المؤلفون: Christian M. Apfel, Hans Locher, Stefan Evers, Béla Takács, Christian Hubschwerlen, Wolfgang Pirson, Malcolm G. P, Wolfgang Keck, Malcolm G. P. Page

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://aac.asm.org/content/45/4/1058.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.324.2795; http://aac.asm.org/content/45/4/1058.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.324.2795
http://aac.asm.org/content/45/4/1058.full.pdf

المؤلفون: Intact Cells Cell, Christian M. Apfel, Stefan Evers, Christian Hubschwerlen, Wolfgang Pirson, Wolfgang Keck, Cell Homogenates, Intact Cells, Malcolm G. P. Page

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://aac.asm.org/content/45/4/1053.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.329.8258; http://aac.asm.org/content/45/4/1053.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.329.8258
http://aac.asm.org/content/45/4/1053.full.pdf

المؤلفون: Undecaprenyl Pyrophosphate Synthetase, Christian M. Apfel, Béla Takács, Michael Fountoulakis, Martin Stieger, Wolfgang Keck

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://jb.asm.org/content/181/2/483.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.334.9271; http://jb.asm.org/content/181/2/483.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.334.9271
http://jb.asm.org/content/181/2/483.full.pdf

المؤلفون: M. Kammermann, H. Dehmlow, Christian M. Apfel, Uwe Grether, Cornelia Hertel, Athanasios Denelavas, A. Imbach

المصدر: Biochemical and Biophysical Research Communications. 412:419-424

مصطلحات موضوعية: medicine.medical_specialty, Biophysics, Vasodilation, Receptors, Nicotinic, Ligands, Niacin, Biochemistry, Cell Line, Receptors, G-Protein-Coupled, Mice, chemistry.chemical_compound, Internal medicine, Electric Impedance, medicine, Animals, Humans, Receptor, Molecular Biology, Triglycerides, Triglyceride, Ligand, Chemistry, digestive, oral, and skin physiology, Cell Biology, Coupling (electronics), Endocrinology, Nicotinic agonist, Signal transduction, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::566603bd32b9aa307e89731f4ae81285
https://doi.org/10.1016/j.bbrc.2011.07.087

المؤلفون: Christian M. Apfel, Thilo Enderle

المصدر: Combinatorial Chemistry: From Theory to Application, Volume 26, Second Revised Edition

مصطلحات موضوعية: Chemistry, Drug discovery, High-throughput screening, Computational biology, Combinatorial chemistry, Colorimetry (chemical method)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::27438d7193e7d9def40bf541a73a1e1c
https://doi.org/10.1002/3527607706.ch10

المؤلفون: Christian M. Apfel, Elmar Gocke, Malcolm G. P. Page, Jürg Dreier, Eva B Breitmaier

المصدر: Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 513:169-182

مصطلحات موضوعية: Chromatography, Fluorophore, Bacteria, Base Sequence, Mutagenicity Tests, Health, Toxicology and Mutagenesis, Molecular Sequence Data, Biology, medicine.disease_cause, Fluorescence, Genotoxicity testing, Toxicology, chemistry.chemical_compound, chemistry, Microsomes, Liver, Genetics, medicine, Promoter Regions, Genetic, SOS Response, Genetics, Genotoxicity, Glucuronidase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80d0daf316b8675f3f664b1bc491cd09
https://doi.org/10.1016/s1383-5718(01)00309-6

المؤلفون: Michel Dietz, Frederic Marlin, Raffaello Masciadri, David Banner, Christian M. Apfel, Henri Stalder, Christian Hubschwerlen, Daniel Bur, Hans Locher, Wolfgang Pirson

المصدر: Journal of Medicinal Chemistry. 44:1847-1852

مصطلحات موضوعية: Models, Molecular, Stereochemistry, Molecular Conformation, Microbial Sensitivity Tests, Crystallography, X-Ray, Hydroxamic Acids, Hydrazide, Aminopeptidases, Chemical synthesis, Amidohydrolases, chemistry.chemical_compound, Peptide deformylase, Drug Discovery, Escherichia coli, Humans, Protease Inhibitors, Antibacterial agent, Binding Sites, Hydroxamic acid, Bacteria, Thiadiazines, biology, Bicyclic molecule, Hydrogen Bonding, Anti-Bacterial Agents, chemistry, Enzyme inhibitor, Drug Design, Quinazolines, biology.protein, Molecular Medicine, Antibacterial activity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1651aa9f6e02995a81c4851b9c5f0e01
https://doi.org/10.1021/jm000352g

المؤلفون: Christian Hubschwerlen, Malcolm G. P. Page, Christian M. Apfel, Wolfgang Keck, Stefan Evers, Wolfgang Pirson

المصدر: Antimicrobial Agents and Chemotherapy. 45:1053-1057

مصطلحات موضوعية: Cell Extracts, Transcription, Genetic, Peptide, Microbial Sensitivity Tests, Biology, medicine.disease_cause, Aminopeptidases, Amidohydrolases, Peptide deformylase, chemistry.chemical_compound, Methionine, Bacterial Proteins, Escherichia coli, medicine, Pharmacology (medical), Enzyme Inhibitors, Mechanisms of Action: Physiological Effects, Antibacterial agent, Pharmacology, chemistry.chemical_classification, fungi, Biological activity, Anti-Bacterial Agents, body regions, Infectious Diseases, Enzyme, nervous system, Biochemistry, chemistry, Enzyme inhibitor, Protein Biosynthesis, biology.protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f88d8fb6c3be1ebc0f91edf186a20065
https://doi.org/10.1128/aac.45.4.1053-1057.2001

المؤلفون: Giuseppe Dastoli, Lucia Riccardi, Werner Bollag, P. Raffo, Laura Isnardi, Christian M. Apfel, Peter K. Lemotte, Salvatore Toma

المصدر: International Journal of Cancer. 78:86-94

مصطلحات موضوعية: Cancer Research, medicine.medical_specialty, medicine.drug_class, Antagonist, Retinoic acid, Cancer, Retinoid X receptor, Biology, medicine.disease, chemistry.chemical_compound, Endocrinology, Oncology, chemistry, Cell culture, Apoptosis, Internal medicine, Toxicity, medicine, Cancer research, Retinoid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fd79e56621206b96791ba4f0c1012626
https://doi.org/10.1002/(sici)1097-0215(19980925)78:1<86::aid-ijc14>3.0.co;2-3

المؤلفون: Markus Kamber, Peter Mohr, Siegfried Keidel, Peter K. Lemotte, Michael Klaus, Christian M. Apfel

المصدر: Journal of Biological Chemistry. 270:30765-30772

مصطلحات موضوعية: Transcriptional Activation, DNA, Complementary, Receptors, Retinoic Acid, medicine.drug_class, Retinoic acid, HL-60 Cells, Retinoid X receptor, Biology, Transfection, Binding, Competitive, Biochemistry, Retinoids, Structure-Activity Relationship, chemistry.chemical_compound, medicine, Humans, Retinoid, Receptor, Molecular Biology, Molecular Structure, Retinoid X receptor alpha, Retinoic Acid Receptor alpha, Antagonist, Cell Differentiation, Cell Biology, Retinoid X receptor gamma, Recombinant Proteins, Cell biology, body regions, Kinetics, Retinoid X Receptors, chemistry, embryonic structures, Retinoid X receptor beta, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f146a59bca5dc84ce9eeee72c9d4248
https://doi.org/10.1074/jbc.270.51.30765

المؤلفون: Christian M. Apfel, Hendrick Bothmann, Arnulf Dorn, Andreas Ebneth, Francis Hermann, Gerhard Trube, Klaus Christensen

المصدر: Journal of biomolecular screening. 10(4)

مصطلحات موضوعية: 0301 basic medicine, ERG1 Potassium Channel, Patch-Clamp Techniques, hERG, CHO Cells, Pharmacology, 01 natural sciences, Biochemistry, QT interval, Analytical Chemistry, 03 medical and health sciences, Cricetinae, Animals, Patch clamp, Fluorescent Dyes, biology, Drug discovery, Chemistry, Chinese hamster ovary cell, Reproducibility of Results, Potassium channel, Ether-A-Go-Go Potassium Channels, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 030104 developmental biology, Spectrometry, Fluorescence, Drug development, Potassium Channels, Voltage-Gated, biology.protein, Biophysics, Molecular Medicine, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe45e8cf59b4c7d3f0c4e38ba6976142
https://pubmed.ncbi.nlm.nih.gov/15964935

المؤلفون: Hans Locher, Christian M. Apfel, Stefan Evers, Christian Hubschwerlen, Bela Takacs, Wolfgang Keck, Malcolm G. P. Page, Wolfgang Pirson

المصدر: Antimicrobial agents and chemotherapy. 45(4)

مصطلحات موضوعية: Anti-Infective Agents, Urinary, Microbial Sensitivity Tests, Biology, medicine.disease_cause, Aminopeptidases, Trimethoprim, Microbiology, Amidohydrolases, Peptide deformylase, Bacterial Proteins, medicine, Escherichia coli, Pharmacology (medical), Enzyme Inhibitors, Mechanisms of Action: Physiological Effects, Antibacterial agent, Pharmacology, chemistry.chemical_classification, Biological activity, Drug Resistance, Microbial, Antimicrobial, Haemophilus influenzae, Anti-Bacterial Agents, Mutagenesis, Insertional, Infectious Diseases, Enzyme, Streptococcus pneumoniae, chemistry, Biochemistry, Enzyme inhibitor, Genes, Bacterial, Mutation, biology.protein, Transformation, Bacterial, Antibacterial activity, Drug Antagonism

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5bf3781855e779f41c46744d288a9ed
https://pubmed.ncbi.nlm.nih.gov/11257016

المؤلفون: Malcolm G. P. Page, Christian Hubschwerlen, David Banner, Christian M. Apfel, Daniel Bur, Gérard Rossé, Wolfgang Pirson, Jean-Luc Specklin, Hans Locher, Michel Dietz, Takahiro Hirata

المصدر: Journal of medicinal chemistry. 43(12)

مصطلحات موضوعية: Models, Molecular, Mycoplasma pneumoniae, medicine.disease_cause, Crystallography, X-Ray, Hydroxamic Acids, Aminopeptidases, Haemophilus influenzae, Microbiology, Amidohydrolases, Moraxella catarrhalis, chemistry.chemical_compound, Peptide deformylase, Structure-Activity Relationship, Drug Discovery, medicine, Escherichia coli, Protease Inhibitors, Enzyme Inhibitors, Moraxella, Respiratory Tract Infections, Antibacterial agent, Hydroxamic acid, biology, Chemistry, Drug Resistance, Microbial, Stereoisomerism, Chlamydophila pneumoniae, biology.organism_classification, Anti-Bacterial Agents, Biochemistry, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e97d92eeb6b132455bbecc68eadffa0
https://pubmed.ncbi.nlm.nih.gov/10882358

المؤلفون: Michael Fountoulakis, Martin Stieger, Christian M. Apfel, Bela Takacs, Wolfgang Keck

المصدر: Journal of bacteriology. 181(2)

مصطلحات موضوعية: Prenyltransferase, Saccharomyces cerevisiae, Molecular Sequence Data, Farnesyl pyrophosphate, Genetics and Molecular Biology, medicine.disease_cause, Microbiology, Chromatography, Affinity, chemistry.chemical_compound, Affinity chromatography, medicine, Escherichia coli, Animals, Amino Acid Sequence, Cloning, Molecular, Caenorhabditis elegans, Molecular Biology, Peptide sequence, Alkyl and Aryl Transferases, Molecular mass, biology, Bacteria, Sequence Homology, Amino Acid, Chromosome Mapping, Chromosomes, Bacterial, biology.organism_classification, Chromatography, Ion Exchange, Fusion protein, Molecular biology, Recombinant Proteins, Molecular Weight, Kinetics, chemistry, Biochemistry, Mutagenesis, Chromatography, Gel, Sequence Alignment

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ee7bea181cfa5f264e9f7051cd1a8a
https://pubmed.ncbi.nlm.nih.gov/9882662

المؤلفون: Christian M. Apfel, Siegfried Keidel, François Lamour

المصدر: The Journal of biological chemistry. 272(29)

مصطلحات موضوعية: Agonist, medicine.drug_class, Receptors, Retinoic Acid, Cellular differentiation, DNA Mutational Analysis, Retinoic acid, Tretinoin, Biology, Biochemistry, Benzoates, Polymerase Chain Reaction, chemistry.chemical_compound, Retinoids, medicine, Humans, Retinoid, Binding site, Chromans, Receptor, Molecular Biology, Alitretinoin, DNA Primers, Sequence Deletion, Binding Sites, Retinoic Acid Receptor alpha, Antagonist, Cell Biology, Peptide Fragments, Recombinant Proteins, Cell biology, Kinetics, Mutagenesis, Insertional, chemistry, Nuclear receptor, Mutagenesis, Site-Directed

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e771451b5a2d88e2c57877624364c4a
https://pubmed.ncbi.nlm.nih.gov/9218465

المؤلفون: Christian M. Apfel, François Lamour, P. Lardelli

المصدر: Molecular and cellular biology. 16(10)

مصطلحات موضوعية: Transcriptional Activation, Reticulocytes, Arginine, Transcription, Genetic, Receptors, Retinoic Acid, Molecular Sequence Data, Retinoic acid, Tretinoin, Biology, Ligands, Benzoates, chemistry.chemical_compound, Transactivation, Retinoids, Animals, Humans, Point Mutation, Amino Acid Sequence, Cysteine, Binding site, Chromans, Site-directed mutagenesis, Molecular Biology, chemistry.chemical_classification, Alanine, Binding Sites, Base Sequence, Sequence Homology, Amino Acid, Retinoic Acid Receptor alpha, Cell Biology, Molecular biology, Amino acid, Kinetics, chemistry, Biochemistry, Oligodeoxyribonucleotides, Retinoic acid receptor alpha, Protein Biosynthesis, Mutagenesis, Site-Directed, Rabbits, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99562d943d683471837b1ed5c4e13afd
https://pubmed.ncbi.nlm.nih.gov/8816450

المؤلفون: Siegfried Keidel, Peter K. Lemotte, Christian M. Apfel

المصدر: Biochimica et biophysica acta. 1289(2)

مصطلحات موضوعية: Stereochemistry, Receptors, Retinoic Acid, Biophysics, Retinoic acid, Retinoid X receptor, Ligands, Biochemistry, Retinoic acid-inducible orphan G protein-coupled receptor, chemistry.chemical_compound, Mice, Retinoids, Structure-Activity Relationship, Animals, Molecular Biology, Cell Nucleus, Retinoid X receptor alpha, Retinoid X receptor gamma, body regions, Retinoic acid receptor, Retinoid X Receptors, chemistry, Retinoic acid receptor alpha, embryonic structures, Retinoid X receptor beta, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71bf7c4e195d7938779496cd74671a81
https://pubmed.ncbi.nlm.nih.gov/8600988

المؤلفون: Christian M. Apfel, Siegfried Keidel, Peter K. Lemotte

المصدر: European journal of biochemistry. 236(1)

مصطلحات موضوعية: Transcriptional Activation, Phytanic acid, Receptors, Retinoic Acid, Molecular Sequence Data, Retinoic acid, Tretinoin, Retinoid X receptor, Ligands, Biochemistry, chemistry.chemical_compound, Alpha oxidation, medicine, Escherichia coli, Humans, Retinoid X receptor alpha, Base Sequence, Dose-Response Relationship, Drug, Peroxisome, medicine.disease, Recombinant Proteins, body regions, Phytanic Acid, Refsum disease, Retinoid X Receptors, Nuclear receptor, chemistry, embryonic structures, Refsum Disease, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fddc413b593a2c3ea4f69e825eefdd4a
https://pubmed.ncbi.nlm.nih.gov/8617282

المؤلفون: P LeMotte, W Pirson, Christian M. Apfel, M Kamber, M Crettaz, F Kaufmann, M Klaus, L Forni, F Bauer

المصدر: Proceedings of the National Academy of Sciences of the United States of America. 89(15)

مصطلحات موضوعية: Transcriptional Activation, Receptors, Retinoic Acid, Cellular differentiation, Retinoic acid, Tretinoin, Biology, Retinoid X receptor, Lymphocyte Activation, Transfection, Cell Line, chemistry.chemical_compound, Mice, Retinoids, Structure-Activity Relationship, medicine, Escherichia coli, Animals, Cloning, Molecular, Receptor, neoplasms, B-Lymphocytes, Multidisciplinary, Cell growth, organic chemicals, biological factors, Recombinant Proteins, Cell biology, body regions, DNA-Binding Proteins, Retinoic acid receptor, Kinetics, Biochemistry, chemistry, Receptors, Estrogen, Retinoic acid receptor alpha, embryonic structures, Carrier Proteins, medicine.drug, Plasmids, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ce359138ac3cd652d9ec6bf19995253
https://pubmed.ncbi.nlm.nih.gov/1323127

المؤلفون: Athanasios Denelavas, Roger G. Clerc, Franziska Weibel, Cornelia Hertel, Alexander Imbach, Christian M. Apfel, Michael Prummer

المصدر: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. (5):754-762

مصطلحات موضوعية: Time Factors, Myosin light-chain kinase, Calcium Channels, L-Type, Intracellular Space, Biology, Endocytosis, Heterocyclic Compounds, 4 or More Rings, Exocytosis, Cell Line, Imaging, Three-Dimensional, Calmodulin, Electric Impedance, Humans, Secretion, RNA, Small Interfering, Ouabain, Cell Shape, Molecular Biology, Actin, Voltage-dependent calcium channel, Angiotensin II, Vesicle, Impedance, BayK8644, Cell Biology, 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester, Cell biology, Membrane, Label-free technology, Adrenal Cortex, Thapsigargin, Calcium, Ca channel

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b68904ab683cf1b5a81e31d4b1fa62d6