المؤلفون: Cristina Díaz-Perlas, Benjamin Ricken, Lluc Farrera-Soler, Dmitrii Guschin, Florence Pojer, Kelvin Lau, Christian-Benedikt Gerhold, Christian Heinis

المصدر: Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/061fa9cf243f4870a024c34ddcd4e9e5

المؤلفون: Sevan Habeshian, Manuel Leonardo Merz, Gontran Sangouard, Ganesh Kumar Mothukuri, Mischa Schüttel, Zsolt Bognár, Cristina Díaz-Perlas, Jonathan Vesin, Julien Bortoli Chapalay, Gerardo Turcatti, Laura Cendron, Alessandro Angelini, Christian Heinis

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/210437f443a543c6824039c0096c7783

المؤلفون: Xu-Dong Kong, Christian Heinis

المصدر: CHIMIA, Vol 75, Iss 6, Pp 514-517 (2021)

مصطلحات موضوعية: combinatorial library, cyclic peptide, drug development, macrocycle, phage display, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.ingentaconnect.com/contentone/scs/chimia/2021/00000075/00000006/art00010; https://doaj.org/toc/0009-4293; https://doaj.org/toc/2673-2424

URL الوصول: https://doaj.org/article/a52d8b221ac14bfbb6f1831a21bbc5ef

المؤلفون: Jonas Wilbs, Xu-Dong Kong, Simon J. Middendorp, Raja Prince, Alida Cooke, Caitlin T. Demarest, Mai M. Abdelhafez, Kalliope Roberts, Nao Umei, Patrick Gonschorek, Christina Lamers, Kaycie Deyle, Robert Rieben, Keith E. Cook, Anne Angelillo-Scherrer, Christian Heinis

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/1f9ddb75be1e4a398c1ff63698dcaa1b

المؤلفون: Christian Heinis, Adela Calvente

المصدر: CHIMIA, Vol 75, Iss 4 (2021)

مصطلحات موضوعية: Chemical biology, Division of medicinal chemistry and chemical biology, Drug discovery, Life sciences switzerland, Ls2, Dmccb, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.chimia.ch/chimia/article/view/872; https://doaj.org/toc/0009-4293; https://doaj.org/toc/2673-2424

URL الوصول: https://doaj.org/article/d415879010e5460792c85e319489310e

المؤلفون: Alessandro Zorzi, Simon J. Middendorp, Jonas Wilbs, Kaycie Deyle, Christian Heinis

المصدر: Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/cb4c3effd8b24083a11b07d420333e2b

المؤلفون: Carolin von Schoultz, Christian Heinis, Yves Auberson

المصدر: CHIMIA, Vol 72, Iss 11 (2018)

مصطلحات موضوعية: Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.chimia.ch/chimia/article/view/1526; https://doaj.org/toc/0009-4293; https://doaj.org/toc/2673-2424

URL الوصول: https://doaj.org/article/4f2e20a29f23405d86ce33dff5832c4b

المؤلفون: Kaycie Deyle, Christian Heinis

المصدر: CHIMIA, Vol 72, Iss 6 (2018)

مصطلحات موضوعية: Cyclic peptide, Drug development, In vitro evolution, Peptide, Phage display, Protein epitope mimetics, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.chimia.ch/chimia/article/view/1456; https://doaj.org/toc/0009-4293; https://doaj.org/toc/2673-2424

URL الوصول: https://doaj.org/article/5bbcd6b7adeb4d05a73aab361cebc462

المؤلفون: Philippe Diderich, Christian Heinis

المصدر: CHIMIA, Vol 67, Iss 12 (2013)

مصطلحات موضوعية: Cyclic peptides, Directed evolution, Peptides, Phage display, Therapeutics, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.chimia.ch/chimia/article/view/5493; https://doaj.org/toc/0009-4293; https://doaj.org/toc/2673-2424

URL الوصول: https://doaj.org/article/52ea08e261284618b9001c2260b43033

المؤلفون: Inmaculada Rentero, Christian Heinis

المصدر: CHIMIA, Vol 65, Iss 11 (2011)

مصطلحات موضوعية: Antibody, Combinatorial library, Cyclic peptide, Directed evolution, Peptide, Phage display, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.chimia.ch/chimia/article/view/5114; https://doaj.org/toc/0009-4293; https://doaj.org/toc/2673-2424

URL الوصول: https://doaj.org/article/999e3c3c9bda436da4be87092c738de4

المؤلفون: Miwa Takahashi-Umebayashi, Kai Johnsson, Luc Reymond, Aurélien Roux, Robbie Loewith, Gerardo Turcatti, Christian Heinis, Stefan Matile, David Alonso Doval, Andreas Zumbuehl, Thomas Hannich, Ludovic Pineau, Howard Riezman

المصدر: CHIMIA, Vol 65, Iss 11 (2011)

مصطلحات موضوعية: Chemical biology, Fluorescent dyes, Giant unilamellar vesicles, Insulin receptor, Membranes, Microdomains, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.chimia.ch/chimia/article/view/5116; https://doaj.org/toc/0009-4293; https://doaj.org/toc/2673-2424

URL الوصول: https://doaj.org/article/daf1a112052a478eb1166e3e05e77f46

المؤلفون: Barbara Winter-Werner, Christian Heinis, Nicolai Cramer

المصدر: CHIMIA, Vol 65, Iss 10 (2011)

مصطلحات موضوعية: Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.chimia.ch/chimia/article/view/5109; https://doaj.org/toc/0009-4293; https://doaj.org/toc/2673-2424

URL الوصول: https://doaj.org/article/4c5a8961127b43a184f271e5ff011987

المؤلفون: Christian Heinis

المصدر: CHIMIA, Vol 65, Iss 9 (2011)

مصطلحات موضوعية: Combinatorial chemistry, Cyclic peptides, Encoded libraries, Peptide therapeutics, Phage display, Protease inhibitors, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.chimia.ch/chimia/article/view/5077; https://doaj.org/toc/0009-4293; https://doaj.org/toc/2673-2424

URL الوصول: https://doaj.org/article/2bcfee270803447cbdc6ca2e8bfc4600

المؤلفون: Sevan Habeshian (3622763), Ganesh A. Sable (11933968), Mischa Schüttel (1742674), Manuel L. Merz (11933971), Christian Heinis (1545412)

مصطلحات موضوعية: Biophysics, Biochemistry, Medicine, Biotechnology, Cancer, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, terminal thiol group, drug development , terminal disulfide linker, solid phase via, finally released via, method yields disulfide, cyclative release strategy, solid phase, intramolecular disulfide, cyclative mechanism, well plates, pure form, protecting groups, large numbers, exchange reaction, currently limited, chromatographic purification

Relation: https://figshare.com/articles/journal_contribution/Cyclative_Release_Strategy_to_Obtain_Pure_Cyclic_Peptides_Directly_from_the_Solid_Phase/18182581

الاتاحة: https://doi.org/10.1021/acschembio.1c00843.s001

المؤلفون: Vanessa Carle (9585964), Yuteng Wu (6311462), Rakesh Mukherjee (10782927), Xu-Dong Kong (1837174), Chloé Rogg (10782930), Quentin Laurent (4856143), Enza Cecere (10782933), Camille Villequey (10782936), Madhuree S. Konakalla (10782939), Tamara Maric (7176479), Christina Lamers (1373709), Cristina Díaz-Perlas (9585967), Kaycie Butler (9585970), Junko Goto (10782942), Bernd Stegmayr (8323518), Christian Heinis (1545412)

مصطلحات موضوعية: Biochemistry, Medicine, Molecular Biology, Pharmacology, Biotechnology, Developmental Biology, Hematology, Infectious Diseases, Chemical Sciences not elsewhere classified, Information Systems not elsewhere classified, anticoagulation drugs, Selective FXIa Inhibitors, cyclic peptide-based FXI inhibitor, anticoagulation effects, plasma half-life, anticoagulant effects, Cyclic Peptides, K i, animal blood, FXIa inhibition, Safe Anticoagulation Coagulation fa., anticoagulation therapy, IU, vivo hemodialysis model, PEGylated inhibitor, cyclic peptide inhibitor

Relation: https://figshare.com/articles/journal_contribution/Development_of_Selective_FXIa_Inhibitors_Based_on_Cyclic_Peptides_and_Their_Application_for_Safe_Anticoagulation/14573703

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c00056.s001

المؤلفون: Raphael J. Gübeli (10585262), Davide Bertoldo (2560555), Kenji Shimada (250482), Christian B. Gerhold (10585265), Verena Hurst (10585268), Yuichiro Takahashi (642065), Kai Harada (10585271), Ganesh K. Mothukuri (10585274), Jonas Wilbs (3681838), Masahiko Harata (31306), Susan M. Gasser (10585277), Christian Heinis (1545412)

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Immunology, Developmental Biology, Cancer, Inorganic Chemistry, Physical Sciences not elsewhere classified, Mimic Actin-Binding Protein Thymosi., example fluorophore-labeled probes, protein, G-actin peptides, actin subdomains 1, phage display library, competition binding experiments, F-actin, bicyclic peptide phalloidin, Evolved Peptides Bind Monomeric Actin

Relation: https://figshare.com/articles/journal_contribution/_i_In_Vitro_i_-Evolved_Peptides_Bind_Monomeric_Actin_and_Mimic_Actin-Binding_Protein_Thymosin-_4/14401739

الاتاحة: https://doi.org/10.1021/acschembio.0c00825.s001

المؤلفون: Xingyu Liu, Xinjian Ji, Christian Heinis, Jerome Waser

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b2f5d3f2c65572f594aafc4e8d983ce2
https://doi.org/10.26434/chemrxiv-2023-jskfd

المؤلفون: Christian Heinis, Stephan Kontos, Alessandro Angelini, Julia Morales-Sanfrutos, Sandeep Raghunathan, Lisa Pollaro

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b32accba96e2b4971705032cc1367d
https://doi.org/10.1158/1535-7163.22502892

المؤلفون: Gontran Sangouard, Alessandro Zorzi, Yuteng Wu, Edouard Ehret, Mischa Schüttel, Sangram Kale, Cristina Díaz‐Perlas, Jonathan Vesin, Julien Bortoli Chapalay, Gerardo Turcatti, Christian Heinis

المصدر: Angewandte Chemie International Edition. 60:21702-21707

مصطلحات موضوعية: Liquid transfer, Macrocyclic Compounds, Chemistry, Scale (chemistry), acoustic droplet ejection, droplet ejection, design, protein-protein interactions, Proto-Oncogene Proteins c-mdm2, Acoustics, General Medicine, General Chemistry, picomole scale, Combinatorial synthesis, Combinatorial chemistry, Catalysis, macrocycles, Reagent, Humans, Tumor Suppressor Protein p53, Acoustic droplet ejection, combinatorial synthesis, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::222b2b27ce24ac853e3a474392789136
https://doi.org/10.1002/anie.202107815

المؤلفون: Davide Bertoldo, Verena Hurst, Kai Harada, Kenji Shimada, Christian Heinis, Jonas Wilbs, Raphael J. Gübeli, Yuichiro Takahashi, Ganesh Kumar Mothukuri, Masahiko Harata, Susan M. Gasser, Christian B. Gerhold

المصدر: ACS Chemical Biology. 16:820-828

مصطلحات موضوعية: 0301 basic medicine, Phage display, biology, 010405 organic chemistry, Chemistry, Phalloidin, macromolecular substances, General Medicine, Plasma protein binding, 01 natural sciences, Biochemistry, 0104 chemical sciences, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, Protein structure, biology.protein, Molecular Medicine, Actin-binding protein, Binding site, Peptide library, Actin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d4145d4f31db081f1ab4373606e889e0
https://doi.org/10.1021/acschembio.0c00825