المؤلفون: Ghazaleh Eskandari-Sedighi, Madeline Crichton, Sameera Zia, Erik Gomez-Cardona, Leonardo M. Cortez, Zain H. Patel, Kei Takahashi-Yamashiro, Chris D. St. Laurent, Gaurav Sidhu, Susmita Sarkar, Vivian Aghanya, Valerie L. Sim, Qiumin Tan, Olivier Julien, Jason R. Plemel, Matthew S. Macauley

المصدر: Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-27 (2024)

مصطلحات موضوعية: Alzheimer’s disease, CD33, Microglia, Plaque compaction, Siglec, Amyloid-beta, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1750-1326

URL الوصول: https://doaj.org/article/e2bd71e630ca42e2903e16f780fc40b0

المؤلفون: Cristina Di Carluccio, Linda Cerofolini, Miguel Moreira, Frédéric Rosu, Luis Padilla-Cortés, Giulia Roxana Gheorghita, Zhuojia Xu, Abhishek Santra, Hai Yu, Shinji Yokoyama, Taylor E. Gray, Chris D. St. Laurent, Yoshiyuki Manabe, Xi Chen, Koichi Fukase, Matthew S. Macauley, Antonio Molinaro, Tiehai Li, Barbara A. Bensing, Roberta Marchetti, Valérie Gabelica, Marco Fragai, Alba Silipo

المصدر: ACS Central Science, Vol 10, Iss 2, Pp 447-459 (2024)

مصطلحات موضوعية: Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2374-7951

URL الوصول: https://doaj.org/article/f888054ea1c443f9aeac1a296ab0f10a

المؤلفون: Abhishek Bhattacherjee, Jaesoo Jung, Sameera Zia, Madelene Ho, Ghazaleh Eskandari-Sedighi, Chris D. St. Laurent, Kelli A. McCord, Arjun Bains, Gaurav Sidhu, Susmita Sarkar, Jason R. Plemel, Matthew S. Macauley

المصدر: Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-22 (2021)

مصطلحات موضوعية: Alzheimer’s disease, CD33, Immunomodulatory, Isoform, Microglia, Phagocytosis, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1750-1326

URL الوصول: https://doaj.org/article/9d903e7fcaaf46188f4b75d343f185d2

المؤلفون: Emily Rodrigues, Jaesoo Jung, Heajin Park, Caleb Loo, Sepideh Soukhtehzari, Elena N. Kitova, Fahima Mozaneh, Gour Daskhan, Edward N. Schmidt, Vivian Aghanya, Susmita Sarkar, Laura Streith, Chris D. St. Laurent, Linh Nguyen, Jean-Philippe Julien, Lori J. West, Karla C. Williams, John S. Klassen, Matthew S. Macauley

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/c0a8a14897d44e9db090036236f8b1ee

المؤلفون: Cristina Di Carluccio, Linda Cerofolini, Miguel Moreira, Frédéric Rosu, Luis Padilla-Cortés, Giulia Roxana Gheorghita, Zhuojia Xu, Abhishek Santra, Hai Yu, Shinji Yokoyama, Taylor E. Gray, Chris D. St. Laurent, Yoshiyuki Manabe, Xi Chen, Koichi Fukase, Matthew S. Macauley, Antonio Molinaro, Tiehai Li, Barbara A. Bensing, Roberta Marchetti, Valérie Gabelica, Marco Fragai, Alba Silipo

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Genetics, Cancer, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, positive bacterial species, native mass spectrometry, isothermal titration calorimetry, including flow cytometry, gordonii ub10712 possesses, disialylated core 2, also cause local, main binding site, like binding regions, human oral cavity, >- glycan structures, oral colonization, human salivary, binding preferences, binding pocket, >- glycans, >- glycan, wide range, typically colonizes, systemic diseases, streptococcal infections, sta branch

Relation: https://figshare.com/articles/journal_contribution/Molecular_Insights_into_O_Linked_Sialoglycans_Recognition_by_the_Siglec-Like_SLBR_N_SLBR_sub_UB10712_sub_of_Streptococcus_gordonii/25164900

الاتاحة: https://doi.org/10.1021/acscentsci.3c01598.s003
https://figshare.com/articles/journal_contribution/Molecular_Insights_into_O_Linked_Sialoglycans_Recognition_by_the_Siglec-Like_SLBR_N_SLBR_sub_UB10712_sub_of_Streptococcus_gordonii/25164900

المؤلفون: Jaesoo Jung (9466023), Jhon R. Enterina (11575844), Duong T. Bui (10197574), Fahima Mozaneh (11575847), Po-Han Lin (2367535), Nitin (11575850), Chu-Wei Kuo (1507567), Emily Rodrigues (8416182), Abhishek Bhattacherjee (581982), Parisa Raeisimakiani (11575853), Gour C. Daskhan (11575856), Chris D. St. Laurent (10454519), Kay-Hooi Khoo (341338), Lara K. Mahal (741852), Wesley F. Zandberg (2291527), Xuefei Huang (1261959), John S. Klassen (622871), Matthew S. Macauley (2318164)

مصطلحات موضوعية: Biophysics, Biochemistry, Microbiology, Cell Biology, Pharmacology, Biotechnology, Cancer, Environmental Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, tuning siglec ligands, sodium chlorate sensitivity, poorer survival rates, highly homogeneous siglec, affinity (≥ 28, five cell lines, determine ≥ 8, diminish siglec binding, based binding assay, fold enhanced affinity, emerging evidence suggesting, cells greatly enhanced, cell type dependent, cancer cell lines, ≥ 2, sulfated glycans, specific pattern, pharmacological blockade, numerous cancers, new mode, immunomodulatory family

Relation: https://figshare.com/articles/journal_contribution/Carbohydrate_Sulfation_As_a_Mechanism_for_Fine-Tuning_Siglec_Ligands/16825853

الاتاحة: https://doi.org/10.1021/acschembio.1c00501.s001

المؤلفون: Abhishek Bhattacherjee (581982), Jaesoo Jung (9466023), Sameera Zia (10454513), Madelene Ho (10454516), Ghazaleh Eskandari-Sedighi (4493020), Chris D. St. Laurent (10454519), Kelli A. McCord (10454522), Arjun Bains (10454525), Gaurav Sidhu (10454528), Susmita Sarkar (332225), Jason R. Plemel (10454531), Matthew S. Macauley (10454534)

مصطلحات موضوعية: Genetics, Alzheimer’s disease, CD33, Immunomodulatory, Isoform, Microglia, Phagocytosis, Mouse model, Gain-of-function

Relation: https://figshare.com/articles/journal_contribution/Additional_file_1_of_The_CD33_short_isoform_is_a_gain-of-function_variant_that_enhances_A_1_42_phagocytosis_in_microglia/14314649

الاتاحة: https://doi.org/10.6084/m9.figshare.14314649.v1

المؤلفون: Matthew D. Benson, MD, Kimberly M. Papp, BSc, Geoffrey A. Casey, BSc(EE), BSc(MolBiol), Alina Radziwon, BSc, Chris D. St Laurent, BSc, Lance P. Doucette, PhD, Ian M. MacDonald, MD, CM

المصدر: Ophthalmology Science, Vol 1, Iss 2, Pp 100028- (2021)

مصطلحات موضوعية: Hearing loss, Peroxisomal biogenesis disorders, Peroxisome, PEX6, Retinal degeneration, Usher syndrome, Ophthalmology, RE1-994

Relation: http://www.sciencedirect.com/science/article/pii/S2666914521000269; https://doaj.org/toc/2666-9145; https://doaj.org/article/53a69df201ae4fe7b07ce21f724d1d22

الاتاحة: https://doi.org/10.1016/j.xops.2021.100028
https://doaj.org/article/53a69df201ae4fe7b07ce21f724d1d22

المؤلفون: Hansol Park, Eiman A. Osman, Christopher R. Cromwell, Chris D. St Laurent, Yuning Liu, Elena N. Kitova, John S. Klassen, Basil P. Hubbard, Matthew S. Macauley, Julianne M. Gibbs

المصدر: Bioconjugate Chemistry. 33:858-868

مصطلحات موضوعية: Gene Editing, Pharmacology, Azides, Alkynes, Organic Chemistry, Biomedical Engineering, Pharmaceutical Science, Bioengineering, CRISPR-Cas Systems, RNA, Guide, Kinetoplastida, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e87a055248ac42594d1066a86e1361
https://doi.org/10.1021/acs.bioconjchem.2c00106

المؤلفون: Santiago Tijaro Bulla, Eiman A. Osman, Chris D. St Laurent, Matthew S. Macauley, Julianne M. Gibbs

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9bb42ba181fec211de747cc38ae91613
https://doi.org/10.26434/chemrxiv-2023-qhhkz

المؤلفون: Jhon R. Enterina, Matthew S. Macauley, Chris D. St. Laurent, Kay-Hooi Khoo, Abhishek Bhattacherjee, Chu-Wei Kuo, Wesley F. Zandberg, Fahima Mozaneh, Emily Rodrigues, Parisa Raeisimakiani, Gour Chand Daskhan, Jaesoo Jung, H Nitin, Po-Han Lin, Xuefei Huang, Lara K. Mahal, Duong T Bui, John S. Klassen

المصدر: ACS Chemical Biology. 16:2673-2689

مصطلحات موضوعية: Glycan, CD33, Down-Regulation, Context (language use), Ligands, Biochemistry, Mass Spectrometry, Cell Line, 03 medical and health sciences, 0302 clinical medicine, Sulfation, Neoplasms, Humans, 030304 developmental biology, Sialic Acid Binding Immunoglobulin-like Lectins, 0303 health sciences, biology, Sulfates, Ligand, Chemistry, Ligand binding assay, SIGLEC, General Medicine, respiratory system, N-Acetylneuraminic Acid, Up-Regulation, Cell biology, Cell culture, 030220 oncology & carcinogenesis, biology.protein, Carbohydrate Metabolism, Molecular Medicine, Protein Processing, Post-Translational, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a58d2915757580089f07892034a10641
https://doi.org/10.1021/acschembio.1c00501

المؤلفون: Madelene Ho, Chris D. St. Laurent, Kelli A. McCord, Abhishek Bhattacherjee, Ghazaleh Eskandari-Sedighi, Sameera Zia, Matthew S. Macauley, Jaesoo Jung, Gaurav Sidhu, Jason R. Plemel, Arjun Bains, Susmita Sarkar

المصدر: Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-22 (2021)

مصطلحات موضوعية: 0301 basic medicine, Genetically modified mouse, Gene isoform, Immunomodulatory, Isoform, Phagocytosis, Cell, lcsh:Geriatrics, lcsh:RC346-429, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Downregulation and upregulation, medicine, Molecular Biology, Gene, lcsh:Neurology. Diseases of the nervous system, Microglia, biology, Cell biology, lcsh:RC952-954.6, 030104 developmental biology, medicine.anatomical_structure, biology.protein, Neurology (clinical), Antibody, CD33, Alzheimer’s disease, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf832cb6f85bf4d28a1c0ce4f84ecb4b
https://doaj.org/article/9d903e7fcaaf46188f4b75d343f185d2

المؤلفون: Abhishek Bhattacherjee, Chris D. St. Laurent, Ghazaleh Eskandari-Sedighi, Gour Chand Daskhan, Anastassia Voronova, Arjun Bains, Adrianne E.S. Watson, Matthew S. Macauley

المصدر: Journal of controlled release : official journal of the Controlled Release Society. 338

مصطلحات موضوعية: Glycan, Phagocytosis, media_common.quotation_subject, Pharmaceutical Science, Ligands, Mice, Alzheimer Disease, Polysaccharides, medicine, Animals, Internalization, media_common, Liposome, Microglia, biology, Chemistry, Neurodegeneration, SIGLEC, medicine.disease, Cell biology, medicine.anatomical_structure, Liposomes, biology.protein, Intracellular

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::850efb12eeb818fbbff2d850a13cea6b
https://pubmed.ncbi.nlm.nih.gov/34517042

المؤلفون: Chris D. St. Laurent, Anastassia Voronova, Matthew S. Macauley, Adrianne E.S. Watson, Abhishek Bhattacherjee, Arjun Bains, Gour Chand Daskhan, Ghazaleh Eskandari-Sedighi

مصطلحات موضوعية: Glycan, Liposome, Microglia, biology, Chemistry, media_common.quotation_subject, Phagocytosis, Neurodegeneration, Cell, medicine.disease, Cell biology, medicine.anatomical_structure, medicine, biology.protein, Internalization, Intracellular, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ec5b09dfc8240aca35e445eb44b65a16
https://doi.org/10.1101/2021.05.08.443135

المؤلفون: Abhishek, Bhattacherjee, Jaesoo, Jung, Sameera, Zia, Madelene, Ho, Ghazaleh, Eskandari-Sedighi, Chris D, St Laurent, Kelli A, McCord, Arjun, Bains, Gaurav, Sidhu, Susmita, Sarkar, Jason R, Plemel, Matthew S, Macauley

المصدر: Molecular Neurodegeneration

مصطلحات موضوعية: Male, Immunomodulatory, Isoform, Sialic Acid Binding Ig-like Lectin 3, Mice, Transgenic, Mouse model, Phagocytosis, Polysaccharides, Animals, Humans, Protein Isoforms, Gene Regulatory Networks, Gain-of-function, RNA-Seq, Genes, Immediate-Early, Alleles, Crosses, Genetic, Gene Editing, Amyloid beta-Peptides, U937 Cells, Peptide Fragments, Mice, Inbred C57BL, Gain of Function Mutation, Female, Microglia, CRISPR-Cas Systems, Single-Cell Analysis, CD33, Alzheimer’s disease, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::4ddb1344de5ae145530af3b293661d5e
https://pubmed.ncbi.nlm.nih.gov/33766097

المؤلفون: Jean-Philippe Julien, Fahima Mozaneh, Heajin Park, Chris D. St. Laurent, John S. Klassen, Vivian Aghanya, Sepideh Soukhtehzari, Laura Streith, Susmita Sarkar, Matthew S. Macauley, Elena N. Kitova, Jaesoo Jung, Caleb Loo, Lori J. West, Emily Rodrigues, Gour Chand Daskhan, Karla C. Williams

مصطلحات موضوعية: On cells, Glycan, Scaffold, Biochemistry, biology, Chemistry, Ligand, CD33, biology.protein, Enhanced sensitivity, SIGLEC, respiratory system, Receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6113ae9c0dc6b72cf90d595598782b9a
https://doi.org/10.1101/2020.07.28.223164

المؤلفون: Pia D. Vogel, A. Dean Befus, David Rosenfield, Richard J. Auchus, Ana F. Trueba, Chris D. St. Laurent, Eduardo Reyes-Serratos, Chelsey A. Werchan, Thomas Ritz

المصدر: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 312:R1004-R1016

مصطلحات موضوعية: Adult, Male, Vascular Endothelial Growth Factor A, 0301 basic medicine, medicine.medical_specialty, Saliva, Time Factors, Adolescent, Hydrocortisone, Physiology, Leukotriene B4, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Respiratory Rate, Heart Rate, Forced Expiratory Volume, Physiology (medical), Internal medicine, Calcium-binding protein, medicine, Humans, Speech, Spermatid, business.industry, Calcium-Binding Proteins, Mathematical Concepts, Middle Aged, Submandibular gland, Asthma, Up-Regulation, Molecular Weight, Affect, 030104 developmental biology, medicine.anatomical_structure, Endocrinology, Female, business, Biomarkers, Stress, Psychological, 030217 neurology & neurosurgery, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d3ecda098e5ba1c7104d4c7b32984ba
https://doi.org/10.1152/ajpregu.00393.2016

المؤلفون: Tae Chul Moon, Chris D. St. Laurent, Kurtis Ng, C. Marcet, A. Dean Befus, Harissios Vliagoftis, Javeria Raheem

المصدر: Antiviral research. 171

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_treatment, 030106 microbiology, Antiviral protein, Biology, medicine.disease_cause, Virus Replication, Cell Line, 03 medical and health sciences, chemistry.chemical_compound, Virology, Influenza, Human, Influenza A virus, medicine, Humans, Mast Cells, Virus Release, Disease Resistance, Pharmacology, Innate immune system, Epithelial Cells, Mast cell, Molecular biology, 3. Good health, 030104 developmental biology, Cytokine, medicine.anatomical_structure, chemistry, Viperin, Host-Pathogen Interactions, Cytokines, Prostaglandin D2, Histamine, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e52d033fc12d68d2d9bfdfd7d415d941
https://pubmed.ncbi.nlm.nih.gov/31348951

المؤلفون: Ronald Mathison, Katherine E. St. Laurent, Chris D. St. Laurent, A. Dean Befus

المصدر: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 308:R569-R575

مصطلحات موضوعية: Lipopolysaccharides, Male, Saliva, medicine.medical_specialty, Neutrophils, Ovalbumin, Physiology, Amino Acid Motifs, Anti-Inflammatory Agents, Salivary Glands, Rats, Sprague-Dawley, Physiology (medical), Internal medicine, Calcium-binding protein, medicine, Animals, Humans, RNA, Messenger, Protein Precursors, Salivary Proteins and Peptides, Anaphylaxis, Regulation of gene expression, Mice, Inbred BALB C, Dose-Response Relationship, Drug, Spermatid, biology, Calcium-Binding Proteins, Biological activity, Pneumonia, Peptide Fragments, Cell biology, Disease Models, Animal, medicine.anatomical_structure, Endocrinology, Gene Expression Regulation, Neutrophil Infiltration, Call for Papers, biology.protein, Homeostasis, Hormone

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dde82761d478cb2a9fef2293eb045bb
https://doi.org/10.1152/ajpregu.00153.2014

المؤلفون: Ioannis S. Dimopoulos, Alina Radziwon, Chris D. St. Laurent, Ian M. MacDonald

المصدر: Current opinion in ophthalmology. 28(5)

مصطلحات موضوعية: 0301 basic medicine, General Medicine, Genetic Therapy, Retinal Pigment Epithelium, 03 medical and health sciences, Ophthalmology, 030104 developmental biology, 0302 clinical medicine, Phenotype, Mutation, 030221 ophthalmology & optometry, Humans, Choroideremia, Adaptor Proteins, Signal Transducing

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e784b7036304a9c28012bb394daee6
https://pubmed.ncbi.nlm.nih.gov/28520608