المؤلفون: N. A. Avxentyev, I. I. Andreyashkina, E. V. Artamonova, L. V. Bolotina, E. I. Kovalenko, N. N. Sisigina

المصدر: Опухоли женской репродуктивной системы, Vol 20, Iss 1, Pp 64-81 (2024)

مصطلحات موضوعية: breast cancer, cyclin-dependent kinase 4 and 6 inhibitors, abemaciclib, palbociclib, ribociclib, Gynecology and obstetrics, RG1-991

وصف الملف: electronic resource

Relation: https://ojrs.abvpress.ru/ojrs/article/view/1209; https://doaj.org/toc/1994-4098; https://doaj.org/toc/1999-8627

URL الوصول: https://doaj.org/article/7c741cff50634683809ceae6e0a09add

المؤلفون: Gomes, Inês Fernandes

المساهمون: Casimiro, Sandra Cristina Cara de Anjo, Costa, Luís António Marques da, Repositório da Universidade de Lisboa

مصطلحات موضوعية: cancro da mama (CM), resistência à terapia, via de sinalização do recetor ativador do fator nuclear-kB (RANK), inibidores de cinases dependentes de ciclina 4 e 6 (iCDK4/6), inibidores do ligando do RANK (iRANKL), breast cancer (BC), therapy resistance, receptor activator of nuclear factor-kB (RANK) signaling pathway, cyclin dependent kinase 4 and 6 inhibitors (CDK4/6i), RANK ligand inhibitors (RANKLi), Domínio/Área Científica::Ciências Médicas::Ciências da Saúde

وصف الملف: application/pdf

الاتاحة: http://hdl.handle.net/10451/64865

المؤلفون: XueFeng, Guan, Pavani, Krishna Chaitanya, Chunduru, Jayendra, Broeckx, Bart, Van Soom, Ann, Peelman, Luc

المصدر: CANCERS ; ISSN: 2072-6694

مصطلحات موضوعية: Medicine and Health Sciences, Veterinary Sciences, Cancer Research, Oncology, therapeutic strategies, breast cancer (BC), cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6i), tumorigenesis, biomarker, cancer, Hsa-miR-665

وصف الملف: application/pdf

Relation: https://biblio.ugent.be/publication/01HCFHDV0FSFA66J44QXPMPB58; http://doi.org/10.3390/cancers15204915; https://biblio.ugent.be/publication/01HCFHDV0FSFA66J44QXPMPB58/file/01HCFHF1DF66CVS7YVKYWJ13N2

الاتاحة: https://biblio.ugent.be/publication/01HCFHDV0FSFA66J44QXPMPB58
http://hdl.handle.net/1854/LU-01HCFHDV0FSFA66J44QXPMPB58
https://doi.org/10.3390/cancers15204915
https://biblio.ugent.be/publication/01HCFHDV0FSFA66J44QXPMPB58/file/01HCFHF1DF66CVS7YVKYWJ13N2

المؤلفون: Inês Gomes, Catarina Abreu, Luis Costa, Sandra Casimiro

المصدر: Cancers, Vol 15, Iss 4835, p 4835 (2023)

مصطلحات موضوعية: cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6i), breast cancer (BC), therapeutic strategies, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

Relation: https://www.mdpi.com/2072-6694/15/19/4835; https://doaj.org/toc/2072-6694; https://doaj.org/article/e5de99e8506e4c228f7d1f4da85768a8

الاتاحة: https://doi.org/10.3390/cancers15194835
https://doaj.org/article/e5de99e8506e4c228f7d1f4da85768a8

المؤلفون: Hamilton, Erika, Cortes, Javier, Ozyilkan, Ozgur, Chen, Shin-Cheh, Petrakova, Katarina, Manikhas, Aleksey, Jerusalem, Guy, Hegg, Roberto, Huober, Jens, Zhang, Wei, Chen, Yanyun, Martin, Miguel

المصدر: Breast Cancer Research and Treatment, 195 (1), 55 - 64 (2022-08)

مصطلحات موضوعية: Cyclin-dependent kinase 4 and 6, Endocrine therapy, HER2-negative, Hormone receptor-positive, MBC, Overall survival, Aminopyridines, Benzimidazoles, Tamoxifen, abemaciclib, Female, Humans, Progression-Free Survival, Tamoxifen/therapeutic use, Aminopyridines/adverse effects, Antineoplastic Combined Chemotherapy Protocols/adverse effects, Benzimidazoles/adverse effects, Breast Neoplasms/drug therapy, Breast Neoplasms/pathology, Antineoplastic Combined Chemotherapy Protocols, Breast Neoplasms, Receptor, ErbB-2, Oncology, Cancer Research, Human health sciences, Sciences de la santé humaine, Oncologie

Relation: https://link.springer.com/content/pdf/10.1007/s10549-022-06662-9.pdf; urn:issn:0167-6806; urn:issn:1573-7217

URL الوصول: https://orbi.uliege.be/handle/2268/300155

المؤلفون: Konecny, Gottfried E

المصدر: Current Opinion in Obstetrics & Gynecology. 28(1)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Brain Cancer, Brain Disorders, Orphan Drug, Breast Cancer, Rare Diseases, Ovarian Cancer, Cancer, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Aminopyridines, Antineoplastic Agents, Antineoplastic Combined Chemotherapy Protocols, Breast Neoplasms, Cell Cycle, Cyclin-Dependent Kinase 4, Cyclin-Dependent Kinase 6, Female, Humans, Liposarcoma, Lymphoma, Mantle-Cell, Melanoma, Neoplasms, Germ Cell and Embryonal, Piperazines, Protein Kinase Inhibitors, Purines, Pyridines, Signal Transduction, abemaciclib (LY2835219) and ribociclib, cyclin-dependent kinase 4 and 6 inhibition, palbociclib, Paediatrics and Reproductive Medicine, Obstetrics & Reproductive Medicine, Reproductive medicine

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/25w1d4f4

المؤلفون: I. B. Kononenko, A. V. Snegovoi, V. Yu. Selchuk

المصدر: Медицинский совет, Vol 0, Iss 10, Pp 42-55 (2019)

مصطلحات موضوعية: metastatic breast cancer, cyclin-dependent kinases, cyclin-dependent kinase 4 and 6 inhibitors, efficiency, side effects, Medicine

وصف الملف: electronic resource

Relation: https://www.med-sovet.pro/jour/article/view/3052; https://doaj.org/toc/2079-701X; https://doaj.org/toc/2658-5790

URL الوصول: https://doaj.org/article/b517f2cb29b8438eb60f79427d71d2d0

المؤلفون: Inoue, Kenichi, Masuda, Norikazu, Iwata, Hiroji, Takahashi, Masato, Ito, Yoshinori, Miyoshi, Yasuo, Nakayama, Takahiro, Mukai, Hirofumi, van der Walt, Jan-Stefan, Mori, Joji, Sakaguchi, Sachi, Kawaguchi, Tsutomu, Tanizawa, Yoshinori, Llombart-Cussac, Antonio, Sledge, George W., Toi, Masakazu

المساهمون: 戸井, 雅和, 10207516

مصطلحات موضوعية: Abemaciclib, Breast cancer, Cyclin-dependent kinase 4 and 6 inhibitor

Relation: http://hdl.handle.net/2433/277491; Breast Cancer; 28; 1038; 1050

الاتاحة: http://hdl.handle.net/2433/277491

المؤلفون: Dominika Tempka, Paulina Tokarz, Kinga Chmielewska, Magdalena Kluska, Julita Pietrzak, Żaneta Rygielska, László Virág, Agnieszka Robaszkiewicz

المصدر: Redox Biology, Vol 15, Iss C, Pp 316-326 (2018)

مصطلحات موضوعية: Cyclin-dependent kinase 4 and 6 (iCDK4/6), Poly(ADP-ribose) polymerase 1 (PARP1), 8-oxoguanine glycosylase (OGG1), Reactive oxygen species (ROS), Medicine (General), R5-920, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231717308960; https://doaj.org/toc/2213-2317

URL الوصول: https://doaj.org/article/88283f2ff72d437997827ae8c1faa1c1

المؤلفون: Rocca, Andrea, Melegari, Elisabetta, Palleschi, Michela

المساهمون: Rocca, Andrea, Melegari, Elisabetta, Palleschi, Michela

مصطلحات موضوعية: advanced breast cancer, luminal, cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitor, ribociclib, palbociclib

Relation: info:eu-repo/semantics/altIdentifier/pmid/31618549; info:eu-repo/semantics/altIdentifier/wos/WOS:000491085100017; volume:381; issue:16; firstpage:1592; lastpage:1593; numberofpages:2; journal:THE NEW ENGLAND JOURNAL OF MEDICINE; https://hdl.handle.net/11368/3040180; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85073448819

الاتاحة: https://hdl.handle.net/11368/3040180
https://doi.org/10.1056/NEJMc1911188
https://www.nejm.org/doi/10.1056/NEJMc1911188

المؤلفون: Sobhani N., D'Angelo A., Pittacolo M., Roviello G., Miccoli A., Corona S. P., Bernocchi O., Generali D., Otto T.

المساهمون: Sobhani, N., D'Angelo, A., Pittacolo, M., Roviello, G., Miccoli, A., Corona, S. P., Bernocchi, O., Generali, D., Otto, T.

مصطلحات موضوعية: breast cancer, cyclin-dependent kinase 4 and 6 inhibitor, cyclin-dependent kinase, targeted therapies

وصف الملف: ELETTRONICO

Relation: info:eu-repo/semantics/altIdentifier/pmid/30959874; info:eu-repo/semantics/altIdentifier/wos/WOS:000467304300035; volume:8; issue:4; firstpage:"-"; lastpage:"-"; numberofpages:24; journal:CELLS; https://hdl.handle.net/11368/3053139; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85067212188; https://www.mdpi.com/2073-4409/8/4/321; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523967/

الاتاحة: https://hdl.handle.net/11368/3053139
https://doi.org/10.3390/cells8040321
https://www.mdpi.com/2073-4409/8/4/321
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523967/

المؤلفون: Jan-Stefan van der Walt, Joji Mori, Takahiro Nakayama, Kenichi Inoue, Yoshinori Ito, George W. Sledge, Yasuo Miyoshi, Tsutomu Kawaguchi, Masato Takahashi, Yoshinori Tanizawa, Masakazu Toi, Antonio Llombart-Cussac, Norikazu Masuda, Hiroji Iwata, Hirofumi Mukai, Sachi Sakaguchi

المصدر: Breast Cancer (Tokyo, Japan)

مصطلحات موضوعية: Adult, Oncology, medicine.medical_specialty, Antineoplastic Agents, Hormonal, Receptor, ErbB-2, Population, Aminopyridines, Phases of clinical research, Triple Negative Breast Neoplasms, Neutropenia, Placebo, Breast cancer, Double-Blind Method, Japan, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, medicine, Clinical endpoint, Humans, Pharmacology (medical), Radiology, Nuclear Medicine and imaging, education, Fulvestrant, Aged, Aged, 80 and over, education.field_of_study, Cyclin-dependent kinase 4 and 6 inhibitor, business.industry, Hazard ratio, General Medicine, Middle Aged, medicine.disease, Abemaciclib, Quality of Life, Benzimidazoles, Female, Original Article, business, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c71f889661f19ce20b881eac8a2ec03f
http://hdl.handle.net/2433/277491

المؤلفون: Gomes, Inês Fernandes

المساهمون: Casimiro, Sandra Cristina Cara de Anjo, Costa, Luís António Marques da

مصطلحات موضوعية: cancro da mama (CM), resistência à terapia, via de sinalização do recetor ativador do fator nuclear-kB (RANK), inibidores de cinases dependentes de ciclina 4 e 6 (iCDK4/6), inibidores do ligando do RANK (iRANKL), breast cancer (BC), therapy resistance, receptor activator of nuclear factor-kB (RANK) signaling pathway, cyclin dependent kinase 4 and 6 inhibitors (CDK4/6i), RANK ligand inhibitors (RANKLi), Domínio/Área Científica::Ciências Médicas::Ciências da Saúde

Relation: info:eu-repo/grantAgreement/FCT//SFRH%2FBD%2F139178%2F2018/PT; info:eu-repo/grantAgreement/FCT/3599-PPCDT/PTDC%2FMED-ONC%2F28636%2F2017/PT; http://hdl.handle.net/10451/64865; 101599617

الاتاحة: http://hdl.handle.net/10451/64865

المؤلفون: Neven, Patrick, Dullens, Lieke, Han, Sileny, Deblander, Anne, Van Herck, Yannick, Van Houdt, Maxime, Wildiers, Hans

المصدر: Transl Breast Cancer Res ; ISSN:2218-6778 ; Volume:4

مصطلحات موضوعية: Metastatic breast cancer (MBC), abemaciclib, cyclin-dependent kinase 4 and 6 inhibitors (CDK4/6i), hormone receptor-positive (HR+), tucidinostat

Relation: https://doi.org/10.21037/tbcr-23-41; https://pubmed.ncbi.nlm.nih.gov/38751459; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11093079/

الاتاحة: https://doi.org/10.21037/tbcr-23-41
https://pubmed.ncbi.nlm.nih.gov/38751459
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11093079/

المؤلفون: Minekazu Yamaguchi, Shingo Yamagata, Shigeru Sakano, Miyako Horie, Kazutaka Kurokohchi, Tsunetaka Kijima, Kazunari Ishitobi, Satoshi Honda, Tatsuo Horie

المصدر: Molecular and Clinical Oncology

مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, Side effect, Cmax, Renal function, abemaciclib, Gastroenterology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, renal dysfunction, Internal medicine, Diabetes mellitus, medicine, Creatinine, diabetes, business.industry, creatinine, Articles, medicine.disease, Metastatic breast cancer, severe hypoglycaemia, Glimepiride, Oncology, chemistry, 030220 oncology & carcinogenesis, cyclin-dependent kinase 4 and 6, protein-binding, 030211 gastroenterology & hepatology, Liver function, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01aa6a9fcb32a822776e0b950407e102
https://doi.org/10.3892/mco.2021.2223

المؤلفون: Hamilton, Erika, Cortes, Javier, Ozyilkan, Ozgur, Chen, Shin-Cheh, Petrakova, Katarina, Manikhas, Aleksey, Jerusalem, Guy, Hegg, Roberto, Huober, Jens, Chapman, Sonya C., Lu, Yi, Hardebeck, Molly C., Bear, Melissa M., Johnston, Erica L., Martin, Miguel

المصدر: Clinical Breast Cancer (2020)

مصطلحات موضوعية: Cyclin-dependent kinase 4 and 6, Endocrine therapy, HER2(−), Hormone receptor-positive, MBC, oncology, Human health sciences, Sciences de la santé humaine, Oncologie

Relation: urn:issn:1526-8209; https://orbi.uliege.be/handle/2268/252333; info:hdl:2268/252333; info:pmid:33148479

الاتاحة: https://orbi.uliege.be/handle/2268/252333
https://doi.org/10.1016/j.clbc.2020.09.011

المؤلفون: Yen-Shen Lu, Debu Tripathy, Seock-Ah Im

المساهمون: Rocca, Andrea, Melegari, Elisabetta, Palleschi, Michela

مصطلحات موضوعية: Oncology, cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitor, advanced breast cancer, luminal, medicine.medical_specialty, palbociclib, business.industry, Endocrine therapy, MEDLINE, Aminopyridines, Breast Neoplasms, Ribociclib, cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors, ribociclib, General Medicine, medicine.disease, Breast cancer, Purines, Internal medicine, medicine, Humans, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7faee4d42fba112845a28cbb4a2bd4
https://hdl.handle.net/11368/3040180

المؤلفون: Kinga Chmielewska, Żaneta Rygielska, Dominika Tempka, Paulina Tokarz, Magdalena Kluska, László Virág, Agnieszka Robaszkiewicz, Julita Pietrzak

المصدر: Redox Biology
Redox Biology, Vol 15, Iss C, Pp 316-326 (2018)

مصطلحات موضوعية: 0301 basic medicine, Cell cycle checkpoint, Lung Neoplasms, DNA Repair, Pyridines, Clinical Biochemistry, Poly (ADP-Ribose) Polymerase-1, Aminopyridines, BRCA1, breast cancer type 1 susceptibility protein, Biochemistry, Piperazines, DNA Glycosylases, PARP1, BRCA2, breast cancer type 2 susceptibility protein, SSBR, Single-strand break repair, Promoter Regions, Genetic, lcsh:QH301-705.5, BER, base excision repair, AP, apurinic/apyrimidinic site, Etoposide, lcsh:R5-920, iPARP1, inhibitor of PARP1, olaparib, Chemistry, Base excision repair, PD0332991, inhibitor of CDK4/6, palbociclib, Imbrance, CDK4/6, cyclin-dependent kinases 4 and 6, RAD51, RAD51 recombinase, HDAC1, histone deacetylase 1, Gene Expression Regulation, Neoplastic, EZH2, enhancer of zeste 2 polycomb repressive complex 2 subunit, DNA-PKcs/Ku, protein kinase, DNA-activated, catalytic polypeptide, iHDAC, inhibitor of histone deacetylases, 8-oxoguanine glycosylase (OGG1), lcsh:Medicine (General), DNAP β, DNA polymerase, beta, Research Paper, OGG1, 8-oxoguanine DNA glycosylase, NU6140, cyclin-dependent kinase 2 (CDK2) inhibitor, DNA damage, PCNA, proliferating cell nuclear antigen, FapyGua, 2,6-diamino-4-hydroxy-5-formamidopyrimidine, PARP1, poly(ADP-ribose) polymerase 1, XRCC1, X-ray repair cross complementing 1, 03 medical and health sciences, pCMV3-PARP1, A549 cells transfected with vector carrying cDNA for PARP1, expressing higher level of PARP1 than pCMV3-EMPTY upon cell cycle arrest in G1, 8-oxo-Gua, 7,8-dihydro-8-oxoguanine, Cell Line, Tumor, Humans, iPRC2, inhibitor of EZH2, UNC1999, Cell growth, iOGG1, inhibitor of OGG1, O8, Poly(ADP-ribose) polymerase 1 (PARP1), Organic Chemistry, Daunorubicin, Oxo-8-G, 8-oxo-7,8-dihydroguanosine, pCMV3-EMPTY, A549 cells transfected with control vector, expressing basal level of PARP1, Cyclin-Dependent Kinase 4, Reactive oxygen species (ROS), DNA Repair Pathway, Cell Cycle Checkpoints, Hydrogen Peroxide, iCDK4/6, inhibitor of CDK4/6, MRE11, double strand break repair nuclease, SMARCA4, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4, 030104 developmental biology, lcsh:Biology (General), CDK2, cyclin-dependent kinase 2, LEE011, inhibitor of CDK4/6, ribociclib, Kisqali, DNA glycosylase, Purines, Cancer cell, Cancer research, NAC, N-acetyl-cysteine, HR, homologous recombination, Cyclin-dependent kinase 4 and 6 (iCDK4/6), DNA Damage

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de6f77c1a1f3468245c3982273c155af
https://pubmed.ncbi.nlm.nih.gov/29306194

المؤلفون: Gottfried E. Konecny

المصدر: Current Opinion in Obstetrics and Gynecology, vol 28, iss 1
Current opinion in obstetrics & gynecology, vol 28, iss 1
Konecny, GE. (2016). Cyclin-dependent kinase pathways as targets for women's cancer treatment. Current Opinion in Obstetrics and Gynecology, 28(1), 42-48. doi: 10.1097/GCO.0000000000000243. UCLA: Retrieved from: http://www.escholarship.org/uc/item/9427m46m

مصطلحات موضوعية: 0301 basic medicine, Lymphoma, Pyridines, Aminopyridines, Lymphoma, Mantle-Cell, Pharmacology, Piperazines, chemistry.chemical_compound, 0302 clinical medicine, Neoplasms, Antineoplastic Combined Chemotherapy Protocols, Abemaciclib, Melanoma, biology, Cell Cycle, Obstetrics and Gynecology, Liposarcoma, Neoplasms, Germ Cell and Embryonal, 030220 oncology & carcinogenesis, cyclin-dependent kinase 4 and 6 inhibition, Female, Signal Transduction, palbociclib, Antineoplastic Agents, Breast Neoplasms, Palbociclib, abemaciclib (LY2835219) and ribociclib, Paediatrics and Reproductive Medicine, 03 medical and health sciences, Breast cancer, Cyclin-dependent kinase, medicine, Humans, Obstetrics & Reproductive Medicine, neoplasms, Protein Kinase Inhibitors, Cyclin-dependent kinase 4, business.industry, Cyclin-Dependent Kinase 4, Cyclin-Dependent Kinase 6, Mantle-Cell, medicine.disease, 030104 developmental biology, chemistry, Purines, biology.protein, Cancer research, Germ Cell and Embryonal, Cyclin-dependent kinase 6, Ovarian cancer, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e165f4edc5db23ae0556912fd5ea469d
https://pubmed.ncbi.nlm.nih.gov/26642065

المؤلفون: 10207516, Inoue, Kenichi, Masuda, Norikazu, Iwata, Hiroji, Takahashi, Masato, Ito, Yoshinori, Miyoshi, Yasuo, Nakayama, Takahiro, Mukai, Hirofumi, van der Walt, Jan-Stefan, Mori, Joji, Sakaguchi, Sachi, Kawaguchi, Tsutomu, Tanizawa, Yoshinori, Llombart-Cussac, Antonio, Sledge, George W., Toi, Masakazu

مصطلحات الفهرس: Abemaciclib, Breast cancer, Cyclin-dependent kinase 4 and 6 inhibitor, journal article

URL: http://hdl.handle.net/2433/277491
10.1007/s12282-021-01239-8