المؤلفون: van Delft, M.F., Chappaz, S., Khakham, Y., Bui, C.T., Debrincat, M.A., Lowes, K.N., Brouwer, J.M., Grohmann, C., Sharp, P.P., Dagley, L.F., Li, L., McArthur, K., Luo, M.-X., Chin, H.S., Fairlie, W.D., Lee, E.F., Segal, D., Duflocq, S., Lessene, R., Bernard, S.

المصدر: http://dx.doi.org/10.1038/s41589-019-0365-8.

مصطلحات موضوعية: Cell death, screening, small molecules, target validation

Relation: http://purl.org/au-research/grants/nhmrc/1083077; http://purl.org/au-research/grants/nhmrc/9000220; http://purl.org/au-research/grants/nhmrc/1016701; http://purl.org/au-research/grants/nhmrc/1078924; http://purl.org/au-research/grants/nhmrc/461221; http://purl.org/au-research/grants/nhmrc/1113133; http://purl.org/au-research/grants/nhmrc/1024620; http://purl.org/au-research/grants/nhmrc/1117089; http://purl.org/au-research/grants/nhmrc/1022618; http://purl.org/au-research/grants/nhmrc/GNT1158137; http://purl.org/au-research/grants/nhmrc/461219; http://purl.org/au-research/grants/nhmrc/1016647; http://purl.org/au-research/grants/nhmrc/1079700; http://purl.org/au-research/grants/nhmrc/1043149; http://purl.org/au-research/grants/nhmrc/1063008; Nature Chemical Biology, 2019; 15(11):1057-1066; http://hdl.handle.net/2440/121678; Kile, B.T. [0000-0002-8836-8947]

الاتاحة: http://hdl.handle.net/2440/121678
https://doi.org/10.1038/s41589-019-0365-8

المؤلفون: McArthur, K., Whitehead, L.W., Heddleston, J.M., Li, L., Padman, B.S., Oorschot, V., Geoghegan, N.D., Chappaz, S., Davidson, S., Chin, H.S., Lane, R.M., Dramicanin, M., Saunders, T.L., Sugiana, C., Lessene, R., Osellame, L.D., Chew, T.L., Dewson, G., Lazarou, M., Ramm, G.

المصدر: http://dx.doi.org/10.1126/science.aao6047.

مصطلحات موضوعية: Mice, Inbred C57BL

Relation: http://purl.org/au-research/grants/arc/FT160100063; http://purl.org/au-research/grants/arc/LE120100090; http://purl.org/au-research/grants/arc/LE100100165; http://purl.org/au-research/grants/arc/DP16012176; http://purl.org/au-research/grants/nhmrc/361646; Science, 2018; 359(6378):883-+; http://hdl.handle.net/2440/121707; Kile, B.T. [0000-0002-8836-8947]

الاتاحة: http://hdl.handle.net/2440/121707
https://doi.org/10.1126/science.aao6047

المؤلفون: Ko T.K., Chin H.S., Chuah C.T.H., Huang J.W.J., Ng K.-P., Khaw S.L., Huang D.C.S., Ong S.T.

المساهمون: DUKE-NUS MEDICAL SCHOOL

المصدر: Unpaywall 20200831

مصطلحات موضوعية: 4 [4 (4' chloro 2 biphenylylmethyl) 1 piperazinyl] n [4 [3 dimethylamino 1 (phenylthiomethyl)propylamino] 3 nitrobenzenesulfonyl]benzamide, BIM protein, imatinib, 4-methyl-N-(3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-((4-pyridin-3-ylpyrimidin-2-yl)amino)benzamide, ABT-737, apoptosis regulatory protein, BCR ABL protein, BCR-ABL1 fusion protein, human, biphenyl derivative, dasatinib, membrane protein, nitrophenol, oncoprotein, piperazine derivative, protein kinase inhibitor, pyrimidine derivative, sulfonamide, antineoplastic activity, apoptosis, Article, BCR ABL1 gene, BIM gene, cancer resistance, cell growth, chronic myeloid leukemia, concentration response, controlled study, drug mechanism, gene

Relation: Ko T.K., Chin H.S., Chuah C.T.H., Huang J.W.J., Ng K.-P., Khaw S.L., Huang D.C.S., Ong S.T. (2016). The BIM deletion polymorphism: A paradigm of a permissive interaction between germline and acquired TKI resistance factors in chronic myeloid leukemia. Oncotarget 7 (3) : 2721-2733. ScholarBank@NUS Repository. https://doi.org/10.18632/oncotarget.5436; https://scholarbank.nus.edu.sg/handle/10635/174113

الاتاحة: https://scholarbank.nus.edu.sg/handle/10635/174113

المؤلفون: Chin, H.S., Egle, A., Khaw, S.L., Van Delft, M.F., Huang, D.C.

المصدر: European Journal of Cancer ; volume 69, page S110 ; ISSN 0959-8049

الاتاحة: http://dx.doi.org/10.1016/s0959-8049(16)32926-4
https://api.elsevier.com/content/article/PII:S0959804916329264?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S0959804916329264?httpAccept=text/xml

المؤلفون: Teng, T.L., Chu, Y.A., Chang, F.A., Chin, H.S.

المصدر: Cement and Concrete Composites ; volume 27, issue 4, page 481-492 ; ISSN 0958-9465

الاتاحة: http://dx.doi.org/10.1016/j.cemconcomp.2004.05.005
https://api.elsevier.com/content/article/PII:S0958946504001349?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0958946504001349?httpAccept=text/plain

المؤلفون: Bayen, S., Gong, Y., Chin, H.S., Lee, H.K., Leong, Y.E., Obbard, J.P.

المساهمون: CHEMISTRY, TROPICAL MARINE SCIENCE INSTITUTE, CHEMICAL & BIOMOLECULAR ENGINEERING

المصدر: Scopus

مصطلحات موضوعية: Androgen, Endocrine disruption, Estrogen, Green mussel, Heavy metals, Persistent organic pollutants, Reporter gene bioassay, Singapore

Relation: Bayen, S., Gong, Y., Chin, H.S., Lee, H.K., Leong, Y.E., Obbard, J.P. (2004-11). Androgenic and estrogenic response of green mussel extracts from Singapore's coastal environment using a human cell-based bioassay. Environmental Health Perspectives 112 (15) : 1467-1471. ScholarBank@NUS Repository. https://doi.org/10.1289/ehp.6990; http://scholarbank.nus.edu.sg/handle/10635/51752; 000224972500032

الاتاحة: http://scholarbank.nus.edu.sg/handle/10635/51752

المؤلفون: Chin, H.S., Goo, K.S., Sim, T.S.

المساهمون: MICROBIOLOGY, TROPICAL MARINE SCIENCE INSTITUTE

المصدر: Scopus

Relation: Chin, H.S., Goo, K.S., Sim, T.S. (2004). A Complete Library of Amino Acid Alterations at N304 in Streptomyces clavuligerus Deacetoxycephalosporin C Synthase Elucidates the Basis for Enhanced Penicillin Analogue Conversion. Applied and Environmental Microbiology 70 (1) : 607-609. ScholarBank@NUS Repository. https://doi.org/10.1128/AEM.70.1.607-609.2004; http://scholarbank.nus.edu.sg/handle/10635/31464; 000188115300077

الاتاحة: http://scholarbank.nus.edu.sg/handle/10635/31464

المؤلفون: Teng, T.L., Chu, Y.A., Chang, F.A., Chin, H.S.

المصدر: Computational Materials Science ; volume 31, issue 3-4, page 337-346 ; ISSN 0927-0256

الاتاحة: http://dx.doi.org/10.1016/j.commatsci.2004.04.003
https://api.elsevier.com/content/article/PII:S092702560400151X?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S092702560400151X?httpAccept=text/plain

المؤلفون: Chin, H.S., Sim, J., Seah, K.I., Sim, T.S.

المساهمون: MICROBIOLOGY

المصدر: Scopus

مصطلحات موضوعية: Acremonium chrysogenum, Deacetoxycephalosporin C synthase, Penicillin analogue, Streptomyces clavuligerus, Streptomyces jumonjinensis, art, hist

Relation: http://scholarbank.nus.edu.sg/handle/10635/31101

الاتاحة: http://scholarbank.nus.edu.sg/handle/10635/31101

المؤلفون: Sim, J., Wong, E., Chin, H.S., Sim, T.S.

المساهمون: MICROBIOLOGY

المصدر: Scopus

مصطلحات موضوعية: Conserved residues, Conserved structural modules, Hydrogen bonding network, Non-haem iron-dependent oxygenases and oxidases

Relation: http://scholarbank.nus.edu.sg/handle/10635/31097

الاتاحة: http://scholarbank.nus.edu.sg/handle/10635/31097

المؤلفون: Gong, Y., Chin, H.S., Obbard, J.P., Lim, L.S.E., Loy, C.J., Yong, E.L.

المساهمون: OBSTETRICS & GYNAECOLOGY, TROPICAL MARINE SCIENCE INSTITUTE, CHEMICAL & ENVIRONMENTAL ENGINEERING

المصدر: Scopus

مصطلحات موضوعية: Androgen, Endocrine disruptor, Estrogen, Reporter gene bioassay, Seawater, Singapore

Relation: Gong, Y., Chin, H.S., Obbard, J.P., Lim, L.S.E., Loy, C.J., Yong, E.L. (2003). Clustering of sex hormone disruptors in Singapore's marine environment. Environmental Health Perspectives 111 (12) : 1448-1453. ScholarBank@NUS Repository.; http://scholarbank.nus.edu.sg/handle/10635/37383; NOT_IN_WOS

الاتاحة: http://scholarbank.nus.edu.sg/handle/10635/37383

المؤلفون: Teng, T.L., Chu, Y.A., Chang, F.A., Chin, H.S., Lee, M.C.

المصدر: Annals of Nuclear Energy ; volume 30, issue 14, page 1473-1485 ; ISSN 0306-4549

الاتاحة: http://dx.doi.org/10.1016/s0306-4549(03)00080-x
https://api.elsevier.com/content/article/PII:S030645490300080X?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S030645490300080X?httpAccept=text/plain

المؤلفون: Chin, H.S., Sim, T.S.

المساهمون: TROPICAL MARINE SCIENCE INSTITUTE

المصدر: Scopus

مصطلحات موضوعية: C-terminus, Deacetoxycephalosporin C synthase, Penicillin analogue, Site-directed mutagenesis

Relation: Chin, H.S., Sim, T.S. (2002). C-terminus modification of Streptomyces clavuligerus deacetoxycephalosporin C synthase improves catalysis with an expanded substrate specificity. Biochemical and Biophysical Research Communications 295 (1) : 55-61. ScholarBank@NUS Repository. https://doi.org/10.1016/S0006-291X(02)00629-0; http://scholarbank.nus.edu.sg/handle/10635/110849; 000176815700010

الاتاحة: http://scholarbank.nus.edu.sg/handle/10635/110849

المؤلفون: Chin, H.S, Sim, T.S

المصدر: Biochemical and Biophysical Research Communications ; volume 295, issue 1, page 55-61 ; ISSN 0006-291X

الاتاحة: http://dx.doi.org/10.1016/s0006-291x(02)00629-0
https://api.elsevier.com/content/article/PII:S0006291X02006290?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0006291X02006290?httpAccept=text/plain

المؤلفون: Chin, H.S., Sim, J., Sim, T.S.

المساهمون: MICROBIOLOGY

المصدر: Scopus

مصطلحات موضوعية: Deacetoxycephalosporin C synthase, Isopenicillin N synthase, Penicillin analogue, Site-directed mutagenesis, Superimposition, hist, phil

Relation: http://scholarbank.nus.edu.sg/handle/10635/31017

الاتاحة: http://scholarbank.nus.edu.sg/handle/10635/31017

المؤلفون: Lin, S.S., Landesberg, R., Chin, H.S., Lin, J., Eisig, S.B., Lu, H.H.

المصدر: 2006 International Conference of the IEEE Engineering in Medicine & Biology Society; 2006, p4358-4361, 4p

المؤلفون: Chin, H.S., Goodge, J.W., Griffiths, R., Parish, D.J.

المصدر: IEEE Journal on Selected Areas in Communications; 1989, Vol. 7 Issue 5, p826-832, 7p

المؤلفون: Chin, H.S., Leach, M.J., Brown, M.J.

مصطلحات موضوعية: 32 ENERGY CONSERVATION, CONSUMPTION, AND UTILIZATION, SENSITIVITY ANALYSIS, URBAN AREAS, REGIONAL ANALYSIS, MATHEMATICAL MODELS

وصف الملف: application/pdf

Relation: http://www.osti.gov/servlets/purl/764066; https://www.osti.gov/biblio/764066

الاتاحة: http://www.osti.gov/servlets/purl/764066
https://www.osti.gov/biblio/764066

المؤلفون: Wang, W.J., Chin, H.S., Chang, C.S., Chuang, K.S., Lin, S.S.

المصدر: Synthetic Metals; June 1999, Vol. 103 Issue: 1-3 p2450-2451, 2p

المؤلفون: Kao, K.S.¹, Cheng, D.L.¹ dlcheng@mail.stu.edu, Chang, S.H.¹, Hsieh, P.T.², Chin, H.S.³, Lin, H.K.⁴

المصدر: Applied Surface Science. Oct2010, Vol. 256 Issue 24, p7446-7450. 5p.

مصطلحات موضوعية: *ZINC oxide thin films, *ELECTRIC properties of metallic films, *OPTICAL properties of metallic films, *LASER ablation, *MAGNETRON sputtering, *ELECTRIC conductivity