المؤلفون: Yang, Neil V, Chao, Justin Y, Garton, Kelly A, Tran, Tommy, King, Sarah M, Orr, Joseph, Oei, Jacob H, Crawford, Alexandra, Kang, Misun, Zalpuri, Reena, Jorgens, Danielle M, Konchadi, Pranav, Chorba, John S, Theusch, Elizabeth, Krauss, Ronald M

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Nutrition, Genetics, Liver Disease, Digestive Diseases, 2.1 Biological and endogenous factors, 1.1 Normal biological development and functioning, Metabolic and endocrine, ApoE, LXR, Lipid metabolism, Mitochondria, Mitochondria-ER contact sites, TOMM40, Physiology, Biochemistry and cell biology

URL الوصول: https://escholarship.org/uc/item/8w62g99t

المؤلفون: Chorba, John S

المصدر: Nature Cardiovascular Research. 3(1)

مصطلحات موضوعية: Philosophy and Religious Studies, History and Philosophy Of Specific Fields, Generic health relevance

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/3rc970b2

المؤلفون: Boctor, Daniel, Bakke, Brian, Chorba, John S

مصطلحات موضوعية: Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Cardiovascular

URL الوصول: https://escholarship.org/uc/item/2q6340c4

المؤلفون: Chorba, John S, Galvan, Adri M, Shokat, Kevan M

مصطلحات موضوعية: Biochemistry and Cell Biology, Psychology, Cognitive Sciences

URL الوصول: https://escholarship.org/uc/item/2bc6f4gs

المؤلفون: Xia, Vivian Q, Ong, Chui Mei, Zier, Lucas S, MacGregor, John S, Wu, Alan HB, Chorba, John S

المصدر: Arteriosclerosis, thrombosis, and vascular biology. 43(2)

مصطلحات موضوعية: Animals, Humans, Serine Endopeptidases, Subtilisins, Proprotein Convertases, Heparin, Receptors, LDL, Cholesterol, LDL, Heparan Sulfate Proteoglycans, Proprotein Convertase 9, cholesterol, heart disease, heparin, hepatocyte, lipoproteins, liver, translational research, Digestive Diseases, Heart Disease, Cardiovascular, Aetiology, 2.1 Biological and endogenous factors, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Cardiovascular System & Hematology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/6z43z9kv

المؤلفون: Chorba, John S, Xia, Vivian Q, Smith, Geoffrey A, Padmanabhan, Arun

المصدر: Bio-protocol. 13(2)

مصطلحات موضوعية: CRISPRi, Flow cytometry, Forward genetics, Hit validation

URL الوصول: https://escholarship.org/uc/item/7sk8q6zm

المؤلفون: Smith, Geoffrey A, Padmanabhan, Arun, Lau, Bryan H, Pampana, Akhil, Li, Li, Lee, Clara Y, Pelonero, Angelo, Nishino, Tomohiro, Sadagopan, Nandhini, Xia, Vivian Q, Jain, Rajan, Natarajan, Pradeep, Wu, Roland S, Black, Brian L, Srivastava, Deepak, Shokat, Kevan M, Chorba, John S

المصدر: Science Translational Medicine. 14(662)

مصطلحات موضوعية: Medical Biotechnology, Biomedical and Clinical Sciences, Atherosclerosis, Heart Disease, Digestive Diseases, Heart Disease - Coronary Heart Disease, Cardiovascular, Genetics, Biotechnology, Aetiology, 2.1 Biological and endogenous factors, Animals, Cold-Shock Response, DNA-Binding Proteins, Humans, Mice, Proprotein Convertase 9, RNA, Messenger, RNA-Binding Proteins, Receptors, LDL, Transcription, Genetic, Biological Sciences, Medical and Health Sciences, Medical biotechnology, Biomedical engineering

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/41x481zw

المؤلفون: Maidens, John, Chorba, John S, Thomas, James D

المصدر: JAMA Internal Medicine. 182(5)

مصطلحات موضوعية: Health Services and Systems, Biomedical and Clinical Sciences, Clinical Sciences, Health Sciences, Heart Sounds, Humans, Physical Examination, Opthalmology and Optometry, Public Health and Health Services, Clinical sciences, Health services and systems

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5wn0b2gp

المؤلفون: Guo, Ling, Tiwari, Urvi, Lastowski, Emileigh, Chorba, John S, Ilyas, Suleman, Currie, Caroline, Choudhary, Gaurav, Maidens, John, Saltman, Adam

المصدر: Circulation. 144(Suppl_1)

مصطلحات موضوعية: Cardiovascular, Good Health and Well Being, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Public Health and Health Services, Cardiovascular System & Hematology

URL الوصول: https://escholarship.org/uc/item/5032s0mz

المؤلفون: Chorba, John S, Shapiro, Avi M, Le, Le, Maidens, John, Prince, John, Pham, Steve, Kanzawa, Mia M, Barbosa, Daniel N, Currie, Caroline, Brooks, Catherine, White, Brent E, Huskin, Anna, Paek, Jason, Geocaris, Jack, Elnathan, Dinatu, Ronquillo, Ria, Kim, Roy, Alam, Zenith H, Mahadevan, Vaikom S, Fuller, Sophie G, Stalker, Grant W, Bravo, Sara A, Jean, Dina, Lee, John J, Gjergjindreaj, Medeona, Mihos, Christos G, Forman, Steven T, Venkatraman, Subramaniam, McCarthy, Patrick M, Thomas, James D

المصدر: Journal of the American Heart Association. 10(9)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Clinical Trials and Supportive Activities, Bioengineering, Clinical Research, Heart Disease, Cardiovascular, 4.2 Evaluation of markers and technologies, Detection, screening and diagnosis, Good Health and Well Being, Adolescent, Adult, Aged, Aged, 80 and over, Algorithms, Cross-Sectional Studies, Deep Learning, Diagnosis, Computer-Assisted, Equipment Design, Female, Heart Auscultation, Heart Murmurs, Humans, Male, Middle Aged, Reproducibility of Results, Stethoscopes, Young Adult, auscultation, machine learning, neural networks, physical examination, valvular heart disease, Cardiorespiratory Medicine and Haematology, Cardiovascular medicine and haematology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/95x1r6x2

المؤلفون: Gordon, David E, Jang, Gwendolyn M, Bouhaddou, Mehdi, Xu, Jiewei, Obernier, Kirsten, White, Kris M, O’Meara, Matthew J, Rezelj, Veronica V, Guo, Jeffrey Z, Swaney, Danielle L, Tummino, Tia A, Hüttenhain, Ruth, Kaake, Robyn M, Richards, Alicia L, Tutuncuoglu, Beril, Foussard, Helene, Batra, Jyoti, Haas, Kelsey, Modak, Maya, Kim, Minkyu, Haas, Paige, Polacco, Benjamin J, Braberg, Hannes, Fabius, Jacqueline M, Eckhardt, Manon, Soucheray, Margaret, Bennett, Melanie J, Cakir, Merve, McGregor, Michael J, Li, Qiongyu, Meyer, Bjoern, Roesch, Ferdinand, Vallet, Thomas, Mac Kain, Alice, Miorin, Lisa, Moreno, Elena, Naing, Zun Zar Chi, Zhou, Yuan, Peng, Shiming, Shi, Ying, Zhang, Ziyang, Shen, Wenqi, Kirby, Ilsa T, Melnyk, James E, Chorba, John S, Lou, Kevin, Dai, Shizhong A, Barrio-Hernandez, Inigo, Memon, Danish, Hernandez-Armenta, Claudia, Lyu, Jiankun, Mathy, Christopher JP, Perica, Tina, Pilla, Kala Bharath, Ganesan, Sai J, Saltzberg, Daniel J, Rakesh, Ramachandran, Liu, Xi, Rosenthal, Sara B, Calviello, Lorenzo, Venkataramanan, Srivats, Liboy-Lugo, Jose, Lin, Yizhu, Huang, Xi-Ping, Liu, YongFeng, Wankowicz, Stephanie A, Bohn, Markus, Safari, Maliheh, Ugur, Fatima S, Koh, Cassandra, Savar, Nastaran Sadat, Tran, Quang Dinh, Shengjuler, Djoshkun, Fletcher, Sabrina J, O’Neal, Michael C, Cai, Yiming, Chang, Jason CJ, Broadhurst, David J, Klippsten, Saker, Sharp, Phillip P, Wenzell, Nicole A, Kuzuoglu-Ozturk, Duygu, Wang, Hao-Yuan, Trenker, Raphael, Young, Janet M, Cavero, Devin A, Hiatt, Joseph, Roth, Theodore L, Rathore, Ujjwal, Subramanian, Advait, Noack, Julia, Hubert, Mathieu, Stroud, Robert M, Frankel, Alan D, Rosenberg, Oren S, Verba, Kliment A, Agard, David A, Ott, Melanie, Emerman, Michael, Jura, Natalia

المصدر: Nature. 583(7816)

مصطلحات موضوعية: Biological Sciences, Bioinformatics and Computational Biology, Biomedical and Clinical Sciences, Coronaviruses Therapeutics and Interventions, Emerging Infectious Diseases, Infectious Diseases, Coronaviruses, 5.1 Pharmaceuticals, Infection, Good Health and Well Being, Animals, Antiviral Agents, Betacoronavirus, COVID-19, Chlorocebus aethiops, Cloning, Molecular, Coronavirus Infections, Drug Evaluation, Preclinical, Drug Repositioning, HEK293 Cells, Host-Pathogen Interactions, Humans, Immunity, Innate, Mass Spectrometry, Molecular Targeted Therapy, Pandemics, Pneumonia, Viral, Protein Binding, Protein Biosynthesis, Protein Domains, Protein Interaction Mapping, Protein Interaction Maps, Receptors, sigma, SARS-CoV-2, SKP Cullin F-Box Protein Ligases, Vero Cells, Viral Proteins, COVID-19 Drug Treatment, General Science & Technology

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/2gt3q50x
https://escholarship.org/content/qt2gt3q50x/qt2gt3q50x.pdf

المؤلفون: Gordon, David E, Jang, Gwendolyn M, Bouhaddou, Mehdi, Xu, Jiewei, Obernier, Kirsten, O'Meara, Matthew J, Guo, Jeffrey Z, Swaney, Danielle L, Tummino, Tia A, Hüttenhain, Ruth, Kaake, Robyn M, Richards, Alicia L, Tutuncuoglu, Beril, Foussard, Helene, Batra, Jyoti, Haas, Kelsey, Modak, Maya, Kim, Minkyu, Haas, Paige, Polacco, Benjamin J, Braberg, Hannes, Fabius, Jacqueline M, Eckhardt, Manon, Soucheray, Margaret, Bennett, Melanie J, Cakir, Merve, McGregor, Michael J, Li, Qiongyu, Naing, Zun Zar Chi, Zhou, Yuan, Peng, Shiming, Kirby, Ilsa T, Melnyk, James E, Chorba, John S, Lou, Kevin, Dai, Shizhong A, Shen, Wenqi, Shi, Ying, Zhang, Ziyang, Barrio-Hernandez, Inigo, Memon, Danish, Hernandez-Armenta, Claudia, Mathy, Christopher JP, Perica, Tina, Pilla, Kala B, Ganesan, Sai J, Saltzberg, Daniel J, Ramachandran, Rakesh, Liu, Xi, Rosenthal, Sara B, Calviello, Lorenzo, Venkataramanan, Srivats, Lin, Yizhu, Wankowicz, Stephanie A, Bohn, Markus, Trenker, Raphael, Young, Janet M, Cavero, Devin, Hiatt, Joe, Roth, Theo, Rathore, Ujjwal, Subramanian, Advait, Noack, Julia, Hubert, Mathieu, Roesch, Ferdinand, Vallet, Thomas, Meyer, Björn, White, Kris M, Miorin, Lisa, Agard, David, Emerman, Michael, Ruggero, Davide, García-Sastre, Adolfo, Jura, Natalia, von Zastrow, Mark, Taunton, Jack, Schwartz, Olivier, Vignuzzi, Marco, d'Enfert, Christophe, Mukherjee, Shaeri, Jacobson, Matt, Malik, Harmit S, Fujimori, Danica G, Ideker, Trey, Craik, Charles S, Floor, Stephen, Fraser, James S, Gross, John, Sali, Andrej, Kortemme, Tanja, Beltrao, Pedro, Shokat, Kevan, Shoichet, Brian K, Krogan, Nevan J

مصطلحات موضوعية: Prevention, Vaccine Related, Biodefense, Infectious Diseases, Rare Diseases, Pneumonia & Influenza, Emerging Infectious Diseases, Lung, Pneumonia, 5.1 Pharmaceuticals, 2.2 Factors relating to the physical environment, Infection

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/9v71w6zc

المؤلفون: Smith, Geoffrey A, Padmanabhan, Arun, Lau, Bryan H, Pampana, Akhil, Li, Li, Lee, Y Clara, Pelonero, Angelo, Nishino, Tomohiro, Sadagopan, Nandhini, Jain, Rajan, Natarajan, Pradeep, Wu, Roland S, Black, Brian L, Srivastava, Deepak, Shokat, Kevan M, Chorba, John S

مصطلحات موضوعية: Biochemistry and Cell Biology, Biomedical and Clinical Sciences, Genetics, Biological Sciences, Heart Disease, Digestive Diseases, Heart Disease - Coronary Heart Disease, Biotechnology, Atherosclerosis, Human Genome, Cardiovascular, Aetiology, Underpinning research, 1.1 Normal biological development and functioning, 2.1 Biological and endogenous factors, Good Health and Well Being

URL الوصول: https://escholarship.org/uc/item/9vs9n115

المؤلفون: Galvan, Adri M, Chorba, John S

المصدر: Journal of Lipid Research. 60(1)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Cardiovascular, 2.1 Biological and endogenous factors, Aetiology, Gene Expression Regulation, HEK293 Cells, Hep G2 Cells, Heparin, Heparin Lyase, Humans, Lipoproteins, LDL, Proprotein Convertase 9, Protein Transport, Receptors, LDL, atherosclerosis, cholesterol, lipoprotein metabolism, receptors/lipoprotein, dyslipidemias, low density lipoprotein receptor, single nucleotide polymorphism, familial hypercholesterolemia, coreceptor, mechanism, low density lipoprotein, proprotein convertase subtilisin/kexin type 9, Medical Biochemistry and Metabolomics, Biochemistry & Molecular Biology, Biochemistry and cell biology, Medical biochemistry and metabolomics

URL الوصول: https://escholarship.org/uc/item/2r51n7tn

المؤلفون: Chorba, John S, Galvan, Adri M, Shokat, Kevan M

المصدر: Journal of visualized experiments : JoVE. 2018(138)

مصطلحات موضوعية: Humans, Luciferases, Proteolysis, Proprotein Convertase 9, Biochemistry, Issue 138, Proprotein convertase subtilisin/kexin type 9, protease, substrate specificity, high-throughput assay, luciferase, low-density lipoprotein, low-density lipoprotein receptor, single nucleotide polymorphism, drug screening, Genetics, Cardiovascular, Biochemistry and Cell Biology, Psychology, Cognitive Sciences

URL الوصول: https://escholarship.org/uc/item/6rb1918z

المؤلفون: Chorba, John S, Galvan, Adri M, Shokat, Kevan M

المصدر: Journal of Biological Chemistry. 293(18)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Chemical Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

URL الوصول: https://escholarship.org/uc/item/81w2c5k3

المؤلفون: Chorba, John S, Shokat, Kevan M

المصدر: Journal of Biological Chemistry. 289(42)

مصطلحات موضوعية: Biochemistry and Cell Biology, Biological Sciences, Allosteric Site, Atherosclerosis, Catalytic Domain, Gene Expression Regulation, HEK293 Cells, Heart Diseases, Humans, Hypercholesterolemia, Mutagenesis, Mutation, Phenotype, Proprotein Convertase 9, Proprotein Convertases, Protein Binding, Protein Transport, Proteolysis, Serine Endopeptidases, Active Site, Low Density Lipoprotein, Proprotein Convertase Subtilisin/Kexin Type 9, Protein Secretion, Substrate Specificity, Chemical Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/5460h2c9
https://escholarship.org/content/qt5460h2c9/qt5460h2c9.pdf

المؤلفون: Gordon, David E., Jang, Gwendolyn M., Bouhaddou, Mehdi, Xu, Jiewei, Obernier, Kirsten, White, Kris M., O’Meara, Matthew J., Rezelj, Veronica V., Guo, Jeffrey Z., Swaney, Danielle L., Tummino, Tia A., Huettenhain, Ruth, Kaake, Robyn M., Richards, Alicia L., Tutuncuoglu, Beril, Foussard, Helene, Batra, Jyoti, Haas, Kelsey, Modak, Maya, Kim, Minkyu, Haas, Paige, Polacco, Benjamin J., Braberg, Hannes, Fabius, Jacqueline M., Eckhardt, Manon, Soucheray, Margaret, Bennett, Melanie J., Cakir, Merve, McGregor, Michael J., Li, Qiongyu, Meyer, Bjoern, Roesch, Ferdinand, Vallet, Thomas, Mac Kain, Alice, Miorin, Lisa, Moreno, Elena, Naing, Zun Zar Chi, Zhou, Yuan, Peng, Shiming, Shi, Ying, Zhang, Ziyang, Shen, Wenqi, Kirby, Ilsa T., Melnyk, James E., Chorba, John S., Lou, Kevin, Dai, Shizhong A., Barrio-Hernandez, Inigo, Memon, Danish, Hernandez-Armenta, Claudia, Lyu, Jiankun, Mathy, Christopher J.P., Perica, Tina, Pilla, Kala B., Ganesan, Sai J., Saltzberg, Daniel J., Rakesh, Ramachandran, Liu, Xi, Rosenthal, Sara B., Calviello, Lorenzo, Venkataramanan, Srivats, Liboy-Lugo, Jose, Lin, Yizhu, Huang, Xi Ping, Liu, Yong Feng, Wankowicz, Stephanie A., Bohn, Markus, Safari, Maliheh, Ugur, Fatima S., Koh, Cassandra, Savar, Nastaran Sadat, Tran, Quang Dinh, Shengjuler, Djoshkun, Fletcher, Sabrina J., O’Neal, Michael C., Cai, Yiming, Chang, Jason C.J., Broadhurst, David J., Klippsten, Saker, Sharp, Phillip P., Wenzell, Nicole A., Kuzuoglu, Duygu, Wang, Hao Yuan, Trenker, Raphael, Young, Janet M., Cavero, Devin A., Hiatt, Joseph, Roth, Theodore L., Rathore, Ujjwal, Subramanian, Advait, Noack, Julia, Hubert, Mathieu, Stroud, Robert M., Frankel, Alan D., Rosenberg, Oren S., Verba, Kliment A., Agard, David A., Ott, Melanie, Emerman, Michael, Jura, Natalia, von Zastrow, Mark, Verdin, Eric, Ashworth, Alan, Schwartz, Olivier, d’Enfert, Christophe, Mukherjee, Shaeri, Jacobson, Matt, Malik, Harmit S., Fujimori, Danica G., Ideker, Trey, Craik, Charles S., Floor, Stephen N., Fraser, James S., Gross, John D., Sali, Andrej, Roth, Bryan L., Ruggero, Davide, Taunton, Jack, Kortemme, Tanja, Beltrao, Pedro, Vignuzzi, Marco, García-Sastre, Adolfo, Shokat, Kevan M., Shoichet, Brian K., Krogan, Nevan J.

المصدر: reponame:Expeditio Repositorio Institucional UJTL ; instname:Universidad de Bogotá Jorge Tadeo Lozano

مصطلحات موضوعية: COVID-19, Síndrome respiratorio agudo grave, SARS-CoV-2, Coronavirus

وصف الملف: 30 páginas; application/pdf

Relation: https://www.nature.com/articles/s41586-020-2286-9; http://hdl.handle.net/20.500.12010/10883; https://doi.org/10.1038/s41586-020-2286-9

الاتاحة: https://hdl.handle.net/20.500.12010/10883
https://www.nature.com/articles/s41586-020-2286-9
https://doi.org/10.1038/s41586-020-2286-9

المؤلفون: Xia, Vivian Q, Xia, Vivian Q, Ong, Chui Mei, Zier, Lucas S, MacGregor, John S, Wu, Alan HB, Chorba, John S

المصدر: Arteriosclerosis, thrombosis, and vascular biology; vol 43, iss 2, 352-358; 1079-5642

مصطلحات الفهرس: animal models, cholesterol, heart disease, hepatocyte, liver, Heart Disease, Digestive Diseases, Cardiovascular, Aetiology, 2.1 Biological and endogenous factors, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Cardiovascular System & Hematology, article

URL: https://escholarship.org/uc/item/6z43z9kv
https://escholarship.org/

المؤلفون: Yang, Neil V., Chao, Justin Y., Garton, Kelly A., Tran, Tommy, King, Sarah M., Orr, Joseph, Oei, Jacob H., Crawford, Alexandra, Kang, Misun, Zalpuri, Reena, Jorgens, Danielle M., Konchadi, Pranav, Chorba, John S., Theusch, Elizabeth, Krauss, Ronald M.

المصدر: Molecular Metabolism; Dec2024, Vol. 90, pN.PAG-N.PAG, 1p