المؤلفون: Jinqi Liu, Joshua Curtin, Dan You, Stephen Hillerman, Bifang Li-Wang, Rukiye Eraslan, Jenny Xie, Jesse Swanson, Ching-Ping Ho, Simone Oppenheimer, Bethanne M Warrack, Colleen A McNaney, David M Nelson, Jordan Blum, Taeg Kim, Mark Fereshteh, Michael Reily, Petia Shipkova, Anwar Murtaza, Miguel Sanjuan, John T Hunt, Luisa Salter-Cid

المصدر: PLoS ONE, Vol 14, Iss 3, p e0212670 (2019)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/7604dc75ad594b68a709196c2f123df0

المؤلفون: Dieter M. Drexler, Colleen A. McNaney, Yingzi Wang, Xiaohua Huang, Michael D. Reily

المصدر: Journal of Applied Bioanalysis, Vol 4, Iss 1, Pp 26-31 (2018)

مصطلحات موضوعية: LC-MS bioanalysis, quantitative NMR, data accuracy, data precision, quality control of stock solutions of analyte reference standards, quality control of stock solutions of assay reagents, Pharmacy and materia medica, RS1-441, Chemistry, QD1-999

Relation: https://doi.org/10.17145/jab.18.005; https://doaj.org/toc/2405-710X; https://doaj.org/article/111ce73735e347219517bd5d6dae8b38

الاتاحة: https://doi.org/10.17145/jab.18.005
https://doaj.org/article/111ce73735e347219517bd5d6dae8b38

المؤلفون: Petia Shipkova, Giridhar S. Tirucherai, Arun J. Sanyal, Diane E. Shevell, Benjamin E. Decato, Colleen A. McNaney, Yi Luo, Edgar D. Charles, Abraham Apfel

المصدر: JHEP Reports

مصطلحات موضوعية: GCDCA, glyco-chenodeoxycholic acid, C4, 7α-hydroxy-4-cholesten-3-one, Deoxycholic acid, FGF21, fibroblast growth factor 21, AST, aspartate aminotransferase, PGBF, pegbelfermin, Gastroenterology, chemistry.chemical_compound, FGF21, QD, once daily, Chenodeoxycholic acid, Nonalcoholic fatty liver disease, Immunology and Allergy, LCA, lithocholic acid, CA, cholic acid, Bile acid, LC, liquid chromatography, Fatty liver, baiH, 7β-hydroxy-3-oxo-delta4-cholenoic acid oxidoreductase, BA, bile acid, Research Article, TCDCA, tauro-chenodeoxycholic acid, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, medicine.drug_class, NASH, non-alcoholic steatohepatitis, TDCA, tauro-deoxycholic acid, hdhA, 7-alpha-hydroxysteroid dehydrogenase, GUDCA, glyco-ursodeoxycholic acid, Bile salt hydrolase, CYP7A1, cytochrome P450 7A1, PEGylated, polyethylene glycol-conjugated, UDCA, ursodeoxycholic acid, CDCA, chenodeoxycholic acid, FXR, farnesoid X receptor, TCA, tauro-cholic acid, Internal medicine, 7α-Hydroxy-4-cholesten-3-one, ALT, alanine aminotransferase, Internal Medicine, medicine, GCA, glyco-cholic acid, C4, Hepatology, business.industry, T2DM, type 2 diabetes mellitus, medicine.disease, GDCA, glyco-deoxycholic acid, QW, once weekly, chemistry, DCA, deoxycholic acid, MS, mass spectrometry, BSH, bile salt hydrolase, baiCD, 7α-hydroxy-3-oxo-delta4-cholenoic acid oxidoreductase, PRO-C3, N-terminal type III collagen propeptide, HbA1c, glycated haemoglobin, Microbiome, HFF, hepatic fat fraction, Steatosis, Steatohepatitis, business, ApoA1, apolipoprotein A1, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c523b47362c4cc87193b195c73edfb6d
https://pubmed.ncbi.nlm.nih.gov/34977519

المؤلفون: Xiaohua Huang, Michael D. Reily, Dieter M. Drexler, Colleen A. McNaney, Yingzi Wang

المصدر: Journal of Applied Bioanalysis, Vol 4, Iss 1, Pp 26-31 (2018)

مصطلحات موضوعية: Accuracy and precision, Bioanalysis, Materials science, Chromatography, quality control of stock solutions of assay reagents, lcsh:RS1-441, lcsh:Pharmacy and materia medica, lcsh:Chemistry, quality control of stock solutions of analyte reference standards, lcsh:QD1-999, Liquid chromatography–mass spectrometry, data accuracy, data precision, quantitative NMR, LC-MS bioanalysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eef1db041feb2b034cef232706ebaaa
https://doaj.org/article/111ce73735e347219517bd5d6dae8b38

المؤلفون: Yurong Lai, Regina V. Oliveira, W. Griffith Humphreys, Yueping Zhang, David M. Nelson, Jinping Gan, Petia Shipkova, Michael D. Reily, Xiaomei Gu, Ching Su, Hong Shen, Weiqi Chen, Colleen A. McNaney, Punit Marathe

المصدر: Drug Metabolism and Disposition. 46:178-188

مصطلحات موضوعية: 0301 basic medicine, Pyridoxic Acid, Organic anion transporter 1, Pharmaceutical Science, Endogeny, Organic Anion Transporters, Sodium-Independent, Pharmacology, 030226 pharmacology & pharmacy, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, Organic Anion Transport Protein 1, 0302 clinical medicine, Metabolomics, medicine, Animals, Humans, biology, Probenecid, Homovanillic acid, Furosemide, Biological Transport, Homovanillic Acid, Transporter, Macaca fascicularis, HEK293 Cells, 030104 developmental biology, Biochemistry, chemistry, biology.protein, Biomarkers, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dddd7f42e11c693cf5ccc8e15104b64a
https://doi.org/10.1124/dmd.117.077586

المؤلفون: Dieter M. Drexler, Ommega Internationals, Colleen A. McNaney

المصدر: Journal of Analytical, Bioanalytical and Separation Techniques. 1:3-7

مصطلحات موضوعية: chemistry.chemical_compound, Metabolomics, Chromatography, chemistry, Scientific method, Gas chromatography–mass spectrometry, Derivatization

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f1ffeaa3413055e8dd33b8656a0abc6f
https://doi.org/10.15436/2476-1869.16.1047

المؤلفون: Joshua C. Curtin, Stephen Hillerman, Rukiye Eraslan, Jinqi Liu, Dan You, Bifang Li-Wang, Taeg Kim, Anwar Murtaza, John T. Hunt, David M. Nelson, Jesse Swanson, Jordan Blum, Mark Fereshteh, Michael D. Reily, Petia Shipkova, Jenny Xie, Bethanne M. Warrack, Luisa Salter-Cid, Colleen A. McNaney, Simone Oppenheimer, Miguel Sanjuan, Ching-Ping Ho

المصدر: PLoS ONE, Vol 14, Iss 3, p e0212670 (2019)
PLoS ONE

مصطلحات موضوعية: 0301 basic medicine, Adenosine, Physiology, medicine.medical_treatment, Glycobiology, Pathology and Laboratory Medicine, Biochemistry, Mice, White Blood Cells, 0302 clinical medicine, Animal Cells, Immune Physiology, Tumor Microenvironment, Medicine and Health Sciences, Cytotoxic T cell, Lymphocytes, Immunologic Surveillance, Immune Response, Immunity, Cellular, Innate Immune System, Multidisciplinary, Kinase, T Cells, Nucleosides, Regulatory T cells, Glycosylamines, 030220 oncology & carcinogenesis, Cytokines, Medicine, Cellular Types, Research Article, Immune Cells, Science, Immunology, Cytotoxic T cells, Biology, Protein Serine-Threonine Kinases, Immune Suppression, 03 medical and health sciences, Immune system, Signs and Symptoms, Diagnostic Medicine, Cell Line, Tumor, medicine, Animals, Point Mutation, Kinase activity, Tumor microenvironment, Blood Cells, Biology and Life Sciences, Immunotherapy, Neoplasms, Experimental, Cell Biology, Molecular Development, Mice, Mutant Strains, 030104 developmental biology, Protein kinase domain, Immune System, Cancer research, CD8, Developmental Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ccd2972f9b8159008a872a7d2c5b24b
https://doaj.org/article/7604dc75ad594b68a709196c2f123df0

المؤلفون: Joseph L. Cantone, Timothy V Olah, Colleen A. McNaney, Yulia Benitex, Dieter M. Drexler, Omar S. Barnaby

المصدر: Bioanalysis. 7:2501-2513

مصطلحات موضوعية: Analyte, Bioanalysis, Chromatography, Complex matrix, Clinical Biochemistry, Disease progression, Electrophoresis, Capillary, Endogeny, General Medicine, Analytical Chemistry, Medical Laboratory Technology, chemistry.chemical_compound, Pharmaceutical Preparations, chemistry, Tandem Mass Spectrometry, Isotope Labeling, Animals, Humans, General Pharmacology, Toxicology and Pharmaceutics, Derivatization, Biomarkers, Chromatography, High Pressure Liquid, Volume concentration

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca1d7dc1cfea47f1c6635bd957a5857f
https://doi.org/10.4155/bio.15.171

المؤلفون: Brian R. Holder, Dieter M. Drexler, Colleen A. McNaney, David Luchetti, Eric Schaeffer

المصدر: Biomedical Chromatography. 29:1375-1379

مصطلحات موضوعية: Pharmacology, Bioanalysis, Chromatography, Chemistry, Hydrophilic interaction chromatography, Clinical Biochemistry, General Medicine, Mass spectrometry, Biochemistry, Analytical Chemistry, chemistry.chemical_compound, Cerebrospinal fluid, Liquid chromatography–mass spectrometry, Potential biomarkers, Drug Discovery, medicine, Derivatization, Acetylcarnitine, Molecular Biology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::983522d87f945341cb18ab80db743422
https://doi.org/10.1002/bmc.3433

المؤلفون: John E. Leet, Colleen A. McNaney, Jeremy Stewart, Dieter M. Drexler, John J. Herbst

المصدر: SLAS Discovery. 19:1409-1414

مصطلحات موضوعية: Monoamine Oxidase Inhibitors, Chromatography, Monoamine oxidase B inhibitors, Chemistry, Monoamine oxidase, Drug Evaluation, Preclinical, Pipette, Lauric Acids, Signal-To-Noise Ratio, Sulfides, Biochemistry, Gas Chromatography-Mass Spectrometry, Analytical Chemistry, Cost savings, Dodecanol, Molecular Medicine, Biologically active substances, 3-Mercaptopropionic Acid, Monoamine Oxidase, Plastics, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3c2e5f1af768f632b7a5d2e9aefbc36
https://doi.org/10.1177/1087057114551523

المؤلفون: Daniel G. Morgan, Colleen A. McNaney, Fu-ni Luan, Yulia Benitex, Eric Shields, Timothy V Olah, Dieter M. Drexler

المصدر: Bioanalysis. 6:1901-1905

مصطلحات موضوعية: Bioanalysis, Clinical Biochemistry, Receptors, Metabotropic Glutamate, Mass spectrometry, Benzoates, Analytical Chemistry, chemistry.chemical_compound, Limit of Detection, Tandem Mass Spectrometry, Liquid chromatography–mass spectrometry, Animals, Amino Acids, General Pharmacology, Toxicology and Pharmaceutics, Derivatization, chemistry.chemical_classification, Chromatography, Reverse-Phase, Chromatography, Chemistry, General Medicine, Bridged Bicyclo Compounds, Heterocyclic, Rats, Hexane, Medical Laboratory Technology, Dicarboxylic acid, Reagent, Hydrophobic and Hydrophilic Interactions, Derivative (chemistry), Chromatography, Liquid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e30a133487c5139e10c778be6d02bb7
https://doi.org/10.4155/bio.14.103

المؤلفون: Colleen A. McNaney, Dieter M. Drexler, David Luchetti, Timothy V Olah, Daniel G. Morgan, Yulia Benitex, Eric Schaeffer

المصدر: Rapid Communications in Mass Spectrometry. 27:1882-1886

مصطلحات موضوعية: Microdialysis, Chromatography, Organic Chemistry, Central nervous system, Glutamate receptor, Isolated brain, Pharmacology, Analytical Chemistry, chemistry.chemical_compound, medicine.anatomical_structure, Cerebrospinal fluid, Monoamine neurotransmitter, chemistry, Dopamine, medicine, Neurotransmitter, Spectroscopy, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5f03b198e273093a2eaad997e6f6470e
https://doi.org/10.1002/rcm.6639

المؤلفون: James V. Belcastro, Colleen A. McNaney, Robert Langish, Dieter M. Drexler, Adrienne A. Tymiak, Kenneth S. Santone, Serhiy Hnatyshyn, Kurt J. Edinger, Petia Shipkova, Mark Sanders, Tatyana Zvyaga, Kenneth E.J. Dickinson, Jonathan L. Josephs

المصدر: ASSAY and Drug Development Technologies. 5:247-264

مصطلحات موضوعية: Quality Control, Drug, media_common.quotation_subject, Drug Evaluation, Preclinical, Mass spectrometry, Mass Spectrometry, Liquid chromatography–mass spectrometry, Drug Discovery, Liver microsomes, NADPH-Ferrihemoprotein Reductase, media_common, Chromatography, Chemistry, Reproducibility of Results, Structural integrity, Robotics, Metabolic stability, Pharmaceutical Preparations, Data Interpretation, Statistical, Solvents, Molecular Medicine, Indicators and Reagents, Spectrophotometry, Ultraviolet, Uv detection, Software, Chromatography, Liquid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7689bed173b88b9f308efae344982c5
https://doi.org/10.1089/adt.2006.038

المؤلفون: Brian R, Holder, Colleen A, McNaney, David, Luchetti, Eric, Schaeffer, Dieter M, Drexler

المصدر: Biomedical chromatography : BMC. 29(9)

مصطلحات موضوعية: Macaca fascicularis, Mice, Dogs, Tandem Mass Spectrometry, Animals, Humans, Acetylcarnitine, Hydrophobic and Hydrophilic Interactions, Rats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::bed2745ebdf0f85eddb74c37587b2fe0
https://pubmed.ncbi.nlm.nih.gov/25712252

المؤلفون: Dieter M. Drexler, Jeffrey M. Labasi, Daniel G. Morgan, Timothy V Olah, Yulia Benitex, Colleen A. McNaney, David Luchetti

المصدر: Analytical biochemistry. 452

مصطلحات موضوعية: Agonist, animal structures, Chromatography, medicine.drug_class, Biophysics, Succinimides, Cell Biology, Phosphate, Mass spectrometry, Biochemistry, Mass Spectrometry, chemistry.chemical_compound, Phosphoserine, Cerebrospinal fluid, Organophosphorus Compounds, chemistry, Liquid chromatography–mass spectrometry, Bromide, Metabotropic glutamate receptor, medicine, Derivatization, Molecular Biology, Chromatography, Liquid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a5b3ab2dea72813816001c3fa67b47
https://pubmed.ncbi.nlm.nih.gov/24534252

المؤلفون: Yulia, Benitex, Colleen A, McNaney, David, Luchetti, Eric, Schaeffer, Timothy V, Olah, Daniel G, Morgan, Dieter M, Drexler

المصدر: Rapid communications in mass spectrometry : RCM. 27(16)

مصطلحات موضوعية: Histamine Agents, Tandem Mass Spectrometry, Methylhistamines, Animals, Biomarkers, Chromatography, High Pressure Liquid, Histamine, Rats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::c9e3bf0e161b9d3e7d2744357a752ef7
https://pubmed.ncbi.nlm.nih.gov/23857934

المؤلفون: Paul H. Siedlik, David B. Haughey, Patricia M. Klockowski, Linda Balogh, Richard R. Brown, Mary S. Collis, Colleen A. McNaney

المصدر: Journal of Pharmaceutical Sciences. 83:1582-1585

مصطلحات موضوعية: Quality Control, Detection limit, Accuracy and precision, Chromatography, Calibration curve, Chemistry, Pharmaceutical Science, Reversed-phase chromatography, High-performance liquid chromatography, Fluorescence spectroscopy, Spectrometry, Fluorescence, Tacrine, medicine, Humans, Cholinesterase Inhibitors, Quantitative analysis (chemistry), Chromatography, High Pressure Liquid, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a1b8ce621f7ec556e5081dde98a0a31
https://doi.org/10.1002/jps.2600831113

المؤلفون: Stefan Ruepp, Michael D. Reily, Colleen A. McNaney, Nelly Aranibar, Petia Shipkova, Oliver Fiehn, Donald G. Robertson, Serhiy Hnatyshyn, Steven A. Stryker

المصدر: Chemical research in toxicology. 24(4)

مصطلحات موضوعية: Male, medicine.medical_specialty, Time Factors, Biology, Carbohydrate metabolism, Toxicology, Rats, Sprague-Dawley, chemistry.chemical_compound, Metabolomics, Internal medicine, medicine, Metabolome, Animals, Glycolysis, chemistry.chemical_classification, Clinical pathology, Cholesterol, Gene Expression Profiling, Fatty acid, General Medicine, Fasting, Rats, Metabolic pathway, Endocrinology, Glucose, chemistry, Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81cbef20cb8186132c6574daee3fd08
https://pubmed.ncbi.nlm.nih.gov/21381695

المؤلفون: Serhiy Hnatyshyn, Dieter M. Drexler, Jay O. Knipe, Colleen A. McNaney, James V. Belcastro, Mark Sanders, Tatyana Zvyaga

المصدر: Assay and drug development technologies. 6(1)

مصطلحات موضوعية: Drug, media_common.quotation_subject, Drug Evaluation, Preclinical, Mass spectrometry, Mass Spectrometry, Automation, Mice, Pharmacokinetics, Liquid chromatography–mass spectrometry, Spectrophotometry, Drug Discovery, medicine, Animals, Chromatography, High Pressure Liquid, media_common, Electronic Data Processing, Chromatography, medicine.diagnostic_test, Chemistry, Half-life, Metabolic stability, Rats, Pharmaceutical Preparations, Data Interpretation, Statistical, Microsomes, Liver, Solvents, Molecular Medicine, Indicators and Reagents, Spectrophotometry, Ultraviolet, Ion trap, Software, Half-Life

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5e9919e121b0dd1be66f31dfe89e85f
https://pubmed.ncbi.nlm.nih.gov/18336089

المؤلفون: Colleen A. McNaney, Dieter M. Drexler, Serhiy Y. Hnatyshyn, Tatyana A. Zvyaga, Jay O. Knipe, James V. Belcastro, Mark Sanders

المصدر: Assay & Drug Development Technologies; Feb2008, Vol. 6 Issue 1, p121-129, 9p

مصطلحات موضوعية: DRUG development, LIQUID chromatography, ENZYMES, MICROSOMES, METABOLISM