المؤلفون: Florence Gross, Arturo Mancini, Billy Breton, Hiroyuki Kobayashi, Pedro Henrique Scarpelli Pereira, Christian Le Gouill, Michel Bouvier, Stephan Schann, Xavier Leroy, Laurent Sabbagh

المصدر: Communications Biology, Vol 7, Iss 1, Pp 1-16 (2024)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2399-3642

URL الوصول: https://doaj.org/article/0cc3d5d503574ee798e91bfae6c8edd3

المؤلفون: Shane C. Wright, Aikaterini Motso, Stefania Koutsilieri, Christian M. Beusch, Pierre Sabatier, Alessandro Berghella, Élodie Blondel-Tepaz, Kimberley Mangenot, Ioannis Pittarokoilis, Despoina-Christina Sismanoglou, Christian Le Gouill, Jesper V. Olsen, Roman A. Zubarev, Nevin A. Lambert, Alexander S. Hauser, Michel Bouvier, Volker M. Lauschke

المصدر: Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/87f6a5fc98af40a19909134b0c703db6

المؤلفون: Aliza T. Ehrlich, Meriem Semache, Pierre Couvineau, Stefan Wojcik, Hiroyuki Kobayashi, Marcus Thelen, Florence Gross, Mireille Hogue, Christian Le Gouill, Emmanuel Darcq, Michel Bouvier, Brigitte L. Kieffer

المصدر: Molecular Brain, Vol 14, Iss 1, Pp 1-23 (2021)

مصطلحات موضوعية: CXCR7, GPCR, Signaling, G protein, βarrestin, GABA, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1756-6606

URL الوصول: https://doaj.org/article/c691042905314379a42058d6da6d43ec

المؤلفون: Charlotte Avet, Arturo Mancini, Billy Breton, Christian Le Gouill, Alexander S Hauser, Claire Normand, Hiroyuki Kobayashi, Florence Gross, Mireille Hogue, Viktoriya Lukasheva, Stéphane St-Onge, Marilyn Carrier, Madeleine Héroux, Sandra Morissette, Eric B Fauman, Jean-Philippe Fortin, Stephan Schann, Xavier Leroy, David E Gloriam, Michel Bouvier

المصدر: eLife, Vol 11 (2022)

مصطلحات موضوعية: g protein-coupled receptor, enhanced bystander bioluminescence resonance energy transfer, effector membrane translocation assay, biosensor, G protein activation, high-throughput assay, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/74101; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/34e18aa1566b4e768be5932a0e81dff7

المؤلفون: Besma Benredjem, Jonathan Gallion, Dennis Pelletier, Paul Dallaire, Johanie Charbonneau, Darren Cawkill, Karim Nagi, Mark Gosink, Viktoryia Lukasheva, Stephen Jenkinson, Yong Ren, Christopher Somps, Brigitte Murat, Emma Van Der Westhuizen, Christian Le Gouill, Olivier Lichtarge, Anne Schmidt, Michel Bouvier, Graciela Pineyro

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/c0db3f1cf110426bbd5f35d40fd3681b

المؤلفون: Aliza T. Ehrlich, Meriem Semache, Florence Gross, Dillon F. Da Fonte, Leonie Runtz, Christine Colley, Amina Mezni, Christian Le Gouill, Viktoriya Lukasheva, Mireille Hogue, Emmanuel Darcq, Michel Bouvier, Brigitte L. Kieffer

المصدر: iScience, Vol 14, Iss , Pp 47-57 (2019)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S258900421930077X; https://doaj.org/toc/2589-0042

URL الوصول: https://doaj.org/article/88fbd700e88446eda04c7bc96f781810

المؤلفون: Anne-Marie Schönegge, Jonathan Gallion, Louis-Philippe Picard, Angela D. Wilkins, Christian Le Gouill, Martin Audet, Wayne Stallaert, Martin J. Lohse, Marek Kimmel, Olivier Lichtarge, Michel Bouvier

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/998b6cae615e45acb325e0d14982a595

المؤلفون: Yoon Namkung, Christian Le Gouill, Viktoria Lukashova, Hiroyuki Kobayashi, Mireille Hogue, Etienne Khoury, Mideum Song, Michel Bouvier, Stéphane A. Laporte

المصدر: Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/533dd58c08184acea1bdb815fa853d15

المؤلفون: Besma Benredjem, Jonathan Gallion, Dennis Pelletier, Paul Dallaire, Johanie Charbonneau, Darren Cawkill, Karim Nagi, Mark Gosink, Viktoryia Lukasheva, Stephen Jenkinson, Yong Ren, Christopher Somps, Brigitte Murat, Emma Van Der Westhuizen, Christian Le Gouill, Olivier Lichtarge, Anne Schmidt, Michel Bouvier, Graciela Pineyro

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/1f09235de66f4fc295108bc582f6d396

المؤلفون: Geneviève Lehoux, Christian Le Gouill, Jana Stankova, Marek Rola-pleszczynski

المصدر: Mediators of Inflammation, Vol 12, Iss 1, Pp 29-35 (2003)

مصطلحات موضوعية: Reactive oxygen species, Monocyte, Macrophage, c-fos, Chemotaxis., Pathology, RB1-214

وصف الملف: electronic resource

Relation: https://doaj.org/toc/0962-9351; https://doaj.org/toc/1466-1861

URL الوصول: https://doaj.org/article/fe0174f72ac646caa10c034a39fba055

المؤلفون: Bianca Plouffe (2517475), Angeliki Karamitri (435673), Tilman Flock (11999862), Jonathan M. Gallion (11999865), Shane Houston (11999868), Carole A. Daly (11999871), Amélie Bonnefond (11371193), Jean-Luc Guillaume (245573), Christian Le Gouill (11371187), Phillipe Froguel (11999874), Olivier Lichtarge (22747), Xavier Deupi (206453), Ralf Jockers (245630), Michel Bouvier (76074)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Neuroscience, Evolutionary Biology, Cancer, Mental Health, Infectious Diseases, Virology, negative matrix factorization, molecular features controlling, arrestin 2 recruitment, combined functional clustering, mutations differently impact, unique signaling features, z , i1 , 2 , gpcr functional selectivity, engage distinct subsets, functional selectivity, mtnr1b <, specific mutations, distinct domains, signaling signatures, signaling pathways, using non, structural modeling

Relation: https://figshare.com/articles/journal_contribution/Structural_Elements_Directing_G_Proteins_and_Arrestin_Interactions_with_the_Human_Melatonin_Type_2_Receptor_Revealed_by_Natural_Variants/19067580

الاتاحة: https://doi.org/10.1021/acsptsci.1c00239.s001

المؤلفون: Alan Hegron (11371181), Eunna Huh (4346086), Xavier Deupi (206453), Badr Sokrat (11371184), Wenwen Gao (2792551), Christian Le Gouill (11371187), Mickaël Canouil (11371190), Mathilde Boissel (5410769), Guillaume Charpentier (58252), Ronan Roussel (101806), Beverley Balkau (91114), Philippe Froguel (2247), Bianca Plouffe (2517475), Amélie Bonnefond (11371193), Olivier Lichtarge (22747), Ralf Jockers (245630), Michel Bouvier (76074)

مصطلحات موضوعية: Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Cancer, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, two g protein, structural elements involved, link functional selectivity, identify important regions, hormone mainly produced, domains differentially controlling, various signaling effectors, six nonsynonymous variants, severely defective variants, natural variants melatonin, 1 , natural variants, signaling profiles, mtnr1a <, like variants, selective defect, pineal gland, molecular mechanisms, molecular mechanism, large number, increasing number

Relation: https://figshare.com/articles/journal_contribution/Identification_of_Key_Regions_Mediating_Human_Melatonin_Type_1_Receptor_Functional_Selectivity_Revealed_by_Natural_Variants/16553402

الاتاحة: https://doi.org/10.1021/acsptsci.1c00157.s001

المؤلفون: Ahmed Mansour (1421014), Karim Nagi (11414276), Paul Dallaire (11414279), Viktoriya Lukasheva (11414282), Christian Le Gouill (11371187), Michel Bouvier (76074), Graciela Pineyro (11414285)

مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Neuroscience, Pharmacology, Immunology, Cancer, Science Policy, Infectious Diseases, protein kinase c, log ­( τ, cyclic adenosine monophosphate, classification process revealed, chronic pain syndromes, chronic pain management, cellular phenomenon contributes, βarr ), responses, tyrosyl )-( 3, carbonyl )- l, based signaling profiles, 5 )- enkephalin, dpdpe ), arm390, max , enhance camp production, clustering agonists according, 2 +

Relation: https://figshare.com/articles/journal_contribution/Comprehensive_Signaling_Profiles_Reveal_Unsuspected_Functional_Selectivity_of_Opioid_Receptor_Agonists_and_Allow_the_Identification_of_Ligands_with_the_Greatest_Potential_for_Inducing_Cyclase_Superactivation/16597871

الاتاحة: https://doi.org/10.1021/acsptsci.1c00019.s001

المؤلفون: Aliza T. Ehrlich (11497105), Meriem Semache (167963), Pierre Couvineau (4417000), Stefan Wojcik (11497108), Hiroyuki Kobayashi (148963), Marcus Thelen (164322), Florence Gross (11497111), Mireille Hogue (2488819), Christian Le Gouill (11371187), Emmanuel Darcq (741574), Michel Bouvier (76074), Brigitte L. Kieffer (9655861)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Cell Biology, Genetics, Molecular Biology, Neuroscience, Physiology, Pharmacology, Immunology, Mental Health, Infectious Diseases, CXCR7, GPCR, Signaling, G protein, βarrestin, GABA, Endothelial cells

Relation: https://figshare.com/articles/journal_contribution/Additional_file_1_of_Ackr3-Venus_knock-in_mouse_lights_up_brain_vasculature/16696540

الاتاحة: https://doi.org/10.6084/m9.figshare.16696540.v1

المؤلفون: Kévin Leguay, Omaima Naffati, Yu Yan He, Mireille Hogue, Chloé Tesnière, Elena Melania Gombos, Hellen Kuasne, Louis Gaboury, Christian Le Gouill, Sylvain Meloche, Michel Bouvier, Sébastien Carréno

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::802bfcb96683dbac37de656f89c084f9
https://doi.org/10.1101/2023.03.28.534587

المؤلفون: Bianca Plouffe, Angeliki Karamitri, Tilman Flock, Jonathan M. Gallion, Shane Houston, Carole A. Daly, Amélie Bonnefond, Jean-Luc Guillaume, Christian Le Gouill, Phillipe Froguel, Olivier Lichtarge, Xavier Deupi, Ralf Jockers, Michel Bouvier

المصدر: Plouffe, B, Karamitri, A, Flock, T, Gallion, J M, Houston, S, Daly, C A, Bonnefond, A, Guillaume, J-L, Le Gouill, C, Froguel, P, Lichtarge, O, Deupi, X, Jockers, R & Bouvier, M 2022, ' Structural elements directing G proteins and β-arrestin interactions with the human melatonin type 2 receptor revealed by natural variants ', ACS Pharmacology & Translational Science, vol. 5, no. 2, pp. 89-101 . https://doi.org/10.1021/acsptsci.1c00239

مصطلحات موضوعية: Pharmacology, Pharmacology (medical)

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a10e88db95d723db444f3c797d249364
https://doi.org/10.1021/acsptsci.1c00239

المؤلفون: Mohammad Amraei, Monique Lagacé, Jean-Michel Longpré, Viktoriya Lukasheva, Ryan D. Martin, Christian Le Gouill, Graciela Piñeyro, Dominic Devost, Yuji Shinjo, Stéphane A. Laporte, Junken Aoki, Billy Breton, Mireille Hogue, Michel Bouvier, Asuka Inoue, Yoon Namkung, Terence E. Hébert, Jason C. Tanny

المصدر: Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)

مصطلحات موضوعية: Cell type, Multidisciplinary, Gs alpha subunit, Chemistry, HEK 293 cells, lcsh:R, lcsh:Medicine, Cell biology, Signalling, Genome editing, Functional selectivity, lcsh:Q, Signal transduction, lcsh:Science, G protein-coupled receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1089637a764ec4169b322941b3c13d
http://link.springer.com/article/10.1038/s41598-020-65636-3

المؤلفون: Alexander S Hauser, Christian Le Gouill, Billy Breton, Arturo Mancini, Charlotte Avet, Claire Normand, Hiroyuki Kobayashi, Florence Gross, Mireille Hogue, Viktoriya Lukasheva, Stéphane St-Onge, Marilyn Carrier, Madeleine Héroux, Sandra Morissette, Eric B Fauman, Jean-Philippe Fortin, Stephan Schann, Xavier Leroy, David E Gloriam, Michel Bouvier

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5f84171dc34ed42eb23ad1e2ab56dc8a
https://doi.org/10.7554/elife.74101.sa2

المؤلفون: Stephen Jenkinson, Jonathan Gallion, Darren Cawkill, Brigitte Murat, Olivier Lichtarge, Yong Ren, Michel Bouvier, Karim Nagi, Emma T van der Westhuizen, Christian Le Gouill, Besma Benredjem, Viktoryia Lukasheva, Johanie Charbonneau, Paul Dallaire, Mark Gosink, Anne W. Schmidt, Christopher Somps, Dennis J. Pelletier, Graciela Piñeyro

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Signaling profiles, Computer science, Science, Guinea Pigs, Receptors, Opioid, mu, General Physics and Astronomy, Computational biology, Ligands, Bias signaling, General Biochemistry, Genetics and Molecular Biology, GPCRs, Clustering, Article, Receptors, G-Protein-Coupled, Food and drug administration, 03 medical and health sciences, 0302 clinical medicine, GTP-Binding Proteins, Animals, Cluster Analysis, Humans, Clinical responses, Cluster analysis, lcsh:Science, Author Correction, beta-Arrestins, G protein-coupled receptor, Pharmacology, Multidisciplinary, Ligand, Effector, General Chemistry, 3. Good health, Computational biology and bioinformatics, Analgesics, Opioid, 030104 developmental biology, HEK293 Cells, Drug screening, Classification methods, lcsh:Q, Receptors, Adrenergic, beta-2, Signal transduction, Unsupervised clustering, 030217 neurology & neurosurgery, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57762958730e340da6b5d5094174a386
https://doaj.org/article/c0db3f1cf110426bbd5f35d40fd3681b

المؤلفون: Mireille Hogue, Christian Le Gouill, Dillon F. Da Fonte, Meriem Semache, Viktoriya Lukasheva, Aliza T. Ehrlich, Leonie Runtz, Michel Bouvier, Emmanuel Darcq, Amina Mezni, Florence Gross, Brigitte L. Kieffer, Christine Colley

المساهمون: Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), McGill University = Université McGill [Montréal, Canada], Université de Montréal (UdeM), Douglas Hospital Research Center [Montreal, QC, Canada], University of Surrey (UNIS), univOAK, Archive ouverte

المصدر: iScience, Vol 14, Iss, Pp 47-57 (2019)
iScience
iScience, 2019, 14, pp.47-57. ⟨10.1016/j.isci.2019.03.011⟩

مصطلحات موضوعية: 0301 basic medicine, Drug, Cell signaling, Physiology, media_common.quotation_subject, Bioengineering, 02 engineering and technology, Biology, Article, 03 medical and health sciences, medicine, [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Receptor, lcsh:Science, Molecular Biology, media_common, G protein-coupled receptor, Multidisciplinary, Drug discovery, Cell Biology, Biological Sciences, 021001 nanoscience & nanotechnology, 3. Good health, 030104 developmental biology, Opioid, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], lcsh:Q, μ-opioid receptor, 0210 nano-technology, Neuroscience, Buprenorphine, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6b186b04fce0e647b51d23d5d1588f
http://www.sciencedirect.com/science/article/pii/S258900421930077X