المؤلفون: Pizzonero, Mathieu, Akkari, Rhalid, Bock, Xavier, Gosmini, Romain, De Lemos, Elsa, Duthion, Béranger, Newsome, Gregory, Mai, Thi-Thu-Trang, Roques, Virginie, Jary, Hélène, Lefrancois, Jean-Michel, Cherel, Laetitia, Quenehen, Vanessa, Babel, Marielle, Merayo, Nuria, Bienvenu, Natacha, Mammoliti, Oscar, Coti, Ghjuvanni, Palisse, Adeline, Cowart, Marlon, Shrestha, Anurupa, Greszler, Stephen, Van Der Plas, Steven, Jansen, Koen, Claes, Pieter, Jans, Mia, Gees, Maarten, Borgonovi, Monica, De Wilde, Gert, Conrath, Katja

المساهمون: Gal?pagos

المصدر: Journal of Medicinal Chemistry ; volume 67, issue 7, page 5216-5232 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.3c01790
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.3c01790

المؤلفون: de Poel, Eyleen, Spelier, Sacha, Korporaal, Ricardo, Lai, Ka Wai, Boj, Sylvia F., Conrath, Katja, van der Ent, Cornelis K., Beekman, Jeffrey M.

المساهمون: Longziekten onderzoek 2, Hubrecht Institute with UMC, Longziekten patientenzorg, Speerpunt Child Health, Child Health, Infection & Immunity, Onderzoek, Regenerative Medicine and Stem Cells

مصطلحات موضوعية: CFTR, CFTR modulator therapy, cystic fibrosis, F508del, forskolin induced swelling assay, intestinal organoids, personalized medicine, Biochemistry, Genetics and Molecular Biology (miscellaneous), Molecular Biology

وصف الملف: application/pdf

Relation: https://dspace.library.uu.nl/handle/1874/445352

الاتاحة: https://dspace.library.uu.nl/handle/1874/445352

المؤلفون: Van der Plas, Steven E., Kelgtermans, Hans, Mammoliti, Oscar, Menet, Christel, Tricarico, Giovanni, De Blieck, Ann, Joannesse, Caroline, De Munck, Tom, Lambin, Dominique, Cowart, Marlon, Dropsit, Sebastien, Martina, Sebastien L. X., Gees, Maarten, Wesse, Anne-Sophie, Conrath, Katja, Andrews, Martin

المصدر: Journal of Medicinal Chemistry ; volume 64, issue 18, page 13933-13933 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.1c01537
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.1c01537

المؤلفون: Labéguère, Frédéric, Dupont, Sonia, Alvey, Luke, Soulas, Florilène, Newsome, Gregory, Tirera, Amynata, Quenehen, Vanessa, Mai, Thi Thu Trang, Deprez, Pierre, Blanqué, Roland, Oste, Line, Le Tallec, Sandrine, De Vos, Steve, Hagers, Annick, Vandevelde, Ann, Nelles, Luc, Vandervoort, Nele, Conrath, Katja, Christophe, Thierry, van der Aar, Ellen, Wakselman, Emanuelle, Merciris, Didier, Cottereaux, Céline, da Costa, Cécile, Saniere, Laurent, Clement-Lacroix, Philippe, Jenkins, Laura, Milligan, Graeme, Fletcher, Stephen, Brys, Reginald, Gosmini, Romain

وصف الملف: text

Relation: https://eprints.gla.ac.uk/230270/1/230270.pdf; Labéguère, F. et al. (2020) Discovery of 9-Cyclopropylethynyl-2-((S)-1-[1,4]dioxan-2-ylmethoxy)-6,7-dihydropyrimido[6,1-a]isoquinolin-4-one (GLPG1205), a unique GPR84 negative allosteric modulator undergoing evaluation in a phase II clinical trial. Journal of Medicinal Chemistry , 63(22), pp. 13526-13545. (doi:10.1021/acs.jmedchem.0c00272 ) (PMID:32902984)

الاتاحة: https://eprints.gla.ac.uk/230270/
https://eprints.gla.ac.uk/230270/1/230270.pdf

المؤلفون: van Koningsbruggen-Rietschel, Silke, Conrath, Katja, Fischer, Rainald, Sutharsan, Sivagurunathan, Kempa, Axel, Gleiber, Wolfgang, Schwarz, Carsten, Hector, Andreas, Van Osselaer, Nancy, Pano, Arian, Corveleyn, Sam, Bwirire, Dieudonné, Santermans, Eva, Muller, Karine, Bellaire, Susan, Van de Steen, Olivier

المساهمون: Galapagos NV, AbbVie, Inc., Aspire Scientific

المصدر: Journal of Cystic Fibrosis ; volume 19, issue 2, page 292-298 ; ISSN 1569-1993

الاتاحة: http://dx.doi.org/10.1016/j.jcf.2019.09.006
https://api.elsevier.com/content/article/PII:S1569199319308902?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1569199319308902?httpAccept=text/plain

المؤلفون: Bell, Scott C., Barry, Peter J., De Boeck, Kris, Drevinek, Pavel, Elborn, J. Stuart, Plant, Barry J., Minić, Predag, Van Braeckel, Eva, Verhulst, Stijn, Muller, Karine, Kanters, Desirée, Bellaire, Susan, de Kock, Herman, Geller, David E, Conrath, Katja, Van de Steen, Olivier, van der Ent, Kors

المصدر: JOURNAL OF CYSTIC FIBROSIS ; ISSN: 1569-1993 ; ISSN: 1873-5010

مصطلحات موضوعية: Medicine and Health Sciences, Cystic fibrosis, F508del, Gating mutation, GLPG2222, Ivacaftor, CFTR modulator, CYSTIC-FIBROSIS, TEZACAFTOR-IVACAFTOR, PHASE-II, MUTATION, COMBINATION, LUMACAFTOR

وصف الملف: application/pdf

Relation: https://biblio.ugent.be/publication/8641983; http://hdl.handle.net/1854/LU-8641983; http://dx.doi.org/10.1016/j.jcf.2019.04.014; https://biblio.ugent.be/publication/8641983/file/8665291

الاتاحة: https://biblio.ugent.be/publication/8641983
http://hdl.handle.net/1854/LU-8641983
https://doi.org/10.1016/j.jcf.2019.04.014
https://biblio.ugent.be/publication/8641983/file/8665291

المؤلفون: Yeh, Han-I, Qiu, Liming, Sohma, Yoshiro, Conrath, Katja, Zou, Xiaoqin, Hwang, Tzyh-Chang

المساهمون: National Institutes of Health, Cystic Fibrosis Foundation

المصدر: Journal of General Physiology ; volume 151, issue 7, page 912-928 ; ISSN 0022-1295 1540-7748

الاتاحة: http://dx.doi.org/10.1085/jgp.201912360
https://rupress.org/jgp/article-pdf/151/7/912/1800364/jgp_201912360.pdf

المؤلفون: de Wilde, Gert, Gees, Maarten, Musch, Sara, Verdonck, Katleen, Jans, Mia, Wesse, Anne-Sophie, Singh, Ashvani K., Hwang, Tzyh-Chang, Christophe, Thierry, Pizzonero, Mathieu, Van der Plas, Steven, Desroy, Nicolas, Cowart, Marlon, Stouten, Pieter, Nelles, Luc, Conrath, Katja

المصدر: Frontiers in Pharmacology ; volume 10 ; ISSN 1663-9812

الاتاحة: http://dx.doi.org/10.3389/fphar.2019.00514
https://www.frontiersin.org/article/10.3389/fphar.2019.00514/full

المؤلفون: Davies, Jane C., Van de Steen, Olivier, van Koningsbruggen-Rietschel, Silke, Drevinek, Pavel, Derichs, Nico, McKone, Edward F., Kanters, Desirée, Allamassey, Lisa, Namour, Florence, de Kock, Herman, Conrath, Katja

المساهمون: Galapagos NV

المصدر: Journal of Cystic Fibrosis ; volume 18, issue 5, page 693-699 ; ISSN 1569-1993

الاتاحة: http://dx.doi.org/10.1016/j.jcf.2019.05.006
https://api.elsevier.com/content/article/PII:S1569199319301110?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1569199319301110?httpAccept=text/plain

المؤلفون: Gees, Maarten, Musch, Sara, Van der Plas, Steven, Wesse, Anne-Sophie, Vandevelde, Ann, Verdonck, Katleen, Mammoliti, Oscar, Hwang, Tzyh-Chang, Sonck, Kathleen, Stouten, Pieter, Swensen, Andrew M., Jans, Mia, Van der Schueren, Jan, Nelles, Luc, Andrews, Martin, Conrath, Katja

المصدر: Frontiers in Pharmacology ; volume 9 ; ISSN 1663-9812

الاتاحة: http://dx.doi.org/10.3389/fphar.2018.01221
https://www.frontiersin.org/article/10.3389/fphar.2018.01221/full

المؤلفون: Van der Plas, Steven E., Kelgtermans, Hans, De Munck, Tom, Martina, Sébastien L. X., Dropsit, Sébastien, Quinton, Evelyne, De Blieck, Ann, Joannesse, Caroline, Tomaskovic, Linda, Jans, Mia, Christophe, Thierry, van der Aar, Ellen, Borgonovi, Monica, Nelles, Luc, Gees, Maarten, Stouten, Pieter, Van Der Schueren, Jan, Mammoliti, Oscar, Conrath, Katja, Andrews, Martin

المصدر: Journal of Medicinal Chemistry ; volume 61, issue 4, page 1425-1435 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.7b01288
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.7b01288

المؤلفون: Joncour, Agnès, Desroy, Nicolas, Housseman, Christopher, Bock, Xavier, Bienvenu, Natacha, Cherel, Laëtitia, Labeguere, Virginie, Peixoto, Christophe, Annoot, Denis, Lepissier, Luce, Heiermann, Jörg, Hengeveld, Willem Jan, Pilzak, Gregor, Monjardet, Alain, Wakselman, Emanuelle, Roncoroni, Veronique, Le Tallec, Sandrine, Galien, René, David, Christelle, Vandervoort, Nele, Christophe, Thierry, Conrath, Katja, Jans, Mia, Wohlkonig, Alexandre, Soror, Sameh, Steyaert, Jan, Touitou, Robert, Fleury, Damien, Vercheval, Lionel, Mollat, Patrick, Triballeau, Nicolas, van der Aar, Ellen, Brys, Reginald, Heckmann, Bertrand

المصدر: Journal of Medicinal Chemistry ; volume 61, issue 9, page 4270-4270 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.8b00579
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b00579

المؤلفون: Yeh, Han-I, Sohma, Yoshiro, Conrath, Katja, Hwang, Tzyh-Chang

المساهمون: National Institutes of Health, Cystic Fibrosis Foundation

المصدر: Journal of General Physiology ; volume 149, issue 12, page 1105-1118 ; ISSN 0022-1295 1540-7748

الاتاحة: http://dx.doi.org/10.1085/jgp.201711886
https://rupress.org/jgp/article-pdf/149/12/1105/1796317/jgp_201711886.pdf

المؤلفون: De Genst, Erwin, Silence, Karen, Decanniere, Klaas, Conrath, Katja, Loris, Remy, Kinne, Jörg, Muyldermans, Serge, Wyns, Lode

المصدر: Proceedings of the National Academy of Sciences of the United States of America, 2006 Mar . 103(12), 4586-4591.

URL الوصول: https://www.jstor.org/stable/30048985

المؤلفون: Van der Plas, Steven E., Kelgtermans, Hans, Mammoliti, Oscar, Menet, Christel, Tricarico, Giovanni, De Blieck, Ann, Joannesse, Caroline, De Munck, Tom, Lambin, Dominique, Cowart, Marlon, Dropsit, Sebastien, Martina, Sebastien L. X., Gees, Maarten, Wesse, Anne-Sophie, Conrath, Katja, Andrews, Martin

المصدر: Journal of Medicinal Chemistry ; volume 64, issue 1, page 343-353 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.0c01796
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.0c01796

المؤلفون: van der Schaar, H.M., Leyssen, Pieter, Thibaut, H.J., de Palma, Armando, van der Linden, Lonneke, Lanke, Kjerstin H.W., Lacroix, Céline, Verbeken, Erik, Conrath, Katja, Macleod, Angus M, Mitchell, Dale R, Palmer, Nicholas J, van de Poël, Hervé, Andrews, Martin, Neyts, Johan, van Kuppeveld, F.J.M.

المساهمون: Strategic Infection Biology, Dep Infectieziekten Immunologie, I&I SIB1

مصطلحات موضوعية: 1-Phosphatidylinositol 4-Kinase, Animals, Antiviral Agents, Enterovirus, Enzyme Activation, Fluorescent Antibody Technique, HeLa Cells, Humans, Male, Mice, Molecular Structure, Pancreatitis, Virus Replication, Coronacrisis-Taverne

وصف الملف: image/pdf

Relation: https://dspace.library.uu.nl/handle/1874/287777

الاتاحة: https://dspace.library.uu.nl/handle/1874/287777

المؤلفون: van der Schaar, Hilde M., Leyssen, Pieter, Thibaut, Hendrik J., de Palma, Armando, van der Linden, Lonneke, Lanke, Kjerstin H. W., Lacroix, Céline, Verbeken, Erik, Conrath, Katja, MacLeod, Angus M., Mitchell, Dale R., Palmer, Nicholas J., van de Poël, Hervé, Andrews, Martin, Neyts, Johan, van Kuppeveld, Frank J. M.

المصدر: Antimicrobial Agents and Chemotherapy ; volume 57, issue 10, page 4971-4981 ; ISSN 0066-4804 1098-6596

الاتاحة: http://dx.doi.org/10.1128/aac.01175-13
https://journals.asm.org/doi/pdf/10.1128/AAC.01175-13

المؤلفون: Longziekten onderzoek 2, Hubrecht Institute with UMC, Longziekten patientenzorg, Speerpunt Child Health, Child Health, Infection & Immunity, Onderzoek, Regenerative Medicine and Stem Cells, de Poel, Eyleen, Spelier, Sacha, Korporaal, Ricardo, Lai, Ka Wai, Boj, Sylvia F., Conrath, Katja, van der Ent, Cornelis K., Beekman, Jeffrey M.

URL: https://doi.org/10.3389/fmolb.2021.698358
http://hdl.handle.net/1874/445352
https://dspace.library.uu.nl/handle/1874/445352
http://www.scopus.com/inward/record.url?scp=85116239726&partnerID=8YFLogxK
Frontiers in Molecular Biosciences
8
698358

المؤلفون: Govaert, Jochen, Pellis, Mireille, Deschacht, Nick, Vincke, Cécile, Conrath, Katja, Muyldermans, Serge, Saerens, Dirk

المصدر: Journal of Biological Chemistry ; volume 287, issue 3, page 1970-1979 ; ISSN 0021-9258

الاتاحة: http://dx.doi.org/10.1074/jbc.m111.242818
https://api.elsevier.com/content/article/PII:S0021925820532912?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0021925820532912?httpAccept=text/plain
https://syndication.highwire.org/content/doi/10.1074/jbc.M111.242818

المؤلفون: Stijlemans, Benoît, Caljon, Guy, Natesan, Senthil Kumar A, Saerens, Dirk, Conrath, Katja, Perez-Morga, David, Skepper, Jeremy N, Nikolaou, Alexandros, Brys, Lea, Pays, Etienne, Magez, Stefan, Field, Mark C, De Baetselier, Patrick, Muyldermans, Serge

المصدر: P L o S Pathogens, 7 (6

مصطلحات موضوعية: Sciences exactes et naturelles, Sciences bio-médicales et agricoles, Amino Acid Sequence, Animals, Antibodies, Protozoan -- immunology -- pharmacology -- therapeutic use, Antibody Affinity, Cells, Cultured, Down-Regulation -- drug effects, Endocytosis -- drug effects, Humans, Mice, Inbred C57BL, Models, Biological, Molecular, Molecular Sequence Data, Nanoparticles, Trypanocidal Agents -- pharmacology -- therapeutic use, Trypanosoma brucei brucei -- immunology -- metabolism -- physiology -- ultrastructure, Trypanosomiasis, African -- immunology -- metabolism -- therapy, Variant Surface Glycoproteins, Trypanosoma -- immunology

وصف الملف: 1 full-text file(s): application/pdf

Relation: uri/info:doi/10.1371/journal.ppat.1002072; uri/info:pii/10-PLPA-RA-4101; uri/info:pmid/21698216; uri/info:scp/79959851947; uri/info:pmcid/PMC3116811; uri/info:ulb-repo/set/1; https://dipot.ulb.ac.be/dspace/bitstream/2013/160716/4/doi_146170.pdf; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/160716

الاتاحة: http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/160716
https://dipot.ulb.ac.be/dspace/bitstream/2013/160716/4/doi_146170.pdf