يعرض 1 - 20 نتائج من 14,579 نتيجة بحث عن '"Cyp3a"', وقت الاستعلام: 0.67s تنقيح النتائج
  1. 1
    Academic Journal
    Effect of CYP3A5*3 genotype on exposure and efficacy of quetiapine: A retrospective, cohort study.

    المؤلفون: Zhao, Yan1 (AUTHOR), Hao, Yupei1 (AUTHOR), Wang, Ziyi (AUTHOR), Liu, Shuai (AUTHOR), Yuan, Shizhao (AUTHOR), Zhou, Chunhua1 (AUTHOR) zhouchunhua@hebmu.edu.cn, Yu, Jing1 (AUTHOR) yujing@hebmu.edu.cn

    المصدر: Journal of Affective Disorders. Feb2025, Vol. 370, p134-139. 6p.

    مصطلحات موضوعية: *CYTOCHROME P-450 CYP3A, *ORAL drug administration, *GENETIC variation, *LIVER failure, *GENETIC polymorphisms, *URIC acid


    أضف إلى المفضلة
  2. 2
    Academic Journal
    Drug-drug interactions of simnotrelvir/ritonavir: an open-label, fixed-sequence, two-period clinical trial.

    المؤلفون: Ye, Pan-Pan1 (AUTHOR), Yao, Bu-Fan1,2 (AUTHOR), Yang, Yang1,3,4 (AUTHOR), Yang, Xin-Mei1 (AUTHOR), Li, Qian1 (AUTHOR), Song, Lin-Lin1 (AUTHOR), Chen, Ke-Guang1 (AUTHOR), Zhou, Hai-Yan1 (AUTHOR), Shi, Jin-Yi1 (AUTHOR), Zhang, Ye-Hui1 (AUTHOR), Zhao, Fu-Rong1 (AUTHOR), Guo, Zi-jia3,5 (AUTHOR), Xu, Shan-sen3,5 (AUTHOR), Chen, Jia3,4 (AUTHOR), Goh, Aik Han3,5 (AUTHOR), Zhu, Shun-Wei3,5 (AUTHOR), Zheng, Yi1,2 (AUTHOR), Zhao, Wei1,2 (AUTHOR) zhao4wei2@hotmail.com

    المصدر: Clinical Microbiology & Infection. Jan2025, Vol. 31 Issue 1, p101-107. 7p.

    مصطلحات موضوعية: *CYTOCHROME P-450 CYP3A, *DRUG interactions, *BIOCHEMICAL substrates, *ITRACONAZOLE, *RITONAVIR, *PROTEASE inhibitors, *P-glycoprotein


    أضف إلى المفضلة
  3. 3
    Academic Journal
    Development of a physiologically‐based pharmacokinetic model for Ritonavir characterizing exposure and drug interaction potential at both acute and steady‐state conditions.

    المؤلفون: Ngo, Lien Thi1,2,3 (AUTHOR), Jung, Woojin1,4 (AUTHOR), Bui, Tham Thi1 (AUTHOR), Yun, Hwi‐yeol1,4,5 (AUTHOR) hyyun@cnu.ac.kr, Chae, Jung‐woo1,4,5,6 (AUTHOR) jmomper@health.ucsd.edu, Momper, Jeremiah D.6 (AUTHOR) jmomper@health.ucsd.edu

    المصدر: CPT: Pharmacometrics & Systems Pharmacology. Dec2024, p1. 17p. 3 Illustrations.

    مصطلحات موضوعية: *CYTOCHROME P-450 CYP3A, *DRUG interactions, *PARAMETER estimation, *SILDENAFIL, *PROTEASE inhibitors, *RITONAVIR, *CLARITHROMYCIN

    Full Text Finder

    أضف إلى المفضلة
  4. 4
    Academic Journal
    Effect of Itraconazole, a CYP3A4 Inhibitor, and Rifampin, a CYP3A4 Inducer, on the Pharmacokinetics of Vatiquinone.

    المؤلفون: Lee, Lucy1 (AUTHOR), Thoolen, Martin1 (AUTHOR), Ma, Jiyuan1 (AUTHOR), Kaushik, Diksha1 (AUTHOR), Golden, Lee1 (AUTHOR), Kong, Ronald1 (AUTHOR) rkong@ptcbio.com

    المصدر: Clinical Pharmacology in Drug Development. Dec2024, Vol. 13 Issue 12, p1283-1290. 8p.

    مصطلحات موضوعية: *CYTOCHROME P-450 CYP3A, *FRIEDREICH'S ataxia, *SMALL molecules, *RIFAMPIN, *ITRACONAZOLE, *RARE diseases


    أضف إلى المفضلة
  5. 5
    Academic Journal
    A carbamazepine metabolite activates NLRP3 and controls skin homing of CD8+ T-cells in SJS/TEN.

    المؤلفون: Zhang, Chen1 (AUTHOR), Qiao, Pei1 (AUTHOR), Zhang, JieYu1 (AUTHOR), Luo, YiXin1 (AUTHOR), Xiao, ChunYing1 (AUTHOR), Shen, ShengXian1 (AUTHOR), Hasegawa, Akio2 (AUTHOR), Qiao, HongJiang1 (AUTHOR), Wang, Gang1 (AUTHOR), Abe, Riichiro1,2 (AUTHOR) aberi@med.niigata-u.ac.jp, Fu, Meng1 (AUTHOR) 2239874942@qq.com

    المصدر: Journal of Dermatological Science. Dec2024, Vol. 116 Issue 3, p80-89. 10p.

    مصطلحات موضوعية: *CYTOTOXIC T cells, *CYTOCHROME P-450 CYP3A, *DRUG side effects, *TOXIC epidermal necrolysis, *ENZYME-linked immunosorbent assay


    أضف إلى المفضلة
  6. 6
    Academic Journal
    The preclinical pharmacokinetics of Tolinapant—A dual cIAP1/XIAP antagonist with in vivo efficacy.

    المؤلفون: Martins, Vanessa1 (AUTHOR), Ward, George1 (AUTHOR), Smyth, Tomoko1 (AUTHOR), Reader, Mike1 (AUTHOR), Chessari, Gianni1 (AUTHOR), Johnson, Chris1 (AUTHOR), Wilsher, Nicola1 (AUTHOR) nicola.wilsher@astx.com

    المصدر: Pharmacology Research & Perspectives. Dec2024, Vol. 12 Issue 6, p1-7. 7p.

    مصطلحات موضوعية: *SMALL molecules, *CYTOCHROME P-450 CYP3A, *LABORATORY mice, *CLINICAL trials, *MOIETIES (Chemistry)

    Full Text Finder

    أضف إلى المفضلة
  7. 7
    Academic Journal
    Heterotropic Activation of Cytochrome P450 3A4 by Perillyl Alcohol.

    المؤلفون: Ryu, Ji Hyeon1,2 (AUTHOR) jihyeon.ryu@kitox.re.kr, Yu, Jieun1 (AUTHOR) rhdwn0117@hanmail.net, Jeon, Jang Su1 (AUTHOR) navijang2@gmail.com, Jo, Seongyea2 (AUTHOR) hyeminkim@kitox.re.kr, Lee, Soo Min3 (AUTHOR) lsumin052@gmail.com, Kim, Hyemin2 (AUTHOR) hjpark@kitox.re.kr, Park, Han-Jin2 (AUTHOR), Oh, Soo Jin3 (AUTHOR) diatree@amc.seoul.kr, Kim, Sang Kyum1 (AUTHOR) diatree@amc.seoul.kr

    المصدر: Pharmaceutics. Dec2024, Vol. 16 Issue 12, p1581. 18p.

    مصطلحات موضوعية: *CYTOCHROME P-450 CYP3A, *LIQUID chromatography-mass spectrometry, *CYTOCHROME P-450, *PERILLA frutescens, *LIVER microsomes, *MONOTERPENES

    Full Text Finder

    أضف إلى المفضلة
  8. 8
    Academic Journal
    Pharmacokinetic Interaction Between Olaparib and Regorafenib in an Animal Model.

    المؤلفون: Szkutnik-Fiedler, Danuta1 (AUTHOR) akarbownik@ump.edu.pl, Karbownik, Agnieszka1 (AUTHOR) f.otto@ump.edu.pl, Otto, Filip1 (AUTHOR) grzesko@ump.edu.pl, Maciejewska, Julia2 (AUTHOR) julia.maciejewska1409@gmail.com, Kuźnik, Alicja2 (AUTHOR) alicjakuznik00@gmail.com, Grabowski, Tomasz3 (AUTHOR) tomasz.grabowski@gumed.edu.pl, Wolc, Anna4,5 (AUTHOR) awolc@iastate.edu, Grześkowiak, Edmund1 (AUTHOR) jstanislawiak@ump.edu.pl, Stanisławiak-Rudowicz, Joanna1,6 (AUTHOR) eszalek@ump.edu.pl, Szałek, Edyta1 (AUTHOR)

    المصدر: Pharmaceutics. Dec2024, Vol. 16 Issue 12, p1575. 19p.

    مصطلحات موضوعية: *CYTOCHROME P-450 CYP3A, *MEMBRANE transport proteins, *DRUG interactions, *LABORATORY rats, *BIOCHEMICAL substrates

    Full Text Finder

    أضف إلى المفضلة
  9. 9
    Academic Journal
    Population pharmacokinetic analysis of quizartinib in patients with newly diagnosed FLT3‐internal‐tandem‐duplication‐positive acute myeloid leukemia.

    المؤلفون: Vaddady, Pavan1 (AUTHOR), Glatard, Anaïs2 (AUTHOR), Smania, Giovanni2 (AUTHOR), Nakayama, Shintaro3 (AUTHOR), Inoue, Hiroyuki3 (AUTHOR), Kurumaddali, Abhinav1 (AUTHOR), Abutarif, Malaz1 (AUTHOR), Zheng, Ming1 (AUTHOR) ming.zheng@daiichisankyo.com

    المصدر: CTS: Clinical & Translational Science. Dec2024, Vol. 17 Issue 12, p1-17. 17p.

    مصطلحات موضوعية: *CYTOCHROME P-450 CYP3A, *ACUTE myeloid leukemia, *CLINICAL trials, *CONSOLIDATION chemotherapy, *INDUCTION chemotherapy, *PHARMACOKINETICS

    Full Text Finder

    أضف إلى المفضلة
  10. 10
    Academic Journal
    Deconvoluting zavegepant drug–drug interactions: A phase I study to evaluate the effects of rifampin and itraconazole on zavegepant pharmacokinetics.

    المؤلفون: Bhardwaj, Rajinder1 (AUTHOR), Malatesta, Jo Ann1 (AUTHOR), Madonia, Jennifer2 (AUTHOR), Anderson, Matt S.1 (AUTHOR), Morris, Beth2 (AUTHOR), Matschke, Kyle T.3 (AUTHOR), Croop, Robert2 (AUTHOR), Bertz, Richard2 (AUTHOR), Liu, Jing4 (AUTHOR) jing.liu@pfizer.com

    المصدر: CTS: Clinical & Translational Science. Dec2024, Vol. 17 Issue 12, p1-12. 12p.

    مصطلحات موضوعية: *CYTOCHROME P-450 CYP3A, *INTRANASAL medication, *PEPTIDE receptors, *ITRACONAZOLE, *ORGANIC anion transporters, *RIFAMPIN, *SUMATRIPTAN

    Full Text Finder

    أضف إلى المفضلة
  11. 11
    Academic Journal
    The augment effects of magnesium hydride on the lipid lowering effect of atorvastatin: an in vivo and in vitro investigation.

    المؤلفون: Chen, Wanqiu1 (AUTHOR), Zhang, Yinyin2 (AUTHOR), Miao, Gen2 (AUTHOR), Ying, Yajing2 (AUTHOR), Ren, Zifu2 (AUTHOR), Sun, Xuejun2,3 (AUTHOR), Cai, Jianming1,2 (AUTHOR) cjm882003@163.com, Shen, Hui2 (AUTHOR) shenhuicn@126.com, Lu, Hongtao2 (AUTHOR) hongtao_lu1990@163.com

    المصدر: Medical Gas Research. Mar2025, Vol. 15 Issue 1, p148-155. 8p.

    مصطلحات موضوعية: *CYTOCHROME P-450 CYP3A, *PEROXISOME proliferator-activated receptors, *BLOOD lipids, *MAGNESIUM hydride, *BLOOD cholesterol

    Full Text Finder

    أضف إلى المفضلة
  12. 12
    Academic Journal
    The Effect of Metformin and Hydrochlorothiazide on Cytochrome P450 3A4 Metabolism of Ivermectin: Insights from In Silico Experimentation.

    المؤلفون: Mtambo, Thuli R.1,2 (AUTHOR), Machaba, Kgothatso E.1,3 (AUTHOR), Chellan, Nireshni2,4 (AUTHOR), Ramharack, Pritika2 (AUTHOR), Muller, Christo J. F.2,4 (AUTHOR), Mhlongo, Ndumiso N.3 (AUTHOR), Hlengwa, Nokulunga1 (AUTHOR) hlengwan@unizulu.ac.za

    المصدر: International Journal of Molecular Sciences. Nov2024, Vol. 25 Issue 22, p12089. 13p.

    مصطلحات موضوعية: *CYTOCHROME P-450 CYP3A, *IVERMECTIN, *ROOT-mean-squares, *PRINCIPAL components analysis, *ANTIPARASITIC agents, *HYDROCHLOROTHIAZIDE, *METFORMIN

    Full Text Finder

    أضف إلى المفضلة
  13. 13
    Academic Journal
    Development of novel CDK9 and CYP3A4 inhibitors for cancer therapy through field and computational approaches.

    المؤلفون: Alsfouk, Aisha A.1 (AUTHOR) aaalsfouk@pnu.edu.sa, Faris, Abdelmoujoud2 (AUTHOR) aaalsfouk@pnu.edu.sa, Cacciatore, Ivana3 (AUTHOR), Alnajjar, Radwan4 (AUTHOR)

    المصدر: Frontiers in Chemistry. 2024, p1-17. 17p.

    مصطلحات موضوعية: *CYTOCHROME P-450 CYP3A, *MOLECULAR dynamics, *MOLECULAR conformation, *DRUG metabolism, *DRUG design

    Full Text Finder

    أضف إلى المفضلة
  14. 14
    Academic Journal
    Concentration–QT modeling demonstrates that the selective mineralocorticoid receptor modulator, balcinrenone (AZD9977), does not prolong QT interval.

    المؤلفون: Sundell, Jesper1,2 (AUTHOR), Rekic, Dinko1,3 (AUTHOR), Melin, Johanna1 (AUTHOR), Johansson, Susanne1 (AUTHOR), Ebrahimi, Ahmad4 (AUTHOR), Dota, Corina4 (AUTHOR), Parkinson, Joanna1 (AUTHOR) joanna.parkinson@astrazeneca.com

    المصدر: CPT: Pharmacometrics & Systems Pharmacology. Nov2024, p1. 10p. 4 Illustrations.

    مصطلحات موضوعية: *CYTOCHROME P-450 CYP3A, *MINERALOCORTICOID receptors, *CHRONIC kidney failure, *KIDNEY physiology, *HEART failure

    Full Text Finder

    أضف إلى المفضلة
  15. 15
    Academic Journal
    Generation and application of CES1-knockout Tet-Off-regulated CYP3A4 and UGT1A1-expressing Caco-2 cells.

    المؤلفون: Murata, Michika1 (AUTHOR), Okada, Kentaro2,3 (AUTHOR), Takahashi, Masaki4 (AUTHOR), Ueyama-Toba, Yukiko1,3,5 (AUTHOR), Ito, Sumito4 (AUTHOR), Mizuguchi, Hiroyuki1,2,3,5,6,7 (AUTHOR) mizuguch@phs.osaka-u.ac.jp

    المصدر: Toxicology Letters. Nov2024, Vol. 401, p158-169. 12p.

    مصطلحات موضوعية: *CYTOCHROME P-450 CYP3A, *URIDINE diphosphate, *CELL metabolism, *DRUG absorption, *SMALL intestine


    أضف إلى المفضلة
  16. 16
    Academic Journal
    Pharmacometrics in obstetrics and maternal–fetal medicine research: Bridging gaps in maternal and fetal pharmacology.

    المؤلفون: Eke, Ahizechukwu C.1 (AUTHOR) aeke2@jhu.edu, Adams, Emily2 (AUTHOR), Eleje, George U.3 (AUTHOR), Ezebialu, Ifeanyichukwu U.4 (AUTHOR), Aliyu, Muktar H.5 (AUTHOR)

    المصدر: CPT: Pharmacometrics & Systems Pharmacology. Nov2024, Vol. 13 Issue 11, p1835-1840. 6p.

    مصطلحات موضوعية: *PRENATAL drug exposure, *CYTOCHROME P-450 CYP3A, *PHARMACOGENOMICS, *OBSTETRICS, *DRUG absorption, *HIV-positive women, *PREGNANCY, *MULTIPLE pregnancy

    Full Text Finder

    أضف إلى المفضلة
  17. 17
    Academic Journal
    Concentration‐QTcF analysis of quizartinib in patients with newly diagnosed FLT3‐internal‐tandem‐duplication‐positive acute myeloid leukemia.

    المؤلفون: Vaddady, Pavan1 (AUTHOR), Smania, Giovanni2 (AUTHOR), Nakayama, Shintaro3 (AUTHOR), Inoue, Hiroyuki3 (AUTHOR), Kurumaddali, Abhinav1 (AUTHOR), Abutarif, Malaz1 (AUTHOR), Zheng, Ming1 (AUTHOR) ming.zheng@daiichisankyo.com

    المصدر: CTS: Clinical & Translational Science. Nov2024, Vol. 17 Issue 11, p1-12. 12p.

    مصطلحات موضوعية: *CYTOCHROME P-450 CYP3A, *ACUTE myeloid leukemia, *CLINICAL trials, *PHARMACODYNAMICS, *CONFIDENCE intervals

    Full Text Finder

    أضف إلى المفضلة
  18. 18
    Academic Journal
    Predicting Food–Drug Interactions between Piperine and CYP3A4 Substrate Drugs Using PBPK Modeling.

    المؤلفون: Lin, Feifei1,2 (AUTHOR) feifei.lin@simm.ac.cn, Hu, Yingchun2 (AUTHOR), Zhang, Yifan2 (AUTHOR), Zhao, Lijuan2 (AUTHOR), Zhong, Dafang2 (AUTHOR), Liu, Jia1,2 (AUTHOR) jia.liu@simm.ac.cn

    المصدر: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 20, p10955. 13p.

    مصطلحات موضوعية: *CYTOCHROME P-450, *CYTOCHROME P-450 CYP3A, *NIFEDIPINE, *CYCLOSPORINE, *RITONAVIR

    Full Text Finder

    أضف إلى المفضلة
  19. 19
    Academic Journal
    Physiologically based pharmacokinetic modelling to predict potential drug–drug interactions of dersimelagon (MT‐7117)

    المؤلفون: Ogasawara, Akihito1 (AUTHOR) ogasawara.akihito@mm.mt-pharma.co.jp, Kojima, Koki1 (AUTHOR), Murata, Yukiko1 (AUTHOR), Shimizu, Hidetoshi1 (AUTHOR)

    المصدر: British Journal of Clinical Pharmacology. Oct2024, p1. 13p. 5 Illustrations.

    مصطلحات موضوعية: *CYTOCHROME P-450 CYP3A, *BIOCHEMICAL substrates, *CYTOCHROME P-450, *DRUG interactions, *ATORVASTATIN, *ORGANIC anion transporters

    Full Text Finder

    أضف إلى المفضلة
  20. 20
    Academic Journal
    Absorption, Metabolism, and Excretion of [14C]‐Labeled Anaprazole: A New Proton Pump Inhibitor, After a Single Oral Administration in Healthy Chinese Male Subjects.

    المؤلفون: Xie, Lijun1 (AUTHOR), Xu, Yanjun2 (AUTHOR), Liu, Wei3 (AUTHOR), Zhou, Chen1 (AUTHOR), Guo, Lian4 (AUTHOR), Zhou, Sufeng1 (AUTHOR), Zhang, Chen3 (AUTHOR), Chen, Juan1 (AUTHOR), Zhu, Bei1 (AUTHOR), Ding, Sijia1 (AUTHOR), Li, Huan4 (AUTHOR), Zhang, Lingling4 (AUTHOR), Wang, Li2 (AUTHOR), Xu, Lingmei2 (AUTHOR), Shao, Feng1 (AUTHOR), Wang, Lu1 (AUTHOR) wanglu2333@163.com

    المصدر: Clinical Pharmacology in Drug Development. Oct2024, Vol. 13 Issue 10, p1115-1122. 8p.

    مصطلحات موضوعية: *CYTOCHROME P-450 CYP3A, *ORAL drug administration, *PROTON pump inhibitors, *HUMAN body, *CARBOXYLIC acids


    أضف إلى المفضلة
أدوات البحث: أحصل على تغذية RSS – أرسل هذا البحث بالبريد الإلكتروني – حفظ البحث – جدول التنبيهات: لا شيء