المؤلفون: David E. Dawe, Rebekah Rittberg, Iqra Syed, Mary Kate Shanahan, Daniel Moldaver, Oliver Bucher, Katie Galloway, Kayla Reynolds, James T. Paul, Craig Harlos, Julian O. Kim, Shantanu Banerji

المصدر: Frontiers in Oncology, Vol 13 (2023)

مصطلحات موضوعية: small-cell lung cancer, limited-stage, performance status, real world, long-term survival, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.1191920/full; https://doaj.org/toc/2234-943X

URL الوصول: https://doaj.org/article/742802ccdef840f4897b65a493687d65

المؤلفون: David E. Dawe, Rebekah Rittberg, Iqra Syed, Mary Kate Shanahan, Daniel Moldaver, Oliver Bucher, Katie Galloway, Kayla Reynolds, James T. Paul, Craig Harlos, Julian O. Kim, Shantanu Banerji

المصدر: Frontiers in Oncology, Vol 13 (2023)

مصطلحات موضوعية: radiotherapy (RT), small cell lung cancer (SCLC), extensive stage (ES), performance status (ECOG-PS), real world, long-term survival, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.1191855/full; https://doaj.org/toc/2234-943X

URL الوصول: https://doaj.org/article/d1510321bbbe4dc89a3a88e1c924f9d4

المؤلفون: Shantanu Banerji, Daniel E. Meyers, Craig Harlos, David E. Dawe

المصدر: Current Oncology, Vol 28, Iss 6, Pp 4542-4551 (2021)

مصطلحات موضوعية: immunotherapy, mesothelioma, nivolumab, ipilimumab, pembrolizumab, cell therapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1718-7729/28/6/385; https://doaj.org/toc/1198-0052; https://doaj.org/toc/1718-7729

URL الوصول: https://doaj.org/article/0e809a0640d94465843efc77da7bb2b8

المؤلفون: Rebekah Rittberg, Craig Harlos, Heidi Rothenmund, Anirban Das, Uri Tabori, Namita Sinha, Harminder Singh, Bernie Chodirker, Christina A. Kim

المصدر: Current Oncology, Vol 28, Iss 1, Pp 757-766 (2021)

مصطلحات موضوعية: constitutional mismatch repair deficiency, CMMRD, immunotherapy, adjuvant therapy, checkpoint inhibitors, screening, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1718-7729/28/1/74; https://doaj.org/toc/1198-0052; https://doaj.org/toc/1718-7729

URL الوصول: https://doaj.org/article/cff417ce10f14a3ba83db4cc1bf154eb

المؤلفون: Lee Yi Yen, Melyssa Aronson, Carol J. Swallow, Cynthia Hawkins, Lara Reichman, Rebecca C. Luiten, Sumita Roy, Michal Zapotocky, Patrick Tomboc, Christian Kratz, Michael Osborn, Junne Kamihara, Ayse Bahar Ercan, Jamie L. Maciaszek, Vanessa Bianchi, Benjamin Oshrine, Hagit N. Baris, Ossama M. Maher, Mohsin Rashid, Sara Rhode, Sharon Gardner, Annika Bronsema, David S. Ziegler, An Van Damme, Monica Newmark, Mithra Ghalibafian, Heather Hampel, Jordan R. Hansford, Vahid Fallah Azad, Michael P. Link, Simon C. Ling, Marc Remke, Shayna Zelcer, Deborah T. Blumenthal, Isabelle Scheers, Rebecca Loret De Mola, Syed Ahmer Hamid, Vanan MagimairajanIssai, Kim E. Nichols, Saunders Hsu, Catherine Goudie, Naureen Mushtaq, Ira Winer, Abeer Al-Battashi, Garth Nicholas, Roula Farah, Kami Wolfe Schneider, Rejin Kebudi, Jan Rapp, Gregory Thomas, Helen Toledano, Alvaro Lassaletta, Anne Bendel, Jeffrey Knipstein, Musa Alharbi, Gadi Abebe-Campino, Rose B. McGee, Anirban Das, Uri Tabori, Donald Basel, Alyssa Reddy, Melissa Edwards, Scott Lindhorst, Craig Harlos, Bailey Gallinger, Elizabeth Cairney, Anita Villani, Valerie Larouche, Rachel Pearlman, Maude Blundell, Gary Mason, David Sumerauer, Magnus Sabel, Aghiad Chamdin, Leslie Taylor, David Malkin, William D. Foulkes, Maura Massimino, Catherine Gilpin, Eric Bouffet, Miriam Bornhorst, Carol Durno, Enrico Opocher, Nobuko Hijiya, Zehavit Frenkel, David Samuel, Michal Lurye, Stefanie Zimmermann, Shani Caspi, Stefano Chiaravalli, David Gass, Eshetu G. Atenafu, Shlomi Constantini, Shay Ben-Shachar, Michal Yalon, Rina Dvir, Daniel Pettee, Bruce Crooks, Santanu Sen, Carl Koschmann, Raymond Bedgood, Theodore Nicolaides, Duncan Stearns, Yael Goldberg, Melissa Galati, Gabriel Robbins

المساهمون: UCL - (SLuc) Service de gastro-entérologie et hépatologie pédiatrique, UCL - SSS/IREC/PEDI - Pôle de Pédiatrie

المصدر: Paediatrics Publications
Journal of Clinical Oncology, Vol. 39, no.25, p. 2779-2790 (2021)

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Adolescent, MEDLINE, DNA Mismatch Repair, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Neoplastic Syndromes, Hereditary, Internal medicine, medicine, Humans, Prospective Studies, Child, Early Detection of Cancer, Hematology, Brain Neoplasms, business.industry, Cancer predisposition, Prognosis, United States, Survival Rate, DNA Repair Enzymes, 030104 developmental biology, Survival benefit, Child, Preschool, Population Surveillance, 030220 oncology & carcinogenesis, MISMATCH REPAIR DEFICIENCY, Female, Colorectal Neoplasms, business, Follow-Up Studies

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc31eca9b2efe8b55ac14084ca85e170
https://doi.org/10.1200/jco.20.02636

المؤلفون: David E. Dawe, Rebekah Rittberg, Iqra Syed, Mary Kate Shanahan, Daniel Moldaver, Oliver Bucher, Katie Galloway, Kayla Reynolds, James T. Paul, Craig Harlos, Julian O. Kim, Shantanu Banerji

مصطلحات موضوعية: Cancer, Cancer Cell Biology, Cancer Diagnosis, Cancer Genetics, Cancer Therapy (excl. Chemotherapy and Radiation Therapy), Chemotherapy, Haematological Tumours, Molecular Targets, Radiation Therapy, Solid Tumours, Oncology and Carcinogenesis not elsewhere classified, radiotherapy (RT), small cell lung cancer (SCLC), extensive stage (ES), performance status (ECOG-PS), real world, long-term survival, overall survival (OS)

Relation: https://figshare.com/articles/dataset/Table_1_Real-world_predictors_of_survival_in_patients_with_extensive-stage_small-cell_lung_cancer_in_Manitoba_Canada_a_retrospective_cohort_study_docx/24155574

الاتاحة: https://doi.org/10.3389/fonc.2023.1191855.s001
https://figshare.com/articles/dataset/Table_1_Real-world_predictors_of_survival_in_patients_with_extensive-stage_small-cell_lung_cancer_in_Manitoba_Canada_a_retrospective_cohort_study_docx/24155574

المؤلفون: Harminder Singh, B. N. Chodirker, Craig Harlos, Christina Kim, Rebekah Rittberg, Namita Sinha, Anirban Das, Uri Tabori, Heidi Rothenmund

المصدر: Current Oncology
Current Oncology, Vol 28, Iss 74, Pp 757-766 (2021)

مصطلحات موضوعية: 0301 basic medicine, tumor mutational burden, medicine.medical_treatment, Case Report, 03 medical and health sciences, 0302 clinical medicine, Germline mutation, Adjuvant therapy, PMS2, constitutional mismatch repair deficiency, Medicine, RC254-282, business.industry, screening, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, adjuvant therapy, Immunotherapy, medicine.disease, Immune checkpoint, CMMRD, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer research, surveillance, Adenocarcinoma, DNA mismatch repair, immunotherapy, business, checkpoint inhibitors, Anaplastic astrocytoma

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef20cb0351428b1f0b8c763abfe8bd91
http://europepmc.org/articles/PMC7985791

المؤلفون: Roger Tsang, Samuel Weiss, Martin Smoragiewicz, Craig Harlos, Sarah Lapointe, Dongsheng Tu, Warren Mason, Joana Sederias, H. Artee Luchman, Lesley Seymour, Mary MacNeil, John P. Rossiter

المصدر: Investigational New Drugs. 38:1137-1144

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, medicine.medical_specialty, Maximum Tolerated Dose, Morpholines, Antineoplastic Agents, Mechanistic Target of Rapamycin Complex 2, mTORC1, Mechanistic Target of Rapamycin Complex 1, 03 medical and health sciences, 0302 clinical medicine, Glioma, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Temozolomide, medicine, Humans, Pharmacology (medical), Adverse effect, PI3K/AKT/mTOR pathway, Aged, Pharmacology, Brain Neoplasms, business.industry, Cancer, Middle Aged, medicine.disease, Rash, Clinical trial, Pyrimidines, 030104 developmental biology, 030220 oncology & carcinogenesis, Benzamides, Female, medicine.symptom, Glioblastoma, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::678839eecf5bfda2e7dc8aea466ef0af
https://doi.org/10.1007/s10637-019-00875-4

المؤلفون: Danielle Desautels, Craig Harlos, Piotr Czaykowski

المصدر: Journal of Carcinogenesis, Vol 13, Iss 1, Pp 13-13 (2014)

مصطلحات موضوعية: Colorectal cancer, esophagogastric cancer, precision therapy, targeted therapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

Relation: http://www.carcinogenesis.com/article.asp?issn=1477-3163;year=2014;volume=13;issue=1;spage=13;epage=13;aulast=Desautels; https://doaj.org/toc/1477-3163; https://doaj.org/article/a7cf901abf454a0685d5bbdcf6fcf69f

الاتاحة: https://doi.org/10.4103/1477-3163.145609
https://doaj.org/article/a7cf901abf454a0685d5bbdcf6fcf69f

المؤلفون: Rosalyn A. Juergens, Craig Harlos, David E. Dawe

المصدر: Curr Oncol

مصطلحات موضوعية: Oncology, medicine.medical_specialty, Lung Neoplasms, medicine.medical_treatment, Treatment of lung cancer, Review Article, Systemic therapy, 03 medical and health sciences, 0302 clinical medicine, Immune system, Internal medicine, PD-L1, medicine, Humans, In patient, 030212 general & internal medicine, Lung cancer, biology, business.industry, Immunotherapy, medicine.disease, respiratory tract diseases, 030220 oncology & carcinogenesis, biology.protein, business, Chemoradiotherapy

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f5bd6ad836f79df52f34fae8b888255
https://pubmed.ncbi.nlm.nih.gov/32368177

المؤلفون: Laurel Grant, Gefei Qing, David E. Dawe, Shantanu Banerji, Anne Blanchard, Marshall Pitz, Leigh C. Murphy, Carla Penner, Yvonne Myal, Zoann Nugent, Craig Harlos

المصدر: Hormones and Cancer. 9:288-294

مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, Cancer Research, medicine.medical_specialty, Lung Neoplasms, medicine.drug_class, Endocrinology, Diabetes and Metabolism, Disease-Free Survival, 03 medical and health sciences, 0302 clinical medicine, Endocrinology, Carcinoma, Non-Small-Cell Lung, Internal medicine, Biomarkers, Tumor, medicine, Overall survival, Humans, Lung cancer, Aged, Endocrine and Autonomic Systems, business.industry, Hazard ratio, Middle Aged, Prognosis, medicine.disease, Androgen receptor, Ki-67 Antigen, 030104 developmental biology, Receptors, Androgen, Estrogen, 030220 oncology & carcinogenesis, Adenocarcinoma, Immunohistochemistry, Female, Non small cell, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bed03360aded323b3f2391ef3e103678
https://doi.org/10.1007/s12672-018-0336-7

المؤلفون: Forough Khadem, Sabine Hombach-Klonisch, Emilia Wiechec, Zahra Sepehri, Maryam Mehrpour, Adrienne M. Gorman, Craig Harlos, Reyhane Hoshyar, Mohsen Akbari, Shahla Shojaei, Afshin Samali, Sudharsana R. Ande, Krzysztof Siemianowicz, Amir Seyfoori, Ahmed Hamaï, Saeid Ghavami, Wirginia Likus, Thomas Klonisch, Marshall Pitz, Brian Toyota

المصدر: Pharmacology & Therapeutics. 184:13-41

مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, medicine.medical_treatment, Brain tumor, Apoptosis, Models, Biological, 03 medical and health sciences, 0302 clinical medicine, Glioma, Autophagy, Temozolomide, medicine, Animals, Humans, Pharmacology (medical), Pharmacology, Chemotherapy, Brain Neoplasms, business.industry, medicine.disease, 3. Good health, 030104 developmental biology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Neoplastic Stem Cells, Unfolded Protein Response, Cancer research, Unfolded protein response, Stem cell, Glioblastoma, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0305a45080143ed701ce9f525bec715
https://doi.org/10.1016/j.pharmthera.2017.10.017

المؤلفون: Andrea Lo, Gelareh Zadeh, David B. Shultz, Barbara-Ann Millar, Paul Kongkham, Warren P. Mason, Alejandro Berlin, Fabio Y. Moraes, Erin R. Morgan, Normand Laperriere, Catherine Maurice, Mark Bernstein, Craig Harlos

المصدر: Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques. 45:199-205

مصطلحات موضوعية: Male, Aging, medicine.medical_specialty, medicine.medical_treatment, Population, Antineoplastic Agents, Kaplan-Meier Estimate, 03 medical and health sciences, 0302 clinical medicine, Patient-Centered Care, Biopsy, medicine, Humans, education, Retrospective Studies, Aged, 80 and over, education.field_of_study, Temozolomide, Radiotherapy, medicine.diagnostic_test, Performance status, Brain Neoplasms, business.industry, Disease Management, General Medicine, Oldest old, medicine.disease, Combined Modality Therapy, Confidence interval, Surgery, Radiation therapy, Treatment Outcome, Neurology, 030220 oncology & carcinogenesis, Disease Progression, Female, Neurology (clinical), Glioblastoma, business, 030217 neurology & neurosurgery, Follow-Up Studies, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee4e3de5c0197be4cf9454f6d35780ca
https://doi.org/10.1017/cjn.2017.278

المؤلفون: Scott Lindhorst, Jan Rapp, Deborah T. Blumenthal, Carl Koschmann, Mithra Ghalibafian, Rebecca Loret De Mola, Daniel Pettee, Garth Nicholas, Roula Farah, Raymond Bedgood, Aghiad Chamdin, Donald Basel, Valerie Larouche, Michal Yalon, Michal Lurye, Monica Newmark, Rachel Pearlman, Theodore Nicolaides, William D. Foulkes, Eric Bouffet, Shlomi Constantini, Shayna Zelcer, Maura Massimino, Duncan Stearns, Enrico Opocher, Saunders Hsu, Gabriel Robbins, Michael P. Link, Naureen Mushtaq, Ira Winer, Alyssa Reddy, Ayse Bahar Ercan, Rina Dvir, Zehavit Frenkel, Rebecca C. Luiten, An Van Damme, Miriam Bornhorst, Michal Zapotocky, Syed Ahmer Hamid, Sharon Gardner, Alvaro Lassaletta, Catherine Goudie, Melissa Edwards, Carol Durno, David Samuel, Anne Bendel, Mohsin Rashid, Kim E. Nichols, Sara Carroll, Junne Kamihara, Vahid Fallah Azad, Melyssa Aronson, Craig Harlos, Patrick Tomboc, Jordan R. Hansford, Vanessa Bianchi, Santanu Sen, Michael Osborn, Jamie L. Maciaszek, Benjamin Oshrine, Cathy Gilpin, Isabelle Scheers, Abeer Al-Battashi, David S. Ziegler, Marc Remke, Jeffrey Knipstein, Anirban Das, Uri Tabori, Stefano Chiaravalli, Carol J. Swallow, Magnus Sabel, Ossama M. Maher, Annika Bronsema, Stefanie Zimmerman, Lee Yi Yen, Lara Reichman, Simon C. Ling, Vanan Magimairajan, David Sumerauer, Nobuko Hijiya, Helen Toledano, Musa Alharbi, Leslie Taylor, Elizabeth Cairney

المصدر: Neuro-Oncology

مصطلحات موضوعية: Medulloblastoma, Oncology, Cancer Research, medicine.medical_specialty, business.industry, Cancer, medicine.disease, Clinical neurology, Survival benefit, Internal medicine, Glioma, medicine, MISMATCH REPAIR DEFICIENCY, AcademicSubjects/MED00300, DNA mismatch repair, AcademicSubjects/MED00310, Neurology (clinical), business, Craniopharyngioma and Rare Tumors, Glioblastoma

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06c83ff109933b99d95c03cb7d71d296
http://europepmc.org/articles/PMC7715879

المؤلفون: R Poon, P MacCrostie, Warren P. Mason, Craig Harlos, Ur Metser

المصدر: Current Oncology
Volume 26
Issue 4
Pages 4583-465

مصطلحات موضوعية: medicine.medical_specialty, Suspicious for Malignancy, medicine.diagnostic_test, business.industry, specificity, Malignancy, medicine.disease, sensitivity, Occult, Cancer registry, 03 medical and health sciences, 0302 clinical medicine, Positron emission tomography, 030220 oncology & carcinogenesis, Meta-analysis, medicine, Original Article, 030212 general & internal medicine, Tomography, Radiology, positron-emission tomography, Paraneoplastic neurologic syndrome, business, Indeterminate, malignancy

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a53dea21172be59c217f1bda2af4c41

المؤلفون: Craig Harlos, Danielle Desautels, Katarzyna J. Jerzak

المصدر: Annals of palliative medicine. 9(3)

مصطلحات موضوعية: Oncology, medicine.medical_specialty, Pathologic fracture, Bone Neoplasms, 03 medical and health sciences, 0302 clinical medicine, Osteoclast, Spinal cord compression, Internal medicine, medicine, Tumor Microenvironment, Humans, 030212 general & internal medicine, Dosing, Multiple myeloma, Advanced and Specialized Nursing, Diphosphonates, business.industry, Osteoblast, medicine.disease, Advanced cancer, Anesthesiology and Pain Medicine, Denosumab, medicine.anatomical_structure, Fractures, Spontaneous, 030220 oncology & carcinogenesis, business, Spinal Cord Compression, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af90f464adc1b2a4d790b692555bc92b
https://pubmed.ncbi.nlm.nih.gov/31500423

المؤلفون: Marshall Pitz, Rashid Ahmed, Grace Musto, Pascal Lambert, Craig Harlos

المصدر: Hormones and Cancer. 6:120-127

مصطلحات موضوعية: Adult, Male, Oncology, Cancer Research, medicine.medical_specialty, Lung Neoplasms, Antineoplastic Agents, Hormonal, medicine.drug_class, Endocrinology, Diabetes and Metabolism, Population, Kaplan-Meier Estimate, Cohort Studies, Gonadotropin-Releasing Hormone, Neoplasms, Multiple Primary, chemistry.chemical_compound, 5-alpha Reductase Inhibitors, Endocrinology, Internal medicine, Epidemiology, medicine, Humans, Registries, Lung cancer, education, Aged, Proportional Hazards Models, Retrospective Studies, Aged, 80 and over, Gynecology, education.field_of_study, Endocrine and Autonomic Systems, business.industry, Proportional hazards model, Prostatic Neoplasms, Androgen Antagonists, Retrospective cohort study, Middle Aged, medicine.disease, Androgen, Cancer registry, chemistry, Androgens, Finasteride, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9e8fdfff346dc5eec79779e3a8504c7
https://doi.org/10.1007/s12672-015-0218-1

المؤلفون: Harminder Singh, Piotr Czaykowski, Salah Mahmud, Z. Nugent, Alain A. Demers, Craig Harlos

المصدر: Current Oncology
Volume 23
Issue 6
Pages 3304-397

مصطلحات موضوعية: Gynecology, Oncology, medicine.medical_specialty, ureteric neoplasms, Proportional hazards model, Colorectal cancer, business.industry, Incidence (epidemiology), Hazard ratio, Cancer, medicine.disease, Colorectal neoplasms, Cancer registry, Internal medicine, Cohort, medicine, Original Article, second primary neoplasms, competing risks analyses, business, urinary bladder neoplasms, survivorship, Record linkage

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f47db0fd2012ce93e684f107fa8865b

المؤلفون: Piotr Czaykowski, Craig Harlos, Danielle Desautels

المصدر: Journal of Carcinogenesis
Journal of Carcinogenesis, Vol 13, Iss 1, Pp 13-13 (2014)

مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, Pathology, Bevacizumab, Colorectal cancer, medicine.drug_class, Health, Toxicology and Mutagenesis, medicine.medical_treatment, precision therapy, Review Article, Monoclonal antibody, lcsh:RC254-282, Systemic therapy, Targeted therapy, Internal medicine, medicine, Epidermal growth factor receptor, biology, business.industry, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, medicine.disease, Precision medicine, targeted therapy, esophagogastric cancer, Review article, biology.protein, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41a3b9b48e3a71cb6d652e46997768c3
http://europepmc.org/articles/PMC4258725

المؤلفون: Craig Harlos, Grace Musto, Marshall Pitz

المصدر: Journal of Clinical Oncology. 31:1597-1597

مصطلحات موضوعية: Gynecology, Oncology, Cancer Research, medicine.medical_specialty, business.industry, medicine.disease, Pathophysiology, Androgen deprivation therapy, Internal medicine, Epidemiology, Medicine, In patient, business, Lung cancer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::23cf93f979ba9a300448cec0761582cd
https://doi.org/10.1200/jco.2013.31.15_suppl.1597