المؤلفون: Christoph Grohmann, Charlene M. Magtoto, Joel R. Walker, Ngee Kiat Chua, Anna Gabrielyan, Mary Hall, Simon A. Cobbold, Stephen Mieruszynski, Martin Brzozowski, Daniel S. Simpson, Hao Dong, Bridget Dorizzi, Annette V. Jacobsen, Emma Morrish, Natasha Silke, James M. Murphy, Joan K. Heath, Andrea Testa, Chiara Maniaci, Alessio Ciulli, Guillaume Lessene, John Silke, Rebecca Feltham

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/cbe3c5d3eff94f2bbdf917175c5d3791

المؤلفون: Hao Chen, Nghi H. Nguyen, Charlene M. Magtoto, Simon A. Cobbold, Grace M. Bidgood, Lizeth G. Meza Guzman, Lachlan W. Richardson, Jason Corbin, Amanda E. Au, Bernhard C. Lechtenberg, Rebecca Feltham, Kate D. Sutherland, Christoph Grohmann, Sandra E. Nicholson, Brad E. Sleebs

المصدر: Redox Biology, Vol 59, Iss , Pp 102552- (2023)

مصطلحات موضوعية: PROTAC, KEAP1-NRF2 pathway, Antioxidant, ROS, Oxidative stress, Medicine (General), R5-920, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S221323172200324X; https://doaj.org/toc/2213-2317

URL الوصول: https://doaj.org/article/8bf601d4ee3e4a67b3cbbfafd936ded8

المؤلفون: Christoph Grohmann, Francesca Walker, Mark Devlin, Meng-Xiao Luo, Anderly C. Chüeh, Judy Doherty, François Vaillant, Gwo-Yaw Ho, Matthew J. Wakefield, Clare E. Weeden, Alvin Kamili, Jayne Murray, Sela T. Po’uha, Janet Weinstock, Serena R. Kane, Maree C. Faux, Esmee Broekhuizen, Ye Zheng, Kristy Shield-Artin, Nadia J. Kershaw, Chin Wee Tan, Helen M. Witchard, Gregor Ebert, Susan A. Charman, Ian Street, Maria Kavallaris, Michelle Haber, Jamie I. Fletcher, Marie-Liesse Asselin-Labat, Clare L. Scott, Jane E. Visvader, Geoffrey J. Lindeman, Keith G. Watson, Antony W. Burgess, Guillaume Lessene

المصدر: Cell Death and Disease, Vol 12, Iss 3, Pp 1-18 (2021)

مصطلحات موضوعية: Cytology, QH573-671

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-4889

URL الوصول: https://doaj.org/article/041aa5232fd84ed8be1a33555359e8d7

المؤلفون: Hao Chen (5190), Yuntong Wu (11913737), Kunlun Li (11685775), Iain Currie (9929326), Narelle Keating (11913740), Farhad Dehkhoda (11913743), Christoph Grohmann (1944607), Jeffrey J. Babon (448754), Sandra E. Nicholson (448755), Brad E. Sleebs (591301)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Infectious Diseases, Virology, Biological Sciences not elsewhere classified, transcription signaling pathway, amino acid position, 5 positions within, kinase inhibitory region, respective − 1, cytokine signaling 1, src homology 2, socs1 operates via, optimized phosphotyrosine peptide, 50 , potential therapeutic target, therapeutic target, phosphotyrosine peptides, peptide substrate, janus kinase, viral diseases, values ranging, target substrate, starting point

Relation: https://figshare.com/articles/journal_contribution/Optimization_of_Phosphotyrosine_Peptides_that_Target_the_SH2_Domain_of_SOCS1_and_Block_Substrate_Ubiquitination/17936411

الاتاحة: https://doi.org/10.1021/acschembio.1c00884.s001

المؤلفون: Catia L. Pierotti, Annette V. Jacobsen, Christoph Grohmann, Ruby K. Dempsey, Nima Etemadi, Joanne M. Hildebrand, Cheree Fitzgibbon, Samuel N. Young, Katherine A. Davies, Wilhelmus J. A. Kersten, John Silke, Kym N. Lowes, Hélène Jousset Sabroux, David C. S. Huang, Mark F. van Delft, James M. Murphy, Guillaume Lessene

المصدر: Biochemical Journal. 480:665-684

مصطلحات موضوعية: Cell Biology, Molecular Biology, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a1e367c56072dc0c1f4750c019048c86
https://doi.org/10.1042/bcj20230035

المؤلفون: Hao Chen, Yuntong Wu, Kunlun Li, Iain Currie, Narelle Keating, Farhad Dehkhoda, Christoph Grohmann, Jeffrey J. Babon, Sandra E. Nicholson, Brad E. Sleebs

المصدر: ACS Chemical Biology. 17:449-462

مصطلحات موضوعية: src Homology Domains, Suppressor of Cytokine Signaling 1 Protein, Ubiquitination, Molecular Medicine, Suppressor of Cytokine Signaling Proteins, General Medicine, Phosphotyrosine, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::935ce728cbc5ff10b9029ccf66daf932
https://doi.org/10.1021/acschembio.1c00884

المؤلفون: Gregor Ebert, Danushka S. Marapana, Christoph Grohmann

المصدر: Molecular microbiologyREFERENCES. 117(3)

مصطلحات موضوعية: Drug, Proteasome Endopeptidase Complex, MICROREVIEW, MICROREVIEWS, bacteria, drug, intracellular infection, parasites, pathogenic proteins, Proteolysis2̆010targeting chimeras, resistance, viruses, Ubiquitin, media_common.quotation_subject, Ubiquitin-Protein Ligases, Ubiquitination, Proteins, Context (language use), Drug resistance, Computational biology, Protein degradation, Biology, Microbiology, Parasitic infection, Small molecule, ddc, Proteolysis, Host-pathogen interface, Treatment resistance, Molecular Biology, media_common

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fee55329facf6f262a1915b583323930
https://pubmed.ncbi.nlm.nih.gov/34816514

المؤلفون: Mark F. van Delft, Meng Xiao Luo, Kate McArthur, Peter E. Czabotar, Jarrod J. Sandow, Laura F. Dagley, Kym N Lowes, Jason M. Brouwer, Andrew I. Webb, Guillaume Lessene, Rachael M. Lane, Keith G. Watson, Christoph Grohmann, Ahmad Wardak, Peter M. Colman, Sabrina Bernard, Soo San Wan, Yelena Khakham, Phillip P. Sharp, Romina Lessene, Thao Nguyen, David J. Segal, David C.S. Huang, Erinna F. Lee, Lucy Li, Marlyse A. Debrincat, Grant Dewson, Chinh T. Bui, Hui San Chin, W. Douglas Fairlie, Stephane Duflocq, Benjamin T. Kile, Stephane Chappaz, Caroline Miles, Kurt Lackovic, Laure Peilleron

المصدر: Nature Chemical Biology. 15:1057-1066

مصطلحات موضوعية: 0303 health sciences, Programmed cell death, biology, Chemistry, 030302 biochemistry & molecular biology, Cell, Intrinsic apoptosis, Cell Biology, Mitochondrion, Cell biology, 03 medical and health sciences, medicine.anatomical_structure, Apoptosis, medicine, biology.protein, VDAC2, Molecular Biology, Bcl-2 Homologous Antagonist-Killer Protein, Caspase, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::21f8a84e9d19f8763b3963c4941664e3
https://doi.org/10.1038/s41589-019-0365-8

المؤلفون: Timothy R Blackmore, Zhong Yan Gan, Rebecca Feltham, Bernhard C. Lechtenberg, Jonathan P. Bernardini, Alan Riboldi-Tunnicliffe, Gregor Ebert, Cody C. Allison, Lachlan W Richardson, David Komander, Huib Ovaa, Theresa Klemm, Marc Pellegrini, Nathan W Kuchel, Guillaume Lessene, Kym N Lowes, Christoph Grohmann, Jeffrey P Mitchell, James P Cooney, Gerbrand J. van der Heden van Noort, Paul P. Geurink, Amanda E. Au, Grant Dewson, Marcel Doerflinger, Dale J Calleja, Peter E. Czabotar, Bernadine Gc Lu, Yuri Shibata, Janet Newman

المصدر: EMBO Journal, 39(18). WILEY
The EMBO Journal

مصطلحات موضوعية: Models, Molecular, ISG15, Protein Conformation, medicine.medical_treatment, viruses, Drug Evaluation, Preclinical, medicine.disease_cause, Crystallography, X-Ray, chemistry.chemical_compound, 0302 clinical medicine, Protein structure, Ubiquitin, Structural Biology, Chlorocebus aethiops, Coronavirus 3C Proteases, Coronavirus, 0303 health sciences, biology, General Neuroscience, small molecule inhibitor, Articles, Small molecule, Microbiology, Virology & Host Pathogen Interaction, Biochemistry, Cytokines, Fluorescence Polarization, papain-like protease, Antiviral Agents, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, COVID‐19, ubiquitin, medicine, Animals, Humans, Protease Inhibitors, Binding site, Molecular Biology, Ubiquitins, Vero Cells, 030304 developmental biology, Protease, papain‐like protease, Binding Sites, General Immunology and Microbiology, SARS-CoV-2, Drug Repositioning, Post-translational Modifications, Proteolysis & Proteomics, COVID-19, Papain, Kinetics, HEK293 Cells, chemistry, biology.protein, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e36f05a4438244e4379d16ac47d20c92
https://hdl.handle.net/1887/3182567

المؤلفون: Christoph Grohmann, Lu Bgc, Jonathan P. Bernardini, Huib Ovaa, Cody C. Allison, Gregor Ebert, Guillaume Lessene, Rebecca Feltham, Dale J Calleja, Marc Pellegrini, David Komander, T. Klemm, Mitchell Jp, Kym N Lowes, Bernhard C. Lechtenberg, James P Cooney, Peter E. Czabotar, Amanda E. Au, Zhong Yan Gan, Paul P. Geurink, Kuchel Nw, Janet Newman, Yuri Shibata, Blackmore Tr, L.W. Richardson, Grant Dewson, Marcel Doerflinger, Alan Riboldi-Tunnicliffe

مصطلحات موضوعية: Proteases, Innate immune system, Protease, biology, Ubiquitin binding, Chemistry, medicine.medical_treatment, ISG15, Cell biology, Viral replication, Ubiquitin, biology.protein, medicine, Binding site

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::bf71356e1581ef4bb08f30febabebb6e
https://doi.org/10.1101/2020.06.18.160614

المؤلفون: Christoph Grohmann, Frank Glorius, Honggen Wang

المصدر: Organic Letters. 15:3014-3017

مصطلحات موضوعية: Molecular Structure, Formic Acid Esters, Chemistry, Organic Chemistry, Hydroxamic Acids, Biochemistry, Medicinal chemistry, Catalysis, chemistry.chemical_compound, Pyridine, Electrophile, Functional group, Organic chemistry, Molecule, Rhodium, Carbamates, Amines, Physical and Theoretical Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0af462f54e5f74f6532c741c255f51
https://doi.org/10.1021/ol401209f

المؤلفون: Frank Glorius, Zhuangzhi Shi, Christoph Grohmann

المصدر: Angewandte Chemie. 125:5503-5507

مصطلحات موضوعية: Chemistry, General Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::14d39bca6d7b52465f75c4fb908cb2b0
https://doi.org/10.1002/ange.201301426

المؤلفون: Mark F, van Delft, Stephane, Chappaz, Yelena, Khakham, Chinh T, Bui, Marlyse A, Debrincat, Kym N, Lowes, Jason M, Brouwer, Christoph, Grohmann, Phillip P, Sharp, Laura F, Dagley, Lucy, Li, Kate, McArthur, Meng-Xiao, Luo, Hui San, Chin, W Douglas, Fairlie, Erinna F, Lee, David, Segal, Stephane, Duflocq, Romina, Lessene, Sabrina, Bernard, Laure, Peilleron, Thao, Nguyen, Caroline, Miles, Soo San, Wan, Rachael M, Lane, Ahmad, Wardak, Kurt, Lackovic, Peter M, Colman, Jarrod J, Sandow, Andrew I, Webb, Peter E, Czabotar, Grant, Dewson, Keith G, Watson, David C S, Huang, Guillaume, Lessene, Benjamin T, Kile

المصدر: Nature chemical biology. 15(11)

مصطلحات موضوعية: Small Molecule Libraries, Mice, bcl-2 Homologous Antagonist-Killer Protein, Voltage-Dependent Anion Channel 2, Animals, Apoptosis, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::0477b40e4e5384654fad1f5b446d351b
https://pubmed.ncbi.nlm.nih.gov/31591564

المؤلفون: Honggen Wang, Christoph Grohmann, Corinna Nimphius, Frank Glorius

المصدر: Journal of the American Chemical Society. 134:19592-19595

مصطلحات موضوعية: chemistry.chemical_classification, Indole test, Annulation, Alkyne, General Chemistry, Biochemistry, Combinatorial chemistry, Catalysis, chemistry.chemical_compound, Colloid and Surface Chemistry, chemistry, Organic chemistry, Isoquinoline, Boronic acid, Pyrrole

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeea757d706e9d2a4cc98657de458594
https://doi.org/10.1021/ja310153v

المؤلفون: Kazuyuki Tatsumi, Yasuhiro Ohki, Christoph Grohmann, Takayoshi Hashimoto, Frank Glorius, Roland Fröhlich

المصدر: Organometallics

مصطلحات موضوعية: 010405 organic chemistry, Ligand, Hydrosilylation, Organic Chemistry, 010402 general chemistry, Photochemistry, 01 natural sciences, Chloride, 3. Good health, 0104 chemical sciences, Inorganic Chemistry, chemistry.chemical_compound, Deprotonation, chemistry, Diamine, Octahedral molecular geometry, Polymer chemistry, medicine, Physical and Theoretical Chemistry, Trifluoromethanesulfonate, Carbene, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56262e445f1727740dc169ff571990fc
https://doi.org/10.1021/om300888q

المؤلفون: Christoph Grohmann, Honggen Wang, Frank Glorius

المصدر: Organic Letters. 14:656-659

مصطلحات موضوعية: chemistry.chemical_compound, Chemistry, Organic Chemistry, Organic chemistry, Physical and Theoretical Chemistry, Benzamide, Biochemistry, Amination, Catalysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a25f38ece8bdb5d580b6f48b86681c40
https://doi.org/10.1021/ol203353a

المؤلفون: Christoph Grohmann, Tatiana Besset, Souvik Rakshit, Frank Glorius

المصدر: Journal of the American Chemical Society. 133:2350-2353

مصطلحات موضوعية: Molecular Structure, Stereochemistry, Substituent, Stereoisomerism, Oxidation reduction, General Chemistry, Alkenes, Biochemistry, Combinatorial chemistry, Catalysis, chemistry.chemical_compound, Colloid and Surface Chemistry, chemistry, Group (periodic table), Benzamides, Oxidizing agent, Molecule, Rhodium, Oxidation-Reduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3586aadc5d8d63ac5a27dbaaa418adf
https://doi.org/10.1021/ja109676d

المؤلفون: Colleen M. Connelly, Alexander Deiters, Christoph Grohmann, Douglas D. Young

المصدر: Journal of the American Chemical Society. 132:7976-7981

مصطلحات موضوعية: Enoxacin, Carcinoma, Hepatocellular, Hepatitis C virus, Apoptosis, Virus Replication, medicine.disease_cause, Biochemistry, Catalysis, Colloid and Surface Chemistry, microRNA, MiR-122, medicine, Humans, Base Sequence, Chemistry, Liver Neoplasms, Cancer, General Chemistry, Oligonucleotides, Antisense, medicine.disease, Hepatitis C, Small molecule, MicroRNAs, Viral replication, Hepatocellular carcinoma, Cancer research, Liver cancer, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3765ae1b82d8ce7423dee69052ede73
https://doi.org/10.1021/ja910275u

المؤلفون: Christoph Grohmann, Honggen Wang, Frank Glorius

المصدر: ChemInform. 44

مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Functional group, General Medicine, Medicinal chemistry, Thiophene derivatives, Catalysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::f93ecb4cbd1b16cc25b71c962da48f96
https://doi.org/10.1002/chin.201348073

المؤلفون: Christoph Grohmann, Zhuangzhi Shi, Frank Glorius

المصدر: ChemInform. 44

مصطلحات موضوعية: Annulation, chemistry, Intramolecular force, chemistry.chemical_element, General Medicine, Medicinal chemistry, Rhodium, Catalysis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c80b7db2d347beae8e452ba8ccc35b5c
https://doi.org/10.1002/chin.201342179