, Jill, Schageman, Jeoffrey, Rostami-Hodjegan, Amin
المصدر: Achour , B , Al-Majdoub , Z , Grybos‐Gajniak , A , Lea , K , Kilford , P , Zhang , M , Knight , D , Barber , J , Schageman , J & Rostami-Hodjegan , A 2021 , ' Liquid Biopsy Enables Quantification of the Abundance and Interindividual Variability of Hepatic Enzymes and Transporters ' , Clinical Pharmacology & Therapeutics , vol. 109 , no. 1 , pp. 222-232 . https://doi.org/10.1002/cpt.2102
مصطلحات موضوعية: Adult, Aged, 80 and over, Biological Transport/physiology, Cytochrome P-450 Enzyme System/metabolism, Exosomes/metabolism, Female, Humans, Inactivation, Metabolic/physiology, Liquid Biopsy/methods, Liver/metabolism, Male, Membrane Transport Proteins/metabolism, Metabolic Clearance Rate/physiology, Middle Aged, Young Adult
وصف الملف: application/pdf
الاتاحة: https://research.manchester.ac.uk/en/publications/b9fd9968-9b26-4bbd-86d5-02a543c2b98d
https://doi.org/10.1002/cpt.2102
https://pure.manchester.ac.uk/ws/files/178476774/Achour_etal_2020_cpt.2102.pdf
http://www.scopus.com/inward/record.url?scp=85096758140&partnerID=8YFLogxK
https://ascpt.onlinelibrary.wiley.com/doi/abs/10.1002/cpt.2102 -
10Academic Journal
المؤلفون: Al-Majdoub, Zubida, Couto, Narciso, Achour, Brahim, Harwood, Matthew D, Carlson, Gordon, Warhurst, Geoffrey, Barber, Jill, Rostami-Hodjegan, Amin
المصدر: Al-Majdoub , Z , Couto , N , Achour , B , Harwood , M D , Carlson , G , Warhurst , G , Barber , J & Rostami-Hodjegan , A 2021 , ' Quantification of Proteins Involved in Intestinal Epithelial Handling of Xenobiotics ' , Clinical Pharmacology & Therapeutics , vol. 109 , no. 4 , pp. 1136-1146 . https://doi.org/10.1002/cpt.2097
مصطلحات موضوعية: Alkaline Phosphatase/metabolism, Cytochrome P-450 Enzyme System/metabolism, Enzymes/metabolism, Humans, Ileum/metabolism, Intestinal Mucosa/metabolism, Jejunum/metabolism, Models, Biological, Oxygenases/metabolism, Proteins/metabolism, Proteomics, Thioredoxins/metabolism, Tight Junction Proteins/metabolism, Transferases/metabolism, Xenobiotics/pharmacokinetics
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11Academic Journal
المؤلفون: Yevtodiyenko, A., Bazhin, A., Khodakivskyi, P., Godinat, A., Budin, G., Maric, T., Pietramaggiori, G., Scherer, S.S., Kunchulia, M., Eppeldauer, G., Polyakov, S.V., Francis, K.P., Bryan, J.N., Goun, E.A.
المصدر: Nature communications, vol. 12, no. 1, pp. 2680
مصطلحات موضوعية: Animals, Genetically Modified, Biological Phenomena, Cytochrome P-450 Enzyme System/chemistry, Cytochrome P-450 Enzyme System/metabolism, Diagnostic Imaging/methods, Dipeptidyl Peptidase 4/chemistry, Dipeptidyl Peptidase 4/metabolism, Dogs, Firefly Luciferin/chemistry, Firefly Luciferin/metabolism, Humans, Luciferases/chemistry, Luciferases/genetics, Luciferases/metabolism, Luminescent Measurements/instrumentation, Luminescent Measurements/methods, Models, Animal, Molecular Structure, Reproducibility of Results
وصف الملف: application/pdf
Relation: info:eu-repo/semantics/altIdentifier/pmid/33976191; info:eu-repo/semantics/altIdentifier/eissn/2041-1723; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_40EAFDED28F64; https://serval.unil.ch/notice/serval:BIB_40EAFDED28F6; https://serval.unil.ch/resource/serval:BIB_40EAFDED28F6.P001/REF.pdf
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12Academic Journal
المؤلفون: Lenoir, Camille, Terrier, Jean, Gloor, Yvonne Sylvia, Curtin, François, Rollason, Victoria, Desmeules, Jules Alexandre, Daali, Youssef, Reny, Jean-Luc, Samer, Caroline Flora
المصدر: ISSN: 0009-9236 ; Clinical pharmacology and therapeutics, vol. 110, no. 5 (2021) p. 1358-1367.
مصطلحات موضوعية: info:eu-repo/classification/ddc/615, info:eu-repo/classification/ddc/616, info:eu-repo/classification/ddc/617, Aged, 80 and over, C-Reactive Protein / metabolism, COVID-19 / blood, COVID-19 / enzymology, Cytochrome P-450 Enzyme System / genetics, Cytochrome P-450 Enzyme System / metabolism, Female, Genetic Variation, Humans, Interleukin-6 / blood, Linear Models, Male, Middle Aged, Models, Theoretical, Prospective Studies, Tumor Necrosis Factor-alpha / blood
Relation: info:eu-repo/semantics/altIdentifier/pmid/34473836; https://archive-ouverte.unige.ch/unige:161947; unige:161947
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13Academic Journal
المصدر: http://lobid.org/resources/99370671250806441#!, 95(1):117-133.
مصطلحات موضوعية: Xenobiotic metabolism, Biotransformation [MeSH], Mice, Inbred C57BL [MeSH], Cell Line [MeSH], Pregnane X Receptor/metabolism [MeSH], Receptors, Cytoplasmic and Nuclear/metabolism [MeSH], Cytochrome P-450 Enzyme System/metabolism [MeSH], Azole fungicides, Toxicokinetics and Metabolism, Xenobiotics/metabolism [MeSH], SLC transporter, Species Specificity [MeSH], Biological Transport [MeSH], Humans [MeSH], Nuclear receptors, Pharmaceutical Preparations/metabolism [MeSH], Membrane Transport Proteins/metabolism [MeSH], Humanized mouse models, Animals [MeSH], Hepatocytes, Liver/enzymology [MeSH], ABC transporter, Rats, Wistar [MeSH], Cytochrome P450, Substrate Specificity [MeSH], TXP, Isoenzymes [MeSH]
Relation: https://repository.publisso.de/resource/frl:6466370; https://doi.org/10.1007/s00204-020-02939-4; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7811513/
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14Academic Journal
المؤلفون: Thorsteinsson, Kristina, Lebech, Anne-Mette, Dalhoff, Kim Peder, Wilken-Jensen, Charlotte, Katzenstein, Terese Lea
المصدر: Ugeskrift for Laeger. 181(7):603
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15Academic Journal
المؤلفون: ter Avest, M., Veringa, A., van den Heuvel, E.R., Kosterink, J.G.W., Schölvinck, E.H., Tissing, W.J.E., Alffenaar, J.W.C.
المصدر: ter Avest , M , Veringa , A , van den Heuvel , E R , Kosterink , J G W , Schölvinck , E H , Tissing , W J E & Alffenaar , J W C 2017 , ' The effect of inflammation on voriconazole through concentrations in children ' , British Journal of Clinical Pharmacology , vol. 83 , no. 3 , pp. 678-680 . https://doi.org/10.1111/bcp.13151
مصطلحات موضوعية: Adolescent, Adult, Age Factors, Antifungal Agents/pharmacokinetics, Aspergillosis/blood, Biological Variation, Population, C-Reactive Protein/analysis, Child, Preschool, Cytochrome P-450 Enzyme System/metabolism, Drug Monitoring, Female, Humans, Inflammation/blood, Microsomes, Liver/metabolism, Retrospective Studies, Voriconazole/blood
وصف الملف: application/pdf
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16Academic Journal
المؤلفون: Boström, Lisa, Islander, Gunilla
المصدر: SFAI-tidningen. 22(3):168
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17Academic Journal
المساهمون: College of Medicine, Dept. of Laboratory Medicine, Min Ji Choi, Eun Jeong Won, Jong Hee Shin, Soo Hyun Kim, Wee-Gyo Lee, Mi-Na Kim, Kyungwon Lee, Myung Geun Shin, Soon Pal Suh, Dong Wook Ryang, Young Jun Im, Lee, Kyung Won
مصطلحات موضوعية: ATP-Binding Cassette Transporters/genetics, ATP-Binding Cassette Transporters/metabolism, ATP-Binding Cassette, Sub-Family B, Member 1/genetics, Member 1/metabolism, Amino Acid Substitution, Antifungal Agents/pharmacology, Candida tropicalis/drug effects, Candida tropicalis/genetics, Candida tropicalis/growth & development, Candida tropicalis/isolation & purification, Candidiasis/drug therapy, Candidiasis/etiology, Candidiasis/immunology, Candidiasis/microbiology, Cytochrome P-450 Enzyme System/genetics, Cytochrome P-450 Enzyme System/metabolism, Drug Resistance, Fungal/genetics, Female, Fluconazole/pharmacology, Fungal Proteins/genetics, Fungal Proteins/metabolism, Fungemia/drug therapy, Fungemia/etiology, Fungemia/immunology, Fungemia/microbiology, Gene Expression, Humans
Relation: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY; J00189; OAK-2016-05503; https://ir.ymlib.yonsei.ac.kr/handle/22282913/152105; T201603651; ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, Vol.60(6) : 3653-3661, 2016
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18Conference
المؤلفون: Forsen, Kent
المصدر: Svensk Cardiologi. (4):26
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19Academic Journal
المساهمون: College of Medicine, Dept. of Life Science, Yu Jin Jeon, Joong Sun Kim, Geun Hye Hwang, Zhexue Wu, Ho Jae Han, Soo Hyun Park, Woochul Chang, Lark Kyun Kim, You-Mie Lee, Kwang-Hyeon Liu, Min Young Lee, Kim, Lark Kyun
مصطلحات موضوعية: Animals, Antineoplastic Agents/pharmacology, Apoptosis/drug effects, Apoptosis Regulatory Proteins/metabolism, Astemizole/metabolism, Carcinoma, Hepatocellular/drug therapy, Hepatocellular/enzymology, Hepatocellular/genetics, Hepatocellular/pathology, Cell Survival/drug effects, Cytochrome P-450 Enzyme Inhibitors/pharmacology, Cytochrome P-450 Enzyme System/genetics, Cytochrome P-450 Enzyme System/metabolism, Dealkylation, Diterpenes, Abietane/pharmacology, Dose-Response Relationship, Drug, Female, Hep G2 Cells, Humans, Liver Neoplasms/drug therapy, Liver Neoplasms/enzymology, Liver Neoplasms/genetics, Liver Neoplasms/pathology, Mice, Inbred BALB C, Nude, Species Specificity
Relation: EUROPEAN JOURNAL OF PHARMACOLOGY; J00842; OAK-2015-07449; https://ir.ymlib.yonsei.ac.kr/handle/22282913/157312; https://www.sciencedirect.com/science/article/pii/S0014299915301722; T201506199; EUROPEAN JOURNAL OF PHARMACOLOGY, Vol.764 : 480-488, 2015
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20Academic Journal
المساهمون: College of Medicine, Dept. of Thoracic & Cardiovascular Surgery, Sook Hee An, Byung Chul Chang, Kyung Eun Lee, Hye Sun Gwak, Chang, Byung Chul
مصطلحات موضوعية: Aged, Anticoagulants/administration & dosage, Anticoagulants/adverse effects, Anticoagulants/pharmacokinetics, Blood Coagulation/drug effects, Cytochrome P-450 CYP2C9/genetics, Cytochrome P-450 CYP2C9/metabolism, Cytochrome P-450 Enzyme System/genetics, Cytochrome P-450 Enzyme System/metabolism, Cytochrome P450 Family 4, Drug Dosage Calculations, Drug Monitoring/methods, Female, Gene Frequency, Genotype, Glucuronosyltransferase/genetics, Glucuronosyltransferase/metabolism, Heart Valve Prosthesis, Heart Valve Prosthesis Implantation/adverse effects, Heart Valve Prosthesis Implantation/instrumentation, Humans, International Normalized Ratio, Linear Models, Male, Middle Aged, Multivariate Analysis, Pharmacogenetics, Phenotype, Polymorphism, Single Nucleotide
Relation: CARDIOVASCULAR THERAPEUTICS; J02905; OAK-2015-07418; https://ir.ymlib.yonsei.ac.kr/handle/22282913/157298; T201506169; CARDIOVASCULAR THERAPEUTICS, Vol.33(6) : 324-328, 2015
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