المؤلفون: Marthe M. Vandeputte, Grant C. Glatfelter, Donna Walther, Nathan K. Layle, Danielle M. St. Germaine, István Ujváry, Donna M. Iula, Michael H. Baumann, Christophe P. Stove

المصدر: Pharmacological Research, Vol 210, Iss , Pp 107503- (2024)

مصطلحات موضوعية: Nitazene, New synthetic opioids, In vitro and in vivo pharmacology, Structure-activity relationships, 2-Benzylbenzimidazoles, µ-Opioid receptor, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1043661824004481; https://doaj.org/toc/1096-1186

URL الوصول: https://doaj.org/article/1e6ec420012c427cb9ccc61ca32e7ede

المؤلفون: Liam M. De Vrieze, Christophe P. Stove, Marthe M. Vandeputte

المصدر: Harm Reduction Journal, Vol 21, Iss 1, Pp 1-13 (2024)

مصطلحات موضوعية: New synthetic opioids (NSO), 2-Benzylbenzimidazole ‘nitazene’ opioids, Harm reduction, Drug checking, Immunoassay test strips, Public aspects of medicine, RA1-1270

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1477-7517

URL الوصول: https://doaj.org/article/54320f21a26f423fa693a22c41436cfa

المؤلفون: Axelle Timmerman, Margot Balcaen, Vera Coopman, Maarten Degreef, Eline Pottie, Christophe P. Stove

المصدر: Harm Reduction Journal, Vol 21, Iss 1, Pp 1-11 (2024)

مصطلحات موضوعية: Untargeted screening, CB1 cannabinoid receptor bioassay, Adulterated cannabis, Synthetic cannabinoid receptor agonists (SCRAs), New psychoactive substances (NPS), Harm reduction, Public aspects of medicine, RA1-1270

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1477-7517

URL الوصول: https://doaj.org/article/18b9720cec984ed6b441b06536311dbd

المؤلفون: Philipp Spatz, Sophie A M Steinmüller, Anna Tutov, Eleonora Poeta, Axelle Morilleau, Allison Carles, Marie H Deventer, Julian Hofmann, Christophe P Stove, Barbara Monti, Tangui Maurice, Michael Decker

المساهمون: Philipp Spatz, Sophie A M Steinmüller , Anna Tutov , Eleonora Poeta , Axelle Morilleau , Allison Carles , Marie H Deventer , Julian Hofmann , Christophe P Stove , Barbara Monti , Tangui Maurice , Michael Decker

مصطلحات موضوعية: Cannabinoid Receptor 2. Butyrylcholinesterase, Neuroprotection, Alzheimer’s Disease

وصف الملف: ELETTRONICO

Relation: info:eu-repo/semantics/altIdentifier/pmid/37127287; volume:66; issue:9; firstpage:6414; lastpage:6435; numberofpages:22; journal:JOURNAL OF MEDICINAL CHEMISTRY; https://hdl.handle.net/11585/925248; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85156227895

الاتاحة: https://hdl.handle.net/11585/925248
https://doi.org/10.1021/acs.jmedchem.3c00541
https://pubs.acs.org/doi/10.1021/acs.jmedchem.3c00541

المؤلفون: Liesl K. Janssens, Laurie De Wilde, Peter Van Eenoo, Christophe P. Stove

مصطلحات موضوعية: Biochemistry, Medicine, Genetics, Biotechnology, Ecology, Developmental Biology, Cancer, Computational Biology, Mathematical Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, vitro bioassay hypoxia, improved pharmacological characterization, doping agency ’, reference compound roxadustat, strong matrix effects, previously developed cell, matching urine samples, hif stabilizing activity, detecting biological activity, doping samples, matrix effects, doping control, stable cell, world anti, unknown substance, rapid pace, prohibited list, practical context, pharmacologically characterizing, pending optimization

Relation: https://figshare.com/articles/journal_contribution/Untargeted_Detection_of_HIF_Stabilizers_in_Doping_Samples_Activity-Based_Screening_with_a_Stable_In_Vitro_Bioassay/24879067

الاتاحة: https://doi.org/10.1021/acs.analchem.3c03816.s001
https://figshare.com/articles/journal_contribution/Untargeted_Detection_of_HIF_Stabilizers_in_Doping_Samples_Activity-Based_Screening_with_a_Stable_In_Vitro_Bioassay/24879067

المؤلفون: René A. J. Crans, Elise Wouters, Marta Valle-León, Jaume Taura, Caio M. Massari, Víctor Fernández-Dueñas, Christophe P. Stove, Francisco Ciruela

المصدر: Frontiers in Pharmacology, Vol 13 (2022)

مصطلحات موضوعية: D2R, M1R, sumanirole, VU0255035, striatum, Parkinson’s disease, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2022.1075433/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/137c8a0904b543838a2edd3f05da1ad5

المؤلفون: Nick Verougstraete, Veronique Stove, Alain G. Verstraete, Christophe P. Stove

المصدر: Frontiers in Oncology, Vol 12 (2022)

مصطلحات موضوعية: tyrosine kinase inhibitors, therapeutic drug monitoring, microsampling, dried blood microsamples, oncology drugs, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.821807/full; https://doaj.org/toc/2234-943X

URL الوصول: https://doaj.org/article/fa338079719a4d6e98946962b11dddf8

المؤلفون: Liesl K. Janssens (11597498), Adam Ametovski (6308633), Eric Sparkes (9525663), Rochelle Boyd (4350694), Felcia Lai (11153268), Callan J. Maloney (12399842), Dane Rhook (14277552), Roy R. Gerona (1890775), Matthew Connolly (13269867), Huiling Liu (481477), David E. Hibbs (183890), Elizabeth A. Cairns (10688692), Samuel D. Banister (281873), Christophe P. Stove (1235217)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Molecular Biology, Cancer, Chemical Sciences not elsewhere classified, optimal steric contribution, optimal chain length, illicit drug market, different signaling event, comparing derived potency, allow adequate interpretation, new psychoactive substances, differential compound characterization, altered compound characterization, three assay formats, comprehensive pharmacological characterization, cyclohexylmethyl tail ), 1 , assay formats, comprehensive characterization, cyclohexylmethyl tails, via <, pendant tail, hydrophobic tail, whereas ranges, terminally truncated, systematic library, structural evolution, rapid pace

Relation: https://figshare.com/articles/journal_contribution/Comprehensive_Characterization_of_a_Systematic_Library_of_Alkyl_and_Alicyclic_Synthetic_Cannabinoids_Related_to_CUMYL-PICA_CUMYL-BUTICA_CUMYL-CBMICA_and_CUMYL-PINACA/21749442

الاتاحة: https://doi.org/10.1021/acschemneuro.2c00408.s001

المؤلفون: Bart Van Puyvelde (7325378), Katleen Van Uytfanghe (8045234), Laurence Van Oudenhove (235865), Ralf Gabriels (8903903), Tessa Van Royen (14242055), Arne Matthys (14242058), Morteza Razavi (375073), Richard Yip (2198194), Terry Pearson (59741), Nicolas Drouin (2626048), Jan Claereboudt (10740529), Dominic Foley (14236946), Robert Wardle (14236955), Kevin Wyndham (2052277), Thomas Hankemeier (135670), Donald Jones (1357), Xavier Saelens (28372), Geert Martens (14242061), Christophe P. Stove (1235217), Dieter Deforce (20882), Lennart Martens (14237), Johannes P.C. Vissers (7241525), N. Leigh Anderson (10740532), Maarten Dhaenens (466100)

مصطلحات موضوعية: Biochemistry, Medicine, Biotechnology, Cancer, Infectious Diseases, Computational Biology, Biological Sciences not elsewhere classified, targeting different biomolecules, strong positive correlation, mass spectrometric measurement, fold improvement compared, enrich proteotypic peptides, early warning system, automatable sample preparation, adding siscapa technology, 30 – 31, many different pathogens, digested patient samples, qpcr detection beyond, 2 , pooled samples, pathogens within, 2 nucleocapsid, direct detection, b detection, quantification cycle, propose targets, live virus, large numbers, independent assay

Relation: https://figshare.com/articles/journal_contribution/Cov_sup_2_sup_MS_An_Automated_and_Quantitative_Matrix-Independent_Assay_for_Mass_Spectrometric_Measurement_of_SARS-CoV_2_Nucleocapsid_Protein/21706043

الاتاحة: https://doi.org/10.1021/acs.analchem.2c01610.s001

المؤلفون: Eline Pottie, Jolien Storme, Christophe P. Stove

المصدر: International Journal of Molecular Sciences; Volume 23; Issue 7; Pages: 3460

مصطلحات موضوعية: P2Y 2 receptor, β-arrestin2, β-arrestin1, nanoluciferase, live-cell reporter assay

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Endocrinology and Metabolism; https://dx.doi.org/10.3390/ijms23073460

الاتاحة: https://doi.org/10.3390/ijms23073460

المؤلفون: Liesl K. Janssens (11597498), Christophe P. Stove (1235217)

مصطلحات موضوعية: Biophysics, Biochemistry, Genetics, Molecular Biology, Biotechnology, Inorganic Chemistry, Plant Biology, Computational Biology, Chemical Sciences not elsewhere classified, utilizing functional complementation, two live cell, proteasome inhibitor mg, og mimetic dimethyloxalylglycine, hek293t transfection protocol, gene reporter assays, downstream transcriptional activity, well format, upstream event, principle relies, oxygen sensor, optimal configuration, novel approach, inducible factor, indicating concentration, including roxadustat, fusion proteins, efficacy (<, e <, dependent effects, demonstrated using

Relation: https://figshare.com/articles/journal_contribution/Sensing_an_Oxygen_Sensor_Development_and_Application_of_Activity-Based_Assays_Directly_Monitoring_HIF_Heterodimerization/16862345

الاتاحة: https://doi.org/10.1021/acs.analchem.1c02923.s001

المؤلفون: Eline Pottie (8045231), Olga V. Kupriyanova (10197619), Vadim A. Shevyrin (10197622), Christophe P. Stove (1235217)

مصطلحات موضوعية: Biochemistry, Cell Biology, Biotechnology, Mental Health, Computational Biology, Physical Sciences not elsewhere classified, Positional Isomers Serotonergic psy., EC 50 value, NPS, LSD, phenethylamine moiety, 25 H-NBF, New Psychoactive Substances, 5- HT 2, β- arrestin 2, μ M EC 50 values, phenyl group

Relation: https://figshare.com/articles/journal_contribution/Synthesis_and_Functional_Characterization_of_2_2_5-Dimethoxyphenyl_i_N_i_2-fluorobenzyl_ethanamine_25H-NBF_Positional_Isomers/14500232

الاتاحة: https://doi.org/10.1021/acschemneuro.1c00124.s001

المؤلفون: Marthe M. Vandeputte (10427968), Katleen Van Uytfanghe (8045234), Nathan K. Layle (10427971), Danielle M. St. Germaine (10427974), Donna M. Iula (2409457), Christophe P. Stove (1235217)

مصطلحات موضوعية: Biochemistry, Neuroscience, Pharmacology, Biotechnology, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, analogue, compound, metabolite, isotonitazene, MOR activation, MS-based nitazene screening, fatality, Opioid, fentanyl, Chemical Characterization, HPLC-DAD, basis, MOR activity determination, vivo consequences, LC-QTOF-MS, diode-array detection, 2- benzylbenzimidazole opioids, retention times, absorption spectra, potency, scheduling efforts, Time-of-flight mass spectrometry

Relation: https://figshare.com/articles/journal_contribution/Synthesis_Chemical_Characterization_and_Opioid_Receptor_Activity_Assessment_of_the_Emerging_Group_of_Nitazene_2_Benzylbenzimidazole_Synthetic_Opioids/14292352

الاتاحة: https://doi.org/10.1021/acschemneuro.1c00064.s001

المؤلفون: Eline Pottie (8045231), Olga V. Kupriyanova (10197619), Asher L. Brandt (8217123), Robert B. Laprairie (315471), Vadim A. Shevyrin (10197622), Christophe P. Stove (1235217)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Pharmacology, Cancer, Mental Health, Chemical Sciences not elsewhere classified, 25 H-NBOMe Positional Isomers, methoxy groups, phenethylamine moiety, Vitro Functional Evaluation, isomers, phenylalkylamine, 5- HT 2, compound, Molecular Docking Serotonergic psyc., 2 C-X structures

Relation: https://figshare.com/articles/journal_contribution/Serotonin_2A_Receptor_5-HT_sub_2A_sub_R_Activation_by_25H-NBOMe_Positional_Isomers_i_In_Vitro_i_Functional_Evaluation_and_Molecular_Docking/14120356

الاتاحة: https://doi.org/10.1021/acsptsci.0c00189.s001

المؤلفون: René A. J. Crans, Elise Wouters, Marta Valle-León, Jaume Taura, Caio M. Massari, Víctor Fernández-Dueñas, Christophe P. Stove, Francisco Ciruela

المصدر: Frontiers in Pharmacology, Vol 11 (2020)

مصطلحات موضوعية: D2R, M1R, sumanirole, VU0255035, striatum, Parkinson’s disease, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphar.2020.00194/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/d78fedc97b28444c849c62f284c7c02b

المؤلفون: Marie H. Deventer, Mattias Persson, Antonio Laus, Eline Pottie, Annelies Cannaert, Graziella Tocco, Henrik Gréen, Christophe P. Stove

المصدر: Archives of Toxicology. 97:1367-1384

مصطلحات موضوعية: Health, Toxicology and Mutagenesis, General Medicine, Toxicology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ecf4dfaed547807d6406d4b8e9dae580
https://doi.org/10.1007/s00204-023-03465-9

المؤلفون: Sigrid Deprez, Liesl Heughebaert, Laura Boffel, Christophe P. Stove

المصدر: Clinical Chemistry and Laboratory Medicine (CCLM). 61:e87-e90

مصطلحات موضوعية: Biochemistry (medical), Clinical Biochemistry, General Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e2ccb7a587e79c1c6790bcbf454132c
https://doi.org/10.1515/cclm-2022-0864

المؤلفون: Bart Van Puyvelde, Katleen Van Uytfanghe, Laurence Van Oudenhove, Ralf Gabriels, Tessa Van Royen, Arne Matthys, Morteza Razavi, Richard Yip, Terry Pearson, Nicolas Drouin, Jan Claereboudt, Dominic Foley, Robert Wardle, Kevin Wyndham, Thomas Hankemeier, Donald Jones, Xavier Saelens, Geert Martens, Christophe P. Stove, Dieter Deforce, Lennart Martens, Johannes P.C. Vissers, N. Leigh Anderson, Maarten Dhaenens

المصدر: Analytical Chemistry. 94:17379-17387

مصطلحات موضوعية: Analytical Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a10469a4d2de32f2257dfa6ebf78bf54
https://doi.org/10.1021/acs.analchem.2c01610

المؤلفون: Lysbeth H. Antonides, Annelies Cannaert, Caitlyn Norman, Loelia Vives, Aidan Harrison, Andrew Costello, Niamh Nic Daeid, Christophe P. Stove, Oliver B. Sutcliffe, Craig McKenzie

المصدر: Frontiers in Chemistry, Vol 7 (2019)

مصطلحات موضوعية: synthetic cannabinoid receptor agonists, chiral, pharmacology, bioassay, detection, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fchem.2019.00321/full; https://doaj.org/toc/2296-2646

URL الوصول: https://doaj.org/article/7c50be3242e543ae8f506ff83921d98a

المؤلفون: Diego A. Rodríguez-Soacha, Sophie A. M. Steinmüller, Ali Işbilir, Julia Fender, Marie H. Deventer, Yesid A. Ramírez, Anna Tutov, Christoph Sotriffer, Christophe P. Stove, Kristina Lorenz, Martin J. Lohse, James N. Hislop, Michael Decker

المصدر: ACS Chemical Neuroscience. 13:2410-2435

مصطلحات موضوعية: Physiology, Cognitive Neuroscience, Cell Biology, General Medicine, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6028f60fcb3acf1ccf5236d7fc12325c
https://doi.org/10.1021/acschemneuro.2c00160