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المؤلفون: Mina Azimi, Sook Wah Yee, Andrew Riselli, Dina Buitrago Silva, Craig P. Giacomini, Kathleen M. Giacomini, Claire M. Brett
المصدر: Journal of Veterinary Pharmacology and Therapeutics.
مصطلحات موضوعية: Pharmacology, General Veterinary
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المؤلفون: Dan M. Roden, Joel Mefford, Radojka M. Savic, Wen Cc, Sook Wah Yee, Kathleen M. Giacomini, Srijib Goswami, Sophie L. Stocker, Monique M. Hedderson, Jonathan D. Mosley, Claire M. Brett, John S. Witte, Robert L. Davis, Xiaomin Liang, Richard A. Castro, M. D. Simpson, Michiaki Kubo, Shiro Maeda
المصدر: Clinical pharmacology and therapeutics, vol 96, iss 3
مصطلحات موضوعية: Male, endocrine system diseases, Genome-wide association study, Type 2 diabetes, Models, 80 and over, Pharmacology (medical), Pharmacology & Pharmacy, Aged, 80 and over, education.field_of_study, Diabetes, Homozygote, Single Nucleotide, Pharmacology and Pharmaceutical Sciences, Middle Aged, Metformin, Hepatocyte nuclear factors, Phenotype, Treatment Outcome, Hepatocyte Nuclear Factor 4, Female, Type 2, medicine.drug, Adult, medicine.medical_specialty, Sp1 Transcription Factor, Population, Biology, Models, Biological, Polymorphism, Single Nucleotide, Article, Young Adult, Clinical Research, Internal medicine, Diabetes Mellitus, Genetics, medicine, Humans, Hypoglycemic Agents, PPAR alpha, Polymorphism, education, Transcription factor, Metabolic and endocrine, Aged, Retrospective Studies, Glycated Hemoglobin, Pharmacology, Sp1 transcription factor, Human Genome, nutritional and metabolic diseases, Biological, medicine.disease, United States, Endocrinology, Diabetes Mellitus, Type 2, Pharmacogenetics, Multivariate Analysis, Biomarkers, Genome-Wide Association Study, Transcription Factors
وصف الملف: application/pdf
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المؤلفون: Peter J. Davis, Claire M. Brett
المصدر: Smith's Anesthesia for Infants and Children ISBN: 9780323341257
مصطلحات موضوعية: medicine.medical_specialty, business.industry, Anesthesia, medicine, business, Surgery
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المؤلفون: Ann G. Bailey, Jeffrey R. Balzer, Victor C. Baum, David S. Beebe, Sue R. Beers, Kumar G. Belani, Bruno Bissonette, Brian Blasiole, Adrian T. Bosenberg, Barbara W. Brandom, Claire M. Brett, James G. Cain, Thomas M. Chalifoux, Franklyn P. Cladis, David E. Cohen, Ira T. Cohen, Joseph P. Cravero, Nicholas M. Dalesio, Andrew Davidson, Jessica Davis, Peter J. Davis, Duncan G. de Souza, Nina Deutsch, Laura K. Diaz, James A. DiNardo, Peter F. Ehrlich, Demetrius Ellis, James J. Fehr, Jeffrey M. Feldman, Kathryn Felmet, Jonathan D. Finder, Sean Flack, Randall P. Flick, Michelle A. Fortier, Geoff Frawley, Samir K. Gadepalli, Jeffrey L. Galinkin, Nancy Glass, Salvatore R. Goodwin, George A. Gregory, Lorelei Grunwaldt, Padma Gulur, Nina A. Guzzetta, Dawit T. Haile, Denise M. Hall-Burton, Gregory B. Hammer, Jennifer L. Hamrick, Justin T. Hamrick, Daniel M. Hayward, Eugenie S. Heitmiller, Andrew Herlich, Robert S. Holzman, Vincent C. Hsieh, Elizabeth A. Hunt, James W. Ibinson, Lori T. Justice, Zeev N. Kain, Evan Kharasch, Rahul Koka, Sabine Kost-Byerly, Elliot J. Krane, Barry D. Kussman, Robert Scott Lang, Helen Victoria Lauro, Jennifer K. Lee, Joseph Losee, Igor Luginbuehl, Mohamed Mahmoud, Brian Martin, Keira P. Mason, William J. Mauermann, Lynne G. Maxwell, Francis X. McGowan, Bruce E. Miller, Constance L. Monitto, Philip G. Morgan, Michael L. Moritz, Etsuro K. Motoyama, Michael E. Nemergut, Julie Niezgoda, Shelley Ohliger, Phillip M.T. Pian, David M. Polaner, George D. Politis, Andrew J. Powell, Paul Reynolds, Karene Ricketts, Richard S. Ro, Mark A. Rockoff, Thomas Romanelli, Nancy Bard Samol, Paul J. Samuels, Joseph A. Scattoloni, Jamie McElrath Schwartz, Deborah A. Schwengel, Victor L. Scott, Donald H. Shaffner, Avinash C. Shukla, Allan F. Simpao, Erica L. Sivak, Matthew D. Sjoblom, Kyle Soltys, Sulpicio G. Soriano, Eric T. Stickles, Jennifer M. Thomas, Stevan P. Tofovic, Kha M. Tran, Premal M. Trivedi, Robert D. Valley, Monica S. Vavilala, Lisa Vecchione, Keith M. Vogt, Jeffrey R. Wahl, Kerri M. Wahl, Ari Y. Weintraub, Timothy P. Welch, Robert K. Williams, Eric P. Wittkugel, Susan Woelfel, Myron Yaster, Koichi Yuki, Steven Zgleszewski, Basil J. Zitelli, Aaron L. Zuckerberg
المصدر: Smith's Anesthesia for Infants and Children ISBN: 9780323341257
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المؤلفون: Sophie L. Stocker, Kathleen M. Giacomini, Yong Huang, Jennifer E. Hibma, Srijib Goswami, Richard A. Castro, Matthias B. Wittwer, Ron J. Keizer, Arik A. Zur, Xuexiang Zhang, Sook Wah Yee, Radojka M. Savic, Claire M. Brett
المصدر: Clinical pharmacokinetics, vol 55, iss 6
مصطلحات موضوعية: 0301 basic medicine, Blood Glucose, Male, Kidney Disease, Pharmacology, 030226 pharmacology & pharmacy, 0302 clinical medicine, Pharmacology (medical), Pharmacology & Pharmacy, media_common, Organic cation transport proteins, Cross-Over Studies, biology, Pharmacology and Pharmaceutical Sciences, Famotidine, Metformin, 5.1 Pharmaceuticals, Creatinine, Area Under Curve, 6.1 Pharmaceuticals, Female, Patient Safety, Drug, Development of treatments and therapeutic interventions, medicine.drug, Adult, Organic Cation Transport Proteins, media_common.quotation_subject, Article, Dose-Response Relationship, 03 medical and health sciences, Young Adult, Pharmacotherapy, Pharmacokinetics, medicine, Humans, Hypoglycemic Agents, Cimetidine, Dose-Response Relationship, Drug, business.industry, Evaluation of treatments and therapeutic interventions, Anti-Ulcer Agents, Crossover study, 030104 developmental biology, biology.protein, business
وصف الملف: application/pdf
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المؤلفون: Claire M. Brett, Danton Charr
المصدر: Gregory's Pediatric Anesthesia
مصطلحات موضوعية: medicine.medical_specialty, business.industry, medicine, Developmental physiology, Intensive care medicine, business, Hyponatremia, medicine.disease
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المؤلفون: Ying Chen, Ligong Chen, Yong Huang, Maya K. Leabman, Shuanglian Li, Chaline Brown, Sook Wah Yee, Richard A. Castro, Thomas J. Urban, Claire M. Brett, Ji Ha Choi, Stephen Cheatham, Kathleen M. Giacomini, Esteban G. Burchard
المصدر: Pharmacogenetics and Genomics. 19:497-504
مصطلحات موضوعية: Kidney, Organic cation transport proteins, SLC47A1, endocrine system diseases, biology, nutritional and metabolic diseases, Kidney metabolism, Metformin, medicine.anatomical_structure, Renal Elimination, Biochemistry, Pharmacokinetics, Genetic variation, Genetics, medicine, biology.protein, Molecular Medicine, General Pharmacology, Toxicology and Pharmaceutics, Molecular Biology, Genetics (clinical), medicine.drug
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المؤلفون: Chaline Brown, Yong Huang, Kathleen M. Giacomini, Thomas J. Urban, Claire M. Brett, N Shah, Richard A. Castro, Esteban G. Burchard, R Mercer
المصدر: Clinical Pharmacology & Therapeutics. 83:416-421
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Adolescent, Cyclohexanecarboxylic Acids, Gabapentin, Metabolic Clearance Rate, Phenylalanine, medicine.medical_treatment, Analgesic, Renal function, Pharmacology, Cell Line, Cohort Studies, Pharmacokinetics, Leucine, Reference Values, Internal medicine, medicine, Humans, Pharmacology (medical), Amines, gamma-Aminobutyric Acid, Kidney, Polymorphism, Genetic, Organic cation transport proteins, biology, Chemistry, Organic Cation Transporter 1, Genetic Variation, Apical membrane, Kidney Tubules, medicine.anatomical_structure, Endocrinology, Anticonvulsant, biology.protein, Female, Glomerular Filtration Rate, medicine.drug
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9Effect of Genetic Variation in the Organic Cation Transporter 1, OCT1, on Metformin Pharmacokinetics
المؤلفون: Claire M. Brett, SA Sheardown, Richard A. Castro, Y Shu, Esteban G. Burchard, Kathleen M. Giacomini, L Yue, Ryan P. Owen, Emil T. Lin, RJ Shi, Chaline Brown
المصدر: Clinical Pharmacology & Therapeutics. 83:273-280
مصطلحات موضوعية: Adult, Blood Glucose, Male, medicine.medical_specialty, SLC47A1, Genotype, endocrine system diseases, Cmax, Administration, Oral, Pharmacology, Article, Mice, Gene Frequency, Species Specificity, Pharmacokinetics, Reference Values, Internal medicine, medicine, Animals, Humans, Hypoglycemic Agents, Pharmacology (medical), Allele frequency, Mice, Knockout, Volume of distribution, Polymorphism, Genetic, Organic cation transport proteins, biology, Metformin, Phenotype, Endocrinology, Area Under Curve, biology.protein, Female, Catecholamine Plasma Membrane Transport Proteins, Octamer Transcription Factor-1, medicine.drug
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المؤلفون: Kathleen M. Giacomini, Eugene C. Chen, Claire M. Brett, Sophie L. Stocker, Kari M. Morrissey, Richard A. Castro
المصدر: Clinical pharmacokinetics. 55(4)
مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, Organic cation transport, Adolescent, Organic Cation Transport Proteins, Pharmacology, Kidney, 030226 pharmacology & pharmacy, Article, Cell Line, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Pharmacokinetics, Internal medicine, Medicine, Humans, Hypoglycemic Agents, Pharmacology (medical), Drug Interactions, Nizatidine, Organic cation transport proteins, Cross-Over Studies, biology, business.industry, Kidney metabolism, Middle Aged, In vitro, Metformin, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, HEK293 Cells, biology.protein, Female, business, medicine.drug, Half-Life
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11Interaction of Methotrexate with Organic-Anion Transporting Polypeptide 1A2 and Its Genetic Variants
المؤلفون: Ilaria Badagnani, Esteban G. Burchard, Travis R. Taylor, Michiko Kawamoto, Richard A. Castro, Elaine J. Carlson, Douglas Stryke, Conrad C. Huang, Kathleen M. Giacomini, Claire M. Brett, Susan J. Johns, Thomas E. Ferrin
المصدر: Journal of Pharmacology and Experimental Therapeutics. 318:521-529
مصطلحات موضوعية: musculoskeletal diseases, Molecular Sequence Data, Xenopus, Biological Transport, Active, Organic Anion Transporters, Pharmacology, Biology, Excretion, Xenopus laevis, Extracellular, medicine, Animals, Humans, Amino Acid Sequence, Alleles, Kidney, Genetic Variation, Transporter, Hydrogen-Ion Concentration, Apical membrane, biology.organism_classification, Organic anion-transporting polypeptide, Methotrexate, medicine.anatomical_structure, Toxicity, Oocytes, biology.protein, Folic Acid Antagonists, Molecular Medicine
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المؤلفون: Melanie De La Cruz, Esteban G. Burchard, Leah L. Lagpacan, Kathleen M. Giacomini, Elaine J. Carlson, Douglas Stryke, Travis R. Taylor, Claire M. Brett, Conrad C. Huang, Thomas J. Urban, Thomas E. Ferrin, Lara M. Mangravite, Susan J. Johns, Michiko Kawamoto, Andrew R. Erdman, Richard A. Castro, Wendy Chan
المصدر: American Journal of Physiology-Renal Physiology. 290:F905-F912
مصطلحات موضوعية: Genetics, education.field_of_study, Organic anion transporter 1, biology, Physiology, DNA Mutational Analysis, Population, Genetic Variation, Organic Anion Transporters, Sodium-Independent, Genetics, Population, Pharmaceutical Preparations, Biochemistry, Genetic variation, Ethnicity, biology.protein, Humans, Pharmacokinetics, Allele, education, Allele frequency, Peptide sequence, Functional genomics, Alleles, Loss function
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المؤلفون: Susan J. Johns, Thomas E. Ferrin, Douglas Stryke, Esteban G. Burchard, Michiko Kawamoto, Richard A. Castro, Wendy Chan, Elaine J. Carlson, Conrad C. Huang, Kathleen M. Giacomini, Claire M. Brett, Ilaria Badagnani
المصدر: The Pharmacogenomics Journal. 5:157-165
مصطلحات موضوعية: Models, Molecular, Nonsynonymous substitution, Adenosine, Molecular Sequence Data, Antineoplastic Agents, Biology, Concentrative nucleoside transporter, Xenopus laevis, chemistry.chemical_compound, Ethnicity, Genetics, medicine, Animals, Humans, Coding region, Cation Transport Proteins, Conserved Sequence, Pharmacology, Nucleoside analogue, Mutagenesis, Genetic Variation, Membrane Transport Proteins, Transporter, DNA, Haplotypes, Biochemistry, chemistry, Mutagenesis, Site-Directed, Oocytes, biology.protein, Cladribine, Molecular Medicine, Nucleoside, Vidarabine, medicine.drug
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المؤلفون: Hannah C. Glass, Peter J. Davis, Franklyn Cladis, Claire M. Brett, Andrew T. Costarino, Stephen A. Stayer
المصدر: Glass, HC; Costarino, AT; Stayer, SA; Brett, CM; Cladis, F; & Davis, PJ. (2015). Outcomes for extremely premature infants. Anesthesia and Analgesia, 120(6), 1337-1351. doi: 10.1213/ANE.0000000000000705. UCSF: Retrieved from: http://www.escholarship.org/uc/item/5pw8s5g9
Anesthesia and analgesia, vol 120, iss 6مصطلحات موضوعية: Male, Pediatrics, Time Factors, medicine.medical_treatment, Reproductive health and childbirth, Low Birth Weight and Health of the Newborn, Child Development, Anesthesiology, Risk Factors, Neonatal, Infant Mortality, Medicine, Hospital Mortality, Continuous positive airway pressure, Lung, Pediatric, Gestational age, Patient Discharge, Intensive Care Units, Treatment Outcome, Premature birth, Infant, Extremely Premature, Female, medicine.symptom, medicine.medical_specialty, Clinical Sciences, Gestational Age, Context (language use), Extremely Premature, Article, Sex Factors, Preterm, Intensive Care Units, Neonatal, Intensive care, Humans, Intensive care medicine, Perinatal Mortality, business.industry, Prevention, Intensive Care, Neurosciences, Infant, Newborn, Infant, Perinatal Period - Conditions Originating in Perinatal Period, Newborn, medicine.disease, Infant mortality, Low birth weight, Good Health and Well Being, Anesthesiology and Pain Medicine, Intensive Care, Neonatal, Estimated date of confinement, business
وصف الملف: application/pdf
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المؤلفون: David L Robinowitz, Claire M. Brett
المصدر: Neonatal Anesthesia ISBN: 9781441960405
مصطلحات موضوعية: medicine.medical_specialty, Low birth weight, Obstetrics, business.industry, medicine, Gestation, Congenital malformations, Sudden infant death syndrome, medicine.symptom, business, Infant mortality
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المؤلفون: Kathleen M. Giacomini, Lei Zhang, Claire M. Brett
المصدر: Annual Review of Pharmacology and Toxicology. 38:431-460
مصطلحات موضوعية: Pharmacology, Organic cation transport, Organic cation transport proteins, biology, Chemistry, Toxicology, Intestinal absorption, Intestinal Absorption, Pharmaceutical Preparations, Biochemistry, Pharmacokinetics, Cations, biology.protein, Animals, Humans, Carrier Proteins, Flux (metabolism)
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المؤلفون: Kathleen M. Giacomini, Claire M. Brett, Vikram K. Ramanathan
المصدر: Biochimica et Biophysica Acta (BBA) - Biomembranes. 1330(1):94-102
مصطلحات موضوعية: Taurine, Biophysics, Transport, Choroid plexus, Hypotaurine, In Vitro Techniques, Biology, Polymerase Chain Reaction, Aminobutyric acid, Biochemistry, Epithelium, chemistry.chemical_compound, Cerebrospinal fluid, Nipecotic acid, Animals, γ-Aminobutyric acid, gamma-Aminobutyric Acid, Sodium, Biological Transport, Transporter, Cell Biology, Molecular biology, Kinetics, Guvacine, chemistry, Rabbits
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المصدر: Pharmaceutical Research. 14:406-409
مصطلحات موضوعية: Pharmacology, Taurine, medicine.medical_specialty, Organic Chemistry, Pharmaceutical Science, Biology, eye diseases, Epithelium, chemistry.chemical_compound, medicine.anatomical_structure, Endocrinology, chemistry, Cell culture, Internal medicine, medicine, Molecular Medicine, GABAergic, Cholinergic, Pharmacology (medical), Choroid plexus, sense organs, Taurine transport, Glycine receptor, Biotechnology
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المصدر: Pharmaceutical Research. 13:952-956
مصطلحات موضوعية: Pharmacology, Pathology, medicine.medical_specialty, Lagomorpha, Organic Chemistry, Pharmacology toxicology, Pharmaceutical Science, Rabbit (nuclear engineering), Biology, Membrane transport, biology.organism_classification, Epithelium, Cell biology, Investigation methods, medicine.anatomical_structure, Cell culture, medicine, Molecular Medicine, Pharmacology (medical), Choroid plexus, Biotechnology
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المؤلفون: Youcai Zhang, Chaline Brown, Sophie L. Stocker, Anh Nguyet Nguyen, Richard A. Castro, Claire M. Brett, Cheryl D. Cropp, Ji Ha Choi, Yong Huang, Harunobu Tahara, Radojka M. Savic, Sook Wah Yee, Diment Singh, Kathleen M. Giacomini
المصدر: Journal of pharmaceutical sciences, vol 102, iss 9
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, pharmacogenomic, Kidney Disease, Cefotaxime, Organic anion transporter 1, Adolescent, cefotaxime, organic anion transporter, Organic Anion Transporters, Pharmaceutical Science, Pharmacology, Organic Anion Transporters, Sodium-Independent, OAT3, Kidney, Article, Young Adult, Genetic, Pharmacokinetics, Asian People, Gene Frequency, Clinical Research, In vivo, Internal medicine, medicine, Humans, Pharmacology & Pharmacy, Polymorphism, Allele frequency, Sodium-Independent, Polymorphism, Genetic, biology, renal clearance, Kidney metabolism, Pharmacology and Pharmaceutical Sciences, tubular secretion, Anti-Bacterial Agents, medicine.anatomical_structure, Endocrinology, HEK293 Cells, Renal physiology, biology.protein, Female, polymorphisms, pharmacokinetics, medicine.drug
وصف الملف: application/pdf