نتائج البحث - "Craig Fairchild"

1

Academic Journal

EUPENIFELDIN, A NOVEL CYTOTOXIC BISTROPOLONE FROM Eupenicillium brefeldianum

المؤلفون: CRAIG FAIRCHILD, DOLORES M. PIRNIK, DONALD R. GUSTAVSON, FRIEDRICH MAYERL, JAMES A. MATSON, QI GAO, RONALD L. BERRY, STELLA HUANG, STEVEN E. KLOHR, WILLIAM C. ROSE

المصدر: The Journal of Antibiotics. 1993, 46(7):1082

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2

Supplementary Tables S1-S4 from IRS2 Copy Number Gain, KRAS and BRAF Mutation Status as Predictive Biomarkers for Response to the IGF-1R/IR Inhibitor BMS-754807 in Colorectal Cancer Cell Lines

المؤلفون: Joan M. Carboni, Jeffrey Jackson, Friedrich G. Finckenstein, Tai W. Wong, Rolf-Peter Ryseck, Craig Fairchild, Zhenhao Qi, Dharmesh Patel, John Cogswell, Warren Hurlburt, Karen A. Reeves, Stephen Hillerman, Ann Greer, Han Chang, Fei Huang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf361093d6982b4e2b58d163680e344
https://doi.org/10.1158/1535-7163.22503652.v1

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3

Supplementary Figure Legend from Sensitivity of Small Cell Lung Cancer to BET Inhibition Is Mediated by Regulation of ASCL1 Gene Expression

المؤلفون: Susan Wee, Tai Wong, Craig Fairchild, Petra Ross-Macdonald, Ashok Purandare, Liang Schweizer, Russell Peterson, Kathy Johnston, Ming Lei, Jian Cao, Heshani Desilva, Stefan Kirov, Ryan Lenhart

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::925b76df5694fd9eb1cfac9521e24646
https://doi.org/10.1158/1535-7163.22501651

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4

Supplementary Table 2 from Sensitivity of Small Cell Lung Cancer to BET Inhibition Is Mediated by Regulation of ASCL1 Gene Expression

المؤلفون: Susan Wee, Tai Wong, Craig Fairchild, Petra Ross-Macdonald, Ashok Purandare, Liang Schweizer, Russell Peterson, Kathy Johnston, Ming Lei, Jian Cao, Heshani Desilva, Stefan Kirov, Ryan Lenhart

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7facb10562e6d7eeda3f57ecf51d390b
https://doi.org/10.1158/1535-7163.22501642

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5

Supplementary Figures S1-S5 from IRS2 Copy Number Gain, KRAS and BRAF Mutation Status as Predictive Biomarkers for Response to the IGF-1R/IR Inhibitor BMS-754807 in Colorectal Cancer Cell Lines

المؤلفون: Joan M. Carboni, Jeffrey Jackson, Friedrich G. Finckenstein, Tai W. Wong, Rolf-Peter Ryseck, Craig Fairchild, Zhenhao Qi, Dharmesh Patel, John Cogswell, Warren Hurlburt, Karen A. Reeves, Stephen Hillerman, Ann Greer, Han Chang, Fei Huang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2952872ef51281f0ac1ebaa8a0d3bbc8
https://doi.org/10.1158/1535-7163.22503658.v1

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6

Supplementary Table 1 from Sensitivity of Small Cell Lung Cancer to BET Inhibition Is Mediated by Regulation of ASCL1 Gene Expression

المؤلفون: Susan Wee, Tai Wong, Craig Fairchild, Petra Ross-Macdonald, Ashok Purandare, Liang Schweizer, Russell Peterson, Kathy Johnston, Ming Lei, Jian Cao, Heshani Desilva, Stefan Kirov, Ryan Lenhart

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28c87f849fac33e449fdec8f053ea3d3
https://doi.org/10.1158/1535-7163.22501645.v1

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7

Data from Sensitivity of Small Cell Lung Cancer to BET Inhibition Is Mediated by Regulation of ASCL1 Gene Expression

المؤلفون: Susan Wee, Tai Wong, Craig Fairchild, Petra Ross-Macdonald, Ashok Purandare, Liang Schweizer, Russell Peterson, Kathy Johnston, Ming Lei, Jian Cao, Heshani Desilva, Stefan Kirov, Ryan Lenhart

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e13d258e5640d006714c350f047602ca
https://doi.org/10.1158/1535-7163.c.6536854.v1

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8

Supplementary Figures 1 through 8 from Sensitivity of Small Cell Lung Cancer to BET Inhibition Is Mediated by Regulation of ASCL1 Gene Expression

المؤلفون: Susan Wee, Tai Wong, Craig Fairchild, Petra Ross-Macdonald, Ashok Purandare, Liang Schweizer, Russell Peterson, Kathy Johnston, Ming Lei, Jian Cao, Heshani Desilva, Stefan Kirov, Ryan Lenhart

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f48394b5ceac603e4b0587b11ae1b320
https://doi.org/10.1158/1535-7163.22501648.v1

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9

Supplementary Tables 1-3, Figure Legends 1-6 from Antitumor and Antiangiogenic Activities of BMS-690514, an Inhibitor of Human EGF and VEGF Receptor Kinase Families

المؤلفون: Chiang Yu, Gregory Vite, Simone Oppenheimer, Derek Norris, Harold Malone, Anne Lewin, Daniel Kukral, Bala Krishnan, John T. Hunt, Christine Hilt, Benjamin Henley, Amy Hammell, Ashvinikumar Gavai, Brian Fink, Joseph Fargnoli, Craig Fairchild, Stuart Emanuel, Francis Y. Lee, Tai W. Wong

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6f909ef46a03d1570a27d99c5261e2b
https://doi.org/10.1158/1078-0432.22441917.v1

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10

Data from Antitumor and Antiangiogenic Activities of BMS-690514, an Inhibitor of Human EGF and VEGF Receptor Kinase Families

المؤلفون: Chiang Yu, Gregory Vite, Simone Oppenheimer, Derek Norris, Harold Malone, Anne Lewin, Daniel Kukral, Bala Krishnan, John T. Hunt, Christine Hilt, Benjamin Henley, Amy Hammell, Ashvinikumar Gavai, Brian Fink, Joseph Fargnoli, Craig Fairchild, Stuart Emanuel, Francis Y. Lee, Tai W. Wong

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33f1ae66761ffc51c82294bcb244134
https://doi.org/10.1158/1078-0432.c.6518787

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11

Supplementary Figures 1-6 from Antitumor and Antiangiogenic Activities of BMS-690514, an Inhibitor of Human EGF and VEGF Receptor Kinase Families

المؤلفون: Chiang Yu, Gregory Vite, Simone Oppenheimer, Derek Norris, Harold Malone, Anne Lewin, Daniel Kukral, Bala Krishnan, John T. Hunt, Christine Hilt, Benjamin Henley, Amy Hammell, Ashvinikumar Gavai, Brian Fink, Joseph Fargnoli, Craig Fairchild, Stuart Emanuel, Francis Y. Lee, Tai W. Wong

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10077e61e239f1a813c40834f158a23d
https://doi.org/10.1158/1078-0432.22441920

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12

Supplementary Information and Figures 1-3 from Identification of Candidate Molecular Markers Predicting Sensitivity in Solid Tumors to Dasatinib: Rationale for Patient Selection

المؤلفون: Edwin Clark, Peter Shaw, Francis Lee, Tai W. Wong, Suso Platero, Craig Fairchild, Xia Han, Karen Reeves, Fei Huang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1f4b66913786ae46ca0170c762107b4
https://doi.org/10.1158/0008-5472.22371497

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13

IRS2 Copy Number Gain, KRAS and BRAF Mutation Status as Predictive Biomarkers for Response to the IGF-1R/IR Inhibitor BMS-754807 in Colorectal Cancer Cell Lines

المؤلفون: Warren Hurlburt, Ann Greer, Tai W. Wong, Rolf-Peter Ryseck, John Cogswell, Craig Fairchild, Han Chang, Zhenhao Qi, Karen A. Reeves, Joan M. Carboni, Jeffrey R. Jackson, Stephen Hillerman, Friedrich Graf Finckenstein, Fei Huang, Dharmesh Patel

المصدر: Molecular Cancer Therapeutics. 14:620-630

مصطلحات موضوعية: Proto-Oncogene Proteins B-raf, Cancer Research, DNA Copy Number Variations, Colorectal cancer, Blotting, Western, DNA Mutational Analysis, Gene Dosage, Biology, Ligands, medicine.disease_cause, Models, Biological, Gene dosage, Receptor, IGF Type 1, Proto-Oncogene Proteins p21(ras), Growth factor receptor, Cell Line, Tumor, Proto-Oncogene Proteins, Biomarkers, Tumor, medicine, Humans, Phosphorylation, Protein kinase B, Mutation, Triazines, Gene Amplification, medicine.disease, Receptor, Insulin, Oncology, Insulin Receptor Substrate Proteins, ras Proteins, Cancer research, Pyrazoles, KRAS, Signal transduction, Colorectal Neoplasms, Insulin-Like Growth Factor Binding Protein 6, V600E

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b430c4a40209a11ce76861ec9be4f166
https://doi.org/10.1158/1535-7163.mct-14-0794-t

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14

Pharmacology of smac mimetics; chemotype differentiation based on physical association with caspase regulators and cellular transport

المؤلفون: Bryan C. Barnhart, John T. Hunt, Craig Fairchild, Joseph G. Naglich, Henry Shen, Charu Chaudhry, Randy Talbott, Marie Ortega, Robert M. Borzilleri, Ragini Vuppugalla, Thomas McDonagh, Joseph Fargnoli, Marco M. Gottardis, Gregory D. Vite

المصدر: Experimental cell research. 338(2)

مصطلحات موضوعية: ATP Binding Cassette Transporter, Subfamily B, Mice, Nude, Antineoplastic Agents, Apoptosis, Plasma protein binding, Biology, Inhibitor of apoptosis, Inhibitor of Apoptosis Proteins, Mitochondrial Proteins, Biomimetics, Cell Line, Tumor, Animals, Humans, Melanoma, Cell Proliferation, Mice, Inbred BALB C, Activator (genetics), Caspase 3, Binding protein, Intracellular Signaling Peptides and Proteins, Biological Transport, Cell Differentiation, Cell Biology, HCT116 Cells, XIAP, Protein Structure, Tertiary, Biochemistry, Female, Baculoviral IAP repeat-containing protein 3, biological phenomena, cell phenomena, and immunity, Signal transduction, Apoptosis Regulatory Proteins, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3fb4ed937d242ff03f19197c29ddcf
https://pubmed.ncbi.nlm.nih.gov/26302264

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15

Discovery of N-(2-Chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a Dual Src/Abl Kinase Inhibitor with Potent Antitumor Activity in Preclinical Assays

المصدر: Journal of Medicinal Chemistry. 47:6658-6661

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::368da0e6e3d35ffae3cb0ff13f42526f
https://doi.org/10.1021/jm049486a

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16

Novel Strategies for the Discovery of Plant-Derived Anticancer Agents

المؤلفون: Craig Fairchild, Norman R. Farnsworth, Monroe E. Wall, Steven M. Swanson, Robert Kramer, Geoffrey A. Cordell, Nicholas H. Oberlies, Gregory D. Vite, Robert A. Wild, Russell Peterson, John M. Pezzuto, A. D. Kinghorn, William C. Rose, David J. Kroll, Djaja D. Soejarto, Mansukh C. Wani

المصدر: Pharmaceutical Biology. 41:53-67

مصطلحات موضوعية: Pharmacology, Antitumor activity, Primary (chemistry), Drug discovery, business.industry, In vitro toxicology, Pharmaceutical Science, General Medicine, Biology, Biotechnology, Complementary and alternative medicine, Activity guided fractionation, Chemical diversity, Drug Discovery, Molecular Medicine, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7cfa2d66b95ccbcd61a18d7649102cde
https://doi.org/10.1080/1388020039051744

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17

Sensitivity of Small Cell Lung Cancer to BET Inhibition Is Mediated by Regulation of ASCL1 Gene Expression

المؤلفون: Stefan Kirov, Ryan Lenhart, Ming Lei, Heshani Desilva, Craig Fairchild, Kathy A. Johnston, Ashok V. Purandare, Petra Ross-Macdonald, Jian Cao, Tai W. Wong, Russell Peterson, Liang Schweizer, Susan Wee

المصدر: Molecular cancer therapeutics. 14(10)

مصطلحات موضوعية: Cancer Research, BRD4, Lung Neoplasms, Cell Survival, Gene Expression, chemical and pharmacologic phenomena, Antineoplastic Agents, Cell Cycle Proteins, Biology, BET inhibitor, chemistry.chemical_compound, Inhibitory Concentration 50, Cell Line, Tumor, Basic Helix-Loop-Helix Transcription Factors, Humans, Nuclear protein, neoplasms, Transcription factor, Cell Proliferation, Oncogene, Nuclear Proteins, hemic and immune systems, Azepines, Triazoles, Molecular biology, Small Cell Lung Carcinoma, respiratory tract diseases, Bromodomain, Gene Expression Regulation, Neoplastic, Enhancer Elements, Genetic, Oncology, chemistry, Drug Resistance, Neoplasm, Cancer research, Growth inhibition, Drug Screening Assays, Antitumor, Transcriptome, Chromatin immunoprecipitation, Protein Binding, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b9ffbd5c69e835392ee5df110748392
https://pubmed.ncbi.nlm.nih.gov/26253517

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18

Synthesis and antitumor activity of novel paclitaxel–chlorambucil hybrids

المؤلفون: Kathy A. Johnston, Mark D. Wittman, Dolatrai M. Vyas, Craig Fairchild, Francis L. Lee, John F. Kadow, William C. Rose, Byron H. Long

المصدر: Bioorganic & Medicinal Chemistry Letters. 11:811-814

مصطلحات موضوعية: Paclitaxel, Stereochemistry, medicine.medical_treatment, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Pharmacology, Biochemistry, Chemical synthesis, Inhibitory Concentration 50, Mice, chemistry.chemical_compound, immune system diseases, In vivo, hemic and lymphatic diseases, Drug Discovery, Tumor Cells, Cultured, medicine, Animals, Humans, Cytotoxicity, Antineoplastic Agents, Alkylating, Molecular Biology, Ovarian Neoplasms, Chemotherapy, Chlorambucil, Chemistry, Organic Chemistry, Sarcoma, Biological activity, Antineoplastic Agents, Phytogenic, Xenograft Model Antitumor Assays, In vitro, Disease Models, Animal, Molecular Medicine, Female, Neoplasm Transplantation, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04c769575256969c10bc56efddf3f8d4
https://doi.org/10.1016/s0960-894x(01)00067-1

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19

Preclinical antitumor activity of two novel taxanes

المؤلفون: Craig Fairchild, Francis Y. Lee, William C. Rose

المصدر: Cancer Chemotherapy and Pharmacology. 47:97-105

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f5f505a3462275b2be50f04a89b18a1
https://doi.org/10.1007/s002800000241

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20

Stereospecific synthesis of 7-deoxy-6-hydroxy paclitaxel

المؤلفون: Dolatrai M. Vyas, Byron H. Long, Thomas J. Alstadt, Kathy Johnson, Mark D. Wittman, John F. Kadow, Craig Fairchild

المصدر: Tetrahedron Letters. 40:4943-4946

مصطلحات موضوعية: Transposition (music), Germanium compounds, chemistry.chemical_compound, Stereospecificity, Paclitaxel, chemistry, Hydride, Stereochemistry, Organic Chemistry, Drug Discovery, Stereoselectivity, Biochemistry, Deoxygenation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0f4255f77511ae07ef5d94a3141b6527
https://doi.org/10.1016/s0040-4039(99)00864-3

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