المؤلفون: Mohammad, H., Marchisella, F., Ortega-Martinez, S., Hollos, P., Eerola, K., Komulainen, E., Kulesskaya, N., Freemantle, E., Fagerholm, V., Savontous, E., Rauvala, H., Peterson, B. D., van Praag, H., Coffey, E. T.

المساهمون: Neuroscience Center, University of Helsinki

مصطلحات موضوعية: N-TERMINAL KINASE, CEREBELLAR GRANULE NEURONS, C-JUN, DENTATE GYRUS, DORSOVENTRAL AXIS, GLUCOCORTICOID-RECEPTOR, MOLECULAR-MECHANISMS, VENTRAL HIPPOCAMPUS, CEREBRAL-ISCHEMIA, MAJOR DEPRESSION, Neurosciences, Neurology and psychiatry

وصف الملف: application/pdf

Relation: We are grateful to Petteri Piepponen, Jaakko Kopra and Juho-Matti Renko at the University of Helsinki for training HM to carry out cannulation and mini-pump implant surgeries. We thank the Cell Imaging Core at Turku Centre for Biotechnology for providing devices and technical support. This work was funded by EU FP7 ITN 608346 r'BIRTH and Academy of Finland Grants 135090 and 255537 to ETC that supported HM, FM, E F and SO-M, and the Sigrid Juselius Foundation Grant to ETC that funded PH. In addition, we thank the Doctoral Network in Molecular Biosciences at Abo Akademi University for funding HM and PH and the Finnish Graduate School of Neuroscience for funding EK. This research was funded in part by the National Institute on Aging, Intramural Research Program (to BDP and HvP).; Mohammad , H , Marchisella , F , Ortega-Martinez , S , Hollos , P , Eerola , K , Komulainen , E , Kulesskaya , N , Freemantle , E , Fagerholm , V , Savontous , E , Rauvala , H , Peterson , B D , van Praag , H & Coffey , E T 2018 , ' JNK1 controls adult hippocampal neurogenesis and imposes cell-autonomous control of anxiety behaviour from the neurogenic niche ' , Molecular Psychiatry , vol. 23 , no. 2 , pp. 362-374 . https://doi.org/10.1038/mp.2016.203; ORCID: /0000-0001-5517-8525/work/53517871; http://hdl.handle.net/10138/233496; fb71212b-b8d5-4284-acd2-6bc7fb9725d7; 84995459575; 000423441700022

الاتاحة: http://hdl.handle.net/10138/233496

المؤلفون: Mohammad, H, Marchisella, F, Ortega-Martinez, S, Hollos, P, Eerola, K, Komulainen, E, Kulesskaya, N, Freemantle, E, Fagerholm, V, Savontous, E, Rauvala, H, Peterson, B D, van Praag, H, Coffey, E T

المصدر: Molecular Psychiatry ; volume 23, issue 2, page 487-487 ; ISSN 1359-4184 1476-5578

الاتاحة: https://doi.org/10.1038/mp.2017.21
http://www.nature.com/articles/mp201721.pdf
http://www.nature.com/articles/mp201721
http://www.nature.com/doifinder/10.1038/mp.2017.21

المؤلفون: Mohammad, H, Marchisella, F, Ortega-Martinez, S, Hollos, P, Eerola, K, Komulainen, E, Kulesskaya, N, Freemantle, E, Fagerholm, V, Savontous, E, Rauvala, H, Peterson, B D, van Praag, H, Coffey, E T

المصدر: Molecular Psychiatry ; volume 23, issue 2, page 362-374 ; ISSN 1359-4184 1476-5578

الاتاحة: http://dx.doi.org/10.1038/mp.2016.203
http://www.nature.com/articles/mp2016203.pdf
http://www.nature.com/articles/mp2016203
http://www.nature.com/doifinder/10.1038/mp.2016.203

المؤلفون: Björkblom, Benny, Padzik, A., Mohammad, H., Westerlund, N., Komulainen, E., Hollos, P., Parviainen, L., Papageorgiou, A. C., Iljin, K., Kallioniemi, O., Kallajoki, M., Courtney, M. J., Mågård, M., James, P., Coffey, E. T.

المصدر: Molecular and Cellular Biology. 32(17):3513-3526

مصطلحات موضوعية: Cell Biology, Molecular Biology

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-188651

المؤلفون: Westerlund, N., Zdrojewska, J., Padzik, A., Komulainen, E., Bjorkblom, B., Rannikko, E., Tararuk, T., Garcia-Frigola, C., Sandholm, J., Nguyen, Laurent, Kallunki, T., Courtney, M. J., Coffey, E. T.

المصدر: Nature Neuroscience (2011)

مصطلحات موضوعية: Cortex, microtubules, migration, Human health sciences, Neurology, Sciences de la santé humaine, Neurologie

Relation: urn:issn:1097-6256; urn:issn:1546-1726; https://orbi.uliege.be/handle/2268/125779; info:hdl:2268/125779; info:pmid:21297631

الاتاحة: https://orbi.uliege.be/handle/2268/125779
https://doi.org/10.1038/nn.2755

المؤلفون: Cao, J., Semenova, M. M., Solovyan, V. T., Han, J. H., Coffey, E. T., Courtney, M. J., 韩家淮

مصطلحات موضوعية: CEREBELLAR GRANULE NEURONS, DNA LOOP DOMAINS, CELL-DEATH, SYMPATHETIC NEURONS, CASPASE ACTIVATION, MOUSE HIPPOCAMPUS, CEREBRAL-ISCHEMIA, P38, JNK, INHIBITION

Relation: Journal of Biological Chemistry,279(34):35903-35913; ISI:000223303400091; http://dspace.xmu.edu.cn/handle/2288/65841

الاتاحة: http://dspace.xmu.edu.cn/handle/2288/65841

المؤلفون: Hietakangas, V, Elo, I, Rosenström, H, Coffey, E T, Kyriakis, J M, Eriksson, J E, Sistonen, L

المصدر: Hietakangas , V , Elo , I , Rosenström , H , Coffey , E T , Kyriakis , J M , Eriksson , J E & Sistonen , L 2001 , ' Activation of the MKK4-JNK pathway during erythroid differentiation of K562 cells is inhibited by the heat shock factor 2-beta isoform ' , FEBS Letters , vol. 505 , no. 1 , pp. 168–172 . https://doi.org/10.1016/S0014-5793(01)02810-1 , https://doi.org/10.1016/s0014-5793(01)02810-1

مصطلحات موضوعية: Anisomycin/pharmacology, Cell Differentiation, Enzyme Activation/drug effects, Enzyme Inhibitors/pharmacology, Erythroid Precursor Cells/metabolism, Heat-Shock Proteins/genetics, Hemin/pharmacology, Humans, JNK Mitogen-Activated Protein Kinases, K562 Cells, MAP Kinase Kinase 4, MAP Kinase Kinase 7, Mitogen-Activated Protein Kinase Kinases/metabolism, Mitogen-Activated Protein Kinases/antagonists & inhibitors, Protein Isoforms, Proto-Oncogene Proteins c-jun/genetics, Staurosporine/pharmacology, Transcription Factors/genetics

الاتاحة: https://research.abo.fi/en/publications/e73f6b3f-3fe5-4779-9699-2a9d08588639
https://doi.org/10.1016/S0014-5793(01)02810-1

المؤلفون: Coffey, E T, Hongisto, V, Dickens, M, Davis, R J, Courtney, M J

المصدر: Coffey , E T , Hongisto , V , Dickens , M , Davis , R J & Courtney , M J 2000 , ' Dual roles for c-Jun N-terminal kinase in developmental and stress responses in cerebellar granule neurons ' , Journal of Neuroscience , vol. 20 , no. 20 , pp. 7602-13 .

مصطلحات موضوعية: Animals, Anisomycin/pharmacology, Cell Differentiation/physiology, Cell Nucleus/metabolism, Cells, Cultured, Cerebellum/cytology, Culture Media, Serum-Free/pharmacology, Cytoplasm/metabolism, Excitatory Amino Acid Antagonists/pharmacology, Gene Expression Regulation, Developmental/drug effects, Humans, Isoenzymes/biosynthesis, JNK Mitogen-Activated Protein Kinases, MAP Kinase Kinase 4, MAP Kinase Kinase 7, Mitogen-Activated Protein Kinase Kinases/metabolism, Mitogen-Activated Protein Kinases/genetics, Neurons/cytology, Prosencephalon/cytology, Protein Synthesis Inhibitors/pharmacology, Protein Transport/physiology, RNA, Messenger/metabolism, Rats, Sprague-Dawley, Signal Transduction/physiology, Stress

Relation: https://research.abo.fi/en/publications/4bd04a35-608c-4b75-80f7-641a1565e087

الاتاحة: https://research.abo.fi/en/publications/4bd04a35-608c-4b75-80f7-641a1565e087

المؤلفون: Courtney, M J, Coffey, E T

المصدر: Courtney , M J & Coffey , E T 1999 , ' The mechanism of Ara-C-induced apoptosis of differentiating cerebellar granule neurons ' , European Journal of Neuroscience , vol. 11 , no. 3 , pp. 1073-84 . https://doi.org/10.1046/j.1460-9568.1999.00520.x

مصطلحات موضوعية: Androstadienes/pharmacology, Animals, Antimetabolites, Antineoplastic/pharmacology, Apoptosis/drug effects, Benzamides, CDC2 Protein Kinase/analysis, CDC2-CDC28 Kinases, Cell Differentiation/physiology, Cell Survival/physiology, Cerebellum/cytology, Cyclin-Dependent Kinase 2, Cyclin-Dependent Kinase 4, Cyclin-Dependent Kinase 5, Cyclin-Dependent Kinases/analysis, Cytarabine/pharmacology, Enzyme Inhibitors/pharmacology, Flavonoids/pharmacology, Imatinib Mesylate, Imidazoles/pharmacology, Mitogen-Activated Protein Kinase 12, Mitogen-Activated Protein Kinases, Neurons/chemistry, Piperazines/pharmacology, Piperidines/pharmacology, Poly (ADP-Ribose) Polymerase-1, Poly(ADP-ribose) Polymerases, Protein Kinases/metabolism, Protein Serine-Threonine Kinases/analysis, Proteins/metabolism

Relation: https://research.abo.fi/en/publications/8b7926f4-6f96-4f52-bbb6-c96506a56634

الاتاحة: https://research.abo.fi/en/publications/8b7926f4-6f96-4f52-bbb6-c96506a56634
https://doi.org/10.1046/j.1460-9568.1999.00520.x

المؤلفون: Holmström, T H, Chow, S C, Elo, I, Coffey, E T, Orrenius, S, Sistonen, L, Eriksson, J E

المصدر: Holmström , T H , Chow , S C , Elo , I , Coffey , E T , Orrenius , S , Sistonen , L & Eriksson , J E 1998 , ' Suppression of Fas/APO-1-mediated apoptosis by mitogen-activated kinase signaling ' , Journal of Immunology , vol. 160 , no. 6 , pp. 2626–2636 .

مصطلحات موضوعية: Apoptosis, Calcium-Calmodulin-Dependent Protein Kinases/physiology, Enzyme Activation, Flavonoids/pharmacology, Humans, Jurkat Cells, Lymphocyte Activation, T-Lymphocytes/immunology, Tumor Cells, Cultured, fas Receptor/physiology

الاتاحة: https://research.abo.fi/en/publications/ff51465f-1de7-493c-888a-e7fb917d4384

المؤلفون: Coffey, E T, Akerman, K E, Courtney, M J

المصدر: Coffey , E T , Akerman , K E & Courtney , M J 1997 , ' Brain derived neurotrophic factor induces a rapid upregulation of synaptophysin and tau proteins via the neurotrophin receptor TrkB in rat cerebellar granule cells ' , Neuroscience Letters , vol. 227 , no. 3 , pp. 177-80 . https://doi.org/10.1016/s0304-3940(97)00335-2

مصطلحات موضوعية: Animals, Antibodies, Monoclonal, Brain-Derived Neurotrophic Factor/pharmacology, Cerebellum/chemistry, Immunoblotting, Proto-Oncogene Proteins c-fos/chemistry, Rats, Receptor, Ciliary Neurotrophic Factor, Receptors, Nerve Growth Factor/analysis, Signal Transduction/physiology, Synaptophysin/analysis, tau Proteins/analysis, socio, stat

Relation: https://research.abo.fi/en/publications/c392f833-5fca-4f6b-8cd7-bade708cfbab

الاتاحة: https://research.abo.fi/en/publications/c392f833-5fca-4f6b-8cd7-bade708cfbab

المؤلفون: Coffey, E T, Courtney, M J

المصدر: Coffey , E T & Courtney , M J 1997 , ' Regulation of SAPKs in CNS neurons ' , Biochemical Society Transactions , vol. 25 , no. 4 , pp. S568 . https://doi.org/10.1042/bst025s568

مصطلحات موضوعية: Animals, Cells, Cultured, Cerebellum/enzymology, Gene Expression Regulation, Enzymologic, Kinetics, Neurons/enzymology, Protein Kinases/biosynthesis, Recombinant Fusion Proteins/biosynthesis, Signal Transduction, Stress, Physiological, Time Factors, Transfection

Relation: https://research.abo.fi/en/publications/5f271c6f-b5ce-439b-98c7-7118f6b752ce

الاتاحة: https://research.abo.fi/en/publications/5f271c6f-b5ce-439b-98c7-7118f6b752ce
https://doi.org/10.1042/bst025s568

المؤلفون: Määttä, J A, Coffey, E T, Hermonen, J A, Salmi, A A, Hinkkanen, A E

المصدر: Määttä , J A , Coffey , E T , Hermonen , J A , Salmi , A A & Hinkkanen , A E 1997 , ' Detection of myelin basic protein isoforms by organic concentration ' , Biochemical and Biophysical Research Communications , vol. 238 , no. 2 , pp. 498-502 . https://doi.org/10.1006/bbrc.1997.7318

مصطلحات موضوعية: Animals, Antibodies, Brain Chemistry, Cattle, Chickens, Fishes, Guinea Pigs, Humans, Methods, Mice, Myelin Basic Protein/chemistry, Rabbits, Rats, Species Specificity, Swine

Relation: https://research.abo.fi/en/publications/f5397892-c50c-40a0-ae71-8ce46cacdc50

الاتاحة: https://research.abo.fi/en/publications/f5397892-c50c-40a0-ae71-8ce46cacdc50
https://doi.org/10.1006/bbrc.1997.7318

المؤلفون: Courtney, M J, Akerman, K E, Coffey, E T

المصدر: Courtney , M J , Akerman , K E & Coffey , E T 1997 , ' Neurotrophins protect cultured cerebellar granule neurons against the early phase of cell death by a two-component mechanism ' , The Journal of neuroscience : the official journal of the Society for Neuroscience , vol. 17 , no. 11 , pp. 4201-11 .

مصطلحات موضوعية: Androstadienes/pharmacology, Animals, Brain-Derived Neurotrophic Factor/pharmacology, Carcinogens/pharmacology, Cell Death/drug effects, Cell Survival/drug effects, Cells, Cultured/chemistry, Cerebellum/cytology, Enzyme Inhibitors/pharmacology, Gene Expression Regulation/physiology, Genes, Immediate-Early/genetics, NF-kappa B/analysis, Nerve Growth Factors/pharmacology, Neurons/chemistry, Neuroprotective Agents/pharmacology, Neurotrophin 3, Protein Kinase C/metabolism, Proto-Oncogene Proteins/analysis, Rats, Receptor Protein-Tyrosine Kinases/analysis, Receptor, Ciliary Neurotrophic Factor, Nerve Growth Factor, trkA, Receptors, Nerve Growth Factor/analysis, Tetradecanoylphorbol Acetate/pharmacology, Tumor Necrosis Factor-alpha/pharmacology

Relation: https://research.abo.fi/en/publications/24c746a3-97d2-4cfb-99b2-dfe849ee8d12

الاتاحة: https://research.abo.fi/en/publications/24c746a3-97d2-4cfb-99b2-dfe849ee8d12

المؤلفون: Coffey, E T, Herrero, I, Sihra, T S, Sánchez-Prieto, J, Nicholls, D G

المصدر: Coffey , E T , Herrero , I , Sihra , T S , Sánchez-Prieto , J & Nicholls , D G 1994 , ' Glutamate exocytosis and MARCKS phosphorylation are enhanced by a metabotropic glutamate receptor coupled to a protein kinase C synergistically activated by diacylglycerol and arachidonic acid ' , Journal of Neurochemistry , vol. 63 , no. 4 , pp. 1303-10 . https://doi.org/10.1046/j.1471-4159.1994.63041303.x

مصطلحات موضوعية: Animals, Arachidonic Acid/pharmacology, Calcium/metabolism, Cerebral Cortex/metabolism, Cycloleucine/analogs & derivatives, Cytosol/metabolism, Diglycerides/metabolism, Drug Synergism, Enzyme Activation, Exocytosis, Glutamic Acid/metabolism, Intracellular Signaling Peptides and Proteins, Male, Membrane Proteins, Myristoylated Alanine-Rich C Kinase Substrate, Neurotoxins/pharmacology, Phosphorylation, Protein Kinase C/metabolism, Proteins/metabolism, Rats, Wistar, Receptors, Metabotropic Glutamate/agonists, Synaptosomes/metabolism

Relation: https://research.abo.fi/en/publications/d6caccc2-9392-46e1-8495-70d32ba6b821

الاتاحة: https://research.abo.fi/en/publications/d6caccc2-9392-46e1-8495-70d32ba6b821
https://doi.org/10.1046/j.1471-4159.1994.63041303.x

المؤلفون: Coffey, E T, Sihra, T S, Nicholls, D G, Pocock, J M

المصدر: Coffey , E T , Sihra , T S , Nicholls , D G & Pocock , J M 1994 , ' Phosphorylation of synapsin I and MARCKS in nerve terminals is mediated by Ca2+ entry via an Aga-GI sensitive Ca2+ channel which is coupled to glutamate exocytosis ' , FEBS Letters , vol. 353 , no. 3 , pp. 264-8 . https://doi.org/10.1016/0014-5793(94)01061-7

مصطلحات موضوعية: Animals, Calcium/metabolism, Calcium Channels/drug effects, Cerebral Cortex/metabolism, Exocytosis/drug effects, Glutamic Acid/metabolism, Intracellular Signaling Peptides and Proteins, Male, Membrane Proteins, Myristoylated Alanine-Rich C Kinase Substrate, Phosphorylation, Potassium Chloride/pharmacology, Protein Kinase C/metabolism, Proteins/metabolism, Rats, Wistar, Spider Venoms/pharmacology, Synapsins/metabolism, Synaptosomes/metabolism

Relation: https://research.abo.fi/en/publications/6820368b-e9c5-45ed-8328-ed5bfd5a3d71

الاتاحة: https://research.abo.fi/en/publications/6820368b-e9c5-45ed-8328-ed5bfd5a3d71
https://doi.org/10.1016/0014-5793(94)01061-7

المؤلفون: Nicholls, D G, Coffey, E T

المصدر: Nicholls , D G & Coffey , E T 1994 , ' Glutamate exocytosis from isolated nerve terminals ' , Advances in Second Messenger and Phosphoprotein Research , vol. 29 , pp. 189-203 . https://doi.org/10.1016/s1040-7952(06)80016-9

مصطلحات موضوعية: Animals, Calcium/metabolism, Exocytosis/drug effects, Glutamic Acid/metabolism, Isoenzymes/metabolism, Membrane Potentials/physiology, Protein Kinase C/metabolism, Synaptosomes/drug effects

Relation: https://research.abo.fi/en/publications/50cd8860-a46e-4d38-b5c6-df13ad97c45e

الاتاحة: https://research.abo.fi/en/publications/50cd8860-a46e-4d38-b5c6-df13ad97c45e
https://doi.org/10.1016/s1040-7952(06)80016-9

المؤلفون: Mohammad, H, Marchisella, F, Ortega-Martinez, S, Hollos, P, Eerola, K, Komulainen, E, Kulesskaya, N, Freemantle, E, Fagerholm, V, Savontous, E, Rauvala, H, Peterson, B D, van Praag, H, Coffey, E T

المصدر: Molecular Psychiatry; February 2018, Vol. 23 Issue: 2 p362-374, 13p

المؤلفون: Coffey, E. T., Aakerman, K. E. O., Courtney, M. J.

المصدر: Neuroscience Letters; 1997, Vol. 227 Issue: 3 p177-180, 4p

المؤلفون: Mohammad, H, Marchisella, F, Ortega-Martinez, S, Hollos, P, Eerola, K, Komulainen, E, Kulesskaya, N, Freemantle, E, Fagerholm, V, Savontous, E, Rauvala, H, Peterson, B D, van Praag, H, Coffey, E T

المصدر: Molecular Psychiatry; February 2018, Vol. 23 Issue: 2 p487-487, 1p