المؤلفون: Vijay R. Varma (4797432), Youjin Wang (10884494), Yang An (326217), Sudhir Varma (56982), Murat Bilgel (6066809), Jimit Doshi (643398), Cristina Legido-Quigley (718909), João C. Delgado (10884497), Anup M. Oommen (4797435), Jackson A. Roberts (10884500), Dean F. Wong (672684), Christos Davatzikos (280898), Susan M. Resnick (8052875), Juan C. Troncoso (225906), Olga Pletnikova (225888), Richard O’Brien (3850429), Eelko Hak (217714), Brenda N. Baak (10884503), Ruth Pfeiffer (36526), Priyanka Baloni (2920530), Siamak Mohmoudiandehkordi (10884506), Kwangsik Nho (114023), Rima Kaddurah-Daouk (152187), David A. Bennett (229710), Shahinaz M. Gadalla (10011616), Madhav Thambisetty (133912)

مصطلحات موضوعية: Medicine, Cell Biology, Neuroscience, Physiology, Biotechnology, Mental Health, brain amyloid deposition, BAS use, cohort study, brain amyloid accumulation, WML, ROSMAP, brain BA receptor gene expression, serum concentrations, Religious Orders Study, HR, FDR, Clinical Practice Research Datalink, ADNI, 3- step study design, Baltimore Longitudinal Study, cholesterol catabolism, gene expression, CPRD, bile acid sequestrants, serum concentrations CA, 7α- OHC, Bile acid synthesis, CON, pharmacoepidemiologic study Background

Relation: https://figshare.com/articles/journal_contribution/Supporting_information_text_/14687759

الاتاحة: https://doi.org/10.1371/journal.pmed.1003615.s002

المؤلفون: Vijay R. Varma (4797432), Youjin Wang (10884494), Yang An (326217), Sudhir Varma (56982), Murat Bilgel (6066809), Jimit Doshi (643398), Cristina Legido-Quigley (718909), João C. Delgado (10884497), Anup M. Oommen (4797435), Jackson A. Roberts (10884500), Dean F. Wong (672684), Christos Davatzikos (280898), Susan M. Resnick (8052875), Juan C. Troncoso (225906), Olga Pletnikova (225888), Richard O’Brien (3850429), Eelko Hak (217714), Brenda N. Baak (10884503), Ruth Pfeiffer (36526), Priyanka Baloni (2920530), Siamak Mohmoudiandehkordi (10884506), Kwangsik Nho (114023), Rima Kaddurah-Daouk (152187), David A. Bennett (229710), Shahinaz M. Gadalla (10011616), Madhav Thambisetty (133912)

مصطلحات موضوعية: Medicine, Cell Biology, Neuroscience, Physiology, Biotechnology, Mental Health, brain amyloid deposition, BAS use, cohort study, brain amyloid accumulation, WML, ROSMAP, brain BA receptor gene expression, serum concentrations, Religious Orders Study, HR, FDR, Clinical Practice Research Datalink, ADNI, 3- step study design, Baltimore Longitudinal Study, cholesterol catabolism, gene expression, CPRD, bile acid sequestrants, serum concentrations CA, 7α- OHC, Bile acid synthesis, CON, pharmacoepidemiologic study Background

Relation: https://figshare.com/articles/journal_contribution/ROSMAP_scRNA-Seq_BA_receptor_gene_expression_data_availability_/14687765

الاتاحة: https://doi.org/10.1371/journal.pmed.1003615.s004

المؤلفون: Vijay R. Varma (4797432), Youjin Wang (10884494), Yang An (326217), Sudhir Varma (56982), Murat Bilgel (6066809), Jimit Doshi (643398), Cristina Legido-Quigley (718909), João C. Delgado (10884497), Anup M. Oommen (4797435), Jackson A. Roberts (10884500), Dean F. Wong (672684), Christos Davatzikos (280898), Susan M. Resnick (8052875), Juan C. Troncoso (225906), Olga Pletnikova (225888), Richard O’Brien (3850429), Eelko Hak (217714), Brenda N. Baak (10884503), Ruth Pfeiffer (36526), Priyanka Baloni (2920530), Siamak Mohmoudiandehkordi (10884506), Kwangsik Nho (114023), Rima Kaddurah-Daouk (152187), David A. Bennett (229710), Shahinaz M. Gadalla (10011616), Madhav Thambisetty (133912)

مصطلحات موضوعية: Medicine, Cell Biology, Neuroscience, Physiology, Biotechnology, Mental Health, brain amyloid deposition, BAS use, cohort study, brain amyloid accumulation, WML, ROSMAP, brain BA receptor gene expression, serum concentrations, Religious Orders Study, HR, FDR, Clinical Practice Research Datalink, ADNI, 3- step study design, Baltimore Longitudinal Study, cholesterol catabolism, gene expression, CPRD, bile acid sequestrants, serum concentrations CA, 7α- OHC, Bile acid synthesis, CON, pharmacoepidemiologic study Background

Relation: https://figshare.com/articles/journal_contribution/S3_Table_-/14687768

الاتاحة: https://doi.org/10.1371/journal.pmed.1003615.s005

المؤلفون: Vijay R. Varma (4797432), Youjin Wang (10884494), Yang An (326217), Sudhir Varma (56982), Murat Bilgel (6066809), Jimit Doshi (643398), Cristina Legido-Quigley (718909), João C. Delgado (10884497), Anup M. Oommen (4797435), Jackson A. Roberts (10884500), Dean F. Wong (672684), Christos Davatzikos (280898), Susan M. Resnick (8052875), Juan C. Troncoso (225906), Olga Pletnikova (225888), Richard O’Brien (3850429), Eelko Hak (217714), Brenda N. Baak (10884503), Ruth Pfeiffer (36526), Priyanka Baloni (2920530), Siamak Mohmoudiandehkordi (10884506), Kwangsik Nho (114023), Rima Kaddurah-Daouk (152187), David A. Bennett (229710), Shahinaz M. Gadalla (10011616), Madhav Thambisetty (133912)

مصطلحات موضوعية: Medicine, Cell Biology, Neuroscience, Physiology, Biotechnology, Mental Health, brain amyloid deposition, BAS use, cohort study, brain amyloid accumulation, WML, ROSMAP, brain BA receptor gene expression, serum concentrations, Religious Orders Study, HR, FDR, Clinical Practice Research Datalink, ADNI, 3- step study design, Baltimore Longitudinal Study, cholesterol catabolism, gene expression, CPRD, bile acid sequestrants, serum concentrations CA, 7α- OHC, Bile acid synthesis, CON, pharmacoepidemiologic study Background

Relation: https://figshare.com/articles/journal_contribution/STROBE_checklist_/14687762

الاتاحة: https://doi.org/10.1371/journal.pmed.1003615.s003

المؤلفون: Vijay R. Varma (4797432), Youjin Wang (10884494), Yang An (326217), Sudhir Varma (56982), Murat Bilgel (6066809), Jimit Doshi (643398), Cristina Legido-Quigley (718909), João C. Delgado (10884497), Anup M. Oommen (4797435), Jackson A. Roberts (10884500), Dean F. Wong (672684), Christos Davatzikos (280898), Susan M. Resnick (8052875), Juan C. Troncoso (225906), Olga Pletnikova (225888), Richard O’Brien (3850429), Eelko Hak (217714), Brenda N. Baak (10884503), Ruth Pfeiffer (36526), Priyanka Baloni (2920530), Siamak Mohmoudiandehkordi (10884506), Kwangsik Nho (114023), Rima Kaddurah-Daouk (152187), David A. Bennett (229710), Shahinaz M. Gadalla (10011616), Madhav Thambisetty (133912)

مصطلحات موضوعية: Medicine, Cell Biology, Neuroscience, Physiology, Biotechnology, Mental Health, brain amyloid deposition, BAS use, cohort study, brain amyloid accumulation, WML, ROSMAP, brain BA receptor gene expression, serum concentrations, Religious Orders Study, HR, FDR, Clinical Practice Research Datalink, ADNI, 3- step study design, Baltimore Longitudinal Study, cholesterol catabolism, gene expression, CPRD, bile acid sequestrants, serum concentrations CA, 7α- OHC, Bile acid synthesis, CON, pharmacoepidemiologic study Background

Relation: https://figshare.com/articles/journal_contribution/Associations_between_serum_metabolite_concentrations_and_PiB_amyloid_status_/14687771

الاتاحة: https://doi.org/10.1371/journal.pmed.1003615.s006

المؤلفون: Vijay R. Varma (4797432), Youjin Wang (10884494), Yang An (326217), Sudhir Varma (56982), Murat Bilgel (6066809), Jimit Doshi (643398), Cristina Legido-Quigley (718909), João C. Delgado (10884497), Anup M. Oommen (4797435), Jackson A. Roberts (10884500), Dean F. Wong (672684), Christos Davatzikos (280898), Susan M. Resnick (8052875), Juan C. Troncoso (225906), Olga Pletnikova (225888), Richard O’Brien (3850429), Eelko Hak (217714), Brenda N. Baak (10884503), Ruth Pfeiffer (36526), Priyanka Baloni (2920530), Siamak Mohmoudiandehkordi (10884506), Kwangsik Nho (114023), Rima Kaddurah-Daouk (152187), David A. Bennett (229710), Shahinaz M. Gadalla (10011616), Madhav Thambisetty (133912)

مصطلحات موضوعية: Medicine, Cell Biology, Neuroscience, Physiology, Biotechnology, Mental Health, brain amyloid deposition, BAS use, cohort study, brain amyloid accumulation, WML, ROSMAP, brain BA receptor gene expression, serum concentrations, Religious Orders Study, HR, FDR, Clinical Practice Research Datalink, ADNI, 3- step study design, Baltimore Longitudinal Study, cholesterol catabolism, gene expression, CPRD, bile acid sequestrants, serum concentrations CA, 7α- OHC, Bile acid synthesis, CON, pharmacoepidemiologic study Background

Relation: https://figshare.com/articles/journal_contribution/Sensitivity_analyses_Associations_between_serum_metabolite_concentrations_and_brain_amyloid-_deposition_longitudinal_changes_in_global_brain_WML_burden_and_rates_of_brain_atrophy_BLSA_/14687774

الاتاحة: https://doi.org/10.1371/journal.pmed.1003615.s007

المؤلفون: Vijay R. Varma (4797432), Youjin Wang (10884494), Yang An (326217), Sudhir Varma (56982), Murat Bilgel (6066809), Jimit Doshi (643398), Cristina Legido-Quigley (718909), João C. Delgado (10884497), Anup M. Oommen (4797435), Jackson A. Roberts (10884500), Dean F. Wong (672684), Christos Davatzikos (280898), Susan M. Resnick (8052875), Juan C. Troncoso (225906), Olga Pletnikova (225888), Richard O’Brien (3850429), Eelko Hak (217714), Brenda N. Baak (10884503), Ruth Pfeiffer (36526), Priyanka Baloni (2920530), Siamak Mohmoudiandehkordi (10884506), Kwangsik Nho (114023), Rima Kaddurah-Daouk (152187), David A. Bennett (229710), Shahinaz M. Gadalla (10011616), Madhav Thambisetty (133912)

مصطلحات موضوعية: Medicine, Cell Biology, Neuroscience, Physiology, Biotechnology, Mental Health, brain amyloid deposition, BAS use, cohort study, brain amyloid accumulation, WML, ROSMAP, brain BA receptor gene expression, serum concentrations, Religious Orders Study, HR, FDR, Clinical Practice Research Datalink, ADNI, 3- step study design, Baltimore Longitudinal Study, cholesterol catabolism, gene expression, CPRD, bile acid sequestrants, serum concentrations CA, 7α- OHC, Bile acid synthesis, CON, pharmacoepidemiologic study Background

Relation: https://figshare.com/articles/journal_contribution/Characteristics_of_participants_who_received_at_least_2_BAS_or_LMT_prescriptions_with_at_least_1_year_of_follow-up_after_second_prescription_/14687777

الاتاحة: https://doi.org/10.1371/journal.pmed.1003615.s008

المؤلفون: Vijay R. Varma (4797432), Youjin Wang (10884494), Yang An (326217), Sudhir Varma (56982), Murat Bilgel (6066809), Jimit Doshi (643398), Cristina Legido-Quigley (718909), João C. Delgado (10884497), Anup M. Oommen (4797435), Jackson A. Roberts (10884500), Dean F. Wong (672684), Christos Davatzikos (280898), Susan M. Resnick (8052875), Juan C. Troncoso (225906), Olga Pletnikova (225888), Richard O’Brien (3850429), Eelko Hak (217714), Brenda N. Baak (10884503), Ruth Pfeiffer (36526), Priyanka Baloni (2920530), Siamak Mohmoudiandehkordi (10884506), Kwangsik Nho (114023), Rima Kaddurah-Daouk (152187), David A. Bennett (229710), Shahinaz M. Gadalla (10011616), Madhav Thambisetty (133912)

مصطلحات موضوعية: Medicine, Cell Biology, Neuroscience, Physiology, Biotechnology, Mental Health, brain amyloid deposition, BAS use, cohort study, brain amyloid accumulation, WML, ROSMAP, brain BA receptor gene expression, serum concentrations, Religious Orders Study, HR, FDR, Clinical Practice Research Datalink, ADNI, 3- step study design, Baltimore Longitudinal Study, cholesterol catabolism, gene expression, CPRD, bile acid sequestrants, serum concentrations CA, 7α- OHC, Bile acid synthesis, CON, pharmacoepidemiologic study Background

Relation: https://figshare.com/articles/journal_contribution/Characteristics_of_participants_with_incident_dementia_events_during_follow-up_/14687780

الاتاحة: https://doi.org/10.1371/journal.pmed.1003615.s009

المؤلفون: Vijay R. Varma (4797432), Youjin Wang (10884494), Yang An (326217), Sudhir Varma (56982), Murat Bilgel (6066809), Jimit Doshi (643398), Cristina Legido-Quigley (718909), João C. Delgado (10884497), Anup M. Oommen (4797435), Jackson A. Roberts (10884500), Dean F. Wong (672684), Christos Davatzikos (280898), Susan M. Resnick (8052875), Juan C. Troncoso (225906), Olga Pletnikova (225888), Richard O’Brien (3850429), Eelko Hak (217714), Brenda N. Baak (10884503), Ruth Pfeiffer (36526), Priyanka Baloni (2920530), Siamak Mohmoudiandehkordi (10884506), Kwangsik Nho (114023), Rima Kaddurah-Daouk (152187), David A. Bennett (229710), Shahinaz M. Gadalla (10011616), Madhav Thambisetty (133912)

مصطلحات موضوعية: Medicine, Cell Biology, Neuroscience, Physiology, Biotechnology, Mental Health, brain amyloid deposition, BAS use, cohort study, brain amyloid accumulation, WML, ROSMAP, brain BA receptor gene expression, serum concentrations, Religious Orders Study, HR, FDR, Clinical Practice Research Datalink, ADNI, 3- step study design, Baltimore Longitudinal Study, cholesterol catabolism, gene expression, CPRD, bile acid sequestrants, serum concentrations CA, 7α- OHC, Bile acid synthesis, CON, pharmacoepidemiologic study Background

Relation: https://figshare.com/articles/journal_contribution/Differences_in_brain_primary_BA_concentrations_between_AD_and_CON_/14687786

الاتاحة: https://doi.org/10.1371/journal.pmed.1003615.s011

المؤلفون: Vijay R. Varma (4797432), Youjin Wang (10884494), Yang An (326217), Sudhir Varma (56982), Murat Bilgel (6066809), Jimit Doshi (643398), Cristina Legido-Quigley (718909), João C. Delgado (10884497), Anup M. Oommen (4797435), Jackson A. Roberts (10884500), Dean F. Wong (672684), Christos Davatzikos (280898), Susan M. Resnick (8052875), Juan C. Troncoso (225906), Olga Pletnikova (225888), Richard O’Brien (3850429), Eelko Hak (217714), Brenda N. Baak (10884503), Ruth Pfeiffer (36526), Priyanka Baloni (2920530), Siamak Mohmoudiandehkordi (10884506), Kwangsik Nho (114023), Rima Kaddurah-Daouk (152187), David A. Bennett (229710), Shahinaz M. Gadalla (10011616), Madhav Thambisetty (133912)

مصطلحات موضوعية: Medicine, Cell Biology, Neuroscience, Physiology, Biotechnology, Mental Health, brain amyloid deposition, BAS use, cohort study, brain amyloid accumulation, WML, ROSMAP, brain BA receptor gene expression, serum concentrations, Religious Orders Study, HR, FDR, Clinical Practice Research Datalink, ADNI, 3- step study design, Baltimore Longitudinal Study, cholesterol catabolism, gene expression, CPRD, bile acid sequestrants, serum concentrations CA, 7α- OHC, Bile acid synthesis, CON, pharmacoepidemiologic study Background

Relation: https://figshare.com/articles/journal_contribution/Demographic_characteristics_of_BLSA_autopsy_sample_/14687783

الاتاحة: https://doi.org/10.1371/journal.pmed.1003615.s010

المؤلفون: Liu Shi (1952005), Noel J. Buckley (11163825), Isabelle Bos (4724580), Sebastiaan Engelborghs (3523691), Kristel Sleegers (326757), Giovanni B. Frisoni (8983100), Anders Wallin (491236), Alberto Lléo (11163828), Julius Popp (3933992), Pablo Martinez-Lage (5489750), Cristina Legido-Quigley (718909), Frederik Barkhof (146873), Henrik Zetterberg (144718), Pieter Jelle Visser (7545980), Lars Bertram (28887), Simon Lovestone (84515), Alejo J. Nevado-Holgado (8138193)

مصطلحات موضوعية: Neuroscience, Pathology, Health Care, Psychiatry (incl. Psychotherapy), Clinical Sciences not elsewhere classified, Central Nervous System, Aged Care Nursing, Aged Health Care, Protein Trafficking, Alzheimer’s disease (AD), diagnosis, blood biomarkers, meta-analysis, proteomic

Relation: https://figshare.com/articles/dataset/Table_1_Plasma_Proteomic_Biomarkers_Relating_to_Alzheimer_s_Disease_A_Meta-Analysis_Based_on_Our_Own_Studies_DOCX/15027828

الاتاحة: https://doi.org/10.3389/fnagi.2021.712545.s001

المؤلفون: Vijay R. Varma (4797432), Youjin Wang (10884494), Yang An (326217), Sudhir Varma (56982), Murat Bilgel (6066809), Jimit Doshi (643398), Cristina Legido-Quigley (718909), João C. Delgado (10884497), Anup M. Oommen (4797435), Jackson A. Roberts (10884500), Dean F. Wong (672684), Christos Davatzikos (280898), Susan M. Resnick (8052875), Juan C. Troncoso (225906), Olga Pletnikova (225888), Richard O’Brien (3850429), Eelko Hak (217714), Brenda N. Baak (10884503), Ruth Pfeiffer (36526), Priyanka Baloni (2920530), Siamak Mohmoudiandehkordi (10884506), Kwangsik Nho (114023), Rima Kaddurah-Daouk (152187), David A. Bennett (229710), Shahinaz M. Gadalla (10011616), Madhav Thambisetty (133912)

مصطلحات موضوعية: Medicine, Cell Biology, Neuroscience, Physiology, Biotechnology, Mental Health, brain amyloid deposition, BAS use, cohort study, brain amyloid accumulation, WML, ROSMAP, brain BA receptor gene expression, serum concentrations, Religious Orders Study, HR, FDR, Clinical Practice Research Datalink, ADNI, 3- step study design, Baltimore Longitudinal Study, cholesterol catabolism, gene expression, CPRD, bile acid sequestrants, serum concentrations CA, 7α- OHC, Bile acid synthesis, CON, pharmacoepidemiologic study Background

Relation: https://figshare.com/articles/figure/Catabolism_of_cholesterol_into_primary_BAs_/14687756

الاتاحة: https://doi.org/10.1371/journal.pmed.1003615.s001

المؤلفون: Vijay R. Varma (4797432), Youjin Wang (10884494), Yang An (326217), Sudhir Varma (56982), Murat Bilgel (6066809), Jimit Doshi (643398), Cristina Legido-Quigley (718909), João C. Delgado (10884497), Anup M. Oommen (4797435), Jackson A. Roberts (10884500), Dean F. Wong (672684), Christos Davatzikos (280898), Susan M. Resnick (8052875), Juan C. Troncoso (225906), Olga Pletnikova (225888), Richard O’Brien (3850429), Eelko Hak (217714), Brenda N. Baak (10884503), Ruth Pfeiffer (36526), Priyanka Baloni (2920530), Siamak Mohmoudiandehkordi (10884506), Kwangsik Nho (114023), Rima Kaddurah-Daouk (152187), David A. Bennett (229710), Shahinaz M. Gadalla (10011616), Madhav Thambisetty (133912)

مصطلحات موضوعية: Medicine, Cell Biology, Neuroscience, Physiology, Biotechnology, Mental Health, brain amyloid deposition, BAS use, cohort study, brain amyloid accumulation, WML, ROSMAP, brain BA receptor gene expression, serum concentrations, Religious Orders Study, HR, FDR, Clinical Practice Research Datalink, ADNI, 3- step study design, Baltimore Longitudinal Study, cholesterol catabolism, gene expression, CPRD, bile acid sequestrants, serum concentrations CA, 7α- OHC, Bile acid synthesis, CON, pharmacoepidemiologic study Background

Relation: https://figshare.com/articles/figure/Association_between_serum_7_-OHC_concentration_and_brain_amyloid-_burden_in_amyloid_ve_individuals_/14687798

الاتاحة: https://doi.org/10.1371/journal.pmed.1003615.g002

المؤلفون: Vijay R. Varma (4797432), Youjin Wang (10884494), Yang An (326217), Sudhir Varma (56982), Murat Bilgel (6066809), Jimit Doshi (643398), Cristina Legido-Quigley (718909), João C. Delgado (10884497), Anup M. Oommen (4797435), Jackson A. Roberts (10884500), Dean F. Wong (672684), Christos Davatzikos (280898), Susan M. Resnick (8052875), Juan C. Troncoso (225906), Olga Pletnikova (225888), Richard O’Brien (3850429), Eelko Hak (217714), Brenda N. Baak (10884503), Ruth Pfeiffer (36526), Priyanka Baloni (2920530), Siamak Mohmoudiandehkordi (10884506), Kwangsik Nho (114023), Rima Kaddurah-Daouk (152187), David A. Bennett (229710), Shahinaz M. Gadalla (10011616), Madhav Thambisetty (133912)

مصطلحات موضوعية: Medicine, Cell Biology, Neuroscience, Physiology, Biotechnology, Mental Health, brain amyloid deposition, BAS use, cohort study, brain amyloid accumulation, WML, ROSMAP, brain BA receptor gene expression, serum concentrations, Religious Orders Study, HR, FDR, Clinical Practice Research Datalink, ADNI, 3- step study design, Baltimore Longitudinal Study, cholesterol catabolism, gene expression, CPRD, bile acid sequestrants, serum concentrations CA, 7α- OHC, Bile acid synthesis, CON, pharmacoepidemiologic study Background

Relation: https://figshare.com/articles/dataset/Differences_in_brain_BA_receptor_gene_expression_including_receptors_involved_in_BA_homeostasis_in_AD_compared_to_CON_/14687792

الاتاحة: https://doi.org/10.1371/journal.pmed.1003615.s012

المؤلفون: Vijay R. Varma (4797432), Youjin Wang (10884494), Yang An (326217), Sudhir Varma (56982), Murat Bilgel (6066809), Jimit Doshi (643398), Cristina Legido-Quigley (718909), João C. Delgado (10884497), Anup M. Oommen (4797435), Jackson A. Roberts (10884500), Dean F. Wong (672684), Christos Davatzikos (280898), Susan M. Resnick (8052875), Juan C. Troncoso (225906), Olga Pletnikova (225888), Richard O’Brien (3850429), Eelko Hak (217714), Brenda N. Baak (10884503), Ruth Pfeiffer (36526), Priyanka Baloni (2920530), Siamak Mohmoudiandehkordi (10884506), Kwangsik Nho (114023), Rima Kaddurah-Daouk (152187), David A. Bennett (229710), Shahinaz M. Gadalla (10011616), Madhav Thambisetty (133912)

مصطلحات موضوعية: Medicine, Cell Biology, Neuroscience, Physiology, Biotechnology, Mental Health, brain amyloid deposition, BAS use, cohort study, brain amyloid accumulation, WML, ROSMAP, brain BA receptor gene expression, serum concentrations, Religious Orders Study, HR, FDR, Clinical Practice Research Datalink, ADNI, 3- step study design, Baltimore Longitudinal Study, cholesterol catabolism, gene expression, CPRD, bile acid sequestrants, serum concentrations CA, 7α- OHC, Bile acid synthesis, CON, pharmacoepidemiologic study Background

Relation: https://figshare.com/articles/dataset/Associations_between_serum_metabolite_concentrations_and_brain_amyloid-_deposition_rates_of_brain_atrophy_and_longitudinal_changes_in_global_brain_WML_burden_BLSA_/14687807

الاتاحة: https://doi.org/10.1371/journal.pmed.1003615.t001

المؤلفون: Vijay R. Varma (4797432), Youjin Wang (10884494), Yang An (326217), Sudhir Varma (56982), Murat Bilgel (6066809), Jimit Doshi (643398), Cristina Legido-Quigley (718909), João C. Delgado (10884497), Anup M. Oommen (4797435), Jackson A. Roberts (10884500), Dean F. Wong (672684), Christos Davatzikos (280898), Susan M. Resnick (8052875), Juan C. Troncoso (225906), Olga Pletnikova (225888), Richard O’Brien (3850429), Eelko Hak (217714), Brenda N. Baak (10884503), Ruth Pfeiffer (36526), Priyanka Baloni (2920530), Siamak Mohmoudiandehkordi (10884506), Kwangsik Nho (114023), Rima Kaddurah-Daouk (152187), David A. Bennett (229710), Shahinaz M. Gadalla (10011616), Madhav Thambisetty (133912)

مصطلحات موضوعية: Medicine, Cell Biology, Neuroscience, Physiology, Biotechnology, Mental Health, brain amyloid deposition, BAS use, cohort study, brain amyloid accumulation, WML, ROSMAP, brain BA receptor gene expression, serum concentrations, Religious Orders Study, HR, FDR, Clinical Practice Research Datalink, ADNI, 3- step study design, Baltimore Longitudinal Study, cholesterol catabolism, gene expression, CPRD, bile acid sequestrants, serum concentrations CA, 7α- OHC, Bile acid synthesis, CON, pharmacoepidemiologic study Background

Relation: https://figshare.com/articles/figure/Differences_in_brain_primary_BA_concentrations_between_AD_and_CON_/14687801

الاتاحة: https://doi.org/10.1371/journal.pmed.1003615.g003

المؤلفون: Vijay R. Varma (4797432), Youjin Wang (10884494), Yang An (326217), Sudhir Varma (56982), Murat Bilgel (6066809), Jimit Doshi (643398), Cristina Legido-Quigley (718909), João C. Delgado (10884497), Anup M. Oommen (4797435), Jackson A. Roberts (10884500), Dean F. Wong (672684), Christos Davatzikos (280898), Susan M. Resnick (8052875), Juan C. Troncoso (225906), Olga Pletnikova (225888), Richard O’Brien (3850429), Eelko Hak (217714), Brenda N. Baak (10884503), Ruth Pfeiffer (36526), Priyanka Baloni (2920530), Siamak Mohmoudiandehkordi (10884506), Kwangsik Nho (114023), Rima Kaddurah-Daouk (152187), David A. Bennett (229710), Shahinaz M. Gadalla (10011616), Madhav Thambisetty (133912)

مصطلحات موضوعية: Medicine, Cell Biology, Neuroscience, Physiology, Biotechnology, Mental Health, brain amyloid deposition, BAS use, cohort study, brain amyloid accumulation, WML, ROSMAP, brain BA receptor gene expression, serum concentrations, Religious Orders Study, HR, FDR, Clinical Practice Research Datalink, ADNI, 3- step study design, Baltimore Longitudinal Study, cholesterol catabolism, gene expression, CPRD, bile acid sequestrants, serum concentrations CA, 7α- OHC, Bile acid synthesis, CON, pharmacoepidemiologic study Background

Relation: https://figshare.com/articles/dataset/Association_between_BAS_use_and_the_risk_of_dementia_in_individuals_who_received_at_least_two_BAS_or_LMT_prescriptions_with_at_least_one_year_of_follow-up_after_second_prescription_/14687813

الاتاحة: https://doi.org/10.1371/journal.pmed.1003615.t003

المؤلفون: Vijay R. Varma (4797432), Youjin Wang (10884494), Yang An (326217), Sudhir Varma (56982), Murat Bilgel (6066809), Jimit Doshi (643398), Cristina Legido-Quigley (718909), João C. Delgado (10884497), Anup M. Oommen (4797435), Jackson A. Roberts (10884500), Dean F. Wong (672684), Christos Davatzikos (280898), Susan M. Resnick (8052875), Juan C. Troncoso (225906), Olga Pletnikova (225888), Richard O’Brien (3850429), Eelko Hak (217714), Brenda N. Baak (10884503), Ruth Pfeiffer (36526), Priyanka Baloni (2920530), Siamak Mohmoudiandehkordi (10884506), Kwangsik Nho (114023), Rima Kaddurah-Daouk (152187), David A. Bennett (229710), Shahinaz M. Gadalla (10011616), Madhav Thambisetty (133912)

مصطلحات موضوعية: Medicine, Cell Biology, Neuroscience, Physiology, Biotechnology, Mental Health, brain amyloid deposition, BAS use, cohort study, brain amyloid accumulation, WML, ROSMAP, brain BA receptor gene expression, serum concentrations, Religious Orders Study, HR, FDR, Clinical Practice Research Datalink, ADNI, 3- step study design, Baltimore Longitudinal Study, cholesterol catabolism, gene expression, CPRD, bile acid sequestrants, serum concentrations CA, 7α- OHC, Bile acid synthesis, CON, pharmacoepidemiologic study Background

Relation: https://figshare.com/articles/figure/Differences_in_brain_BA_receptor_gene_expression_between_AD_and_CON_/14687804

الاتاحة: https://doi.org/10.1371/journal.pmed.1003615.g004

المؤلفون: Vijay R. Varma (4797432), Youjin Wang (10884494), Yang An (326217), Sudhir Varma (56982), Murat Bilgel (6066809), Jimit Doshi (643398), Cristina Legido-Quigley (718909), João C. Delgado (10884497), Anup M. Oommen (4797435), Jackson A. Roberts (10884500), Dean F. Wong (672684), Christos Davatzikos (280898), Susan M. Resnick (8052875), Juan C. Troncoso (225906), Olga Pletnikova (225888), Richard O’Brien (3850429), Eelko Hak (217714), Brenda N. Baak (10884503), Ruth Pfeiffer (36526), Priyanka Baloni (2920530), Siamak Mohmoudiandehkordi (10884506), Kwangsik Nho (114023), Rima Kaddurah-Daouk (152187), David A. Bennett (229710), Shahinaz M. Gadalla (10011616), Madhav Thambisetty (133912)

مصطلحات موضوعية: Medicine, Cell Biology, Neuroscience, Physiology, Biotechnology, Mental Health, brain amyloid deposition, BAS use, cohort study, brain amyloid accumulation, WML, ROSMAP, brain BA receptor gene expression, serum concentrations, Religious Orders Study, HR, FDR, Clinical Practice Research Datalink, ADNI, 3- step study design, Baltimore Longitudinal Study, cholesterol catabolism, gene expression, CPRD, bile acid sequestrants, serum concentrations CA, 7α- OHC, Bile acid synthesis, CON, pharmacoepidemiologic study Background

Relation: https://figshare.com/articles/figure/Flowchart_of_study_participants_included_in_the_CPRD_analyses_/14687795

الاتاحة: https://doi.org/10.1371/journal.pmed.1003615.g001

المؤلفون: Vijay R. Varma (4797432), Youjin Wang (10884494), Yang An (326217), Sudhir Varma (56982), Murat Bilgel (6066809), Jimit Doshi (643398), Cristina Legido-Quigley (718909), João C. Delgado (10884497), Anup M. Oommen (4797435), Jackson A. Roberts (10884500), Dean F. Wong (672684), Christos Davatzikos (280898), Susan M. Resnick (8052875), Juan C. Troncoso (225906), Olga Pletnikova (225888), Richard O’Brien (3850429), Eelko Hak (217714), Brenda N. Baak (10884503), Ruth Pfeiffer (36526), Priyanka Baloni (2920530), Siamak Mohmoudiandehkordi (10884506), Kwangsik Nho (114023), Rima Kaddurah-Daouk (152187), David A. Bennett (229710), Shahinaz M. Gadalla (10011616), Madhav Thambisetty (133912)

مصطلحات موضوعية: Medicine, Cell Biology, Neuroscience, Physiology, Biotechnology, Mental Health, brain amyloid deposition, BAS use, cohort study, brain amyloid accumulation, WML, ROSMAP, brain BA receptor gene expression, serum concentrations, Religious Orders Study, HR, FDR, Clinical Practice Research Datalink, ADNI, 3- step study design, Baltimore Longitudinal Study, cholesterol catabolism, gene expression, CPRD, bile acid sequestrants, serum concentrations CA, 7α- OHC, Bile acid synthesis, CON, pharmacoepidemiologic study Background

Relation: https://figshare.com/articles/dataset/Associations_between_serum_metabolite_concentrations_and_rates_of_brain_atrophy_and_longitudinal_changes_in_global_brain_WML_burden_ADNI_/14687810

الاتاحة: https://doi.org/10.1371/journal.pmed.1003615.t002