المؤلفون: Thomas Hermanns, Christian Pichlo, Ulrich Baumann, Kay Hofmann

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/7e2953b296d9430397012536020fd7cf

المؤلفون: Sabine Ruegenberg, Moritz Horn, Christian Pichlo, Kira Allmeroth, Ulrich Baumann, Martin S. Denzel

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/e59e6a5f14a34fdf901be6fbcaf41cc6

المؤلفون: Thomas Hermanns, Christian Pichlo, Ilka Woiwode, Karsten Klopffleisch, Katharina F. Witting, Huib Ovaa, Ulrich Baumann, Kay Hofmann

المصدر: Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/ee7d765deef64ba6a8f81356743f0721

المؤلفون: Andreas Luxenburger, Dorian Schmidt, Chiara Ianes, Christian Pichlo, Marc Krüger, Thorsten von Drathen, Elena Brunstein, Graeme J. Gainsford, Ulrich Baumann, Uwe Knippschild, Christian Peifer

المصدر: Molecules, Vol 24, Iss 5, p 873 (2019)

مصطلحات موضوعية: protein kinase CK1, formerly known as casein kinase 1, chiral kinase inhibitors, iminoribitol, ribose pocket, 3,4-diaryl-isoxazole, Pictet-Spengler cyclization, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: http://www.mdpi.com/1420-3049/24/5/873; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/d440f729899d4674be885230fa1ca581

المؤلفون: Andreas Luxenburger, Dorian Schmidt, Chiara Ianes, Christian Pichlo, Marc Krüger, Thorsten von Drathen, Elena Brunstein, Graeme Gainsford, Ulrich Baumann, Uwe Knippschild, Christian Peifer

مصطلحات موضوعية: Uncategorized, Uncategorised value

Relation: https://figshare.com/articles/conference_contribution/IMINORIBITOL-MODIFIED_3_4-DIARYL-ISOXAZOLES_AS_POTENT_INHIBITORS_OF_CK1_/21892899

الاتاحة: https://doi.org/10.25455/wgtn.21892899
https://figshare.com/articles/conference_contribution/IMINORIBITOL-MODIFIED_3_4-DIARYL-ISOXAZOLES_AS_POTENT_INHIBITORS_OF_CK1_/21892899

المؤلفون: Fabian, Wesseler, Stefan, Lohmann, Daniel, Riege, Jonas, Halver, Aileen, Roth, Christian, Pichlo, Sabrina, Weber, Masanari, Takamiya, Eva, Müller, Jana, Ketzel, Jana, Flegel, Adrian, Gihring, Sepand, Rastegar, Jessica, Bertrand, Ulrich, Baumann, Uwe, Knippschild, Christian, Peifer, Sonja, Sievers, Herbert, Waldmann, Dennis, Schade

المصدر: Journal of medicinal chemistry. 65(22)

مصطلحات موضوعية: Osteogenesis, Bone Morphogenetic Proteins, Quinazolines, Bone Morphogenetic Protein 2, Cell Differentiation, Smad Proteins, Triazoles

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::53d19e5610a77547a06f8e4aaca04395
https://pubmed.ncbi.nlm.nih.gov/36346705

المؤلفون: Jakob Halekotte, Lydia Witt, Chiara Ianes, Marc Krüger, Mike Bührmann, Daniel Rauh, Christian Pichlo, Elena Brunstein, Andreas Luxenburger, Ulrich Baumann, Uwe Knippschild, Joachim Bischof, Christian Peifer

المصدر: Molecules; Volume 22; Issue 4; Pages: 522

مصطلحات موضوعية: protein kinase CK1, formerly known as casein kinase 1, p38 MAPK, kinase inhibitors, 4,5-diaryl-imidazoles, Alzheimer’s disease, amyotrophic lateral sclerosis, familial advanced sleep phase syndrome, cancer

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Medicinal Chemistry; https://dx.doi.org/10.3390/molecules22040522

الاتاحة: https://doi.org/10.3390/molecules22040522

المؤلفون: Jan Riemer, Muna Ali, Sarah Gerlich, Ulrich Baumann, Kim Jasmin Lapacz, Sophia Urbanczyk, Bent Brachvogel, Dirk Mielenz, Carmelina Petrungaro, Yannik Finger, Julian Koch, Laura Schu, Erik van de Logt, Christian Pichlo, Joern Dengjel, Silja Lucia Salscheider, Kay Hofmann, Markus Habich

المصدر: The EMBO Journal

مصطلحات موضوعية: Proteasome Endopeptidase Complex, Mitochondrion, Biology, General Biochemistry, Genetics and Molecular Biology, Article, Mitochondrial Proteins, 03 medical and health sciences, 0302 clinical medicine, Dipeptidyl Peptidase 9, dipeptidyl peptidase 9, Humans, quality control, Membrane & Intracellular Transport, Dipeptidyl-Peptidases and Tripeptidyl-Peptidases, Molecular Biology, Mitochondrial protein, 030304 developmental biology, 0303 health sciences, General Immunology and Microbiology, General Neuroscience, Adenylate Kinase, Mitochondrial protein import, Articles, mitochondrial protein import, AK2, Cell biology, Cytosol, Protein Transport, HEK293 Cells, MIA40, Proteome, Proteolysis, Degradation (geology), adenylate kinase 2, 030217 neurology & neurosurgery, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d41a2e9f9f7c6dd9fc4ceed79980a7cc
http://doc.rero.ch/record/329395/files/descr.txt

المؤلفون: Magdalena Schacherl, Christian Pichlo, Denzel, Thomas Hermanns, Matthias Uthoff, Christine Toelzer, S. Ocal, S. Ruegenberg, K. Chojnacki, Kay Hofmann, Karsten Niefind, Ulrich Baumann

المصدر: Acta Crystallogr F Struct Biol Commun

مصطلحات موضوعية: 0301 basic medicine, 2,2,2-Trichloroethanol, Microscope, Biophysics, Ethylene Chlorohydrin, Salt (chemistry), Biochemistry, Protein Structure, Secondary, Research Communications, law.invention, 03 medical and health sciences, chemistry.chemical_compound, Structural Biology, law, Hydrolase, Genetics, Crystallization, Enhancer, chemistry.chemical_classification, Chemistry, Condensed Matter Physics, Fluorescence, Combinatorial chemistry, Recombinant Proteins, 030104 developmental biology, Microscopy, Fluorescence, Protein crystallization

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25bd7ce3e87f98a0c804f0262e7ff4f3
https://doi.org/10.1107/s2053230x18005253

المؤلفون: Christian, Pichlo, Linda, Juetten, Fabian, Wojtalla, Magdalena, Schacherl, Dolores, Diaz, Ulrich, Baumann

المصدر: J Biol Chem

مصطلحات موضوعية: Kinetics, Bacterial Proteins, Proline, Clostridioides difficile, Protein Conformation, Endopeptidases, Proteolysis, Enzymology, Hydrogen Bonding, Substrate Specificity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::ae8d9a346a96713ff523eb82b403a311
https://pubmed.ncbi.nlm.nih.gov/31182482

المؤلفون: Miriam Schehr, Chiara Lanes, Jörn Weisner, Linda Heintze, Matthias P. Müller, Christian Pichlo, Julia Charl, Elena Brunstein, Julia Ewert, Marc Lehr, Ulrich Baumann, Daniel Rauh, Uwe Knippschild, Christian Peifer, Rainer Herges

المصدر: Photochemicalphotobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology. 18(6)

مصطلحات موضوعية: Mitogen-Activated Protein Kinase 14, Models, Molecular, Structure-Activity Relationship, Thiazoles, Dose-Response Relationship, Drug, Molecular Structure, Casein Kinase Idelta, Imidazoles, Physical and Theoretical Chemistry, Ligands, Photochemical Processes, Azocines, Protein Kinase Inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c947dd1a5f5a20caab04ab42dde26170
https://pubmed.ncbi.nlm.nih.gov/30924488

المؤلفون: Fatih Demir, Ulrich Baumann, Christian Pichlo, Jacqueline Lange, Eric von Elert, Pitter F. Huesgen

المصدر: Aquatic toxicology 205, 140-147 (2018). doi:10.1016/j.aquatox.2018.09.013

مصطلحات موضوعية: 0106 biological sciences, 0301 basic medicine, Proteomics, Proteases, Health, Toxicology and Mutagenesis, medicine.medical_treatment, Daphnia magna, Aquatic Science, Cyanobacteria, 01 natural sciences, Serine, 03 medical and health sciences, ddc:570, Zymogen, medicine, Animals, Serine protease, Protease, biology, Chemistry, 010604 marine biology & hydrobiology, fungi, Proteolytic enzymes, biology.organism_classification, 030104 developmental biology, Biochemistry, Daphnia, biology.protein, Heterologous expression, Serine Proteases, Water Pollutants, Chemical

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f2b66182561708a84fad9a39a146af
https://pubmed.ncbi.nlm.nih.gov/30384195

المؤلفون: Fabian Wesseler, Uwe Knippschild, Dennis Schade, Balbina García-Reyes, Bernd Rathmer, Elena Brunstein, Christian Pichlo, Doris Henne-Bruns, Björn Jansen, Tanja Gehring, Ebru Karasu, Lydia Witt, Ulrich Baumann, Christian Peifer, Johann Leban

المصدر: Journal of medicinal chemistry. 61(9)

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Casein Kinase 1 epsilon, Protein Conformation, Mutant, Binding, Competitive, 03 medical and health sciences, 0302 clinical medicine, Adenosine Triphosphate, Palmitoylation, Cell Line, Tumor, Drug Discovery, Transferase, Humans, Protein Kinase Inhibitors, Cell Proliferation, Kinase, Chemistry, Wnt signaling pathway, Ligand (biochemistry), PORCN, Wnt Proteins, 030104 developmental biology, Biochemistry, 030220 oncology & carcinogenesis, Casein Kinase Idelta, Drug Design, Molecular Medicine, Benzimidazoles, Casein kinase 1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93411feea3b63a252c669e04fefebccf
https://pubmed.ncbi.nlm.nih.gov/29630366

المؤلفون: Daniel Rauh, Christian Peifer, Joachim Bischof, Mike Bührmann, Christian Pichlo, Andreas Luxenburger, Marc Krüger, Ulrich Baumann, Chiara Ianes, Jakob Halekotte, Lydia Witt, Uwe Knippschild, Elena Brunstein

المصدر: Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules; Volume 22; Issue 4; Pages: 522

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, amyotrophic lateral sclerosis, Pharmaceutical Science, Crystallography, X-Ray, Analytical Chemistry, Pathogenesis, Mitogen-Activated Protein Kinase 14, 0302 clinical medicine, Adenosine Triphosphate, 4,5-diaryl-imidazoles, Drug Discovery, kinase inhibitors, Phylogeny, Kinase, Imidazoles, Alzheimer's disease, Small molecule, Biochemistry, Chemistry (miscellaneous), 030220 oncology & carcinogenesis, Casein Kinase Idelta, Molecular Medicine, Casein kinase 1, Alzheimer’s disease, Gene isoform, familial advanced sleep phase syndrome, Biology, p38 MAPK, Article, 03 medical and health sciences, Inhibitory Concentration 50, Cell Line, Tumor, medicine, Humans, cancer, Physical and Theoretical Chemistry, Protein kinase A, IC50, Protein Kinase Inhibitors, protein kinase CK1, formerly known as casein kinase 1, Organic Chemistry, Cancer, medicine.disease, 030104 developmental biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b8a11cd817793c3b2a0a29e7eed04c9
https://pubmed.ncbi.nlm.nih.gov/28338621

المؤلفون: Christian, Pichlo, Angelika A, Montada, Magdalena, Schacherl, Ulrich, Baumann

المصدر: Journal of visualized experiments : JoVE. (118)

مصطلحات موضوعية: Zinc, Bacterial Proteins, Clostridioides difficile, Escherichia coli, Metalloproteases, Crystallization, Crystallography, X-Ray, Biochemistry, Recombinant Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::1094f98fd7c130be1605e826593359c5
https://pubmed.ncbi.nlm.nih.gov/28060332

المؤلفون: Angelika A. M. Montada, Ulrich Baumann, Magdalena Schacherl, Christian Pichlo

المصدر: Journal of Visualized Experiments.

مصطلحات موضوعية: 0301 basic medicine, General Immunology and Microbiology, General Chemical Engineering, General Neuroscience, chemistry.chemical_element, Virulence, Zinc, Biology, medicine.disease_cause, C difficile, Virulence factor, General Biochemistry, Genetics and Molecular Biology, law.invention, 03 medical and health sciences, 030104 developmental biology, chemistry, Biochemistry, law, medicine, Recombinant DNA, Crystallization, Escherichia coli, Pathogen

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e8a36b4e487381a3824806142d1e3b
https://doi.org/10.3791/55022-v

المؤلفون: Ines Neundorf, Christian Pichlo, Magdalena Schacherl, Ulrich Baumann

المصدر: Structure (London, England : 1993). 23(9)

مصطلحات موضوعية: Models, Molecular, Proline, medicine.disease_cause, Protein Structure, Secondary, Microbiology, Substrate Specificity, 03 medical and health sciences, Bacterial Proteins, Structural Biology, Catalytic Domain, Hydrolase, medicine, Extracellular, Peptide bond, Molecular Biology, 030304 developmental biology, 0303 health sciences, Metalloproteinase, biology, Clostridioides difficile, 030302 biochemistry & molecular biology, Pathogenic bacteria, Clostridium difficile, biology.organism_classification, Bacillus anthracis, Biochemistry, Metalloproteases, Peptides

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa694cf0f1c6c81929b6957375d4777b
https://pubmed.ncbi.nlm.nih.gov/26211609

المؤلفون: Svenja Schneider, Eva Janzen, Natalia Mendoza-Ferreira, Janine Milbradt, Matthias Hammerschmidt, Mert Karakaya, Marie Coutelier, Alexis Brice, Brunhilde Wirth, Stephan Züchner, Alexandra Durr, Andrew B. Singleton, Christian Pichlo, Seyyedmohsen Hosseinibarkooie, Giovanni Stevanin, Markus Riessland, Heiko Löhr, Laura Torres-Benito

المصدر: Neurology: Genetics

مصطلحات موضوعية: 0301 basic medicine, Ataxia, Mutant, medicine.disease_cause, Article, 03 medical and health sciences, Genetic linkage, medicine, Zebrafish, Cerebellar hypoplasia, Genetics (clinical), Genetics, Mutation, biology, Autosomal recessive cerebellar ataxia, biology.organism_classification, medicine.disease, 030104 developmental biology, Cerebellar atrophy, Neurology (clinical), medicine.symptom

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98afa88732750b218c53530640778e96
https://doi.org/10.1212/nxg.0000000000000209

المؤلفون: Fabian Wojtalla, Ulrich Baumann, Magdalena Schacherl, Dolores Díaz, Linda Juetten, Christian Pichlo

المصدر: JBC papers in press 294(30), 11525-11535 (2019). doi:10.1074/jbc.RA119.009029
Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, Metalloproteinase, Protease, 030102 biochemistry & molecular biology, medicine.diagnostic_test, Chemistry, medicine.medical_treatment, Proteolysis, Cell Biology, Biochemistry, 3. Good health, 03 medical and health sciences, 030104 developmental biology, Protein structure, Hydrolase, medicine, Consensus sequence, Peptide bond, Enzyme kinetics, ddc:610, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa9cc8a51d4c1b6ff9c59574c1c76334