المؤلفون: Església Catòlica., Papa (1294-1303 : Bonifaci VIII), Bonifaci, S.n., Esglèsia catòlica., Papa (1305-1314 : Climent V).

المساهمون: Església Catòlica., Papa (1294-1303 : Bonifaci VIII), Bonifaci, S.n., Esglèsia catòlica., Papa (1305-1314 : Climent V).

المصدر: Biblioteca Universitat Jaume I. FRXVII70.

مصطلحات موضوعية: Dret canònic

جغرافية الموضوع: Suiza, Basilea

وصف الملف: application/pdf

Relation: 991000590969706336; http://hdl.handle.net/10234/199147

الاتاحة: http://hdl.handle.net/10234/199147

المؤلفون: Escobar-Lopez L., Ochoa J. P., Royuela A., Verdonschot J. A. J., Dal Ferro M., Espinosa M. A., Sabater-Molina M., Gallego-Delgado M., Larranaga-Moreira J. M., Garcia-Pinilla J. M., Basurte-Elorz M. T., Rodriguez-Palomares J. F., Climent V., Bermudez-Jimenez F. J., Mogollon-Jimenez M. V., Lopez J., Pena-Pena M. L., Garcia-Alvarez A., Lopez-Abel B., Ripoll-Vera T., Palomino-Doza J., Bayes-Genis A., Brugada R., Idiazabal U., Mirelis J. G., Dominguez F., Henkens M. T. H. M., Krapels I. P. C., Brunner H. G., Paldino A., Zaffalon D., Mestroni L., Sinagra G., Heymans S. R. B., Merlo M., Garcia-Pavia P.

المساهمون: Escobar-Lopez, L., Ochoa, J. P., Royuela, A., Verdonschot, J. A. J., Dal Ferro, M., Espinosa, M. A., Sabater-Molina, M., Gallego-Delgado, M., Larranaga-Moreira, J. M., Garcia-Pinilla, J. M., Basurte-Elorz, M. T., Rodriguez-Palomares, J. F., Climent, V., Bermudez-Jimenez, F. J., Mogollon-Jimenez, M. V., Lopez, J., Pena-Pena, M. L., Garcia-Alvarez, A., Lopez-Abel, B., Ripoll-Vera, T., Palomino-Doza, J., Bayes-Genis, A., Brugada, R., Idiazabal, U., Mirelis, J. G., Dominguez, F., Henkens, M. T. H. M., Krapels, I. P. C., Brunner, H. G., Paldino, A., Zaffalon, D., Mestroni, L., Sinagra, G., Heymans, S. R. B., Merlo, M., Garcia-Pavia, P.

مصطلحات موضوعية: dilated cardiomyopathy, genetic variant, genetic, genotype, predictor

Relation: info:eu-repo/semantics/altIdentifier/pmid/36109106; info:eu-repo/semantics/altIdentifier/wos/WOS:000863222300001; volume:80; issue:12; firstpage:1115; lastpage:1126; numberofpages:12; journal:JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY; http://hdl.handle.net/11368/3029961; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85137082526; https://www.sciencedirect.com/science/article/pii/S0735109722056042

الاتاحة: http://hdl.handle.net/11368/3029961
https://doi.org/10.1016/j.jacc.2022.06.040
https://www.sciencedirect.com/science/article/pii/S0735109722056042

المؤلفون: Chumillas, S., Maestro García-Donas, María Beatriz, Feliu, J.M., Climent, V.

مصطلحات الفهرس: 577.1, bioelectrocatalysis, CueO, protein voltammetry, oxygen reduction reaction, laccase, Bioquímica (Química), 2403 Bioquímica, journal article, VoR

URL: https://hdl.handle.net/20.500.14352/92588
https://www.frontiersin.org/articles/10.3389/fchem.2018.00358/full
(CTQ2010–18570), (CTQ2016-76221-P)
(UAFPU2013-5796)

المؤلفون: Calvo, M. R., Mares, A. I., Climent, V., van Ruitenbeek, J. M., Untiedt, C.

المصدر: Physica Status Solidi, 204, 1677 - 1685, 2007

مصطلحات موضوعية: Condensed Matter - Mesoscale and Nanoscale Physics, Condensed Matter - Other Condensed Matter

URL الوصول: http://arxiv.org/abs/cond-mat/0610189

المؤلفون: Vallée, M., Moreau, J., Lamarche, I., Barc, C., Kasal-Hoc, N., Mirfendereski, H., Aranzana-Climent, V., Couet, W., Cazenave-Roblot, F., Marchand, S.

المصدر: European Urology ; volume 85, page S127-S128 ; ISSN 0302-2838

الاتاحة: http://dx.doi.org/10.1016/s0302-2838(24)00177-5
https://api.elsevier.com/content/article/PII:S0302283824001775?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0302283824001775?httpAccept=text/plain

المؤلفون: Botello, Luis E.¹ (AUTHOR), Climent, V.¹ (AUTHOR) victor.climent@ua.es, Feliu, J. M.¹ (AUTHOR) juan.feliu@ua.es

المصدر: Journal of Chemical Physics. 12/28/2021, Vol. 155 Issue 24, p1-9. 9p.

مصطلحات موضوعية: *ELECTRIC double layer, *HYDROGEN economy, *THERMODYNAMICS, *BOND energy (Chemistry), *THERMODYNAMIC functions, *HYDROGEN production

المؤلفون: Lopez-Sainz, A, Dominguez, F, Lopes, LR, Ochoa, JP, Barriales-Villa, R, Climent, V, Linschoten, M, Tiron, C, Chiriatti, C, Marques, N, Rasmussen, TB, Espinosa, MÁ, Beinart, R, Quarta, G, Cesar, S, Field, E, Garcia-Pinilla, JM, Bilinska, Z, Muir, AR, Roberts, AM, Santas, E, Zorio, E, Peña-Peña, ML, Navarro, M, Fernandez, A, Palomino-Doza, J, Azevedo, O, Lorenzini, M, García-Álvarez, MI, Bento, D, Jensen, MK, Méndez, I, Pezzoli, L, Sarquella-Brugada, G, Campuzano, O, Gonzalez-Lopez, E, Mogensen, J, Kaski, JP, Arad, M, Brugada, R, Asselbergs, FW, Monserrat, L, Olivotto, I, Elliott, PM, Garcia-Pavia, P, European Genetic Cardiomyopathies Initiative Investigators

المصدر: Journal of the American College of Cardiology , 76 (2) pp. 186-197. (2020)

مصطلحات موضوعية: PRKAG2, glycogen-storage disease, heart failure, hypertrophic cardiomyopathy, left ventricular hypertrophy, pacemaker, pre-excitation, sudden cardiac death

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10105226/3/Syrris_Clinical%20Features%20and%20Natural%20History%20of%20PRKAG2%20Variant%20Cardiac%20Glycogenosis.pdf; https://discovery.ucl.ac.uk/id/eprint/10105226/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10105226/3/Syrris_Clinical%20Features%20and%20Natural%20History%20of%20PRKAG2%20Variant%20Cardiac%20Glycogenosis.pdf
https://discovery.ucl.ac.uk/id/eprint/10105226/

المؤلفون: Salazar-Mendiguchía, J, Ochoa, JP, Palomino-Doza, J, Domínguez, F, Díez-López, C, Akhtar, M, Ramiro-León, S, Clemente, MM, Pérez-Cejas, A, Robledo, M, Gómez-Díaz, I, Peña-Peña, ML, Climent, V, Salmerón-Martínez, F, Hernández, C, García-Granja, PE, Mogollón, MV, Cárdenas-Reyes, I, Cicerchia, M, García-Giustiniani, D, Lamounier, A, Gil-Fournier, B, Díaz-Flores, F, Salguero, R, Santomé, L, Syrris, P, Olivé, M, García-Pavía, P, Ortiz-Genga, M, Elliott, PM, Monserrat, L, GENESCOPIC Research Group, .

المصدر: Heart (2020) (In press).

وصف الملف: text

Relation: https://discovery.ucl.ac.uk/id/eprint/10099140/1/Elliott_Mutations%20in%20TRIM63%20cause%20an%20autosomal-recessive%20form%20of%20hypertrophic%20cardiomyopathy_AOP.pdf; https://discovery.ucl.ac.uk/id/eprint/10099140/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10099140/1/Elliott_Mutations%20in%20TRIM63%20cause%20an%20autosomal-recessive%20form%20of%20hypertrophic%20cardiomyopathy_AOP.pdf
https://discovery.ucl.ac.uk/id/eprint/10099140/

المؤلفون: Aranzana-Climent, V, Buyck, J M, Smani, Y, Pachón-Diaz, J, Marchand, S, Couet, W, Grégoire, N

مصطلحات موضوعية: Acinetobacter baumannii, Combinations, GPDI, Minocycline, PK/PD modelling, Polymyxin B, Anti-Bacterial Agents, Drug Resistance, Bacterial, Models, Biological

Relation: http://hdl.handle.net/10668/15028; http://www.clinicalmicrobiologyandinfection.com/article/S1198743X20300422/pdf

الاتاحة: http://hdl.handle.net/10668/15028
https://doi.org/10.1016/j.cmi.2020.01.017
http://www.clinicalmicrobiologyandinfection.com/article/S1198743X20300422/pdf

المؤلفون: Armiñanzas, C., Fariñas-Alvarez, C., Zarauza, J., Muñoz, P., González Ramallo, V., Martínez Sellés, M., Miró Meda, J.M., Pericás, J.M., Goenaga, M.Á., Ojeda Burgos, G., Rodríguez Álvarez, R., Castelo Corral, L., Gálvez-Acebal, J., Martínez Marcos, F.J., Fariñas, M.C., Fernández Sánchez, F., Noureddine, M., Rosas, G., de la Torre Lima, J., Aramendi, J., Bereciartua, E., Blanco, M.J., Blanco, R., Boado, M.V., Campaña Lázaro, M., Crespo, A., Goikoetxea, J., Iruretagoyena, J.R., Irurzun Zuazabal, J., López-Soria, L., Montejo, M., Nieto, J., Rodrigo, D., Rodríguez, D., Rodríguez, R., Vitoria, Y., Voces, R., García López, M.V., Georgieva, R.I., Ojeda, G., Rodríguez Bailón, I., Ruiz Morales, J., Cuende, A.M., Echeverría, T., Fuerte, A., Gaminde, E., Idígoras, P., Iribarren, J.A., Izaguirre Yarza, A., Kortajarena Urkola, X., Reviejo, C., Carrasco, R., Climent, V., Llamas, P., Merino, E., Plazas, J., Reus, S., Álvarez, N., Bravo-Ferrer, J.M., Castelo, L., Cuenca, J., Llinares, P., Miguez Rey, E., Rodríguez Mayo, M., Sánchez, E., Sousa Regueiro, D., Martínez, F.J., Alonso, M.D.M., Castro, B., García Rosado, D., Durán, M.D.C., Miguel Gómez, M.A., Lacalzada, J., Nassar, I., Plata Ciezar, A., Reguera Iglesias, J.M., Asensi Álvarez, V., Costas, C., de la Hera, J., Fernández Suárez, J., Iglesias Fraile, L., León Arguero, V., López Menéndez, J., Mencia Bajo, P., Morales, C., Moreno Torrico, A., Palomo, C., Paya Martínez, B., Rodríguez Esteban, Á., Rodríguez García, R., Telenti Asensio, M., Almela, M., Ambrosioni, J., Azqueta, M., Brunet, M., Bodro, M., Cartañá, R., Falces, C., Fita, G., Fuster, D., García de la Mària, C., Hernández-Meneses, M., Llopis Pérez, J., Marco, F., Miró, J.M., Moreno, A., Nicolás, D., Ninot, S., Quintana, E., Paré, C., Pereda, D., Pomar, J.L., Ramírez, J., Rovira, I., Sandoval, E., Sitges, M., Soy, D., Téllez, A., Tolosana, J.M., Vidal, B., Vila, J., Adán, I., Bermejo, J., Bouza, E., Celemín, D., Cuerpo Caballero, G., Delgado Montero, A., Fernández Cruz, A., García Mansilla, A., García Leoni, M.E., Kestler Hernández, M., Hualde, A.M., Marín, M., Martínez-Sellés, M., Menárguez, M.C., Rincón, C., Rodríguez-Abella, H., Rodríguez-Créixems, M., Pinilla, B., Pinto, Á., Valerio, M., Vázquez, P., Verde Moreno, E., Antorrena, I., Loeches, B., Martín Quirós, A., Moreno, M., Ramírez, U., Rial Bastón, V., Romero, M., Saldaña, A., Agüero Balbín, J., Amado, C., Armiñanzas Castillo, C., Arnaiz García, A., Cobo Belaustegui, M., Fariñas-Álvarez, C., Gómez Izquierdo, R., García, I., González-Rico, C., Gutiérrez-Cuadra, M., Gutiérrez Díez, J., Pajarón, M., Parra, J.A., Sarralde, A., Teira, R., Domínguez, F., García Pavía, P., González, J., Orden, B., Ramos, A., Centella, T., Hermida, J.M., Moya, J.L., Martín-Dávila, P., Navas, E., Oliva, E., del Río, A., Ruiz, S., Hidalgo Tenorio, C., Almendro Delia, M., Araji, O., Barquero, J.M., Calvo Jambrina, R., de Cueto, M., Gálvez Acebal, J., Méndez, I., Morales, I., Matamala Adell, M.

وصف الملف: application/pdf

Relation: http://zaguan.unizar.es/record/88275

الاتاحة: http://zaguan.unizar.es/record/88275
https://doi.org/10.1016/j.ejim.2019.03.006

المؤلفون: Becker, K., Aranzana-Climent, V., Cao, S., Nilsson, A., Shariatgorji, R., Haldimann, K., Platzack, Björn, Hughes, D., Andrén, P. E., Böttger, E. C., Friberg, L. E., Hobbie, S. N., consortium, the ENABLE

المصدر: Clinical Microbiology and Infection. 27(9):1315

مصطلحات موضوعية: Acinetobacter baumannii, Apramycin, Carbapenem-resistant, EBL-1003, In vivo efficacy, Probability of target attainment, Pulmonary infection

وصف الملف: print

URL الوصول: https://urn.kb.se/resolve?urn=urn:nbn:se:ri:diva-51934
https://doi.org/10.1016/j.cmi.2020.12.004

المؤلفون: Chumillas, S., Maestro García-Donas, María Beatriz, Feliu, J.M., Climent, V.

مصطلحات موضوعية: 577.1, bioelectrocatalysis, CueO, protein voltammetry, oxygen reduction reaction, laccase, Bioquímica (Química), 2403 Bioquímica

وصف الملف: application/pdf

Relation: (CTQ2010–18570), (CTQ2016-76221-P); (UAFPU2013-5796); https://hdl.handle.net/20.500.14352/92588; https://www.frontiersin.org/articles/10.3389/fchem.2018.00358/full

الاتاحة: https://hdl.handle.net/20.500.14352/92588
https://doi.org/10.3389/fchem.2018.00358
https://www.frontiersin.org/articles/10.3389/fchem.2018.00358/full

المؤلفون: Ortiz-Genga MF, Cuenca S, Dal Ferro M, Zorio E, Salgado-Aranda R, Climent V, Padrón-Barthe L, Duro-Aguado I, Jiménez-Jáimez, Hidalgo-Olivares VM, García-Campo E, Lanzillo C, Suárez-Mier MP, Yonath H, Marcos-Alonso S, Ochoa JP, Santomé JL, García-Giustiniani D, Rodríguez-Garrido JL, Domínguez F, Merlo M, Palomino J, Peña ML, Trujillo JP, Martín-Vila A, Stolfo D, Molina P, Lara-Pezzi E, Calvo-Iglesias FE, Nof E, Calò L, Barriales-Villa, Gimeno-Blanes JR, Arad M, García-Pavía P, Monserrat L

المساهمون: Ortiz-Genga, Mf, Cuenca, S, Dal Ferro, M, Zorio, E, Salgado-Aranda, R, Climent, V, Padrón-Barthe, L, Duro-Aguado, I, Jiménez-Jáimez, Hidalgo-Olivares, Vm, García-Campo, E, Lanzillo, C, Suárez-Mier, Mp, Yonath, H, Marcos-Alonso, S, Ochoa, Jp, Santomé, Jl, García-Giustiniani, D, Rodríguez-Garrido, Jl, Domínguez, F, Merlo, M, Palomino, J, Peña, Ml, Trujillo, Jp, Martín-Vila, A, Stolfo, D, Molina, P, Lara-Pezzi, E, Calvo-Iglesias, Fe, Nof, E, Calò, L, Barriales-Villa, Gimeno-Blanes, Jr, Arad, M, García-Pavía, P, Monserrat, L

مصطلحات موضوعية: filamin C, filaminopathy, genotype, prognosi, sudden death, ventricular arrhythmia

وصف الملف: STAMPA

Relation: info:eu-repo/semantics/altIdentifier/pmid/27908349; info:eu-repo/semantics/altIdentifier/wos/WOS:000389592000007; volume:68; issue:22; firstpage:2440; lastpage:2451; numberofpages:12; journal:JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY; http://hdl.handle.net/11368/2966582; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84999622133; https://www.sciencedirect.com/science/article/pii/S0735109716364166?via=ihub

الاتاحة: http://hdl.handle.net/11368/2966582
https://doi.org/10.1016/j.jacc.2016.09.927
https://www.sciencedirect.com/science/article/pii/S0735109716364166?via=ihub

المؤلفون: Escobar-Lopez, L., Ochoa, J.P., Royuela, A., Verdonschot, J.A.J., Ferro, M., Espinosa, M.A., Sabater-Molina, M., Gallego-Delgado, M., Larrañaga-Moreira, J.M., Garcia-Pinilla, J.M., Basurte-Elorz, M.T., Rodríguez-Palomares, J.F., Climent, V., Bermudez-Jimenez, F.J., Mogollón-Jiménez, M.V., Lopez, J., Peña-Peña, M.L., Garcia-Alvarez, A., López-Abel, B., Ripoll-Vera, T., Palomino-Doza, J., Bayes-Genis, A., Brugada, R., Idiazabal, U., Mirelis, J.G., Dominguez, F., Henkens, M., Krapels, I.P.C., Brunner, H.G., Paldino, A., Zaffalon, D., Mestroni, L., Sinagra, G., Heymans, S.R.B., Merlo, M., Garcia-Pavia, P.

المصدر: Journal of the American College of Cardiology; 1115; 1126; 0735-1097; 12; 80; ~Journal of the American College of Cardiology~1115~1126~~~0735-1097~12~80~~

URL: https://repository.ubn.ru.nl//bitstream/handle/2066/284808/284808.pdf
https://repository.ubn.ru.nl/handle/2066/284808
https://doi.org/10.1016/j.jacc.2022.06.040

المؤلفون: Fontanier, T., Lamarche, I., Barc, C., Aranzana-Climent, V., Mirfendereski, H., Kasal-Hoc, N., Cazenave-Roblot, F., Marchand, S., Vallée, M.

المصدر: Proges en Urologie; 2024 Supplement, Vol. 34, pS134-S135, 2p

المؤلفون: Savelev, A., Moscicki, R., Mata Caballero, R., Jacobs, J., Popa, O-A, Siliste, RN., Rivin, AE., Rud, SD., Climent, V., Feliu, E., Vicedo, A., Saavedra, J., Lopez Pais, J., Molina, L., Gorriz, J., Hernandez Jimenez, V., Perea, J., Forteza, A., Esteban, C., Alonso Martin, J., Van Berendoncks, AM., Van Herck, JL., Vergauwen, W., Spinhoven, MJ., Lauwers, P., Tjalma, WA., Dorobantu, L., Chioncel, O., Stiru, O., Herlea, V., Bulescu, C., Lacau, S., Iliescu, V., Ginghina, C., Ciudin, R., Ciomag, R., Homentcovschi, C., Saguna, C., Spataru, D.

المصدر: European Heart Journal – Cardiovascular Imaging ; volume 17, issue suppl 2, page ii3-ii5 ; ISSN 2047-2404 2047-2412

الاتاحة: https://doi.org/10.1093/ehjci/jew231
http://academic.oup.com/ehjcimaging/article-pdf/17/suppl_2/ii3/9987997/jew231.pdf

المؤلفون: Hernández‐Romero, D., Orenes‐Piñero, E., García‐Honrubia, A., Climent, V., Romero‐Aniorte, A. I., Martínez, C. M., García‐Bautista, M., Martínez, M., Feliu, E., González, J., Cánovas, S., Montero‐Argudo, J. A., Valdés, M., Marín, F.

المساهمون: Instituto de Salud Carlos III, FEDER, Department of Molecular Biology, Centro Inmunológico de Alicante, Instituto Murciano de Investigaciones Biosanitarias Virgen de la Arrixaca

المصدر: Journal of Internal Medicine ; volume 278, issue 1, page 50-58 ; ISSN 0954-6820 1365-2796

الاتاحة: http://dx.doi.org/10.1111/joim.12334
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fjoim.12334
https://onlinelibrary.wiley.com/doi/pdf/10.1111/joim.12334

المؤلفون: Vallée, M., Moreau, J., Fontanier, T., Lamarche, I., Mirfendereski, H., Aranzan-Climent, V., Barc, C., Kasal-Hoc, N., Couet, W., Cazenave-Roblot, F., Marchand, S.

المصدر: Progrès en Urologie - FMC; November 2024, Vol. 34 Issue: 7, Number 7 Supplement 1 pS127-S128, 2p

المؤلفون: Akhtar, MM, Lorenzini, M, Pavlou, M, Ochoa, JP, O'Mahony, C, Restrepo-Cordoba, MA, Segura-Rodriguez, D, Bermudez-Jimenez, F, Molina, P, Cuenca, S, Ader, F, Larranaga-Moreira, JM, Sabater-Molina, M, Garcia-Alvarez, MI, Arantzamendi, LG, Truszkowska, G, Ortiz-Genga, M, Ruiz, IS, Nielson, SK, Rasmussen, TB, Robles Mezcua, A, Alvarez-Rubio, J, Eiskjaer, H, Gautel, M, Garcia-Pinilla, JM, Ripoll-Vera, T, Mogensen, J, Limeres Freire, J, Rodriguez-Palomares, JF, Pena-Pena, ML, Rangel-Sousa, D, Palomino-Doza, J, Arana Achaga, X, Bilinska, Z, Zamarreno Golvano, E, Climent, V, Penalver, MN, Barriales-Villa, R, Charron, P, Yotti, R, Zorio, E, Jimenez-Jaimez, J, Garcia-Pavia, P, Elliott, PM

المصدر: JAMA Cardiology (2021) (In press).

Relation: https://discovery.ucl.ac.uk/id/eprint/10128902/

الاتاحة: https://discovery.ucl.ac.uk/id/eprint/10128902/

المؤلفون: Escobar López, Luis, Ochoa, JP, García Mirelis, J, Espinosa, MA, Navarro, M, Gallego Delgado, M, Barriales Villa, R, Robles Mezcua, A, Basurte Elorz, MT, Gutiérrez García-Moreno, L, Climent, V, Jiménez Jaimez, J, Mogollón Jiménez, MV, Lopez, J, Peña Peña, ML, García Alvarez, A, Brion, M, Ripoll Vera, T, Palomino Doza, J, Tirón, C, Idiazabal, U, Noel Brogger, M, García Hernandez, S, Restrepo Córdoba, MA, González López, E, Mendez, I, Sabater, M, Villacorta, E, Larrañaga Moreira, JM, Abecia, A, Fernández, AI, García Pinilla, JM, Rodríguez Palomares, JF, Gimeno Blanes, JR, Bayes Genis, A, Lara Pezzi, E, Dominguez, F, García-Pavía, Pablo

المصدر: J Am Coll Cardiol, 78(17), 1682-1699, (2021)

مصطلحات موضوعية: Adult, Aged, Arrhythmias, Cardiac, Cardiomyopathy, dilated, Female, Genetic Variation, Genotype, Heart Failure, Heart Venticles, Humans, Longitudinal studies, Male, Middle Aged, Retrospective Studies, Risk, Stroke Volume, Treatment outcome, Ventricular Dysfunction, Ventricular Function

Relation: https://doi.org/10.1016/j.jacc.2021.08.039; oai:zenodo.org:13951091

الاتاحة: https://doi.org/10.1016/j.jacc.2021.08.039