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المؤلفون: David J. Craik, Carsten Gründemann, Edin Muratspahić, Mina Vasileva, Peta J. Harvey, Johannes Koehbach, Christian W. Gruber, Roland Hellinger, Seema Devi
المصدر: ACS Chemical Biology. 16:2373-2386
مصطلحات موضوعية: Protein Conformation, Cell, Cyclotides, Peptide, 01 natural sciences, Biochemistry, Monocytes, 03 medical and health sciences, medicine, Humans, Structural motif, Cell Proliferation, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, 010405 organic chemistry, Chemistry, Cystine knot, Biological membrane, General Medicine, 0104 chemical sciences, Cyclotide, Cytosol, medicine.anatomical_structure, Biophysics, Molecular Medicine, Cystine Knot Motifs, Immunosuppressive Agents
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2Editing the cystine knot motif of MSTN enhances muscle development of Liang Guang Small Spotted pigs
المؤلفون: Peng, Dingwei, Li, Ruiqiang, Zeng, Wu, Wang, Min, Shi, Xuan, Zeng, Jianhua, Liu, Xiaohong, Chen, Yaoshen, He, Zuyong
المصدر: Yi chuan = Hereditas. 43(3)
مصطلحات موضوعية: Animals, Genetically Modified, Swine, Animals, Female, Cystine Knot Motifs, CRISPR-Cas Systems, Myostatin, Muscle Development
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المؤلفون: Jingtan Su, Julio A. Camarero, Maria Jose Campbell
المصدر: Methods Mol Biol
Expressed Protein Ligation ISBN: 9781071604335مصطلحات موضوعية: 0301 basic medicine, Protein Folding, Recombinant Fusion Proteins, Peptide, Cyclotides, 010402 general chemistry, Protein Engineering, 01 natural sciences, Epitope, Chromatography, Affinity, Article, Inteins, 03 medical and health sciences, Protein splicing, Escherichia coli, Disulfides, Cloning, Molecular, Chromatography, High Pressure Liquid, Plant Proteins, chemistry.chemical_classification, Oxidative folding, Cystine knot, Chromatography, Agarose, 0104 chemical sciences, Cyclotide, 030104 developmental biology, chemistry, Biochemistry, Cyclization, Cystine, Electrophoresis, Polyacrylamide Gel, Cystine Knot Motifs, Intein, Protein Processing, Post-Translational
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المؤلفون: Jacobsson, Erik, Andersson, Håkan S., Strand, Malin, Peigneur, Steve, Eriksson, Camilla, Lodén, Henrik, Shariatgorji, Mohammadreza, Andrén, Per E., Lebbe, Eline K. M., Rosengren, K. Johan, Tytgat, Jan, Göransson, Ulf
المصدر: Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reportsمصطلحات موضوعية: VENOM PEPTIDES, MARINE ECOSYSTEMS, Brachyura, NEMERTEA, ALPHA-SCORPION TOXIN, lcsh:Medicine, AMINO-ACID-SEQUENCE, Cockroaches, Voltage-Gated Sodium Channels, Article, Tandem Mass Spectrometry, Helminths, Drug Discovery, Exome Sequencing, Animals, Paralysis, lcsh:Science, Phylogeny, Sweden, Science & Technology, PURIFICATION, Venoms, lcsh:R, Biochemistry and Molecular Biology, SPIDER, Multidisciplinary Sciences, Mucus, SUBUNIT, Science & Technology - Other Topics, INSECTICIDAL NEUROTOXIN, lcsh:Q, Cystine Knot Motifs, Peptides, Biokemi och molekylärbiologi, TETRODOTOXIN, Chromatography, Liquid
وصف الملف: Electronic; application/pdf
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المؤلفون: David J. Adams, Muharrem Akcan, Mari D. Heghinian, Anne C. Conibear, David J. Craik, Frank Marí, Richard J. Clark, Andrew de Faoite, Norelle L. Daly, Talwar Sahil
المصدر: Biopolymers. 104:682-692
مصطلحات موضوعية: chemistry.chemical_classification, 0303 health sciences, 010405 organic chemistry, Organic Chemistry, Cystine knot, Biophysics, Peptide, General Medicine, Cystine Knot Motifs, Native chemical ligation, 01 natural sciences, Biochemistry, Combinatorial chemistry, Cyclic peptide, 0104 chemical sciences, Biomaterials, 03 medical and health sciences, chemistry, Cyclotides, Intramolecular force, Conotoxin, 030304 developmental biology
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المؤلفون: Glenn F. King, Volker Herzig
المصدر: Toxins, Vol 7, Iss 10, Pp 4366-4380 (2015)
Toxins
Volume 7
Issue 10
Pages 4366-4380مصطلحات موضوعية: physicochemical stability, Protein Conformation, Stereochemistry, Health, Toxicology and Mutagenesis, spider toxin, Spider Venoms, lcsh:Medicine, Cyclotides, Peptide, Cystine Knot Motifs, Biology, Toxicology, Article, thermal stability, Protein structure, Animals, Cysteine, ω-hexatoxin-Hv1a, proteolytic degradation, chemistry.chemical_classification, Protein Stability, insecticidal toxin, lcsh:R, Cystine knot, Spiders, inhibitor cystine knot, Spider toxin, Biological Control Agents, chemistry, Biochemistry, Inhibitor cystine knot
وصف الملف: application/pdf
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7
المؤلفون: Aaron G. Poth, Michelle L. Colgrave, David J. Craik, Anjaneya S. Ravipati, Quentin Kaas, Conan K. Wang, Sónia Troeira Henriques
المصدر: ResearcherID
ACS Chemical Biologyمصطلحات موضوعية: Models, Molecular, Spectrometry, Mass, Electrospray Ionization, Erythrocytes, Magnetic Resonance Spectroscopy, 060110 Receptors and Membrane Biology, cyclic cystine knot, De Novo Sequencing of cyclic peptides, Lysine, Cyclotides, Cystine Knot Motifs, Biochemistry, Subclass, Humans, Amino Acid Sequence, Cells, Cultured, biology, Host (biology), General Medicine, biology.organism_classification, 030406 Proteins and Peptides, Evolutionary biology, 030100 ANALYTICAL CHEMISTRY, peptide-membrane interactions, Plant species, Molecular Medicine, Melicytus chathamicus, Peptides, Disulfide-rich peptides, Violaceae, Protein Binding
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المؤلفون: Aaron G. Poth, Tunjung Mahatmanto, David J. Craik, Joshua S. Mylne
المصدر: Fitoterapia. 95:22-33
مصطلحات موضوعية: Momordica cochinchinensis, Formic acid, Molecular Sequence Data, Cyclotides, chemistry.chemical_compound, Drug Discovery, Organic chemistry, Momordica, Amino Acid Sequence, Acetonitrile, Plant Proteins, Pharmacology, Chromatography, biology, Plant Extracts, Extraction (chemistry), Cystine knot, food and beverages, General Medicine, biology.organism_classification, Ammonium bicarbonate, chemistry, Seeds, Solvents, Cystine Knot Motifs, Methanol, Sodium acetate
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المؤلفون: Richard H. Kimura, Yeongjin Hong, Hongguang Liu, Xiaohua Zhu, Xiang Hu, Chunxia Qin, Jinbo Li, Zhen Cheng, Paul D. Benny, Xiaowei Ma, Thomas R. Hayes, Sanjiv S. Gambhir
المصدر: Molecular Pharmaceutics
مصطلحات موضوعية: Biodistribution, Pathology, medicine.medical_specialty, Integrins, Cell, Integrin, Molecular Sequence Data, Pharmaceutical Science, Article, Mice, In vivo, Antigens, Neoplasm, Spect imaging, Cell Line, Tumor, Drug Discovery, medicine, Animals, Humans, Tissue Distribution, Amino Acid Sequence, 99mTc, Tomography, Emission-Computed, Single-Photon, biology, Cystine knot, integrin αvβ6, Neoplasms, Experimental, Organotechnetium Compounds, In vitro, 3. Good health, medicine.anatomical_structure, Cell culture, SPECT, biology.protein, Cancer research, Molecular Medicine, Female, Cystine Knot Motifs, Radiopharmaceuticals, Peptides, cystine-knot peptide
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المؤلفون: Shaikh Jamal, Uddin, Taj, Muhammad, Md, Shafiullah, Blazej, Slazak, Razina, Rouf, Ulf, Göransson
المصدر: Biopolymers. 108(3)
مصطلحات موضوعية: Animals, Cyclotides, Amino Acid Sequence, Cystine Knot Motifs, Rabbits, Antibodies, Chromatography, Affinity
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11
المؤلفون: Irina Vetter, Elizabeth L. Armitage, Glenn F. King, Kathryn G. George, Nikolaus M. Loening, Volker Herzig, Lisa E. Muñoz, Nathanial K. Ariki, Francesca R. Goodstein, Vanessa L. Smith
المصدر: PLoS ONE
PLoS ONE, Vol 11, Iss 5, p e0156291 (2016)مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Scytodes, Protein Conformation, lcsh:Medicine, Spider Venoms, Venom, Peptide, Toxicology, Pathology and Laboratory Medicine, Biochemistry, Medicine and Health Sciences, Toxins, Amino Acids, Post-Translational Modification, lcsh:Science, Peptide sequence, chemistry.chemical_classification, Multidisciplinary, Scytodes thoracica, biology, Organic Compounds, Spiders, Anatomy, Chemistry, Physical Sciences, Disulfide Bonds, Sequence Analysis, Research Article, Arthropoda, Toxic Agents, Research and Analysis Methods, complex mixtures, Gryllidae, 03 medical and health sciences, Sequence Motif Analysis, Arachnida, Animals, Sulfur Containing Amino Acids, Amino Acid Sequence, Cysteine, Spitting spider, Saliva, Molecular Biology Techniques, Sequencing Techniques, Molecular Biology, 030102 biochemistry & molecular biology, Sequence Homology, Amino Acid, Venoms, lcsh:R, Thoracica, Organic Chemistry, Organisms, Chemical Compounds, Biology and Life Sciences, Proteins, biology.organism_classification, Invertebrates, Peptide Fragments, 030104 developmental biology, chemistry, Predatory Behavior, lcsh:Q, Inhibitor cystine knot, Cystine Knot Motifs, Peptides, Sequence Alignment
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المؤلفون: Bryon E. Petersen, Huiming Xia, William W. Hauswirth, Liya Pi, Gregory S. Schultz, Anitha K. Shenoy, Edward W. Scott, Nikole Nelson, Seungbum Kim, Jianwen Liu
المصدر: The FASEB Journal. 26:3365-3379
مصطلحات موضوعية: Angiogenesis, medicine.medical_treatment, Mutant, Neovascularization, Physiologic, Cystine Knot Motifs, CDC42, Biology, Biochemistry, Research Communications, Neovascularization, Carcinoma, Lewis Lung, Mice, Two-Hybrid System Techniques, Human Umbilical Vein Endothelial Cells, Genetics, medicine, Animals, Humans, Molecular Biology, integumentary system, Growth factor, Connective Tissue Growth Factor, Membrane Proteins, Retinal Vessels, Cell biology, CTGF, Immunology, Ectopic expression, medicine.symptom, Biotechnology
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المؤلفون: Yanbin Ji, Andrew Gould, Julio A. Camarero, Teshome Leta Aboye
المصدر: Current Pharmaceutical Design. 17:4294-4307
مصطلحات موضوعية: Models, Molecular, Protein Conformation, Stereochemistry, Antineoplastic Agents, Cyclotides, Peptide, Cystine Knot Motifs, Biology, Crystallography, X-Ray, Article, Protein structure, Anti-Infective Agents, Drug Stability, Peptide Library, Drug Discovery, Animals, Humans, Amino Acid Sequence, Peptide library, Peptide sequence, Pharmacology, chemistry.chemical_classification, Protein Stability, Drug discovery, Cystine knot, Plants, Genetically Modified, chemistry, Biochemistry, Genetic Engineering
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المؤلفون: David J. Craik, Norelle L. Daly
المصدر: Current Opinion in Chemical Biology. 15:362-368
مصطلحات موضوعية: Protein Stability, Cystine knot, Chemical biology, Proteins, food and beverages, Cyclotides, Biology, Protein Engineering, Biochemistry, Analytical Chemistry, law.invention, Bioactive peptide, stomatognathic system, law, Alpha-Conotoxin, Recombinant DNA, Animals, Cystine Knot Motifs, Kappa-conotoxin PVIIA, Structural motif, Topology (chemistry)
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المؤلفون: Harald Kolmar
المصدر: Expert Review of Molecular Diagnostics. 10:361-368
مصطلحات موضوعية: Models, Molecular, Scaffold, Pathology, medicine.medical_specialty, Protein Conformation, Functional features, Molecular Sequence Data, Nanotechnology, Cystine Knot Motifs, Pathology and Forensic Medicine, Broad spectrum, Protein structure, Genetics, medicine, Animals, Humans, Amino Acid Sequence, Disulfides, Pathology, Molecular, Molecular Biology, Cystine-Knot Miniproteins, Tumor imaging, Chemistry, Proteins, Molecular Medicine, Clearance
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المصدر: Journal of Biological Chemistry. 285:10797-10805
مصطلحات موضوعية: Erythrocytes, Trichostrongylus, Lysine, Cyclotides, Cystine Knot Motifs, Biology, Hemolysis, Biochemistry, Animals, Humans, Structural motif, Molecular Biology, chemistry.chemical_classification, Sheep, Peptide chemical synthesis, Antinematodal Agents, Cystine knot, Trichostrongylosis, Cell Biology, Cyclic peptide, Cyclotide, Gastrointestinal Tract, chemistry, Larva, Protein Structure and Folding, Mutagenesis, Site-Directed, Haemonchus, Haemonchiasis
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المؤلفون: Hans-Ulrich Schmoldt, Harald Kolmar, Olga Avrutina, Christian P. Sommerhoff, Dusica Gabrijelcic-Geiger, Ulf Diederichsen
المصدر: Journal of Molecular Biology. 395:167-175
مصطلحات موضوعية: Models, Molecular, Recombinant Fusion Proteins, medicine.medical_treatment, Molecular Sequence Data, Cyclotides, Tryptase, Cystine Knot Motifs, Protein Engineering, 01 natural sciences, law.invention, 03 medical and health sciences, Tetramer, Structural Biology, law, medicine, Animals, Humans, Amino Acid Sequence, Molecular Biology, Cystine-Knot Miniproteins, 030304 developmental biology, 0303 health sciences, Protease, Sequence Homology, Amino Acid, biology, 010405 organic chemistry, Chemistry, Cystine knot, Protein engineering, 0104 chemical sciences, 3. Good health, Biochemistry, Structural Homology, Protein, biology.protein, Recombinant DNA, Cattle, Tryptases
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المؤلفون: Harald Kolmar
المصدر: Current Opinion in Pharmacology. 9:608-614
مصطلحات موضوعية: Models, Molecular, Protein Denaturation, Protein Conformation, Molecular Sequence Data, Protein design, Administration, Oral, Cyclotides, Cystine Knot Motifs, Protein Engineering, Structure-Activity Relationship, Protein structure, Peptide Library, Drug Discovery, Animals, Combinatorial Chemistry Techniques, Humans, Structure–activity relationship, Amino Acid Sequence, Peptide library, Cystine-Knot Miniproteins, Pharmacology, High rate, Binding Sites, Protein Stability, Chemistry, food and beverages, Protein engineering, Combinatorial chemistry, Biochemistry, Drug Design, Peptides
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المؤلفون: Norelle L. Daly, David J. Craik, K. Johan Rosengren
المصدر: Advanced Drug Delivery Reviews. 61:918-930
مصطلحات موضوعية: Protein Folding, Drug discovery, Molecular Sequence Data, Cystine knot, Pharmaceutical Science, Cyclotides, Hydrogen Bonding, Cystine Knot Motifs, Protein engineering, Biology, Protein Structure, Secondary, Cyclotide, Protein structure, Biochemistry, Drug Design, Drug Discovery, Amino Acid Sequence, Phylogeny, Function (biology)
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المؤلفون: SM Krakora, M Cunningham, JC Post, K Shen, M.K. Singh, Garth D. Ehrlich, Xue Wang, Fen Z. Hu
المصدر: Orthodontics & Craniofacial Research. 12:254-262
مصطلحات موضوعية: musculoskeletal diseases, Pathology, medicine.medical_specialty, Dura mater, Acrocephalosyndactylia, Transplantation, Heterologous, Orthodontics, Article, Cell Line, Craniosynostosis, Parietal Bone, Craniosynostoses, Rats, Nude, medicine, Animals, Humans, Cell Lineage, Receptor, Fibroblast Growth Factor, Type 2, Noggin, Osteoblasts, integumentary system, Chimera, business.industry, Craniofacial Dysostosis, Skull, Cranial Sutures, Anatomy, Synostosis, medicine.disease, Recombinant Proteins, Rats, Transplantation, Disease Models, Animal, medicine.anatomical_structure, Otorhinolaryngology, Bone Morphogenetic Proteins, Frontal Bone, Mutation, embryonic structures, Surgery, Cystine Knot Motifs, Dura Mater, Coronal suture, Oral Surgery, Carrier Proteins, business, Parietal bone