المؤلفون: Jayapriya Venkatesan, Durba Roy

المصدر: Chemical Physics Impact, Vol 7, Iss , Pp 100330- (2023)

مصطلحات موضوعية: Molecular dynamics, Cyclotides, Cyclic cystine knot, Principal component analysis, Frustrated, Physics, QC1-999, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S266702242300169X; https://doaj.org/toc/2667-0224

URL الوصول: https://doaj.org/article/137e5982a63642339ea31c4bf8354751

المؤلفون: Edin Muratspahić (9578931), Nataša Tomašević (11019445), Shahrooz Nasrollahi-Shirazi (11184223), Jasmin Gattringer (11110986), Fabiola Susanna Emser (11184226), Michael Freissmuth (152034), Christian W. Gruber (176571)

مصطلحات موضوعية: Biophysics, Biochemistry, Pharmacology, Biotechnology, Ecology, Science Policy, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, T 20K, ligand, μ M range, bioluminescence resonance energy tr., MS, G protein-coupled receptor, efficacy, cyclotide-based KOR modulators, cyclic cystine knot, GPCR, plant-derived disulfide-rich peptides, κ- opioid receptor

Relation: https://figshare.com/articles/journal_contribution/Plant-Derived_Cyclotides_Modulate_Opioid_Receptor_Signaling/15052438

الاتاحة: https://doi.org/10.1021/acs.jnatprod.1c00301.s001

المؤلفون: Park, Sungkyu, 1979

المساهمون: Ulf, Göransson, Professor, Bohlin, Lars, Professor emeritus, Marahiel, Mohamed, Professor

المصدر: Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Pharmacy.

مصطلحات موضوعية: cyclotide, cyclic cystine knot, evolution, peptide synthesis, chemical ligation, QSAR, Viola, Violaceae, phylogeny, Farmakognosi, Pharmacognosy

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-292668
https://uu.diva-portal.org/smash/get/diva2:926556/FULLTEXT01.pdf
https://uu.diva-portal.org/smash/get/diva2:926556/PREVIEW01.jpg

المؤلفون: O'Brien, Margaret, Smith, Terry

المساهمون: ~

مصطلحات موضوعية: Circular plant peptide, Peptide ligand design, Uterotonic, Chemical pharmacology, Peptide drugs, Cyclic cystine knot, Kalata B1, Uterine contractility, Human myometrium, Drug design, Vasopressin, Antagonists, Binding, Agonist, Mechanism

وصف الملف: application/pdf

Relation: Proceedings Of The National Academy Of Sciences Of The United States Of America; Koehbach, J,O'Brien, M,Muttenthaler, M,Miazzo, M,Akcan, M,Elliott, AG,Daly, NL,Harvey, PJ,Arrowsmith, S,Gunasekera, S,Smith, TJ,Wray, S,Goransson, U,Dawson, PE,Craik, DJ,Freissmuth, M,Gruber, CW (2013) 'Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design'. Proceedings Of The National Academy Of Sciences Of The United States Of America, 110 (52):21183-21188.; http://hdl.handle.net/10379/4667

الاتاحة: http://hdl.handle.net/10379/4667

المؤلفون: Koehbach, J., O'Brien, M., Muttenthaler, M., Miazzo, M., Akcan, M., Elliott, A. G., Daly, N. L., Harvey, P. J., Arrowsmith, S., Gunasekera, S., Smith, T. J., Wray, S., Goransson, U., Dawson, P. E., Craik, D. J., Freissmuth, M., Gruber, C. W.

مصطلحات موضوعية: circular plant peptide, peptide ligand design, uterotonic, chemical pharmacology, peptide drugs, cyclic-cystine-knot, kalata b1, uterine contractility, human myometrium, drug design, vasopressin, antagonists, binding, agonist, mechanism

Relation: Proceedings of the National Academy of Sciences; Koehbach, J. O'Brien, M.; Muttenthaler, M.; Miazzo, M.; Akcan, M.; Elliott, A. G.; Daly, N. L.; Harvey, P. J.; Arrowsmith, S.; Gunasekera, S.; Smith, T. J.; Wray, S.; Goransson, U.; Dawson, P. E.; Craik, D. J.; Freissmuth, M.; Gruber, C. W. (2013). Oxytocic plant cyclotides as templates for peptide g protein-coupled receptor ligand design. Proceedings of the National Academy of Sciences 110 (52), 21183-21188; 0027-8424,1091-6490; http://hdl.handle.net/10379/12293

الاتاحة: http://hdl.handle.net/10379/12293
https://doi.org/10.1073/pnas.1311183110

المؤلفون: Herrmann, Anders, 1976

المساهمون: Göransson, Ulf, Doctor, Bohlin, Lars, Professor, Kinghorn, Douglas, Professor

المصدر: Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Pharmacy.

مصطلحات موضوعية: Pharmacognosy, cyclotide, cytotoxic, anti-tumour, macrocyclic, cyclic cystine knot, Alpine violet, Sweet violet, Viola, Violaceae, chemical modifications, structure-activity studies, mass spectroscopy, cDNA clones, Farmakognosi

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-8283
https://uu.diva-portal.org/smash/get/diva2:170906/FULLTEXT01.pdf
https://uu.diva-portal.org/smash/get/diva2:170906/COVER01.pdf

المؤلفون: Gruber, Christian, O'Brien, Margaret

مصطلحات موضوعية: women's health, gynaecology, labour, myometrial smooth muscle, oxytocin, cyclotides, plants, corticotropin-releasing hormone, human myometrial cells, supercritical-fluid extraction, smooth-muscle-cells, cyclic-cystine-knot, isolated rat uterus, human-fetal membranes, tumor-necrosis-factor, protein-kinase-c, medicinal-plants

Relation: Planta Medica; Gruber, Christian; O'Brien, Margaret (2010). Uterotonic plants and their bioactive constituents. Planta Medica 77 (3), 207-220; 0032-0943,1439-0221; http://hdl.handle.net/10379/11743

الاتاحة: http://hdl.handle.net/10379/11743
https://doi.org/10.1055/s-0030-1250317

المؤلفون: Svangård, Erika, 1975

المساهمون: Claeson, Per, Doc., Bohlin, Lars, Prof., Göransson, Ulf, Dr., Cardellina II, John H., Prof.

المصدر: Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Pharmacy.

مصطلحات موضوعية: Pharmacognosy, cyclotide, cytotoxic, cancer, cyclic cystine knot, Viola, Violaceae, liposome, hollow fibre, homology modelling, mass spectrometry, amphipathic, structure–activity, tumour, membrane disruption, necrosis, Farmakognosi, PHARMACY, FARMACI

وصف الملف: electronic

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-6028
https://uu.diva-portal.org/smash/get/diva2:167192/FULLTEXT01.pdf
https://uu.diva-portal.org/smash/get/diva2:167192/COVER01.pdf

المؤلفون: David J. Craik, Norelle L. Daly, Clement Waine

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://download.bioon.com.cn/upload/month_0903/20090302_98aabfe23002e37ee034Ylmvo7KODb9Z.attach.pdf.

مصطلحات موضوعية: Cyclic cystine knot, Kalata, Cyclotides, Knotted proteins, Inhibitor cystine knot

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.475.3749; http://download.bioon.com.cn/upload/month_0903/20090302_98aabfe23002e37ee034Ylmvo7KODb9Z.attach.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.475.3749
http://download.bioon.com.cn/upload/month_0903/20090302_98aabfe23002e37ee034Ylmvo7KODb9Z.attach.pdf

المؤلفون: Aaron G. Poth, Michelle L. Colgrave, David J. Craik, Anjaneya S. Ravipati, Quentin Kaas, Conan K. Wang, Sónia Troeira Henriques

المصدر: ResearcherID
ACS Chemical Biology

مصطلحات موضوعية: Models, Molecular, Spectrometry, Mass, Electrospray Ionization, Erythrocytes, Magnetic Resonance Spectroscopy, 060110 Receptors and Membrane Biology, cyclic cystine knot, De Novo Sequencing of cyclic peptides, Lysine, Cyclotides, Cystine Knot Motifs, Biochemistry, Subclass, Humans, Amino Acid Sequence, Cells, Cultured, biology, Host (biology), General Medicine, biology.organism_classification, 030406 Proteins and Peptides, Evolutionary biology, 030100 ANALYTICAL CHEMISTRY, peptide-membrane interactions, Plant species, Molecular Medicine, Melicytus chathamicus, Peptides, Disulfide-rich peptides, Violaceae, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ed3d9aebb9f083dc8ee7b293deabd8a
https://doi.org/10.1021/acschembio.5b00454

المؤلفون: Wang, Conan K., Craik, David J.

مصطلحات موضوعية: Sunflower Trypsin-Inhibitor, Cyclic-Cystine-Knot, Cyclotide Kalata B1, Protein-Protein Interaction, Cell-Penetrating-Peptides, Substrate-Guided Design, Mcoti-Ii, Theta-Defensins, Multiple-Sclerosis, Potent Inhibitors, 1307 Cell Biology, 1312 Molecular Biology

Relation: orcid:0000-0002-7973-7632; orcid:0000-0003-0007-6796; DP150100443

الاتاحة: https://espace.library.uq.edu.au/view/UQ:728335/UQ728335_OA.pdf
https://espace.library.uq.edu.au/view/UQ:728335

المؤلفون: Bobey, Antonio Fernandez, Ferreira Pinto, Meri Emili, Cilli, Eduardo Maffud, Lopes, Norberto Peporine, Bolzani, Vanderlan da Silva

مصطلحات موضوعية: Cyclic Cystine-Knot, Anti-Hiv Cyclotides, Plant Cyclotides, Cycloviolacin O2, Kalata B1, Peptides, Identification, Proliferation, Diversity, Proteins

Relation: orcid:0000-0003-0663-0233; 465637/2014-0; 2014/50926-0; 2013/07600-3; 2017/17098-4; 142286/2016-8; 162855/2015-0

الاتاحة: https://espace.library.uq.edu.au/view/UQ:1a7e96f

المؤلفون: Pinto, Meri Emili F., Najas, Jhenny Z. G., Magalhães, Luma G., Bobey, Antonio F., Mendonça, Jacqueline N., Lopes, Norberto P., Leme, Flávia M., Teixeira, Simone P., Trovó, Marcelo, Andricopulo, Adriano D., Koehbach, Johannes, Gruber, Christian W., Cilli, Eduardo Maffud, Bolzani, Vanderlan S.

مصطلحات موضوعية: Cyclic cystine knot, Plant cyclotides, Cytotoxic cyclotides, Macrocyclic peptides, Oldenlandia-affinis, Structural motif, Cycloviolacin O2, Viola-tricolor, Kalata B1, Proteins, 1313 Molecular Medicine, 1602 Analytical Chemistry, 1605 Organic Chemistry, 2707 Complementary and alternative medicine, 3002 Drug Discovery, 3003 Pharmaceutical Science, 3004 Pharmacology

Relation: orcid:0000-0003-0663-0233; orcid:0000-0002-7050-2693; orcid:0000-0001-6060-7048; 2017/17098-4; 162855/2015-0; 2010/52327-5; 2013/07600-3; 465637/2014-0; 2014/50265-3; 150244/2014-2; Not set; I3243

الاتاحة: https://espace.library.uq.edu.au/view/UQ:3843e3c

المؤلفون: Ravipati, Anjaneya S., Poth, Aaron G., Henriques, Sonia Troeira, Bhandari, Murari, Huang, Yen-Hua, Nino, Jaime, Colgrave, Michelle L., Craik, David J.

مصطلحات موضوعية: Cyclic-Cystine-Knot, Polypeptide Kalata B1, Anti-Hiv Activity, Oldenlandia-Affinis, Drug Design, Structural-Characterization, Biological-Activity, Circular Proteins, Flowering Plants, Viola-Odorata, 1313 Molecular Medicine, 1602 Analytical Chemistry, 1605 Organic Chemistry, 2707 Complementary and alternative medicine, 3002 Drug Discovery, 3003 Pharmaceutical Science, 3004 Pharmacology

Relation: orcid:0000-0002-1497-8347; orcid:0000-0001-9564-9651; orcid:0000-0001-6937-2660; orcid:0000-0003-0007-6796; DE120103152; DP150100443; FL150100146

الاتاحة: https://espace.library.uq.edu.au/view/UQ:674028/UQ674028_OA.pdf
https://espace.library.uq.edu.au/view/UQ:674028

المؤلفون: Fahradpour, Mohsen, Keov, Peter, Tognola, Carlotta, Perez-Santamarina, Estela, McCormick, Peter J., Ghassempour, Alireza, Gruber, Christian W.

مصطلحات موضوعية: Cyclic-Cystine-Knot, Protein-Coupled Receptors, Plant Cyclotides, Circular Peptides, Flowering Plants, Viola-Tricolor, Drug Design, Kalata B1, Discovery, Transcriptome, 2736 Pharmacology (medical), 3004 Pharmacology

Relation: orcid:0000-0002-3829-6455; orcid:0000-0001-6060-7048; I3243; FT140100730; CM1207

الاتاحة: https://espace.library.uq.edu.au/view/UQ:692486

المؤلفون: Daly, Norelle L., Rosengren, K. Johan

المساهمون: David Craik

مصطلحات موضوعية: Cyclic-Cystine-Knot, Polypeptide Kalata B1, Squash Trypsin-Inhibitor, Oldenlandia-Affinis, Circular Proteins, Plant Cyclotides, Momordica-Cochinchinensis, Membrane Interactions, Insecticidal Activity, Scanning Mutagenesis

Relation: orcid:0000-0002-5007-8434

الاتاحة: https://espace.library.uq.edu.au/view/UQ:696369

المؤلفون: Akcan, Muharrem, Craik, David J.

المساهمون: Glenn F. King

مصطلحات موضوعية: Nicotinic Acetylcholine-Receptors, Alpha-Conotoxin Auib, Native Chemical Ligation, Disulfide Bond Isomers, Cyclic Cystine Knot, Backbone Cyclization, Norepinephrine Transporter, Calcium-Channels, Gaba(B) Receptor, Neuropathic Pain

Relation: orcid:0000-0003-0007-6796

الاتاحة: https://espace.library.uq.edu.au/view/UQ:355544

المؤلفون: Norelle L. Daly, K. Johan Rosengren, Sónia Troeira Henriques, Anne C. Conibear, David J. Craik

المصدر: Journal of Biological Chemistry

مصطلحات موضوعية: alpha-Defensins, 060110 Receptors and Membrane Biology, Stereochemistry, Nuclear Magnetic Resonance, Amino Acid Motifs, Antimicrobial peptides, Cystine, Peptide, Biochemistry, Protein Structure, Secondary, Defensins, Disulfide, chemistry.chemical_compound, Protein structure, medicine, Humans, Cyclic peptides, Nuclear Magnetic Resonance, Biomolecular, Molecular Biology, chemistry.chemical_classification, integumentary system, Protein Stability, fungi, Disulfide bond, hemic and immune systems, Cell Biology, respiratory system, bacterial infections and mycoses, Cyclic peptide, 030406 Proteins and Peptides, chemistry, Mechanism of action, Protein Structure and Folding, Cyclic Cystine Knot, 060112 Structural Biology (incl. Macromolecular Modelling), Tetha-defensins, medicine.symptom, Peptides, Antibacterial activity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18dd8aa65cc8c13315f4cf1f45be9156
https://doi.org/10.1074/jbc.m113.451047

المؤلفون: Manuel Plan, Rosengren, K. Johan, Sando, Lillian, Daly, Norelle L., Craik, David J.

مصطلحات موضوعية: cyclotide, cyclic peptide, cyclic cystine knot, kalata, hemolytic, NMR

Relation: orcid:0000-0002-5007-8434; orcid:0000-0003-0007-6796

الاتاحة: https://espace.library.uq.edu.au/view/UQ:228273

المؤلفون: Gruber, Christian W.

مصطلحات موضوعية: Protein-Disulfide-Isomerase, Coffee Family Rubiaceae, Cyclic Cystine Knot, Oldenlandia-Affinis, Phylogenetic-Relationships, Structural Motif, Classification, Sequences, Rbcl, Biosynthesis

Relation: P 22889

الاتاحة: https://espace.library.uq.edu.au/view/UQ:695977