المؤلفون: Krista E. Bianco, Cox Eric David, Jotham Wadsworth Coe, Michael G. Vetelino, Brian P. Boscoe, Paige Roanne Palmer Brooks

المصدر: The Journal of Organic Chemistry. 68:9964-9970

مصطلحات موضوعية: Oxidative cyclization, Reaction mechanism, Chemistry, Organic Chemistry, General Medicine, Ring (chemistry), Medicinal chemistry, Enol, Chemical synthesis, Lower temperature, Sulfone, chemistry.chemical_compound, Yield (chemistry), Alkyl substitution, Organic chemistry, Trifluoromethanesulfonate, Acetophenone

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b68eb34c6dab2cbcb0d1121d5b306925
https://doi.org/10.1021/jo0352023

المؤلفون: Maria A. Vanvolkenburg, L. D. Mcclure, Stephen J. Orena, Kim M. Andrews, Benjamin N. Rocke, Jay S. Lillquist, Judith L. Treadway, Stephen W. Wright, Zhengrong Zhao, Thanh V. Olson, Janice C. Parker, Shawn D. Doran, Walter C. Soeller, R. Kirk McPherson, Anne M. Brodeur, Cox Eric David, Carolyn B. Soglia, Shenping Liu, Mark Ammirati, Dennis E. Danley

المصدر: Bioorganicmedicinal chemistry letters. 17(20)

مصطلحات موضوعية: Models, Molecular, Pyrrolidines, Stereochemistry, Dipeptidyl Peptidase 4, Clinical Biochemistry, Pharmaceutical Science, Crystallography, X-Ray, Biochemistry, Chemical synthesis, Pyrrolidine, Dipeptidyl peptidase, chemistry.chemical_compound, Dogs, In vivo, Drug Discovery, Animals, Humans, Protease Inhibitors, Molecular Biology, chemistry.chemical_classification, Dipeptidyl-Peptidase IV Inhibitors, biology, Molecular Structure, Organic Chemistry, Stereoisomerism, Fluorine, In vitro, Rats, Enzyme, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine, Selectivity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69f927a94060b522e9278cf93b62b98b
https://pubmed.ncbi.nlm.nih.gov/17822893

المؤلفون: Joel Morris, Samit Kumar Bhattacharya, Leslie R. Pustilnik, James D. Moyer, John Charles Kath, Daniel Tyler Richter, Cox Eric David, Kris Rafidi, Chunyan Su, Matthew David Wessel, Alan M. Mathiowetz

المصدر: Biochemical and biophysical research communications. 307(2)

مصطلحات موضوعية: Models, Molecular, Receptor, ErbB-2, Recombinant Fusion Proteins, Biophysics, Protein tyrosine phosphatase, Biochemistry, Receptor tyrosine kinase, Cell Line, Substrate Specificity, Adenosine Triphosphate, Animals, Humans, Kinase activity, Enzyme Inhibitors, Phosphorylation, Molecular Biology, Aniline Compounds, Binding Sites, biology, Molecular Structure, Cell Biology, Cell biology, Protein Structure, Tertiary, ErbB Receptors, Mitogen-activated protein kinase, Drug Design, ROR1, biology.protein, Quinazolines, Janus kinase, Tyrosine kinase, Proto-oncogene tyrosine-protein kinase Src

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5aed04438e43255d21a8893e50a569a
https://pubmed.ncbi.nlm.nih.gov/12859950

المؤلفون: Janice C. Parker, Kenneth J. DiRico, Shawn D. Doran, Brian P. Boscoe, David D. Boyer, Jeffrey W. Corbett, Xiayang Qiu, Maria A. Vanvolkenburg, Cox Eric David, Mark Ammirati, Wei Song, R.K. McPherson

المصدر: Bioorganic & Medicinal Chemistry Letters. 18:2229

مصطلحات موضوعية: Dpp iv inhibitors, Chemistry, Stereochemistry, Organic Chemistry, Clinical Biochemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, Molecular Biology, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::52ddbb9bd3387c8d0170c11dddae6225
https://doi.org/10.1016/j.bmcl.2008.02.003