المؤلفون: Kunpeng Huang, Changyan Wang, Bosheng Mei, Jinglei Li, Tianxing Ren, Hanjing Zhan, Yunwei Zhang, Bowen Zhang, Xinyu Lv, Qi Zhang, Yong Guan, Xiaofei Zhang, Guoliang Wang, Wenming Pan, Peng Xu, Hui Wang, Jinxiang Zhang

المصدر: JHEP Reports, Vol 6, Iss 8, Pp 101101- (2024)

مصطلحات موضوعية: S1PR2, Pyroptosis, CYP2C70, GSDMD, Liver transplantation, Macrophages, Diseases of the digestive system. Gastroenterology, RC799-869

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555924001058; https://doaj.org/toc/2589-5559

URL الوصول: https://doaj.org/article/24b0a74732b7478aa5c3e5f33c355d5f

المؤلفون: Mohammad Nazmul Hasan, Jianglei Chen, David Matye, Huaiwen Wang, Wenyi Luo, Lijie Gu, Yung Dai Clayton, Yanhong Du, Tiangang Li

المصدر: Journal of Lipid Research, Vol 64, Iss 3, Pp 100340- (2023)

مصطلحات موضوعية: bile acid, ASBT, CYP7A1, FXR, cholestasis, CYP2C70, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227523000135; https://doaj.org/toc/0022-2275

URL الوصول: https://doaj.org/article/897440a21bd44797a0f914ca459f29f9

المؤلفون: Teruo Miyazaki, Hajime Ueda, Tadashi Ikegami, Akira Honda

المصدر: Metabolites; Volume 13; Issue 7; Pages: 824

مصطلحات موضوعية: taurine synthesis, bile acid conjugation, FXR, Bacs, Baat, Cdo, Fmo1, mouse model with human-like BA composition, Cyp2a12 −/− / Cyp2c70 −/−

وصف الملف: application/pdf

Relation: Nutrition and Metabolism; https://dx.doi.org/10.3390/metabo13070824

الاتاحة: https://doi.org/10.3390/metabo13070824

المؤلفون: Mohammad Nazmul Hasan, Jianglei Chen, Huaiwen Wang, Yanhong Du, Yung Dai Clayton, Lijie Gu, Tiangang Li

المصدر: Cells; Volume 12; Issue 10; Pages: 1371

مصطلحات موضوعية: bile acid, ASBT, CYP7A1, FXR, cholestasis, CYP2C70

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/cells12101371

الاتاحة: https://doi.org/10.3390/cells12101371

المؤلفون: Sjöland, Wilhelm, Wahlström, Annika, Makki, Kassem, Schöler, Marc, Molinaro, Antonio, Olsson, Lisa, Greiner, Thomas Uwe, Caesar, Robert, de Boer, Jan Freark, Kuipers, Folkert, Bäckhed, Fredrik, Marschall, Hanns Ulrich

المصدر: Sjöland , W , Wahlström , A , Makki , K , Schöler , M , Molinaro , A , Olsson , L , Greiner , T U , Caesar , R , de Boer , J F , Kuipers , F , Bäckhed , F & Marschall , H U 2023 , ' Absence of gut microbiota reduces neonatal survival and exacerbates liver disease in Cyp2c70 -deficient mice with a human-like bile acid composition ' , Clinical Science , vol. 137 , no. 13 , pp. 995-1011 . https://doi.org/10.1042/CS20230413

مصطلحات موضوعية: bile acids, cyp2c70, faecal microbiota transplantation, gut microbiota, hepatobiliary disease, ursodeoxycholic acid

وصف الملف: application/pdf

الاتاحة: https://curis.ku.dk/portal/da/publications/absence-of-gut-microbiota-reduces-neonatal-survival-and-exacerbates-liver-disease-in-cyp2c70deficient-mice-with-a-humanlike-bile-acid-composition(5dbd4711-e228-499f-b616-3664a6f8dd57).html
https://doi.org/10.1042/CS20230413
https://curis.ku.dk/ws/files/360979599/cs_2023_0413_1.pdf

المؤلفون: Sara Straniero, Amit Laskar, Christina Savva, Jennifer Härdfeldt, Bo Angelin, Mats Rudling

المصدر: Journal of Lipid Research, Vol 61, Iss 4, Pp 480-491 (2020)

مصطلحات موضوعية: cholesterol/metabolism, low density lipoprotein/metabolism, bile acids and salts/metabolism, Cyp2c70, lipoproteins, cholestasis, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520434996; https://doaj.org/toc/0022-2275

URL الوصول: https://doaj.org/article/da249c4ad2704e6e8aa69b69b72474f2

المؤلفون: Akira Honda, Teruo Miyazaki, Junichi Iwamoto, Takeshi Hirayama, Yukio Morishita, Tadakuni Monma, Hajime Ueda, Seiya Mizuno, Fumihiro Sugiyama, Satoru Takahashi, Tadashi Ikegami

المصدر: Journal of Lipid Research, Vol 61, Iss 1, Pp 54-69 (2020)

مصطلحات موضوعية: CRISPR-Cas9, cytochrome P450, CYP2A12, CYP2C70, cholesterol 7α-hydroxylase, 7α-hydroxy-4-cholesten-3-one 12α-hydroxylase, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S002222752030016X; https://doaj.org/toc/0022-2275

URL الوصول: https://doaj.org/article/b6ca2ce2cff4472a9322001da895e681

المؤلفون: Rumei Li, Anna Palmiotti, Hilde D. de Vries, Milaine V. Hovingh, Martijn Koehorst, Niels L. Mulder, Yue Zhang, Kim Kats, Vincent W. Bloks, Jingyuan Fu, Henkjan J. Verkade, Jan Freark de Boer, Folkert Kuipers

المصدر: Journal of Lipid Research, Vol 62, Iss , Pp 100134- (2021)

مصطلحات موضوعية: bile acids, Cyp2c70, Cyp8b1, fat absorption, obesity, fatty liver disease, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227521001164; https://doaj.org/toc/0022-2275

URL الوصول: https://doaj.org/article/f8cb60c473764338b6419affd52446ef

المؤلفون: Shogo Takahashi, Tatsuki Fukami, Yusuke Masuo, Chad N. Brocker, Cen Xie, Kristopher W. Krausz, C. Roland Wolf, Colin J. Henderson, Frank J. Gonzalez

المصدر: Journal of Lipid Research, Vol 57, Iss 12, Pp 2130-2137 (2016)

مصطلحات موضوعية: chenodeoxycholic acid, cytochrome P450, Cyp2c70, enzyme kinetics, liver, muricholic acid, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520345399; https://doaj.org/toc/0022-2275

URL الوصول: https://doaj.org/article/b492e5b921554905ba4d7d1bcb88606c

المؤلفون: Michael Goedken, Grace L. Guo, Brian Buckley, Bo Kong, Anita M. Brinker, Rulaiha Elizabeth Taylor, Daniel Rizzolo

المصدر: Acta Pharmaceutica Sinica B, Vol 11, Iss 12, Pp 3847-3856 (2021)
Acta Pharmaceutica Sinica. B

مصطلحات موضوعية: DKO, double knockout, WT, wild type, CYP7A1, CYP8B1, sterol 12α-hydroxylase, NTCP, sodium taurocholate cotransporting polypeptide, ASBT, apical sodium-dependent BA transporter, IBABP, intestinal BA-binding protein, 0302 clinical medicine, βMCA, beta muricholic acid, AST, aspartate transaminase, CYP27A1, General Pharmacology, Toxicology and Pharmaceutics, Receptor, LCA, lithocholic acid, 0303 health sciences, CA, cholic acid, Bile acid, Chemistry, OATP, organic anion transporters, Fibroblast growth factor 15, OSTα/β, organic solute transporters alpha and beta, medicine.anatomical_structure, 030220 oncology & carcinogenesis, BA, bile acid, Original Article, Female, Cholestasis of pregnancy, medicine.medical_specialty, medicine.drug_class, RM1-950, Cholesterol 7 alpha-hydroxylase, CDCA, chenodeoxycholic acid, 03 medical and health sciences, FXR, farnesoid X receptor, Farnesoid X receptor, CYP27A1, sterol 27-hydroxylase, Internal medicine, ALT, alanine aminotransferase, medicine, BSEP, bile salt export pump, 030304 developmental biology, ALP, alkaline phosphatase, medicine.disease, CYP7A1, cholesterol 7α-hydroxylase, Small intestine, Bile acids, Endocrinology, Nuclear receptor, DCA, deoxycholic acid, CYP7B1, 25-hydroxycholesterol 7-alpha-hydroxylase, Therapeutics. Pharmacology, CYP2C70, cytochrome P450 2C70

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3528a74d648335c5d6495523367f011
http://www.sciencedirect.com/science/article/pii/S2211383521001891

المؤلفون: Teruo Miyazaki, Tadashi Ikegami, Satoru Takahashi, Junichi Iwamoto, Tadakuni Monma, Fumihiro Sugiyama, Akira Honda, Yukio Morishita, Seiya Mizuno, Takeshi Hirayama, Hajime Ueda

المصدر: Journal of Lipid Research, Vol 61, Iss 1, Pp 54-69 (2020)
J Lipid Res

مصطلحات موضوعية: Male, 0301 basic medicine, Lithocholic acid, cytochrome P450, medicine.drug_class, QD415-436, 030204 cardiovascular system & hematology, Chenodeoxycholic Acid, Biochemistry, Bile Acids and Salts, Rats, Sprague-Dawley, CYP2A12, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Cytochrome P-450 Enzyme System, Chenodeoxycholic acid, 7α-hydroxy-4-cholesten-3-one 12α-hydroxylase, medicine, Animals, Research Articles, Mice, Knockout, Molecular Structure, cholesterol 7α-hydroxylase, Bile acid, Deoxycholic acid, Cholic acid, CYP2C70, Cell Biology, Molecular biology, Rats, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, chemistry, Steroid Hydroxylases, Knockout mouse, Small heterodimer partner, Female, Farnesoid X receptor, Aryl Hydrocarbon Hydroxylases, CRISPR-Cas9, Hydrophobic and Hydrophilic Interactions

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0208c867d823ecf4443ddb865a56abc8
https://doi.org/10.1194/jlr.ra119000395

المؤلفون: Rumei Li, Yue Zhang, Hilde D. de Vries, Folkert Kuipers, Vincent W. Bloks, Martijn Koehorst, Henkjan J. Verkade, Niels L. Mulder, Kim Kats, Jingyuan Fu, Anna Palmiotti, Milaine V. Hovingh, Jan Freark de Boer

المساهمون: Health & Food, Center for Liver, Digestive and Metabolic Diseases (CLDM), Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI)

المصدر: Journal of Lipid Research, Vol 62, Iss, Pp 100134-(2021)
Journal of lipid research
Journal of Lipid Research, 62:100134. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC

مصطلحات موضوعية: medicine.medical_specialty, obesity, humanized mouse model, medicine.drug_class, Muricholic acid, INTESTINAL-ABSORPTION, QD415-436, METABOLISM, Biochemistry, Intestinal absorption, chemistry.chemical_compound, Endocrinology, Internal medicine, Chenodeoxycholic acid, REVEALS, medicine, GUT, chemistry.chemical_classification, bile acids, CYP8B1, Bile acid, Fatty liver, Fatty acid, Cell Biology, fat absorption, Cyp2c70, medicine.disease, CHOLESTEROL ABSORPTION, MICROBIOTA, TRANSPORT, RECEPTORS, chemistry, fatty liver disease, Steatosis, RESISTANCE

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb89195bca8046ffccc15b4343e2c120
https://hdl.handle.net/11370/e1523a7e-9c97-4134-9a34-c2442f88fe3c

المؤلفون: Jennifer Härdfeldt, Bo Angelin, Amit Laskar, Sara Straniero, Christina Savva, Mats Rudling

المصدر: J Lipid Res
Journal of Lipid Research, Vol 61, Iss 4, Pp 480-491 (2020)

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, medicine.drug_class, cholesterol/metabolism, QD415-436, 030204 cardiovascular system & hematology, Fibroblast growth factor, Biochemistry, Bile Acids and Salts, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Endocrinology, Cholestasis, Species Specificity, Internal medicine, medicine, Animals, Humans, Research Articles, Bile acid, Cholesterol, bile acids and salts/metabolism, Cholic Acids, Cell Biology, Metabolism, Cyp2c70, low density lipoprotein/metabolism, medicine.disease, Phenotype, lipoproteins, 030104 developmental biology, chemistry, Liver, LDL receptor, Liver function, cholestasis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::936b122662189ded67b97fb54ef1070b
https://pubmed.ncbi.nlm.nih.gov/32086245

المؤلفون: C. Roland Wolf, Kristopher W. Krausz, Colin J. Henderson, Cen Xie, Shogo Takahashi, Frank J. Gonzalez, Chad Brocker, Yusuke Masuo, Tatsuki Fukami

المصدر: Journal of Lipid Research, Vol 57, Iss 12, Pp 2130-2137 (2016)

مصطلحات موضوعية: 0301 basic medicine, Male, Taurine, medicine.drug_class, cytochrome P450, animal diseases, Muricholic acid, Gene Expression, QD415-436, liver, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Cytochrome P-450 Enzyme System, Species Specificity, Chenodeoxycholic acid, enzyme kinetics, medicine, Animals, Humans, cardiovascular diseases, Research Articles, Mice, Knockout, biology, Bile acid, Cholic acid, Cytochrome P450, Cholic Acids, muricholic acid, Cell Biology, Hep G2 Cells, Cyp2c70, Ursodeoxycholic acid, nervous system diseases, Mice, Inbred C57BL, Kinetics, 030104 developmental biology, chemistry, biology.protein, cardiovascular system, 030211 gastroenterology & hepatology, Farnesoid X receptor, chenodeoxycholic acid, Oxidation-Reduction, medicine.drug, circulatory and respiratory physiology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7b203bbbe1d74a035e7b0b109d7fdca
http://www.sciencedirect.com/science/article/pii/S0022227520345399

المؤلفون: Takahashi, Shogo, Fukami, Tatsuki, Masuo, Yusuke, Brocker, Chad N., Xie, Cen, Krausz, Kristopher W., Wolf, C. Roland, Henderson, Colin J., Gonzalez, Frank J.

المصدر: Takahashi , S , Fukami , T , Masuo , Y , Brocker , C N , Xie , C , Krausz , K W , Wolf , C R , Henderson , C J & Gonzalez , F J 2016 , ' Cyp2c70 is responsible for the species difference in bile acid metabolism between mice and humans ' Journal of Lipid Research , vol 57 , pp. 2130-2037 . DOI:10.1194/jlr.M071183

مصطلحات موضوعية: chenodeoxycholic acid, cytochrome P450, Cyp2c70, enzyme kinetics, liver, muricholic acid, ursodeoxycholic acid, socio, envir

Relation: http://discovery.dundee.ac.uk/ws/files/10346883/J._Lipid_Res._2016_Takahashi_jlr.M071183.pdf; http://discovery.dundee.ac.uk/portal/en/research/cyp2c70-is-responsible-for-the-species-difference-in-bile-acid-metabolism-between-mice-and-humans(cb190a00-16fc-4b98-81dc-51fdb0952e1c).html

الاتاحة: http://discovery.dundee.ac.uk/ws/files/10346883/J._Lipid_Res._2016_Takahashi_jlr.M071183.pdf
http://discovery.dundee.ac.uk/portal/en/research/cyp2c70-is-responsible-for-the-species-difference-in-bile-acid-metabolism-between-mice-and-humans(cb190a00-16fc-4b98-81dc-51fdb0952e1c).html

المؤلفون: Guinot, Valentine

المساهمون: Université de Lille (2022-.), Dombrowicz, David

مصطلحات موضوعية: Acides Biliaires, Immunité hépatique, Souris, Cyp2c70, Récepteurs aux acides biliaires, Bile acids, Hepatic immunity, Mice, Bile acids receptors

Relation: http://www.theses.fr/2022ULILS060

الاتاحة: http://www.theses.fr/2022ULILS060