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1Academic Journal
المؤلفون: Mohammed Amir, Sweena Chaudhari, Ran Wang, Sean Campbell, Sarah A. Mosure, Laura B. Chopp, Qun Lu, Jinsai Shang, Oliver B. Pelletier, Yuanjun He, Christelle Doebelin, Michael D. Cameron, Douglas J. Kojetin, Theodore M. Kamenecka, Laura A. Solt
المصدر: Cell Reports, Vol 25, Iss 13, Pp 3733-3749.e8 (2018)
مصطلحات موضوعية: Biology (General), QH301-705.5
وصف الملف: electronic resource
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2Academic Journal
المؤلفون: Jing Zhao, Lei Zhang, Xiaodong Mu, Christelle Doebelin, William Nguyen, Callen Wallace, Daniel P Reay, Sara J McGowan, Lana Corbo, Paula R Clemens, Gabriela Mustata Wilson, Simon C Watkins, Laura A Solt, Michael D Cameron, Johnny Huard, Laura J Niedernhofer, Theodore M Kamenecka, Paul D Robbins
المصدر: PLoS Biology, Vol 16, Iss 6, p e2004663 (2018)
مصطلحات موضوعية: Biology (General), QH301-705.5
وصف الملف: electronic resource
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3
المؤلفون: Timothy S. Strutzenberg, Ruben D. Garcia-Ordonez, Dean P. Edwards, Theodore M. Kamenecka, Mi Ra Chang, Patrick R. Griffin, Scott J. Novick, Christelle Doebelin, Yuanjun He, Yingmin Zhu
المصدر: J Mol Biol
مصطلحات موضوعية: Protein Conformation, Response element, Response Elements, Mass Spectrometry, Article, Nuclear Receptor Coactivator 3, X-Ray Diffraction, Structural Biology, RAR-related orphan receptor gamma, Scattering, Small Angle, Animals, Humans, Molecular Biology, Transcription factor, Orphan receptor, Mice, Inbred BALB C, Binding Sites, Chemistry, DNA-binding domain, DNA, Nuclear Receptor Subfamily 1, Group F, Member 3, Ligand (biochemistry), Cell biology, Crosstalk (biology), Nuclear receptor, Gene Expression Regulation, Female
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4
المؤلفون: Theodore M. Kamenecka, Angelo Blasio, Simone M. Giovanetti, Michael D. Cameron, Robert O. Messing, Matthew B. Pomrenze, Jingyi Wang, Christelle Doebelin, Jon Lindstrom, Holly L. Chapman, Victor Liaw, Alexander Kuryatov, Li Lin
المصدر: Neuropsychopharmacology
مصطلحات موضوعية: Male, Allosteric modulator, Alcohol Drinking, Pyridines, medicine.medical_treatment, Self Administration, Pharmacology, Receptors, Nicotinic, Partial agonist, Article, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Medicine, Animals, Nicotinic Agonists, Varenicline, Saccharin, Oxadiazoles, Dose-Response Relationship, Drug, Ethanol, business.industry, 030227 psychiatry, Mice, Inbred C57BL, Psychiatry and Mental health, Nicotinic agonist, chemistry, Mice, Inbred DBA, Cholinergic, Smoking cessation, Drug Therapy, Combination, Female, business, Self-administration, 030217 neurology & neurosurgery
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5
المؤلفون: Michael D. Cameron, Theodore M. Kamenecka, Ruben D. Garcia-Ordonez, Venkatasubramanian Dharmarajan, Mi Ra Chang, Li Lin, Christelle Doebelin, Dana S. Kuruvilla, Rémi Patouret, Scott J. Novick, Patrick R. Griffin
المصدر: ChemMedChem. 11:2607-2620
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, Regulator, Retinoic acid, 01 natural sciences, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, Cancer immunotherapy, Drug Discovery, medicine, Inverse agonist, General Pharmacology, Toxicology and Pharmaceutics, Pharmacology, Orphan receptor, 010405 organic chemistry, Cell growth, Chemistry, Organic Chemistry, 0104 chemical sciences, Cell biology, Retinoic acid receptor, 030104 developmental biology, Nuclear receptor, Molecular Medicine
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6
المؤلفون: Abba E. Leffler, Jingyi Wang, Theodore M. Kamenecka, Alexander Kuryatov, Jon Lindstrom, Christelle Doebelin, Jack Norleans
المصدر: J Biol Chem
مصطلحات موضوعية: 0301 basic medicine, Agonist, Allosteric modulator, Patch-Clamp Techniques, medicine.drug_class, Allosteric regulation, Thiophenes, Receptors, Nicotinic, Biochemistry, 03 medical and health sciences, Xenopus laevis, Allosteric Regulation, Piperidines, medicine, Animals, Humans, Amino Acid Sequence, Nicotinic Agonists, Binding site, Molecular Biology, Binding Sites, 030102 biochemistry & molecular biology, Chemistry, Long-term potentiation, Cell Biology, Recombinant Proteins, Cell biology, Protein Structure, Tertiary, Molecular Docking Simulation, Transmembrane domain, Nicotinic acetylcholine receptor, Kinetics, Protein Subunits, 030104 developmental biology, Docking (molecular), Mutagenesis, Site-Directed, Oocytes, Sequence Alignment, Molecular Biophysics
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7
المؤلفون: Michael D. Cameron, William R. Roush, Laura A. Solt, Theodore M. Kamenecka, Marcel Koenig, Susan Kahn, Sean Campbell, Li Lin, Ruben D. Garcia-Ordonez, Mi Ra Chang, Philippe Nuhant, Naresh Kumar, Yuanjun He, Christelle Doebelin, Patrick R. Griffin
المصدر: Medicinal chemistry (Shariqah (United Arab Emirates)). 15(6)
مصطلحات موضوعية: Agonist, Drug Inverse Agonism, Hydrocarbons, Fluorinated, medicine.drug_class, Pharmacology, Ligands, 01 natural sciences, 03 medical and health sciences, Mice, Structure-Activity Relationship, In vivo, Drug Discovery, medicine, Inverse agonist, Animals, Humans, Liver X receptor, 030304 developmental biology, Liver X Receptors, Orphan receptor, 0303 health sciences, Sulfonamides, Molecular Structure, Chemistry, Nuclear Receptor Subfamily 1, Group F, Member 1, Nuclear Receptor Subfamily 1, Group F, Member 3, In vitro, 0104 chemical sciences, Rats, 010404 medicinal & biomolecular chemistry, Retinoic acid receptor, Nuclear receptor, Th17 Cells
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8
المؤلفون: Scott J. Novick, Ruben D. Garcia-Ordonez, Mi Ra Chang, Venkatasubramanian Dharmarajan, Sean Campbell, Rémi Patouret, Anthony Ciesla, Theodore M. Kamenecka, Laura A. Solt, Patrick R. Griffin, Christelle Doebelin
المصدر: Bioorganicmedicinal chemistry letters. 28(19)
مصطلحات موضوعية: 0301 basic medicine, Scaffold, Clinical Biochemistry, Pharmaceutical Science, Thiophenes, Biochemistry, Mass Spectrometry, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Aminothiazole, In vivo, Drug Discovery, Inverse agonist, Humans, Receptor, Molecular Biology, Chemistry, Organic Chemistry, Nuclear Receptor Subfamily 1, Group F, Member 2, In vitro, Cell biology, 030104 developmental biology, Nuclear receptor, 030220 oncology & carcinogenesis, Molecular Medicine, Function (biology)
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9
المؤلفون: Lana Corbo, Michael D. Cameron, Lei Zhang, Johnny Huard, Sara J. McGowan, Xiaodong Mu, Jing Zhao, William Nguyen, Daniel P. Reay, Callen T. Wallace, Paul D. Robbins, Gabriela Mustata Wilson, Paula R. Clemens, Theodore M. Kamenecka, Simon C. Watkins, Laura A. Solt, Christelle Doebelin, Laura J. Niedernhofer
المصدر: PLoS Biology, Vol 16, Iss 6, p e2004663 (2018)
PLoS Biologyمصطلحات موضوعية: Lipopolysaccharides, 0301 basic medicine, Physiology, Electrophoretic Mobility Shift Assay, IκB kinase, Restriction Fragment Mapping, Pathology and Laboratory Medicine, Biochemistry, Mice, 0302 clinical medicine, Biomimetic Materials, Immune Physiology, Medicine and Health Sciences, Group-Specific Staining, Biology (General), Immune Response, Staining, Innate Immune System, Organic Compounds, General Neuroscience, Animal Models, Acquired immune system, I-kappa B Kinase, Enzymes, Cell biology, Chemistry, Experimental Organism Systems, Physical Sciences, Cytokines, Female, medicine.symptom, Oxidoreductases, General Agricultural and Biological Sciences, Luciferase, Research Article, Biotechnology, Binding domain, QH301-705.5, Immunology, Mouse Models, Inflammation, Biology, Research and Analysis Methods, General Biochemistry, Genetics and Molecular Biology, Cell Line, Necrosis, 03 medical and health sciences, Model Organisms, Signs and Symptoms, Protein Domains, Diagnostic Medicine, medicine, Animals, Humans, Electrophoretic mobility shift assay, Molecular Biology Techniques, Protein Interactions, Molecular Biology, Transcription factor, General Immunology and Microbiology, Tumor Necrosis Factor-alpha, Organic Chemistry, Gene Mapping, Hematoxylin Staining, HEK 293 cells, Chemical Compounds, Biology and Life Sciences, Proteins, Pneumonia, Molecular Development, Mice, Inbred C57BL, Muscular Dystrophy, Duchenne, HEK293 Cells, RAW 264.7 Cells, 030104 developmental biology, Small Molecules, Specimen Preparation and Treatment, Apoptosis, Immune System, Enzymology, 030217 neurology & neurosurgery, Developmental Biology
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10
المؤلفون: Ruben D. Garcia-Ordonez, Dana S. Kuruvilla, Mi Ra Chang, Christelle Doebelin, Theodore M. Kamenecka, Venkatasubramanian Dharmarajan, Patrick R. Griffin, Scott J. Novick
المصدر: ACS Chemical Biology. 11:1012-1018
مصطلحات موضوعية: 0301 basic medicine, T cell, Population, chemical and pharmacologic phenomena, Biology, Biochemistry, Article, 03 medical and health sciences, 0302 clinical medicine, Immune system, RAR-related orphan receptor gamma, Immunity, medicine, Humans, education, Transcription factor, Cell Proliferation, Immunity, Cellular, education.field_of_study, Cell growth, General Medicine, Nuclear Receptor Subfamily 1, Group F, Member 3, Immune checkpoint, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Immunology, Cancer research, Molecular Medicine
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11
المؤلفون: Theodore M. Kamenecka, Yuanjun He, Christelle Doebelin
المصدر: Tetrahedron Letters. 57:5658-5660
مصطلحات موضوعية: 010405 organic chemistry, Organic Chemistry, 010402 general chemistry, Hydrazide, 01 natural sciences, Biochemistry, Article, Chiral resolution, 0104 chemical sciences, law.invention, chemistry.chemical_compound, Enantiopure drug, chemistry, law, Yield (chemistry), Drug Discovery, Organic chemistry, Crystallization, Enantiomer
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12
المؤلفون: Michael D. Cameron, Theodore M. Kamenecka, Ruben D. Garcia-Ordonez, Rémi Patouret, Patrick R. Griffin, Mi Ra Chang, Christelle Doebelin, Claudia Ruiz
المصدر: Bioorganicmedicinal chemistry letters. 28(7)
مصطلحات موضوعية: 0301 basic medicine, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Article, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, 0302 clinical medicine, Aminothiazole, Drug Discovery, Inverse agonist, Molecule, Humans, Molecular Biology, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Organic Chemistry, Nuclear Receptor Subfamily 1, Group F, Member 2, Combinatorial chemistry, Small molecule, Thiazoles, 030104 developmental biology, Nuclear receptor, 030220 oncology & carcinogenesis, Molecular Medicine
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13
المؤلفون: Frédéric Bihel, Martine Schmitt, Christophe Salomé, Christelle Doebelin, Maud Bollenbach, Patrick Wagner, Jean-Jacques Bourguignon
المصدر: Green Chem.. 16:4170-4178
مصطلحات موضوعية: Coupling (electronics), chemistry.chemical_compound, Aqueous solution, chemistry, Ligand, Rapid access, Environmental Chemistry, Organic chemistry, Organic synthesis, Pollution, Catalysis
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14
المؤلفون: Christelle Doebelin, Frédéric Simonin, Frédéric Bihel, Isabelle Bertin, Séverine Schneider, Caroline Ancel, Martine Schmitt, Valérie Simonneaux, Jean-Jacques Bourguignon
المساهمون: Laboratoire d'Innovation Thérapeutique (LIT), Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut de Chimie du CNRS (INC), Génétique Diversité et Ecophysiologie des Céréales (GDEC), Institut National de la Recherche Agronomique (INRA)-Université Blaise Pascal - Clermont-Ferrand 2 (UBP), Institut des Neurosciences Cellulaires et Intégratives (INCI), Université de Strasbourg (UNISTRA)-Centre National de la Recherche Scientifique (CNRS), Université Louis Pasteur - Strasbourg I-Centre National de la Recherche Scientifique (CNRS), Institut de génétique et biologie moléculaire et cellulaire (IGBMC), Université Louis Pasteur - Strasbourg I-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Université de Strasbourg (UNISTRA)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS)
المصدر: ChemMedChem
ChemMedChem, Wiley-VCH Verlag, 2016, 11 (19), pp.2147-2154. ⟨10.1002/cmdc.201600331⟩
ChemMedChem, 2016, 11 (19), pp.2147-2154. ⟨10.1002/cmdc.201600331⟩مصطلحات موضوعية: Male, 0301 basic medicine, chemistry, metabolism, Stereochemistry, [SDV]Life Sciences [q-bio], Sonogashira coupling, Neuropeptide, Peptide, Endogeny, Biochemistry, Receptors, G-Protein-Coupled, Mice, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Kisspeptin, Drug Discovery, Animals, Humans, [CHIM]Chemical Sciences, Testosterone, General Pharmacology, Toxicology and Pharmaceutics, ComputingMilieux_MISCELLANEOUS, Pharmacology, chemistry.chemical_classification, Dipeptide, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Organic Chemistry, Dipeptides, Affinities, Rats, 3. Good health, 030104 developmental biology, Microsomes, Liver, Molecular Medicine, agonists, Sciences du Vivant [q-bio]/Neurosciences [q-bio.NC], pharmacology, Chimie/Chimie thérapeutique, biosynthesis, 030217 neurology & neurosurgery, Receptors, Kisspeptin-1
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15
المؤلفون: Marie Niederst, François Hallé, Olivier Van der Poorten, Steven Ballet, Frédéric Bihel, Christelle Doebelin, Martine Schmitt, Séverine Schneider
المصدر: ChemInform. 47
مصطلحات موضوعية: chemistry.chemical_compound, Enantiopure drug, Organic base, Chemistry, XPhos, Intramolecular force, Intramolecular cyclization, Regioselectivity, chemistry.chemical_element, General Medicine, Combinatorial chemistry, Catalysis, Palladium
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16
المؤلفون: Frédéric Bihel, Martine Schmitt, Marie Niederst, Séverine Schneider, Christelle Doebelin, François Hallé, Olivier Van der Poorten, Steven Ballet
المساهمون: Acides Nucléiques : Régulations Naturelle et Artificielle (ARNA), Université de Bordeaux (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Innovation Thérapeutique (LIT), Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut de Chimie du CNRS (INC), Rétrovirus et Maladies Associées, Institut National de la Santé et de la Recherche Médicale (INSERM)
المصدر: Tetrahedron Letters
Tetrahedron Letters, Elsevier, 2016, 57 (14), pp.1547-1550. ⟨10.1016/j.tetlet.2016.02.094⟩مصطلحات موضوعية: Organic base, 010405 organic chemistry, Chemistry, [CHIM.ORGA]Chemical Sciences/Organic chemistry, Organic Chemistry, Intramolecular cyclization, Regioselectivity, chemistry.chemical_element, 010402 general chemistry, 01 natural sciences, Biochemistry, Combinatorial chemistry, 0104 chemical sciences, Catalysis, chemistry.chemical_compound, Enantiopure drug, XPhos, Intramolecular force, Drug Discovery, [CHIM]Chemical Sciences, ComputingMilieux_MISCELLANEOUS, Palladium
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17
المؤلفون: Séverine Schneider, Laurent Roumeas, Christelle Doebelin, Jean-Jacques Bourguignon, Martine Schmitt, Jean-Paul Humbert, Frédéric Bihel, Frédéric Simonin, Isabelle Bertin
المساهمون: Laboratoire d'Innovation Thérapeutique (LIT), Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut de Chimie du CNRS (INC), Biotechnologie et signalisation cellulaire (BSC), Université de Strasbourg (UNISTRA)-Institut de recherche de l'Ecole de biotechnologie de Strasbourg (IREBS)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Peptides
Peptides, Elsevier, 2015, 71, pp.156-161. ⟨10.1016/j.peptides.2015.07.016⟩مصطلحات موضوعية: Agonist, Receptors, Neuropeptide, [SDV.BIO]Life Sciences [q-bio]/Biotechnology, Physiology, medicine.drug_class, Neuropeptides, Antagonist, Neuropeptide, Endogeny, Biology, Biochemistry, Receptors, G-Protein-Coupled, N-terminus, Cellular and Molecular Neuroscience, Endocrinology, Kisspeptins, medicine, Humans, Amino Acid Sequence, Receptor, hormones, hormone substitutes, and hormone antagonists, G protein-coupled receptor, Receptors, Kisspeptin-1, Sequence Deletion
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18
المؤلفون: Oliver B. Pelletier, Michael D. Cameron, Laura B. Chopp, Douglas J. Kojetin, Sarah A. Mosure, Mohammed Amir, Sweena M. Chaudhari, Christelle Doebelin, Sean Campbell, Ran Wang, Jinsai Shang, Theodore M. Kamenecka, Qun Lu, Yuanjun He, Laura A. Solt
المصدر: Cell reports
Cell Reports, Vol 25, Iss 13, Pp 3733-3749.e8 (2018)مصطلحات موضوعية: 0301 basic medicine, Male, Encephalomyelitis, Autoimmune, Experimental, Alpha (ethology), Autoimmunity, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, RAR-related orphan receptor gamma, medicine, Animals, Humans, lcsh:QH301-705.5, Psychological repression, Transcription factor, Inflammation, Cell growth, Chemistry, Experimental autoimmune encephalomyelitis, Nuclear Receptor Subfamily 1, Group F, Member 3, medicine.disease, Colitis, Phenotype, 3. Good health, Up-Regulation, Mice, Inbred C57BL, 030104 developmental biology, HEK293 Cells, lcsh:Biology (General), Nuclear Receptor Subfamily 1, Group D, Member 1, Cancer research, Disease Progression, Th17 Cells, Female
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19
المؤلفون: Frédéric Bihel, Patrick Wagner, Martine Schmitt, Christophe Salomé, Christelle Doebelin, Jean-Jacques Bourguignon, Maud Bollenbach
المصدر: ChemInform. 46
مصطلحات موضوعية: Coupling (electronics), chemistry.chemical_compound, Chemistry, Computational chemistry, Ligand, Aryl, High activity, Halide, General Medicine
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20
المؤلفون: Martine Schmitt, Cyril Assongo Kenfack, Frédéric Bihel, Jean-Jacques Bourguignon, Nicolas Humbert, Patrick Wagner, Yves Mély, Christelle Doebelin
المصدر: ChemInform. 45
مصطلحات موضوعية: chemistry.chemical_compound, Bearing (mechanical), Chemistry, law, Pyridine, Halogenation, Organic chemistry, General Medicine, law.invention