نتائج البحث - "Chou, Wayne K. W."

1

Academic Journal

Structural studies of geosmin synthase, a bifunctional sesquiterpene synthase with ?? domain architecture that catalyzes a unique cyclization-fragmentation reaction sequence

المؤلفون: Harris, Golda G., Lombardi, Patrick M., Pemberton, Travis A., Matsui, Tsutomu, Weiss, Thomas M., Cole, Kathryn E., Köksal, Mustafa, Murphy, Frank V., Vedula, L. Sangeetha, Chou, Wayne K. W., Cane, David E., Christianson, David W.

مصطلحات موضوعية: Cyclization, Acetone, Streptomyces coelicolor, Crystal structure, Catalysis, Geosmin synthase

جغرافية الموضوع: 10.1021/acs.biochem.5b01143

Relation: Biochemistry; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; Harris, G. G., Lombardi, P. M., Pemberton, T. A., Matsui, T., Weiss, T. M., Cole, K. E., Köksal, M., .Christianson, D. W. (2015). Structural studies of geosmin synthase, a bifunctional sesquiterpene synthase with αα domain architecture that catalyzes a unique cyclization-fragmentation reaction sequence. Biochemistry, 54(48), 7142-7155. doi:10.1021/acs.biochem.5b01143; http://doi.org/10.1021/acs.biochem.5b01143; http://hdl.handle.net/11147/5841; 54; 48; 7142; 7155; WOS:000366339300010; 2-s2.0-84948962778

الاتاحة: http://hdl.handle.net/11147/5841
https://doi.org/10.1021/acs.biochem.5b01143

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2

Academic Journal

Reprogramming the Chemodiversity of Terpenoid Cyclization by Remolding the Active Site Contour of epi-Isozizaene Synthase

المؤلفون: Li, Ruiqiong, Chou, Wayne K. W., Himmelberger, Julie A., Litwin, Kevin M., Harris, Golda G., Cane, David E., Christianson, David W.

المساهمون: National Institutes of Health

المصدر: Biochemistry ; volume 53, issue 7, page 1155-1168 ; ISSN 0006-2960 1520-4995

الاتاحة: http://dx.doi.org/10.1021/bi401643u
https://pubs.acs.org/doi/pdf/10.1021/bi401643u

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3

Probing the Role of Active Site Water in the Sesquiterpene Cyclization Reaction Catalyzed by Aristolochene Synthase

المؤلفون: Chen, Mengbin, Chou, Wayne K. W., Al-Lami, Naeemah, Faraldos, Juan A., Allemann, Rudolf K., Cane, David E., Christianson, David W.

مصطلحات موضوعية: 59 BASIC BIOLOGICAL SCIENCES, 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY

وصف الملف: application/pdf

Relation: http://www.osti.gov/servlets/purl/1255308; https://www.osti.gov/biblio/1255308; https://doi.org/10.1021/acs.biochem.6b00343

الاتاحة: http://www.osti.gov/servlets/purl/1255308
https://www.osti.gov/biblio/1255308
https://doi.org/10.1021/acs.biochem.6b00343

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4

Academic Journal

Substitution of Aromatic Residues with Polar Residues in the Active Site Pocket of epi-Isozizaene Synthase Leads to the Generation of New Cyclic Sesquiterpenes

المؤلفون: Blank, Patrick N., Barrow, Golda H., Chou, Wayne K. W., Duan, Lian, Cane, David E., Christianson, David W.

المساهمون: National Institute of General Medical Sciences

المصدر: Biochemistry ; volume 56, issue 43, page 5798-5811 ; ISSN 0006-2960 1520-4995

الاتاحة: http://dx.doi.org/10.1021/acs.biochem.7b00895
https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.7b00895

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5

Academic Journal

Exploring the Influence of Domain Architecture on the Catalytic Function of Diterpene Synthases

المؤلفون: Pemberton, Travis A., Chen, Mengbin, Harris, Golda G., Chou, Wayne K. W., Duan, Lian, Köksal, Mustafa, Genshaft, Alex S., Cane, David E., Christianson, David W.

المساهمون: National Institute of General Medical Sciences

المصدر: Biochemistry ; volume 56, issue 14, page 2010-2023 ; ISSN 0006-2960 1520-4995

الاتاحة: http://dx.doi.org/10.1021/acs.biochem.7b00137
https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.7b00137

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6

Academic Journal

Structure and Function of Fusicoccadiene Synthase, a Hexameric Bifunctional Diterpene Synthase

المؤلفون: Chen, Mengbin, Chou, Wayne K. W., Toyomasu, Tomonobu, Cane, David E., Christianson, David W.

المساهمون: Radcliffe Institute for Advanced Study, Harvard University, Office of Science, National Institute of General Medical Sciences

المصدر: ACS Chemical Biology ; volume 11, issue 4, page 889-899 ; ISSN 1554-8929 1554-8937

الاتاحة: http://dx.doi.org/10.1021/acschembio.5b00960
https://pubs.acs.org/doi/pdf/10.1021/acschembio.5b00960

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7

Academic Journal

The T296V Mutant of Amorpha-4,11-diene Synthase Is Defective in Allylic Diphosphate Isomerization but Retains the Ability To Cyclize the Intermediate (3 R)-Nerolidyl Diphosphate to Amorpha-4,11-diene

المؤلفون: Li, Zhenqiu, Gao, Ruiping, Hao, Qinggang, Zhao, Huifang, Cheng, Longbin, He, Fang, Liu, Li, Liu, Xiuhua, Chou, Wayne K. W., Zhu, Huajie, Cane, David E.

المساهمون: National Natural Science Foundation of China, National Institutes of Health, Bioengineering key discipline of Hebei Province, Hebei University postdoctoral grants

المصدر: Biochemistry ; volume 55, issue 48, page 6599-6604 ; ISSN 0006-2960 1520-4995

الاتاحة: http://dx.doi.org/10.1021/acs.biochem.6b01004
https://pubs.acs.org/doi/pdf/10.1021/acs.biochem.6b01004

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