المؤلفون: Murray, Meghan H., Valfort, Aurore Cecile, Koelblen, Thomas, Ronin, Céline, Ciesielski, Fabrice, Chatterjee, Arindam, Veerakanellore, Giri Babu, Elgendy, Bahaa, Walker, John K., Hegazy, Lamees, Burris, Thomas P.

المساهمون: U.S. Department of Defense, U.S. Department of Health & Human Services | National Institutes of Health

المصدر: Nature Communications ; volume 13, issue 1 ; ISSN 2041-1723

الاتاحة: http://dx.doi.org/10.1038/s41467-022-34892-4
https://www.nature.com/articles/s41467-022-34892-4.pdf
https://www.nature.com/articles/s41467-022-34892-4

المؤلفون: Dickie, Emily A, Ronin, Céline, Sá, Mónica, Ciesielski, Fabrice, Trouche, Nathalie, Tavares, Joana, Santarem, Nuno, Major, Louise L, Pemberton, Iain K, MacDougall, Jane, Smith, Terry K, Cordeiro-da-Silva, Anabela, Ciapetti, Paola

المصدر: Dickie , E A , Ronin , C , Sá , M , Ciesielski , F , Trouche , N , Tavares , J , Santarem , N , Major , L L , Pemberton , I K , MacDougall , J , Smith , T K , Cordeiro-da-Silva , A & Ciapetti , P 2021 , ' Towards chemical validation of Leishmania infantum ribose 5-phosphate isomerase as a drug target ' , Antimicrobial Agents and Chemotherapy , vol. Early . https://doi.org/10.1128/AAC.01892-20

مصطلحات موضوعية: Neglected tropical diseases, Leishmania infantum, Leishmaniasis, Ribose 5-phosphate isomerase, Inhibitor, Screening, Thermal shift, Anti-parasitic, Protein crystal structure

وصف الملف: application/pdf

الاتاحة: https://risweb.st-andrews.ac.uk/portal/en/researchoutput/towards-chemical-validation-of-leishmania-infantum-ribose-5phosphate-isomerase-as-a-drug-target(0d85a37c-90b8-4238-8024-7861ae06e30f).html
https://doi.org/10.1128/AAC.01892-20
https://research-repository.st-andrews.ac.uk/bitstream/10023/24164/1/Dickie_2021_AAC_Towards_chemical_AAM.pdf

المؤلفون: Gaspar, Luís, Coron, Ross P., Kongthoo Lin, Paul, Costa, David M., Perez-Cabezas, Begoña, Tavares, Joana, Roura-Ferrer, Meritxell, Ramos, Isbaal, Ronin, Céline, Major, Louise L., Ciesielski, Fabrice, Pemberton, Iain K., MacDougall, Jane, Ciapetti, Paola, Smith, Terry K., Cordeiro-da-Silva, Anabela

المساهمون: European Commission, University of St Andrews. School of Biology, University of St Andrews. Biomedical Sciences Research Complex

مصطلحات موضوعية: QH301 Biology, RM Therapeutics. Pharmacology, NDAS, SDG 3 - Good Health and Well-being, QH301, RM

وصف الملف: application/pdf

Relation: PLoS Neglected Tropical Diseases; Gaspar , L , Coron , R P , Kongthoo Lin , P , Costa , D M , Perez-Cabezas , B , Tavares , J , Roura-Ferrer , M , Ramos , I , Ronin , C , Major , L L , Ciesielski , F , Pemberton , I K , MacDougall , J , Ciapetti , P , Smith , T K & Cordeiro-da-Silva , A 2018 , ' Inhibitors of Trypanosoma cruzi Sir2 related protein 1 as potential drugs against Chagas disease ' , PLoS Neglected Tropical Diseases , vol. 12 , no. 1 , e0006180 . https://doi.org/10.1371/journal.pntd.0006180; PURE: 252276932; PURE UUID: 8c03d29e-8a7d-4a3b-bce1-b8dd5f487bf0; crossref: 10.1371/journal.pntd.0006180; Scopus: 85041585443; ORCID: /0000-0001-5287-4488/work/51010274; WOS: 000424022700042; http://hdl.handle.net/10023/12710; https://doi.org/10.1371/journal.pntd.0006180

الاتاحة: http://hdl.handle.net/10023/12710
https://doi.org/10.1371/journal.pntd.0006180

المؤلفون: Ronin, Céline, Costa, David Mendes, Tavares, Joana, Faria, Joana, Ciesielski, Fabrice, Ciapetti, Paola, Smith, Terry K., MacDougall, Jane, Cordeiro-da-Silva, Anabela, Pemberton, Iain K.

المصدر: Ronin , C , Costa , D M , Tavares , J , Faria , J , Ciesielski , F , Ciapetti , P , Smith , T K , MacDougall , J , Cordeiro-da-Silva , A & Pemberton , I K 2018 , ' The crystal structure of the Leishmania infantum Silent Information Regulator 2 related protein 1 : implications to protein function and drug design ' , PLoS One , vol. 13 , no. 3 , e0193602 . https://doi.org/10.1371/journal.pone.0193602

وصف الملف: application/pdf

الاتاحة: https://risweb.st-andrews.ac.uk/portal/en/researchoutput/the-crystal-structure-of-the-leishmania-infantum-silent-information-regulator-2-related-protein-1(311d73e1-fcd9-4bd3-b15d-ab159f0a5ae8).html
https://doi.org/10.1371/journal.pone.0193602
https://research-repository.st-andrews.ac.uk/bitstream/10023/13057/1/Ronin_2018_PLoSONE_Leishmaniainfantum_CC.pdf
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0193602#sec028

المؤلفون: Ronan, Celin, Mendes Costa, David, Tavares, Joana, Correia Faria, Joana Raquel, Ciesielski, Fabrice, Ciapetti, Paola, Smith, Terry K., MacDougall, Jane, Cordeiro-da-Silva, Anabela, Pemberton, Ian K

وصف الملف: text

Relation: https://eprints.whiterose.ac.uk/182403/1/file.pdf; Ronan, Celin, Mendes Costa, David, Tavares, Joana et al. (7 more authors) (2018) The crystal structure of the Leishmania infantum Silent Information Regulator 2 related protein 1: implications to protein function and drug design. PLoS ONE. ISSN 1932-6203

الاتاحة: https://eprints.whiterose.ac.uk/182403/
https://eprints.whiterose.ac.uk/182403/1/file.pdf
https://doi.org/10.2210/pdb5OL0/pdb

المؤلفون: Huet, Tiphaine, Laverny, Gilles, Ciesielski, Fabrice, Molnár, Ferdinand, Ramamoorthy, Thanuja Gali, Belorusova, Anna Y., Antony, Pierre, Potier, Noelle, Metzger, Daniel, Moras, Dino, Rochel, Natacha

المصدر: Cell Reports ; volume 10, issue 4, page 516-526 ; ISSN 2211-1247

الاتاحة: http://dx.doi.org/10.1016/j.celrep.2014.12.045
https://api.elsevier.com/content/article/PII:S2211124714010985?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S2211124714010985?httpAccept=text/xml

المؤلفون: Radaeva, Mariia, Li, Huifang, LeBlanc, Eric, Dalal, Kush, Ban, Fuqiang, Ciesielski, Fabrice, Chow, Bonny, Morin, Helene, Awrey, Shannon, Singh, Kriti, Rennie, Paul S., Lallous, Nada, Cherkasov, Artem

المصدر: Cells (2073-4409); Sep2022, Vol. 11 Issue 18, pN.PAG-N.PAG, 18p

مصطلحات موضوعية: ANDROGEN receptors, CROSS reactions (Immunology), LIGAND binding (Biochemistry), PROSTATE cancer patients, BINDING sites, MORPHOLINE

المؤلفون: Paris, Mathilde, Escriva, Hector, Schubert, Michael, Brunet, Frédéric, Brtko, Julius, Ciesielski, Fabrice, Roecklin, Dominique, Vivat-Hannah, Valérie, Jamin, Emilien L., Cravedi, Jean-Pierre, Scanlan, Thomas S., Renaud, Jean-Paul, Holland, Nicholas D., Laudet, Vincent

المصدر: Current Biology ; volume 18, issue 11, page 825-830 ; ISSN 0960-9822

الاتاحة: http://dx.doi.org/10.1016/j.cub.2008.04.078
https://api.elsevier.com/content/article/PII:S0960982208006623?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0960982208006623?httpAccept=text/plain

المؤلفون: Hourai, Shinji, Rodrigues, Luis Cezar, Antony, Pierre, Reina-San-Martin, Bernardo, Ciesielski, Fabrice, Magnier, Benjamin Claude, Schoonjans, Kristina, Mouriño, Antonio, Rochel, Natacha, Moras, Dino

المصدر: Chemistry & Biology ; volume 15, issue 4, page 383-392 ; ISSN 1074-5521

الاتاحة: http://dx.doi.org/10.1016/j.chembiol.2008.03.016
https://api.elsevier.com/content/article/PII:S1074552108001270?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1074552108001270?httpAccept=text/plain

المؤلفون: Atmanene, Cédric, Ronin, Céline, Téletchéa, Stéphane, Gautier, François-Moana, Djedaini-Pilard, Florence, Ciesielski, Fabrice, Vivat, Valérie, Grandjean, Cyrille

المساهمون: Laboratoire de Spectrométrie de Masse BioOrganique Strasbourg (LSMBO), Département Sciences Analytiques et Interactions Ioniques et Biomoléculaires (DSA-IPHC), Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Institut Pluridisciplinaire Hubert Curien (IPHC), Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS), Physiopathologie des Adaptations Nutritionnelles (PhAN), Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Laboratoire de Glycochimie, des Antimicrobiens et des Agro-ressources - UMR CNRS 7378 (LG2A), Université de Picardie Jules Verne (UPJV)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Institut de génétique et biologie moléculaire et cellulaire (IGBMC), Université Louis Pasteur - Strasbourg I-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)

المصدر: ISSN: 0006-291X.

مصطلحات موضوعية: [CHIM]Chemical Sciences, [CHIM.ORGA]Chemical Sciences/Organic chemistry, [CHIM.CRIS]Chemical Sciences/Cristallography, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, [CHIM.THER]Chemical Sciences/Medicinal Chemistry

الاتاحة: https://hal.science/hal-02197010
https://doi.org/10.1016/j.bbrc.2017.05.150

المؤلفون: Ouvry, Gilles, Bouix-Peter, Claire, Ciesielski, Fabrice, Chantalat, Laurent, Christin, Olivier, Comino, Catherine, Duvert, Denis, Feret, Christophe, Harris, Craig S., Lamy, Laurent, Luzy, Anne-Pascale, Musicki, Branislav, Orfila, Danielle, Pascau, Jonathan, Parnet, Véronique, Perrin, Agnès, Pierre, Romain, Polge, Gaëlle, Raffin, Catherine, Rival, Yves, Taquet, Nathalie, Thoreau, Etienne, Hennequin, Laurent F.

المصدر: Bioorganic & Medicinal Chemistry Letters ; volume 26, issue 23, page 5802-5808 ; ISSN 0960-894X

الاتاحة: http://dx.doi.org/10.1016/j.bmcl.2016.10.023
https://api.elsevier.com/content/article/PII:S0960894X16310514?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0960894X16310514?httpAccept=text/plain

المؤلفون: Menet, Christel J., Fletcher, Stephen R, Van Lommen, Guy, Geney, Raphael, Blanc, Javier, Smits, Koen, Jouannigot, Nolwenn, Deprez, Pierre, van der Aar, Ellen M., Clement-Lacroix, Philippe, Lepescheux, Liên, Galien, René, Vayssiere, Béatrice, Nelles, Luc, Christophe, Thierry, Brys, Reginald, Uhring, Muriel, Ciesielski, Fabrice, Van Rompaey, Luc

المساهمون: GlaxoSmithKline

المصدر: Journal of Medicinal Chemistry ; volume 57, issue 22, page 9323-9342 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/jm501262q
https://pubs.acs.org/doi/pdf/10.1021/jm501262q

المؤلفون: Ciesielski, Fabrice, Sato, Yoshiteru, Chebaro, Yassmine, Moras, Dino, Dejaegere, Annick, Rochel, Natacha

المصدر: Journal of Medicinal Chemistry ; volume 55, issue 19, page 8440-8449 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/jm300858s
https://pubs.acs.org/doi/pdf/10.1021/jm300858s

المؤلفون: Ronin, Céline, Costa, David Mendes, Tavares, Joana, Faria, Joana, Ciesielski, Fabrice, Ciapetti, Paola, Smith, Terry K., MacDougall, Jane, Cordeiro-da-Silva, Anabela, Pemberton, Iain K.

المصدر: PLoS ONE; 3/15/2018, Vol. 13 Issue 3, p1-26, 26p

مصطلحات موضوعية: LEISHMANIA infantum, SIRTUINS, DRUG design, KINETOPLASTIDA, AMINO acids

المؤلفون: Rochel, Natacha, Ciesielski, Fabrice, Godet, Julien, Moman, Edelmiro, Roessle, Manfred, Peluso-Iltis, Carole, Moulin, Martine, Haertlein, Michael, Callow, Phil, Mély, Yves, Svergun, Dmitri I, Moras, Dino

المصدر: Nature Structural & Molecular Biology ; volume 18, issue 5, page 564-570 ; ISSN 1545-9993 1545-9985

الاتاحة: http://dx.doi.org/10.1038/nsmb.2054
http://www.nature.com/articles/nsmb.2054.pdf
http://www.nature.com/articles/nsmb.2054

المؤلفون: Ciesielski, Fabrice, Rochel, Natacha, Moras, Dino

المساهمون: Institut de génétique et biologie moléculaire et cellulaire (IGBMC), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Louis Pasteur - Strasbourg I

المصدر: ISSN: 0960-0760 ; Journal of Steroid Biochemistry and Molecular Biology ; https://hal.archives-ouvertes.fr/hal-00190967 ; Journal of Steroid Biochemistry and Molecular Biology, Elsevier, 2007, 103 (3-5), pp.235-42. ⟨10.1016/j.jsbmb.2006.12.003⟩.

مصطلحات موضوعية: MESH: Adaptation, Biological, MESH: Animals, MESH: Protein Binding, MESH: Protein Structure, Tertiary, MESH: Rats, MESH: Receptors, Calcitriol, MESH: Zebrafish, MESH: Binding Sites, MESH: Calcitriol, MESH: Cell Nucleus, MESH: Crystallography, X-Ray, MESH: Humans, MESH: Ligands, MESH: Models, Molecular, MESH: Mutation, [SDV.BBM.BM]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Molecular biology

Relation: info:eu-repo/semantics/altIdentifier/pmid/17218092; hal-00190967; https://hal.archives-ouvertes.fr/hal-00190967; PUBMED: 17218092

الاتاحة: https://hal.archives-ouvertes.fr/hal-00190967
https://doi.org/10.1016/j.jsbmb.2006.12.003

المؤلفون: Ciesielski, Fabrice, Rochel, Natacha, Mitschler, André, Kouzmenko, Alexander, Moras, Dino

المساهمون: Institut de génétique et biologie moléculaire et cellulaire (IGBMC), Université Louis Pasteur - Strasbourg I-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), The University of Tokyo (UTokyo)

المصدر: ISSN: 0960-0760 ; Journal of Steroid Biochemistry and Molecular Biology ; https://hal.science/hal-04138418 ; Journal of Steroid Biochemistry and Molecular Biology, 2004, 89-90 (1-5), pp.55-59. ⟨10.1016/j.jsbmb.2004.03.109⟩.

مصطلحات موضوعية: [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology

Relation: info:eu-repo/semantics/altIdentifier/pmid/15225747; hal-04138418; https://hal.science/hal-04138418; PUBMED: 15225747

الاتاحة: https://hal.science/hal-04138418
https://doi.org/10.1016/j.jsbmb.2004.03.109

المؤلفون: Menet, Christel J., Fletcher, Stephen R., Van Lommen, Guy, Geney, Raphael, Blanc, Javier, Smits, Koen, Jouannigot, Nolwenn, Deprez, Pierre, van der Aar, Ellen M., Clement-Lacroix, Philippe, Lepescheux, Liên, Galien, René, Vayssiere, Béatrice, Nelles, Luc, Christophe, Thierry, Brys, Reginald, Uhring, Muriel, Ciesielski, Fabrice, Van Rompaey, Luc

المصدر: Journal of Medicinal Chemistry; Nov2014, Vol. 57 Issue 22, p9323-9342, 20p

المؤلفون: Ciesielski, Fabrice, Sato, Yoshiteru, Chebaro, Yassmine, Moras, Dino, Dejaegere, Annick, Rochel, Natacha

المصدر: Journal of Medicinal Chemistry; Oct2012, Vol. 55 Issue 19, p8440-8449, 10p

المؤلفون: Dickie, Emily A., Ronin, Céline, Sá, Mónica, Ciesielski, Fabrice, Trouche, Nathalie, Tavares, Joana, Santarem, Nuno, Major, Louise L., Pemberton, Iain K., MacDougall, Jane, Smith, Terry K., Cordeiro-da-Silva, Anabela, Ciapetti, Paola

المصدر: Antimicrobial Agents and Chemotherapy; May 2021, Vol. 1 Issue: 1