المؤلفون: Kai Kruse, Clemens B. Hug, Juan M. Vaquerizas

المصدر: Genome Biology, Vol 21, Iss 1, Pp 1-19 (2020)

مصطلحات موضوعية: Chromosome conformation capture, Hi-C, Hi-C analysis, Topologically associating domains (TAD), Chromosomal compartments, Chromatin loops, Biology (General), QH301-705.5, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1474-760X

URL الوصول: https://doaj.org/article/aa7f65e045db4daea184045b6c38d1dd

المؤلفون: Bradley T. Hyman, Nathan T. Johnson, Sarah A. Boswell, Mark W. Albers, Kyle Evans, George Zhou, Artem Sokolov, Clemens B. Hug, Steven Rodriguez, Peter K. Sorger, Nienke Moret, Petar Todorov

المصدر: Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Prescription Drugs, Polypharmacology, Science, Primary Cell Culture, MEDLINE, General Physics and Astronomy, Nerve Tissue Proteins, Disease, Machine learning, computer.software_genre, Severity of Illness Index, Article, General Biochemistry, Genetics and Molecular Biology, Machine Learning, Food and drug administration, 03 medical and health sciences, 0302 clinical medicine, Alzheimer Disease, Humans, Medicine, Nootropic Agents, Repurposing, Cerebral Cortex, Neurons, Pharmacology, Multidisciplinary, business.industry, Gene Expression Profiling, Drug Repositioning, Drugs, Investigational, General Chemistry, Alzheimer's disease, High-Throughput Screening Assays, Clinical trial, Drug repositioning, Neuroprotective Agents, 030104 developmental biology, Gene Expression Regulation, Pharmacogenetics, Biomarker (medicine), Identification (biology), Artificial intelligence, business, computer, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad68ff5f7983e8e48180f85eeb89cb1a
https://doaj.org/article/93e763bd3055417ea9c559a7b6fa24d5

المؤلفون: Brian S. White, Yury Goltsev, Clemens B. Hug, Erik A. Burlingame, Artem Sokolov, Juan C. Vizcarra, Darren R. Tyson, Csbc

المصدر: Comput Med Imaging Graph

مصطلحات موضوعية: Diagnostic Imaging, Data processing, Radiological and Ultrasound Technology, Computer science, ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION, Image registration, Health Informatics, Computer Graphics and Computer-Aided Design, Data science, Field (computer science), Article, Image (mathematics), Identification (information), Cancer systems biology, Neoplasms, Image Processing, Computer-Assisted, Tumor Microenvironment, Humans, Radiology, Nuclear Medicine and imaging, Segmentation, Computer Vision and Pattern Recognition, Dissemination, Software

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0764f76f0e9aa4385a4f879de99cd5
https://pubmed.ncbi.nlm.nih.gov/34864359

المؤلفون: Nienke Moret, Mark W. Albers, Artem Sokolov, Steven Rodriguez, George Zhou, B. T. Hyman, Petar Todorov, Peter K. Sorger, Nathan T. Johnson, Clemens B. Hug, Sarah A. Boswell, Kyle Evans

مصطلحات موضوعية: business.industry, Disease, Machine learning, computer.software_genre, Biomarker (cell), Clinical trial, Drug repositioning, Gene nomenclature, New chemical entity, Medicine, Identification (biology), Artificial intelligence, business, computer, Repurposing

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::91f2eb35efdb612c915ea1f8f6803134
https://doi.org/10.1101/2020.05.15.098749

المؤلفون: Clemens B. Hug, Juan M. Vaquerizas, Kai Kruse

المصدر: Genome Biology
Genome Biology, Vol 21, Iss 1, Pp 1-19 (2020)

مصطلحات موضوعية: lcsh:QH426-470, Hi-C analysis, Molecular Conformation, Biology, computer.software_genre, Chromosomes, Chromosome conformation capture, 03 medical and health sciences, 0302 clinical medicine, Hi-C, Chromosomal compartments, Humans, Matrix analysis, Feature set, lcsh:QH301-705.5, Embryonic Stem Cells, 030304 developmental biology, computer.programming_language, Chromatin loops, 0303 health sciences, Small number, Hi-C visualisation, Computational Biology, High-Throughput Nucleotide Sequencing, Genomics, Python (programming language), Topologically associating domains (TAD), Chromatin, Visualization, lcsh:Genetics, lcsh:Biology (General), Data mining, Analysis tools, computer, 030217 neurology & neurosurgery, Software

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::656cbcfd23147b3eac2bcc8dd3281fe4
https://pubmed.ncbi.nlm.nih.gov/33334380

المؤلفون: Clemens B, Hug, Juan M, Vaquerizas

المصدر: Journal of Visualized Experiments : JoVE

مصطلحات موضوعية: Cell Nucleus, animal structures, Protein Conformation, fungi, embryo, Genomics, Issue 140, topologically associating domain, Chromatin, fly, Drosophila melanogaster, chromatin architecture, Hi-C, chromatin conformation capture, Genetics, Animals, Gene Library

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::de8cb1242f73468849513cf4f77cf1af
https://pubmed.ncbi.nlm.nih.gov/30346395

المؤلفون: Alla Berezovskaya, Frank J. T. Staal, Laura Garcia-Perez, Evisa Gjini, Brian J. Abraham, Traci M. Blonquist, Alejandro Gutierrez, David M. Langenau, Richard A. Young, Karin Pike-Overzet, Shuning He, Qin Tang, A. Thomas Look, Donna Neuberg, Lars Anders, Clemens B. Hug, Zhaodong Li, Takaomi Sanda, Leonard I. Zon, Sunniyat Rahman, Marc R. Mansour, Theresa E. Leon, Adele K. Fielding, Mark W. Zimmerman, Riadh Lobbardi, Youyi Kuang, Yi Zhou

المساهمون: Massachusetts Institute of Technology. Department of Biology, Young, Richard A

المصدر: Journal of Experimental Medicine
Journal of Experimental Medicine, 215(7), 1929-1945
The Journal of Experimental Medicine
Rockefeller University Press

مصطلحات موضوعية: 0301 basic medicine, Apoptosis, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Dexamethasone, Small hairpin RNA, Mice, hemic and lymphatic diseases, Transcriptional regulation, Immunology and Allergy, MCL1, Zebrafish, Research Articles, Gene knockdown, Thymocytes, Gene Expression Regulation, Leukemic, 3. Good health, Enhancer Elements, Genetic, Treatment Outcome, medicine.anatomical_structure, Child, Preschool, Protein Binding, animal structures, Cell Survival, T cell, Immunology, Biology, Response Elements, Article, Proto-Oncogene Proteins c-myc, 03 medical and health sciences, medicine, Animals, Humans, Glucocorticoids, Transcription factor, Cell Proliferation, Base Sequence, Oncogene, Infant, Oncogenes, Zebrafish Proteins, biology.organism_classification, Repressor Proteins, Disease Models, Animal, Mutagenesis, Insertional, 030104 developmental biology, Cancer research, Myeloid Cell Leukemia Sequence 1 Protein, Neoplasm Transplantation

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169707fdca479f4a91f17500bd6300a9
https://doi.org/10.1084/jem.20170484

المؤلفون: Jonas Bittern, Li Zhang, Marina Wagner, Moushami Mallik, Hannes C.A. Drexler, Martijn A. Huynen, Marica Catinozzi, Christian Klämbt, Sina Mersmann, Juan M. Vaquerizas, Erik Storkebaum, Clemens B. Hug, Julia Bussmann

المصدر: Journal of Cell Biology, 217, 3947-3964
The Journal of Cell Biology
Journal of Cell Biology, 217, 11, pp. 3947-3964

مصطلحات موضوعية: 0301 basic medicine, Regulation of gene expression, Mutation, Gene knockdown, Mutant, Metabolic Disorders Radboud Institute for Molecular Life Sciences [Radboudumc 6], Cell Biology, Biology, medicine.disease_cause, Article, Cell biology, Loss of heterozygosity, 03 medical and health sciences, 030104 developmental biology, Gene expression, medicine, Gene Knockdown Techniques, Research Articles, TAF15, Molecular Neurobiology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::026f6c39e100671b6e5e580f350e60b1
http://hdl.handle.net/2066/197913

المؤلفون: Juan M. Vaquerizas, Clemens B. Hug, Benjamín Hernández-Rodríguez, Kai Kruse

المصدر: Bioinformatics

مصطلحات موضوعية: 0301 basic medicine, Statistics and Probability, Genome, Computer science, business.industry, Python (programming language), Genome Analysis, Applications Notes, Biochemistry, Computer Science Applications, 03 medical and health sciences, Computational Mathematics, 030104 developmental biology, Software, Computational Theory and Mathematics, Animals, Humans, business, Molecular Biology, computer, Algorithm, Algorithms, computer.programming_language

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f2fa576235da843f55d5dc8fb267afe

المؤلفون: Juan M. Vaquerizas, Alexis Grimaldi, Kai Kruse, Clemens B. Hug

المصدر: Cell. 169:216-228.e19

مصطلحات موضوعية: 0301 basic medicine, Genetics, Drosophila embryogenesis, RNA polymerase II, Biology, Genome, General Biochemistry, Genetics and Molecular Biology, Chromatin, Cell biology, 03 medical and health sciences, 030104 developmental biology, biology.protein, Maternal to zygotic transition, Gene, Transcription factor, Genomic organization

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::16c0bc91496e21ddc09dcc9ee9580be9
https://doi.org/10.1016/j.cell.2017.03.024

المؤلفون: Juan M. Vaquerizas, Clemens B. Hug

المصدر: Trends in Genetics

مصطلحات موضوعية: Male, 0301 basic medicine, Zygote, Molecular Conformation, Embryonic Development, Biology, Genome, Epigenesis, Genetic, Mice, 03 medical and health sciences, Transcription (biology), Gene expression, Genetics, Animals, Epigenetics, Regulation of gene expression, Gene Expression Regulation, Developmental, Spermatozoa, Chromatin, Drosophila melanogaster, 030104 developmental biology, Evolutionary biology, Oocytes, Maternal to zygotic transition, Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::519b549a8180235f3bc3c333adef7fe8