المؤلفون: Christina Tzitzoglaki, Anja Hoffmann, Andreea L. Turcu, Patrick Schmerer, Chunlong Ma, George Laros, Christos Liolios, Brea José, Jun Wang, Santiago Vázquez, Michaela Schmidtke, Antonios Kolocouris

المصدر: European Journal of Medicinal Chemistry Reports, Vol 6, Iss , Pp 100083- (2022)

مصطلحات موضوعية: Amantadine - aryl conjugate, In vitro ​antiviral activity, CPE, Electrophysiology, Influenza A M2 protein, A30T, Pharmacy and materia medica, RS1-441, Other systems of medicine, RZ201-999

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2772417422000553; https://doaj.org/toc/2772-4174

URL الوصول: https://doaj.org/article/61d646d119f84656a795a2586c903bd3

المؤلفون: Michaela Schmidtke, Andreea L. Turcu, Anja Hoffmann, Patrick Schmerer, Jun Wang, Antonios Kolocouris, Christos Liolios, Christina Tzitzoglaki, Chunlong Ma, Santiago Vázquez

مصطلحات موضوعية: chemistry.chemical_compound, Viral replication, Rimantadine, Chemistry, Adamantane, Mutant, Amantadine, medicine, Virology, Virus, In vitro, medicine.drug, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b19f8744cc0c7f25135efc3c695c0379
https://doi.org/10.26434/chemrxiv-2021-42fvb

المؤلفون: Μarianna Stampolaki, Christina Tzitzoglaki, Christos Liolios, Anja Hoffmann, Brent Johnson, Ioannis Stylianakis, Roland Zell, Andreea Turcu, Patrick Schmerer, Kristin Döring, Chunlong Ma, Ivi Theodosia Antoniadou, David Fedida, Fransesc Sureda, Stephen Wharton, Jun Wang, Santiago Vázquez, Michaela Schmidtke, Antonios Kolocouris

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b8b9be4b2ce95089faa6cf256fab55b1
https://doi.org/10.26434/chemrxiv-2021-5dqxx

المؤلفون: Jun Wang, David D. Busath, Kelly L. McGuire, Natalie A. Fokina, Peter R. Schreiner, Panagiotis Lagarias, Anja Hoffmann, Athina Konstantinidi, Antonios Kolocouris, Chunlong Ma, Ioannis Papanastasiou, Christina Tzitzoglaki, Santiago Vázquez, Michaela Schmidtke

المصدر: ACS Chem Biol
Dipòsit Digital de la UB
Universidad de Barcelona
ACS Chemical Biology

مصطلحات موضوعية: Drug targeting, Síntesi orgànica, Rimantadine, Stereochemistry, Adamantane, Pneumonia, Viral, Organic chemistry, Organic synthesis, Química farmacèutica, medicine.disease_cause, Virus Replication, Biochemistry, Influenzavirus, Ion Channels, Article, Viral Matrix Proteins, chemistry.chemical_compound, Betacoronavirus, Structure-Activity Relationship, Influenza, Human, Influenza A virus, medicine, Influenza viruses, Humans, Binding site, Pandemics, Cells, Cultured, Binding Sites, SARS-CoV-2, Aryl, COVID-19, Genetic Variation, Chloroquine, General Medicine, Ligand (biochemistry), Receptor–ligand kinetics, Kinetics, Dianes farmacològiques, chemistry, Molecular Probes, Molecular Medicine, Coronavirus Infections, Diamantane, Química orgànica, Pharmaceutical chemistry, medicine.drug, Protein Binding

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ef7280f17ddc12bffc544f168c1c95c
https://pubmed.ncbi.nlm.nih.gov/32786258

المؤلفون: Anja Hoffmann, David D. Busath, Michaela Schmidtke, Dimitrios Kolokouris, Johanna Hutterer, Jun Wang, Kelly L. McGuire, Kathrin Freudenberger, Antonios Drakopoulos, Christina Tzitzoglaki, Günter Gauglitz, Chunlong Ma, Athina Konstantinidi, Antonios Kolocouris

المصدر: ACS Medicinal Chemistry Letters. 9:198-203

مصطلحات موضوعية: 0301 basic medicine, Rimantadine, Chemistry, Organic Chemistry, Wild type, Isothermal titration calorimetry, 010402 general chemistry, medicine.disease_cause, 01 natural sciences, Biochemistry, Small molecule, Receptor–ligand kinetics, 0104 chemical sciences, 03 medical and health sciences, 030104 developmental biology, Drug Discovery, medicine, Influenza A virus, Biophysics, Potency, Enantiomer, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::723ac986327427b5ea6bfd2ece2cf80d
https://doi.org/10.1021/acsmedchemlett.7b00458

المؤلفون: Kelly L. McGuire, Michaela Schmidtke, Anja Hoffmann, Antonios Kolocouris, Christina Tzitzoglaki, Schreiner Pr, Busath D, Papanastasiou I, Jun Wang, Santiago Vázquez, Fokina Na, Athina Konstantinidi, Panagiotis Lagarias

مصطلحات موضوعية: Chemistry, Blocking (radio), Combinatorial chemistry, Receptor–ligand kinetics, Conjugate

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c55a4500eea7215de924342a0cd1f37
https://doi.org/10.26434/chemrxiv.11494170

المؤلفون: Timothy A. Cross, Kathrin Freudenberger, Antonios Kolocouris, Anja Hoffmann, Ioannis Stylianakis, Ian Tietjen, Felix Kolarov, Anna K. Wright, David Fedida, Christina Tzitzoglaki, Günter Gauglitz, Michaela Schmidtke

المصدر: J Med Chem

مصطلحات موضوعية: 0301 basic medicine, Proton, Ligands, 010402 general chemistry, Antiviral Agents, 01 natural sciences, Article, Viral Matrix Proteins, 03 medical and health sciences, Molecular dynamics, Drug Discovery, Amantadine, biology, Chemistry, Spectrum Analysis, Bilayer, Conductance, Isothermal titration calorimetry, Ligand (biochemistry), 0104 chemical sciences, Crystallography, 030104 developmental biology, Solid-state nuclear magnetic resonance, M2 proton channel, Influenza A virus, biology.protein, Molecular Medicine, Protons

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bde8a912b66758bd58cd7aa7f928801
https://doi.org/10.1021/acs.jmedchem.6b01115

المؤلفون: Mazzanti, Andrea, Drakopoulos, Antonios, Christina, Tzitzoglaki, Kolocouris, Antonios

المصدر: ChemistrySelect ; volume 4, issue 25, page 7645-7648 ; ISSN 2365-6549 2365-6549

الاتاحة: http://dx.doi.org/10.1002/slct.201901042
https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1002%2Fslct.201901042
https://onlinelibrary.wiley.com/doi/pdf/10.1002/slct.201901042
https://onlinelibrary.wiley.com/doi/full-xml/10.1002/slct.201901042

المؤلفون: Antonios Kolocouris, Felix Kolarov, Kathrin Freudenberger, Paraskevi Gkeka, Zoe Cournia, Christos Liolios, Harris Ioannidis, Holger Gohlke, Christina Tzitzoglaki, Günter Gauglitz, Nadine Homeyer, Antonios Drakopoulos

المصدر: Journal of Chemical Information and Modeling. 56:862-876

مصطلحات موضوعية: 0301 basic medicine, Rimantadine, Entropy, General Chemical Engineering, Adamantane, Calorimetry, Molecular Dynamics Simulation, Library and Information Sciences, 010402 general chemistry, medicine.disease_cause, 01 natural sciences, Viral Matrix Proteins, 03 medical and health sciences, chemistry.chemical_compound, Protein Domains, Tetramer, Bennett acceptance ratio, medicine, Influenza A virus, Humans, Amino Acid Sequence, Chemistry, Cell Membrane, Temperature, Amantadine, Stereoisomerism, Isothermal titration calorimetry, General Chemistry, 0104 chemical sciences, Computer Science Applications, Crystallography, 030104 developmental biology, Protons, Protein Binding, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::500930f123e6ae64ba87c1e66d4f1ccd
https://doi.org/10.1021/acs.jcim.6b00079

المؤلفون: F. Brent Johnson, Antonios Kolocouris, Timothy A. Cross, David D. Busath, Ian Tietjen, Anna K. Wright, David Fedida, Roland Zell, Christina Tzitzoglaki

المصدر: Journal of Medicinal Chemistry

مصطلحات موضوعية: Rimantadine, Adamantane, 010402 general chemistry, medicine.disease_cause, 01 natural sciences, Antiviral Agents, Article, Ion Channels, Madin Darby Canine Kidney Cells, Viral Matrix Proteins, 03 medical and health sciences, chemistry.chemical_compound, Dogs, Influenza A Virus, H1N1 Subtype, Drug Resistance, Multiple, Viral, Drug Discovery, medicine, Amantadine, Animals, Humans, 030304 developmental biology, 0303 health sciences, Mutation, biology, Chemistry, HEK 293 cells, Virology, In vitro, 3. Good health, 0104 chemical sciences, Transmembrane domain, HEK293 Cells, M2 proton channel, biology.protein, Molecular Medicine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba4e9759d7abe18b578c32d76f7d1d0e
http://europepmc.org/articles/PMC4127532

المؤلفون: Christina Tzitzoglaki, Ioannis Stylianakis, Athina Konstantinidi, Marianna Stampolaki, Antonios Kolocouris, Antonios Drakopoulos

المصدر: Tetrahedron. 75:130408

مصطلحات موضوعية: chemistry.chemical_classification, Primary (chemistry), 010405 organic chemistry, Aryl, Adamantane, Organic Chemistry, 010402 general chemistry, 01 natural sciences, Biochemistry, Ritter reaction, 0104 chemical sciences, Adduct, chemistry.chemical_compound, chemistry, Reagent, Drug Discovery, Organic chemistry, Lewis acids and bases, Alkyl

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9ade6454c7a96513a924ce2238112110
https://doi.org/10.1016/j.tet.2019.06.016

المؤلفون: Antonios Drakopoulos, Jun Wang, Antonios Kolocouris, Anja Hoffmann, Michaela Schmidtke, Guenter Gauglitz, Chulong Ma, Kathrin Freudenberger, Christina Tzitzoglaki, Yanmei Hu

مصطلحات موضوعية: 0301 basic medicine, Chromatography, Rimantadine, Chemistry, Stereochemistry, Organic Chemistry, Significant difference, Influenza a, Isothermal titration calorimetry, 010402 general chemistry, 01 natural sciences, Biochemistry, 0104 chemical sciences, Free energy perturbation, 03 medical and health sciences, 030104 developmental biology, Solid-state nuclear magnetic resonance, Drug Discovery, medicine, Potency, Enantiomer, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ff63d942413d356dbec40ce2d63663
https://europepmc.org/articles/PMC5312807/

المؤلفون: Mazzanti, Andrea, Drakopoulos, Antonios, Christina, Tzitzoglaki, Kolocouris, Antonios

المصدر: ChemistrySelect; 7/5/2019, Vol. 4 Issue 25, p7645-7648, 4p

مصطلحات موضوعية: ROTATIONAL motion, DRUG design, FOREIGN exchange rates, SPECTRUM analysis, LOW temperatures, FARADAY effect

المؤلفون: Michaela Schmidtke, Marta López-Querol, Roland Zell, Harris Ioannidis, Francesc X. Sureda, Christina Tzitzoglaki, Kelly L. McGuire, Timothy A. Cross, Anna K. Wright, Anja Hoffman, F. Brent Johnson, David D. Busath, Daniel C Kwan, David Fedida, Antonios Kolocouris

المصدر: Biophysical Journal. 106:432a-433a

مصطلحات موضوعية: congenital, hereditary, and neonatal diseases and abnormalities, biology, Endosome, viruses, Mutant, HEK 293 cells, Biophysics, Amantadine, Hemagglutinin (influenza), Virology, Virus, 3. Good health, Mechanism of action, cardiovascular system, medicine, biology.protein, medicine.symptom, medicine.drug, Cytopathic effect

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87d1e4a93360247e2dae8b30e2fb4d45
https://doi.org/10.1016/j.bpj.2013.11.2435

المؤلفون: Harris Ioannidis, Christina Tzitzoglaki, David D. Busath, Timothy A. Cross, Anna K. Wright, Ivan Hung, Antonios Kolocouris

المصدر: Biophysical Journal. 106:659a

مصطلحات موضوعية: biology, Chemistry, Stereochemistry, Bilayer, Adamantane, Biophysics, Drug design, Transmembrane domain, chemistry.chemical_compound, Solid-state nuclear magnetic resonance, M2 proton channel, Magic angle spinning, biology.protein, Lipid bilayer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdd5c02a81d914ba41aac1c86ed6516b
https://doi.org/10.1016/j.bpj.2013.11.3651

المؤلفون: Antonios Kolocouris, Brent Johnson, Christina Tzitzoglaki, Nathan C. Gay, David D. Busath

المصدر: Biophysical Journal. 104:277a

مصطلحات موضوعية: Mutation, biology, Rimantadine, Strain (chemistry), Biophysics, Amantadine, Wild type, medicine.disease_cause, Virology, Virus, M2 proton channel, Viral replication, medicine, biology.protein, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad7d132ffb54dfbbec4e05111b7628ca
https://doi.org/10.1016/j.bpj.2012.11.1555