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    Relation: Brennan, Julia R.; Cornett, Ashley; Chang, Brian; Crotts, Sarah J.; Nourmohammadi, Zahra; Lombaert, Isabelle; Hollister, Scott J.; Zopf, David A. (2021). "Preclinical assessment of clinically streamlined, 3D‐printed, biocompatible single‐ and two‐stage tissue scaffolds for ear reconstruction." Journal of Biomedical Materials Research Part B: Applied Biomaterials 109(3): 394-400.; https://hdl.handle.net/2027.42/166223; https://dx.doi.org/10.7302/146; Journal of Biomedical Materials Research Part B: Applied Biomaterials; Shergold OA, Fleck NA. Experimental investigation into the deep penetration of soft solids by sharp and blunt punches, with application to the piercing of skin. J Biomech Eng. 2005; 127: 838 ‐ 848.; Shergold OA, Fleck NA. Mechanisms of deep penetration of soft solids with application to the injection and wounding of skin. Proc R Soc Lond A. 2004; 460: 3037 ‐ 3358.; Maas SA, Ateshian GA, Weiss JA. FEBio: history and advances. Ann Rev Biomed Eng. 2017; 19: 279 ‐ 299.; Maas SA, Ellis BJ, Ateshian GA, Weiss JA. FEBio: finite elements for biomechanics. J Biomech Eng. 2012; 134: 011005.; Romo T, Baratelli R, Raunig H. Avoiding complications of microtia and otoplasty. Facial Plast Surg. 2012; 28: 333 ‐ 339.; Han SE, Lim SY, Pyon JK, Bang SI, Mun GH, Oh KS. Aesthetic auricular reconstruction with autologous rib cartilage grafts in adult microtia patients. J Plast Reconstr Aesthet Surg. 2015; 68: 1085 ‐ 1094.; Pruzinsky T. Social and psychological effects of major craniofacial deformity. Cleft Palate Craniofac J. 1992; 29: 578 ‐ 584.; Nagata A. A new method of total reconstruction of the auricle for microtia. Plast Reconstr Surg. 1993; 92: 187 ‐ 201.; Fling PW, Haughey BH, Lund VJ, et al. Cummings Otolaryngology. Philadelphia, PA: Elsevier; 2015: 3624.; Thomson HG, Kim TY, Ein SH. Residual problems in chest donor sites after microtia reconstruction: a long‐term study. Plast Reconstr Surg. 1995; 95: 961 ‐ 968.; Constantine KK, Gilmore J, Lee K, Leach J Jr. Comparison of microtia reconstruction outcomes using rib cartilage vs porous polyethylene implant. JAMA Facial Plast Surg. 2014; 16: 240 ‐ 244.; Kamil SH, Vacanti MP, Aminuddin BS, Jackson MJ, Vacanti CA, Eavey RD. Tissue engineering of a human sized and shaped auricle using a mold. Laryngoscope. 2004; 114: 867 ‐ 870.; Zopf DA, Mitsak AG, Flanagan CL, Wheeler M, Green GE, Hollister SJ. Computer aided‐designed, 3‐dimensionally printed porous tissue bioscaffolds for craniofacial soft tissue reconstruction. Otolaryngol Head Neck Surg. 2015; 152: 57 ‐ 62.; Jeong CG, Zhang H, Hollister SJ. Three‐dimensional poly(1,8‐octanediol‐co‐citrate) scaffold pore shape and permeability effects on sub‐cutaneous in vivo chondrogenesis using primary chondrocytes. Acta Biomater. 2011; 7: 505 ‐ 514.; Hollister SJ, Lin CY, Saito E, et al. Engineering craniofacial scaffolds. Orthod Craniofacial Res. 2005; 8: 162 ‐ 173.; Hollister SJ. Porous scaffold design for tissue engineering. Nat Mater. 2006; 5: 590.; Zopf DA, Hollister SJ, Nelson ME, Ohye RG, Green GE. Bioresorbable airway splint created with three‐dimensional printer. N Engl J Med. 2013; 368: 2043 ‐ 2045.; Les AS, Ohye RG, Filbrun AG, et al. 3D‐printed, externally implanted, bioresorbable airway splints for severe tracheabronchomalacia. Laryngoscope. 2019; 129: 1763 ‐ 1771.; Lee JS, Kim BS, Seo D, Park JH, Cho DW. Three‐dimensional cell printing of large‐volume tissues: application to ear regeneration. Tissue Eng Part C Meth. 2017; 23 ( 3 ): 136 ‐ 145.; Bichara DA, O’Sullivan NA, Pomerantseva I, et al. The tissue‐engineered auricle: past, present, and future. Tissue Eng B Rev. 2011; 18 ( 1 ): 51 ‐ 61.; Bauer BS. Reconstruction of Microtia. Plast Reconstr Surg. 2009; 124: 142e ‐ 26c.; Siddiqui N, Asawa S, Birru B, Baadhe R, Rao S. PCL‐based composite scaffold matrices for tissue engineering applications. Molecular Biotech. 2018; 60: 506 ‐ 532.; Zopf DA, Flanagan CL, Nasser HB, Mitsak AG, Huq FS, Rajendran V, Green GE, Hollister SJ. Biomechanical evaluation of human and porcine auricular cartilage. Laryngoscope. 2015; 125 ( 8 ): 262 – 268. https://doi.org/10.1002/lary.25040. PubMed PMID: 25891012; PMCID: PMC4512857.; Zopf DA, Flanagan CL, Mitsak AG, Brennan JR, Hollister SJ. Pore architecture effects on chondrogenic potential of patient‐specific 3‐dimensionally printed porous tissue bioscaffolds for auricular tissue engineering. Int J Pediatr Otorhinolaryngol. 2018; 114: 170 ‐ 174.; Mitsak AG, Kemppainen JM, Harris M, Hollister SJ. Effect of polycaprolactone permeability on bone regeneration in vivo. Tissue Eng. 2011; 17: 1831 ‐ 1839.

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