المؤلفون: Zecchini, V, Paupe, V, Herranz-Montoya, I, Janssen, J, Wortel, IMN, Morris, JL, Ferguson, A, Chowdury, SR, Segarra-Mondejar, M, Costa, ASH, Pereira, GC, Tronci, L, Young, T, Nikitopoulou, E, Yang, M, Bihary, D, Caicci, F, Nagashima, S, Speed, A, Bokea, K, Baig, Z, Samarajiwa, S, Tran, M, Mitchell, T, Johnson, M, Prudent, J, Frezza, C

المصدر: 506 ; 499

Relation: Nature; http://hdl.handle.net/10044/1/103316

الاتاحة: http://hdl.handle.net/10044/1/103316
https://doi.org/10.1038/s41586-023-05770-w

المؤلفون: Sciacovelli, M., Dugourd, A., Jimenez, L.V., Yang, M., Nikitopoulou, E., Costa, ASH, Tronci, L., Caraffini, V., Rodrigues, P., Schmidt, C., Ryan, D.G., Young, T., Zecchini, V.R., Rossi, S.H., Massie, C., Lohoff, C., Masid, M., Hatzimanikatis, V., Kuppe, C., Von Kriegsheim, A., Kramann, R., Gnanapragasam, V., Warren, A.Y., Stewart, G.D., Erez, A., Vanharanta, S., Saez-Rodriguez, J., Frezza, C.

المصدر: Nature communications, vol. 13, no. 1, pp. 7830

مصطلحات موضوعية: Humans, Carcinoma, Renal Cell/genetics, Amino Acids, Branched-Chain, Nitrogen, Kidney Neoplasms/genetics, Arginine/metabolism, Cell Line, Tumor

وصف الملف: application/pdf

Relation: info:eu-repo/semantics/altIdentifier/pmid/36539415; info:eu-repo/semantics/altIdentifier/eissn/2041-1723; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_F0C9789356936; https://serval.unil.ch/notice/serval:BIB_F0C978935693; https://serval.unil.ch/resource/serval:BIB_F0C978935693.P001/REF.pdf

الاتاحة: https://serval.unil.ch/notice/serval:BIB_F0C978935693
https://doi.org/10.1038/s41467-022-35036-4
https://serval.unil.ch/resource/serval:BIB_F0C978935693.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_F0C9789356936

المؤلفون: Demircioglu, F, Wang, J, Candido, J, Costa, ASH, Casado, P, de Luxan Delgado, B, Reynolds, LE, Gomez-Escudero, J, Newport, E, Rajeeve, V, Baker, A-M, Roy-Luzarraga, M, Graham, TA, Foster, J, Wang, Y, Campbell, JJ, Singh, R, Zhang, P, Schall, TJ, Balkwill, FR, Sosabowski, J, Cutillas, PR, Frezza, C, Sancho, P, Hodivala-Dilke, K

المساهمون: Baker, Ann-Marie Clare, Graham, Trevor

مصطلحات موضوعية: Animals, Breast Neoplasms, Cancer-Associated Fibroblasts, Cell Line, Tumor, Cell Proliferation, Chemokines, Female, Focal Adhesion Protein-Tyrosine Kinases, Glycolysis, Humans, Male, Metabolic Networks and Pathways, Mice, Inbred C57BL, Neoplasms, Pancreatic Neoplasms, Phosphoproteins, Stromal Cells, Survival Analysis, Xenograft Model Antitumor Assays

جغرافية الموضوع: England

وصف الملف: Electronic; application/pdf

Relation: 1290; Nature Communications, 2020, 11 (1), pp. 1290 -; https://repository.icr.ac.uk/handle/internal/5451

الاتاحة: https://doi.org/10.1038/s41467-020-15104-3
https://repository.icr.ac.uk/handle/internal/5451

المؤلفون: Dugourd, A, Kuppe, C, Sciacovelli, M, Gjerga, E, Gabor, A, Emdal, KB, Vieira, V, Bekker-Jensen, DB, Kranz, J, Bindels, Eric, Costa, ASH, Sousa, A, Beltrao, P, Rocha, M, Olsen, JV, Frezza, C, Kramann, Rafael, Saez-Rodriguez, J

المصدر: Dugourd , A , Kuppe , C , Sciacovelli , M , Gjerga , E , Gabor , A , Emdal , KB , Vieira , V , Bekker-Jensen , DB , Kranz , J , Bindels , E , Costa , ASH , Sousa , A , Beltrao , P , Rocha , M , Olsen , JV , Frezza , C , Kramann , R & Saez-Rodriguez , J 2021 , ' Causal integration of multi-omics data with prior knowledge to generate mechanistic hypotheses ' , Molecular Systems Biology , vol. 17 , no. 1 , e9730 ....

مصطلحات موضوعية: /dk/atira/pure/keywords/researchprograms/AFL001000/EMCOR01, name=EMC OR-01, /dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_being, name=SDG 3 - Good Health and Well-being

وصف الملف: application/pdf

الاتاحة: https://pure.eur.nl/en/publications/0bde4502-1907-40a6-b3a5-f1670149dba4
https://doi.org/10.15252/msb.20209730
https://pure.eur.nl/ws/files/48435220/Repub_134285_O-A.pdf
http://www.scopus.com/inward/record.url?scp=85099968883&partnerID=8YFLogxK

المؤلفون: O'Neill, JS, Hoyle, NP, Robertson, JB, Edgar, RS, Beale, AD, Peak-Chew, SY, Day, J, Costa, ASH, Frezza, C, Causton, HC

المصدر: 7269.

جغرافية الموضوع: England

Relation: Nature Communications; http://hdl.handle.net/10044/1/104005

الاتاحة: http://hdl.handle.net/10044/1/104005
https://doi.org/10.1038/s41467-021-27497-w

المؤلفون: Xu, R, Jones, W, Wilcz-Villega, E, Costa, ASH, Rajeeve, V, Bentham, RB, Bryson, K, Nagano, A, Yaman, B, Olendo Barasa, S, Wang, Y, Chelala, C, Cutillas, P, Szabadkai, G, Frezza, C, Bianchi, K

مصطلحات موضوعية: ATF4, breast cancer, IKK epsilon, mitochondrial metabolism, serine biosynthesis

Relation: EMBO REPORTS; ARTN e48260; https://qmro.qmul.ac.uk/xmlui/handle/123456789/67483

الاتاحة: https://qmro.qmul.ac.uk/xmlui/handle/123456789/67483
https://doi.org/10.15252/embr.201948260

المؤلفون: O' Neill, JS, Hoyle, NP, Robertson, JB, Edgar, RS, Beale, AD, Peak-Chew, SY, Day, J, Costa, ASH, Frezza, C, Causton, HC

المصدر: 11 ; 1

مصطلحات موضوعية: Science & Technology, Multidisciplinary Sciences, Science & Technology - Other Topics, YEAST METABOLIC CYCLE, SACCHAROMYCES-CEREVISIAE, CIRCADIAN-RHYTHM, RESPIRATORY OSCILLATIONS, KINASE, TORC1, STATE, PH, ACTIVATION, AUTOPHAGY, Bioreactors, Circadian Rhythm, Energy Metabolism, Eukaryotic Cells, Glycogen, Heat-Shock Response, Ionomycin, Mechanistic Target of Rapamycin Complex 1, Metabolomics, Molecular Chaperones, Osmolar Concentration, Osmotic Pressure, Oxygen, Protein Biosynthesis, Protein Processing, Post-Translational, Proteome

Relation: Nature Communications; http://hdl.handle.net/10044/1/87226

الاتاحة: http://hdl.handle.net/10044/1/87226
https://doi.org/10.1038/s41467-020-18330-x

المؤلفون: Behmoaras, J, Ko, J-H, Olona, A, Papathanassiu, AE, Buang, N, Park, K-S, Costa, ASH, Mauro, C

المساهمون: Medical Research Council (MRC)

مصطلحات موضوعية: BCAT1, Immunometabolism, Macrophages, Mitochondria, Redox biology, TCA cycle, 06 Biological Sciences, 11 Medical and Health Sciences, Developmental Biology

Relation: Journal of Cell Science; http://hdl.handle.net/10044/1/85078; MR/M004716/1; MR/N01121X/1; MR/V027638/1

الاتاحة: http://hdl.handle.net/10044/1/85078
https://doi.org/10.1242/jcs.247957

المؤلفون: Kohlhauer, M, Pell, VR, Burger, N, Spiroski, AM, Gruszczyk, A, Mulvey, JF, Mottahedin, Amin, Costa, ASH, Frezza, C, Ghaleh, B, Murphy, MP, Tissier, R, Krieg, T

مصطلحات موضوعية: Dimethyl malonate, Hypothermia, Ischemia, Myocardial infarction, Reperfusion, Succinate, Animals, Induced, Male, Malonates, Myocardial Reperfusion Injury, Rabbits, Random Allocation, Succinic Acid

وصف الملف: Electronic; application/pdf

Relation: https://www.repository.cam.ac.uk/handle/1810/290857

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/290857
https://doi.org/10.17863/CAM.38051

المؤلفون: Thomas, LW, Esposito, C, Stephen, JM, Costa, ASH, Frezza, C, Blacker, TS, Szabadkai, G, Ashcroft, M

المصدر: Cancer & Metabolism , 7 , Article 7. (2019)

مصطلحات موضوعية: Coiled-coil helix coiled-coil helix domain-containing protein 4 (CHCHD4), hypoxia, HIF-1α, mitochondria, respiratory chain, disulfide relay system, complex I, tumour growth, tumour metabolism

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10079105/1/s40170-019-0200-4.pdf; https://discovery.ucl.ac.uk/id/eprint/10079105/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10079105/1/s40170-019-0200-4.pdf
https://discovery.ucl.ac.uk/id/eprint/10079105/

المؤلفون: Pereira, M, Chen, T-D, Buang, N, Olona, A, Ko, J-H, Prendecki, M, Costa, ASH, Nikitopoulou, E, Tronci, L, Pusey, CD, Cook, HT, McAdoo, SP, Frezza, C, Behmoaras, J

المساهمون: Medical Research Council (MRC)

المصدر: 511.e5 ; 498

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Cell Biology, SUCCINATE-DEHYDROGENASE, CLUSTER BIOGENESIS, KEY ROLE, CELLS, MITOCHONDRIA, POLARIZATION, OXIDATION, ITACONATE, CITRATE, DAMAGE, glomerulonephritis, immunometabolism, inflammation, iron, macrophages, Animals, Humans, Male, Rats, 0601 Biochemistry and Cell Biology, 1116 Medical Physiology

Relation: Cell Reports; http://hdl.handle.net/10044/1/70660; MR/M004716/1; MR/N01121X/1

الاتاحة: http://hdl.handle.net/10044/1/70660
https://doi.org/10.1016/j.celrep.2019.06.039

المؤلفون: Hooftman, A, Peace, CG, Ryan, DG, Day, EA, Yang, M, McGettrick, AF, Yin, M, Montano, EN, Huo, L, Toller-Kawahisa, JE, Zecchini, V, Ryan, TAJ, Bolado-Carrancio, A, Casey, AM, Prag, HA, Costa, ASH, De Los Santos, G, Ishimori, M, Wallace, DJ, Venuturupalli, S, Nikitopoulou, E, Frizzell, N, Johansson, C, Von Kriegsheim, A, Murphy, MP, Jefferies, C, Frezza, C, O'Neill, LAJ

المصدر: 498 ; 490

جغرافية الموضوع: England

Relation: Nature; http://hdl.handle.net/10044/1/104575

الاتاحة: http://hdl.handle.net/10044/1/104575
https://doi.org/10.1038/s41586-023-05720-6

المؤلفون: Peruzzotti-Jametti, L, Bernstock, JD, Vicario, N, Costa, ASH, Kwok, CK, Leonardi, T, Booty, LM, Bicci, I, Balzarotti, B, Volpe, G, Mallucci, G, Manferrari, G, Donegà, M, Iraci, N, Braga, A, Hallenbeck, JM, Murphy, MP, Edenhofer, F, Frezza, C, Pluchino, S

مصطلحات موضوعية: 32 Biomedical and Clinical Sciences, 3204 Immunology, Stem Cell Research, Stem Cell Research - Nonembryonic - Human, Transplantation, Stem Cell Research - Nonembryonic - Non-Human, Regenerative Medicine, Neurosciences, 2.1 Biological and endogenous factors, 1.1 Normal biological development and functioning, Inflammatory and immune system, Neurological, Animals, Cell Line, Central Nervous System, Chronic Disease, Dinoprostone, Female, Humans, Inflammation, Macrophages, Mice, Inbred C57BL, Neural Stem Cells, Oxidative Phosphorylation, Receptors, G-Protein-Coupled, Succinic Acid

وصف الملف: application/pdf

Relation: https://www.repository.cam.ac.uk/handle/1810/273787

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/273787
https://doi.org/10.17863/CAM.20853

المؤلفون: Mills, EL, Ryan, DG, Prag, HA, Dikovskaya, D, Menon, D, Zaslona, Z, Jedrychowski, MP, Costa, ASH, Higgins, M, Hams, E, Szpyt, J, Runtsch, MC, King, MS, McGouran, JF, Fischer, R, Kessler, BM, McGettrick, AF, Hughes, MM, Carroll, RG, Booty, LM, Knatko, EV, Meakin, PJ, Ashford, MLJ, Modis, LK, Brunori, G, Sévin, DC, Fallon, PG, Caldwell, ST, Kunji, ERS, Chouchani, ET, Frezza, C, Dinkova-Kostova, AT, Hartley, RC, Murphy, MP, O'Neill, LA

Relation: https://ora.ox.ac.uk/objects/uuid:a328d53b-ce28-4ce4-aefb-839754ab5322; https://doi.org/10.1038/nature25986

الاتاحة: https://doi.org/10.1038/nature25986
https://ora.ox.ac.uk/objects/uuid:a328d53b-ce28-4ce4-aefb-839754ab5322

المؤلفون: Gonçalves, E, Sciacovelli, M, Costa, ASH, Tran, MGB, Johnson, TI, Machado, D, Frezza, C, Saez-Rodriguez, J

المصدر: Metab Eng , 45 pp. 149-157. (2018)

مصطلحات موضوعية: Cancer, Metabolism, Modelling, Phosphoproteomics

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10043363/1/1-s2.0-S1096717617303270-main.pdf; https://discovery.ucl.ac.uk/id/eprint/10043363/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10043363/1/1-s2.0-S1096717617303270-main.pdf
https://discovery.ucl.ac.uk/id/eprint/10043363/

المؤلفون: Rached, M-T, Millership, SJ, Pedroni, SMA, Choudhury, AI, Costa, ASH, Hardy, DG, Glegola, JA, Irvine, EE, Selman, C, Woodberry, MC, Yadav, VK, Khadayate, S, Vidal-Puig, A, Virtue, S, Frezza, C, Withers, D

المساهمون: Wellcome Trust, Medical Research Council

المصدر: 50 ; 38

مصطلحات موضوعية: Science & Technology, Life Sciences & Biomedicine, Endocrinology & Metabolism, Macrophage, Irs2, Obesity, Inflammation, BAT, Sympathetic neurons, ALTERNATIVELY ACTIVATED MACROPHAGES, INSULIN-RECEPTOR SUBSTRATE-2, BETA-CELL, GENE, HOMEOSTASIS, EXPRESSION, PROTEIN, SYSTEM, ROLES, CATECHOLAMINES

Relation: Molecular Metabolism; http://hdl.handle.net/10044/1/66518; https://dx.doi.org/10.1016/j.molmet.2018.11.010; 093082/Z/10/Z; 511377; MC-A654-5QB40

الاتاحة: http://hdl.handle.net/10044/1/66518
https://doi.org/10.1016/j.molmet.2018.11.010

المؤلفون: Putker, M, Crosby, P, Feeney, KA, Hoyle, NP, Costa, ASH, Gaude, E, Frezza, C, O'Neill, JS

مصطلحات موضوعية: circadian rhythm, clock gene, mammalian, pentose phosphate pathway, primary metabolism, redox signaling

وصف الملف: application/pdf

Relation: https://www.repository.cam.ac.uk/handle/1810/266324

الاتاحة: https://www.repository.cam.ac.uk/handle/1810/266324
https://doi.org/10.17863/CAM.12585

المؤلفون: Sciacovelli, M, Goncalves, E, Johnson, TI, Zecchini, VR, da Costa, ASH, Gaude, E, Drubbel, AV, Theobald, SJ, Abbo, SR, Tran, MGB, Rajeeve, V, Cardaci, S, Foster, S, Yun, H, Cutillas, P, Warren, A, Gnanapragasam, V, Gottlieb, E, Franze, K, Huntly, B, Maher, ER, Maxwell, PH, Saez-Rodriguez, J, Frezza, C

المصدر: Nature , 537 pp. 544-547. (2016)

مصطلحات موضوعية: Science & Technology, Multidisciplinary Sciences, Science & Technology - Other Topics, Renal-Cell Carcinoma, Enrichment Analysis, Deficient Cells, Cancer, Expression, Mutations, Succinate, Hydratase, Tet, Demethylases

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/1535846/1/Tran_160711%20Sciacovelli%20et%20al.pdf; https://discovery.ucl.ac.uk/id/eprint/1535846/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/1535846/1/Tran_160711%20Sciacovelli%20et%20al.pdf
https://discovery.ucl.ac.uk/id/eprint/1535846/

المؤلفون: Costa Ash., James A. Nathan, Robin Antrobus, Bailey Psj, Brian Ortmann, Christian Frezza, Jack W. Houghton

مصطلحات موضوعية: chemistry.chemical_classification, 0303 health sciences, biology, Chemistry, 030302 biochemistry & molecular biology, Mutagenesis, Metabolism, Cell biology, Lipid peroxidation, 03 medical and health sciences, Metabolic pathway, chemistry.chemical_compound, Histone, Enzyme, Lipoylation, biology.protein, Function (biology), 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e2c5d1f97a60b5fc00ce5ef1fb7ecec
https://doi.org/10.1101/2020.04.18.048082

المؤلفون: Bantug, G.R., Fischer, M., Grählert, J., Balmer, M.L., Unterstab, G., Develioglu, L., Steiner, R., Zhang, L., Costa, ASH, Gubser, P.M., Burgener, A.V., Sauder, U., Löliger, J., Belle, R., Dimeloe, S., Lötscher, J., Jauch, A., Recher, M., Hönger, G., Hall, M.N., Romero, P., Frezza, C., Hess, C.

المصدر: Immunity, vol. 48, no. 3, pp. 542-555.e6

مصطلحات موضوعية: CD8-Positive T-Lymphocytes/immunology, CD8-Positive T-Lymphocytes/metabolism, Cell Respiration, Endoplasmic Reticulum/metabolism, Endoplasmic Reticulum/ultrastructure, Energy Metabolism, Glycogen Synthase Kinase 3 beta/metabolism, Glycolysis, Immunologic Memory, Intracellular Membranes/metabolism, Lymphocyte Activation, Mechanistic Target of Rapamycin Complex 2/metabolism, Mitochondria/metabolism, Mitochondria/ultrastructure, Models, Biological, Proto-Oncogene Proteins c-akt/metabolism, Rapamycin-Insensitive Companion of mTOR Protein/deficiency, Signal Transduction, Akt, GSK3-beta, IFN-gamma, VDAC, endoplasmic reticulum, hexokinase, mTOR, memory CD8(+) T cells, mitochondria

Relation: info:eu-repo/semantics/altIdentifier/pmid/29523440; info:eu-repo/semantics/altIdentifier/eissn/1097-4180; https://serval.unil.ch/notice/serval:BIB_860F1556AA95

الاتاحة: https://serval.unil.ch/notice/serval:BIB_860F1556AA95
https://doi.org/10.1016/j.immuni.2018.02.012