نتائج البحث - "Ciceri, Filippo"

1

Academic Journal

Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies

المصدر: Nicosia , L , Spencer , G J , Brooks , N , Amaral , F M R , Basma , N J , Chadwick , J A , Revell , B , Wingelhofer , B , Maiques-Diaz , A , Sinclair , O , Camera , F , Ciceri , F , Wiseman , D H , Pegg , N , West , W , Knurowski , T , Frese , K , Clegg , K , Campbell , V L , Cavet , J , Copland , M , Searle , E & Somervaille , T C ....

مصطلحات موضوعية: Humans, Nuclear Proteins, Cell Line, Tumor, Transcription Factors, Protein Domains, Hematologic Neoplasms/drug therapy, E1A-Associated p300 Protein

Relation: https://research.manchester.ac.uk/en/publications/c2958e1e-a6ee-4b2c-b38d-b8bffab3e0d8

الاتاحة: https://research.manchester.ac.uk/en/publications/c2958e1e-a6ee-4b2c-b38d-b8bffab3e0d8
https://doi.org/10.1016/j.ccell.2023.11.001
http://www.scopus.com/inward/record.url?scp=85179030914&partnerID=8YFLogxK
https://www.mendeley.com/catalogue/7037708a-3807-3d5f-9fe6-d1ed9230fea5/

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2

Academic Journal

Chemoprobe-based assays of histone lysine demethylase 1A target occupation enable in vivo pharmacokinetics and pharmacodynamics studies of KDM1A inhibitors

المؤلفون: Mascaró, Cristina, Ortega, Alberto, Carceller, Elena, Ruiz Rodriguez, Raquel, Ciceri, Filippo, Lunardi, Serena, Yu, Li, Hilbert, Manuel, Maes, Tamara

المساهمون: Roche

المصدر: Journal of Biological Chemistry ; volume 294, issue 20, page 8311-8322 ; ISSN 0021-9258

الاتاحة: http://dx.doi.org/10.1074/jbc.ra118.006980
https://api.elsevier.com/content/article/PII:S0021925820363833?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0021925820363833?httpAccept=text/plain
https://syndication.highwire.org/content/doi/10.1074/jbc.RA118.006980

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3

Conference

Therapeutic targeting of EP300/CBP by bromodomain inhibition in acute myeloid leukemia

المساهمون: Cancer Research UK Manchester Institute, The University of Manchester, Manchester

Relation: https://dx.doi.org/10.1182/blood-2022-166260; Nicosia L, Spencer GJ, Brooks N, Amaral F, Basma N, Chadwick J, et al. Therapeutic Targeting of EP300/CBP By Bromodomain Inhibition in Acute Myeloid Leukemia. Blood. 2022 Nov;140:8774-5. PubMed PMID: WOS:000893230301382.; http://hdl.handle.net/10541/626203; Blood

الاتاحة: http://hdl.handle.net/10541/626203
https://doi.org/10.1182/blood-2022-166260

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4

Academic Journal

Enhancer activation by pharmacologic displacement of LSD1 from GFI1 induces differentiation in acute myeloid leukemia

المؤلفون: Maiques-Diaz, Alba, Spencer, Gary, Lynch, James, Ciceri, Filippo, Williams, Emma, Amaral, Fabio, Wiseman, Daniel, Li, Yaoyong, Sahoo, Sudhakar, Hitchin, James, Mould, Daniel, Fairweather, Emma, Waszkowycz, Bohdan, Jordan, Allan, Smith, Duncan, Somervaille, Timothy

المصدر: Maiques-Diaz , A , Spencer , G , Lynch , J , Ciceri , F , Williams , E , Amaral , F , Wiseman , D , Li , Y , Sahoo , S , Hitchin , J , Mould , D , Fairweather , E , Waszkowycz , B , Jordan , A , Smith , D & Somervaille , T 2018 , ' Enhancer activation by pharmacologic displacement of LSD1 from GFI1 induces differentiation in acute myeloid leukemia ' , Cell Reports , vol. 22 , no. 13 , pp. 3641-3659 . https://doi.org/10.1016/j.celrep.2018.03.012

مصطلحات موضوعية: GFI1, LSD1, MLL, acetylation, acute myeloid leukemia, methylation, ResearchInstitutes_Networks_Beacons/mcrc, name=Manchester Cancer Research Centre

Relation: https://research.manchester.ac.uk/en/publications/d9eb8656-9c8c-4d3c-9ffb-ea28e5671b50

الاتاحة: https://research.manchester.ac.uk/en/publications/d9eb8656-9c8c-4d3c-9ffb-ea28e5671b50
https://doi.org/10.1016/j.celrep.2018.03.012

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5

Academic Journal

Oral administration of the LSD1 inhibitor ORY-3001 increases fetal hemoglobin in sickle cell mice and baboons

المؤلفون: Rivers, Angela, Vaitkus, Kestis, Jagadeeswaran, Ramasamy, Ruiz, Maria Armila, Ibanez, Vinzon, Ciceri, Filippo, Cavalcanti, Fernando, Molokie, Robert E., Saunthararajah, Yogen, Engel, James Douglas, DeSimone, Joseph, Lavelle, Donald

المساهمون: National Institutes of Health

المصدر: Experimental Hematology ; volume 67, page 60-64.e2 ; ISSN 0301-472X

الاتاحة: http://dx.doi.org/10.1016/j.exphem.2018.08.003
https://api.elsevier.com/content/article/PII:S0301472X18307501?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0301472X18307501?httpAccept=text/plain

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6

Academic Journal

ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia

المساهمون: Spanish Ministry of Investigation, Development and Innovation, EUROSTARS program, Cancer Research UK, Bloodwise Clinical Training

المصدر: Cancer Cell ; volume 33, issue 3, page 495-511.e12 ; ISSN 1535-6108

الاتاحة: http://dx.doi.org/10.1016/j.ccell.2018.02.002
https://api.elsevier.com/content/article/PII:S1535610818300230?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1535610818300230?httpAccept=text/plain

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7

Academic Journal

The Histone Demethylase KDM1A Sustains the Oncogenic Potential of MLL-AF9 Leukemia Stem Cells

المؤلفون: Harris, William J., Huang, Xu, Lynch, James T., Spencer, Gary J., Hitchin, James R., Li, Yaoyong, Ciceri, Filippo, Blaser, Julian G., Greystoke, Brigit F., Jordan, Allan M., Miller, Crispin J., Ogilvie, Donald J., Somervaille, Tim C.P.

المصدر: Cancer Cell ; volume 21, issue 4, page 473-487 ; ISSN 1535-6108

الاتاحة: http://dx.doi.org/10.1016/j.ccr.2012.03.014
https://api.elsevier.com/content/article/PII:S1535610812001237?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S1535610812001237?httpAccept=text/plain

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8

Conference

Content-Based approaches for Cold-Start Job Recommendations

المؤلفون: Bianchi, Mattia, Cesaro, Federico, Ciceri, Filippo, Dagrada, Mattia, Gasparin, Alberto, Grattarola, Daniele, Inajjar, Ilyas, Metelli, Alberto Maria, Cella, Leonardo

المصدر: Proceedings of the Recommender Systems Challenge 2017

الاتاحة: http://dx.doi.org/10.1145/3124791.3124793
https://dl.acm.org/doi/pdf/10.1145/3124791.3124793

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9

Academic Journal

Understanding Epigenetic Alterations in Alzheimer's and Parkinson's Disease: Towards Targeted Biomarkers and Therapies

المؤلفون: Ciceri, Filippo, Rotllant, David, Maes, Tamara

المصدر: Current Pharmaceutical Design ; volume 23, issue 5, page 839-857 ; ISSN 1381-6128

الاتاحة: http://dx.doi.org/10.2174/1381612823666170124121140
http://eurekaselect.com/article/download/149464

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10

Conference

Pharmacological Inhibitors of LSD1 Promote Differentiation of Myeloid Leukemia Cells through a Mechanism Independent of Histone Demethylation

المؤلفون: Lynch, James T., Spencer, Gary J., Harris, William J., Maiques-Díaz, Alba, Ciceri, Filippo, Huang, Xu, Somervaille, Tim C.P.

Relation: Lynch, J. T., Spencer, G. J., Harris, W. J., Maiques-Díaz, A., Ciceri, F., Huang, X. and Somervaille, T. C.P. (2014) Pharmacological Inhibitors of LSD1 Promote Differentiation of Myeloid Leukemia Cells through a Mechanism Independent of Histone Demethylation. 56th ASH Annual Meeting, San Francisco, CA, USA, 6-9 Dec 2014.

الاتاحة: http://eprints.gla.ac.uk/191832/

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11

Academic Journal

KDM1 histone lysine demethylases as targets for treatments of oncological and neurodegenerative disease.

المؤلفون: Maes, Tamara, Mascaró, Cristina, Ortega, Alberto, Lunardi, Serena, Ciceri, Filippo, Somervaille, Tim C P, Buesa, Carlos

المصدر: Maes , T , Mascaró , C , Ortega , A , Lunardi , S , Ciceri , F , Somervaille , T C P & Buesa , C 2015 , ' KDM1 histone lysine demethylases as targets for treatments of oncological and neurodegenerative disease. ' , Epigenomics , vol. 7 , no. 4 . https://doi.org/10.2217/epi.15.9

مصطلحات موضوعية: Alzheimer's disease, GSK2879552, Huntington's disease, ORY-1001, ORY-2001, SCLC, acute myeloid leukemia, histone lysine demethylases (KDMs), oncology, ResearchInstitutes_Networks_Beacons/mcrc, Manchester Cancer Research Centre