المؤلفون: Emergent BioSolutions

المصدر: A Phase 3 Safety and Immunogenicity Trial of the VLP-Based Chikungunya Virus Vaccine PXVX0317 in Adults ≥65 Years of Age
Bennett SR, McCarty JM, Ramanathan R, Mendy J, Richardson JS, Smith J, Alexander J, Ledgerwood JE, de Lame PA, Royalty Tredo S, Warfield KL, Bedell L. Safety and immunogenicity of PXVX0317, an aluminium hydroxide-adjuvanted chikungunya virus-like particle vaccine: a randomised, double-blind, parallel-group, phase 2 trial. Lancet Infect Dis. 2022 Sep;22(9):1343-1355. doi: 10.1016/S1473-3099(22)00226-2. Epub 2022 Jun 13.

المؤلفون: Weber, Whitney C, Streblow, Daniel N, Coffey, Lark L

المصدر: BioDrugs. 38(6)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Emerging Infectious Diseases, Vaccine Related, Infectious Diseases, Vector-Borne Diseases, Prevention, Arthritis, Biodefense, Biotechnology, Rare Diseases, Immunization, Orphan Drug, 3.4 Vaccines, 5.1 Pharmaceuticals, Infection, Good Health and Well Being, Humans, Chikungunya Fever, Chikungunya virus, Viral Vaccines, Vaccines, Attenuated, Animals, Vaccines, Virus-Like Particle, Drug Evaluation, Preclinical, Pharmacology and Pharmaceutical Sciences, Immunology, Pharmacology and pharmaceutical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/7jh1r3kv
https://escholarship.org/content/qt7jh1r3kv/qt7jh1r3kv.pdf

المؤلفون: Yao, Zhenlan, Ramachandran, Sangeetha, Huang, Serina, Kim, Erin, Jami-Alahmadi, Yasaman, Kaushal, Prashant, Bouhaddou, Mehdi, Wohlschlegel, James A, Li, Melody MH

المصدر: The EMBO Journal. 43(20)

مصطلحات موضوعية: Medical Microbiology, Biomedical and Clinical Sciences, Biological Sciences, Vector-Borne Diseases, Emerging Infectious Diseases, Infectious Diseases, Biodefense, 2.2 Factors relating to the physical environment, 2.1 Biological and endogenous factors, Infection, Good Health and Well Being, Chikungunya virus, Humans, Macrophages, Viral Envelope Proteins, Virion, Chikungunya Fever, Glycoproteins, Host-Pathogen Interactions, Virus Replication, THP-1 Cells, Alphavirus E1 Glycoprotein, Chikungunya Virus, eIF3k, Evolutionary Selection, Macrophage, Information and Computing Sciences, Medical and Health Sciences, Developmental Biology, Biological sciences, Biomedical and clinical sciences

وصف الملف: application/pdf

URL الوصول: https://escholarship.org/uc/item/0wz709h3
https://escholarship.org/content/qt0wz709h3/qt0wz709h3.pdf

المصدر: An Open-label Phase 3 Trial to Assess the Safety and Immunogenicity of a Live-attenuated Chikungunya Virus Vaccine (VLA1553) in Moderately Immunocompromised Adult Participants Infected with Human Immunodeficiency Virus

المؤلفون: National Institute of Allergy and Infectious Diseases (NIAID)

المصدر: A Double Blind, Randomized, Placebo-Controlled, Phase 1 Dose Escalation Trial to Evaluate the Safety and Immunogenicity of an Inactivated Chikungunya Virus Vaccine, HydroVax-005 CHIKV, in Healthy Adults

المصدر: Interest of Systematic Screening for Dengue, Chikungunya, and Zika, in Patients for Whom a Malaria Diagnosis is Negative, in the Event of a Recent Return From Travel: a Retrospective Study at the University Hospitals of Strasbourg, 2024-2025

المؤلفون: Walter Reed Army Institute of Research (WRAIR), Emergent BioSolutions

المصدر: A Phase 2 Open-label Study to Assess the Safety and Immunogenicity of an Alum-adjuvanted Chikungunya Virus-like Particle Vaccine (PXVX0317) in Prior Recipients of Other Alphavirus Vaccines Versus Alphavirus Naïve Controls.

المساهمون: Aileen Y Chang, Associate Professor of Medicine

المصدر: Methotrexate Treatment of Arthritis Caused by Chikungunya Virus (MARCH): A Phase III Randomized Controlled Clinical Trial of the Efficacy of Methotrexate Monotherapy in the Treatment of Chronic Arthritis After Chikungunya Infection

المصدر: A Phase 1, Randomized, Double-Blind, Multi-Site, Single Dose Escalation Study to Evaluate the Safety, Pharmacokinetics, and Immunogenicity of SAR440894 vs Placebo in Healthy Adults

المؤلفون: Universidad Autónoma de Yucatán, Emory University

المساهمون: Zhiyong Xi, Professor

المصدر: Testing a Combined Approach to Control Mosquito-Borne Diseases At Scale
Liang X, Tan CH, Sun Q, Zhang M, Wong PSJ, Li MI, Mak KW, Martin-Park A, Contreras-Perera Y, Puerta-Guardo H, Manrique-Saide P, Ng LC, Xi Z. Wolbachia wAlbB remains stable in Aedes aegypti over 15 years but exhibits genetic background-dependent variation in virus blocking. PNAS Nexus. 2022 Sep 22;1(4):pgac203. doi: 10.1093/pnasnexus/pgac203. eCollection 2022 Sep.
Lim JT, Bansal S, Chong CS, Dickens B, Ng Y, Deng L, Lee C, Tan LY, Chain G, Ma P, Sim S, Tan CH, Cook AR, Ng LC. Efficacy of Wolbachia-mediated sterility to reduce the incidence of dengue: a synthetic control study in Singapore. Lancet Microbe. 2024 May;5(5):e422-e432. doi: 10.1016/S2666-5247(23)00397-X. Epub 2024 Feb 8.
Martin-Park A, Che-Mendoza A, Contreras-Perera Y, Perez-Carrillo S, Puerta-Guardo H, Villegas-Chim J, Guillermo-May G, Medina-Barreiro A, Delfin-Gonzalez H, Mendez-Vales R, Vazquez-Narvaez S, Palacio-Vargas J, Correa-Morales F, Ayora-Talavera G, Pavia-Ruz N, Liang X, Fu P, Zhang D, Wang X, Toledo-Romani ME, Xi Z, Vazquez-Prokopec G, Manrique-Saide P. Pilot trial using mass field-releases of sterile males produced with the incompatible and sterile insect techniques as part of integrated Aedes aegypti control in Mexico. PLoS Negl Trop Dis. 2022 Apr 26;16(4):e0010324. doi: 10.1371/journal.pntd.0010324. eCollection 2022 Apr.
Zheng X, Zhang D, Li Y, Yang C, Wu Y, Liang X, Liang Y, Pan X, Hu L, Sun Q, Wang X, Wei Y, Zhu J, Qian W, Yan Z, Parker AG, Gilles JRL, Bourtzis K, Bouyer J, Tang M, Zheng B, Yu J, Liu J, Zhuang J, Hu Z, Zhang M, Gong JT, Hong XY, Zhang Z, Lin L, Liu Q, Hu Z, Wu Z, Baton LA, Hoffmann AA, Xi Z. Incompatible and sterile insect techniques combined eliminate mosquitoes. Nature. 2019 Aug;572(7767):56-61. doi: 10.1038/s41586-019-1407-9. Epub 2019 Jul 17.

المصدر: An Open-Label, Single Arm Trial To Evaluate Antibody Persistence And Long Term Safety Of A Live-Attenuated Chikungunya Virus Vaccine (VLA1553) In Adults Aged 18 Years and Above

المصدر: A Randomized, Observer-blinded, Dose Response Phase 2 Trial to Assess the Safety and Immunogenicity of Two Different Dose Levels of a Live-attenuated Chikungunya Virus Vaccine (VLA1553) in Healthy Children Aged 1 to 11 Years

المصدر: A Long-term Follow-up Study to Evaluate Safety and Immunogenicity of a Chikungunya Virus Virus-like Particle Vaccine (PXVX0317) in Healthy Adults and Adolescents After Either a Single or Booster Vaccination Dosing Regimen

المؤلفون: Emergent BioSolutions

المصدر: A Phase 3 Safety, Immunogenicity, and Lot-Consistency Trial of the VLP-Based Chikungunya Vaccine PXVX0317 in Healthy Adults and Adolescents
Bennett SR, McCarty JM, Ramanathan R, Mendy J, Richardson JS, Smith J, Alexander J, Ledgerwood JE, de Lame PA, Royalty Tredo S, Warfield KL, Bedell L. Safety and immunogenicity of PXVX0317, an aluminium hydroxide-adjuvanted chikungunya virus-like particle vaccine: a randomised, double-blind, parallel-group, phase 2 trial. Lancet Infect Dis. 2022 Sep;22(9):1343-1355. doi: 10.1016/S1473-3099(22)00226-2. Epub 2022 Jun 13.

المؤلفون: Göteborg University, Instituto Nacional de Salud, Colombia, Instituto Departamental de Salud de Norte de Santander, Universidad Francisco de Paula de Santander

المساهمون: Rocio Cardenas Sanchez, Researcher

المصدر: Control of Aedes Breeding Sites With a Dual-action Insecticidal Coating is Effective in Reducing Dengue Transmission: Cluster-randomised Controlled Trial Study
Carrillo MA, Cardenas R, Yanez J, Petzold M, Kroeger A. Risk of dengue, Zika, and chikungunya transmission in the metropolitan area of Cucuta, Colombia: cross-sectional analysis, baseline for a cluster-randomised controlled trial of a novel vector tool for water containers. BMC Public Health. 2023 May 30;23(1):1000. doi: 10.1186/s12889-023-15893-4.
Carrillo MA, Kroeger A, Cardenas Sanchez R, Diaz Monsalve S, Runge-Ranzinger S. The use of mobile phones for the prevention and control of arboviral diseases: a scoping review. BMC Public Health. 2021 Jan 9;21(1):110. doi: 10.1186/s12889-020-10126-4.
Cardenas R, Hussain-Alkhateeb L, Benitez-Valladares D, Sanchez-Tejeda G, Kroeger A. The Early Warning and Response System (EWARS-TDR) for dengue outbreaks: can it also be applied to chikungunya and Zika outbreak warning? BMC Infect Dis. 2022 Mar 7;22(1):235. doi: 10.1186/s12879-022-07197-6.
Wright E, Carrillo MA, Matamoros D, Sanchez RC, Yanez J, Di Lorenzo G, Villa JM, Kroeger A. Applicability of the Mexican ovitrap system for Aedes vector surveillance in Colombia. Pathog Glob Health. 2023 Sep;117(6):554-564. doi: 10.1080/20477724.2022.2146049. Epub 2022 Nov 16.
Hussain-Alkhateeb L, Rivera Ramirez T, Kroeger A, Gozzer E, Runge-Ranzinger S. Early warning systems (EWSs) for chikungunya, dengue, malaria, yellow fever, and Zika outbreaks: What is the evidence? A scoping review. PLoS Negl Trop Dis. 2021 Sep 16;15(9):e0009686. doi: 10.1371/journal.pntd.0009686. eCollection 2021 Sep.

المؤلفون: Valneva Austria GmbH

المصدر: A Multicenter, Randomized, Controlled, Double Blinded Pivotal Study to Evaluate Safety and Immunogenicity of a Live-attenuated Chikungunya Virus Vaccine Candidate (VLA1553) in Adolescents Aged 12 Years to <18 Years

المصدر: Investigating the Sylvatic Transmission and Reservoir Potential of Zika, Dengue, and Chikungunya Viruses of Co-located Humans and Long-tailed Macaques of Thailand and Cambodia
Bhatt S, Gething PW, Brady OJ, Messina JP, Farlow AW, Moyes CL, Drake JM, Brownstein JS, Hoen AG, Sankoh O, Myers MF, George DB, Jaenisch T, Wint GR, Simmons CP, Scott TW, Farrar JJ, Hay SI. The global distribution and burden of dengue. Nature. 2013 Apr 25;496(7446):504-7. doi: 10.1038/nature12060. Epub 2013 Apr 7.
Ruchusatsawat K, Wongjaroen P, Posanacharoen A, Rodriguez-Barraquer I, Sangkitporn S, Cummings DAT, Salje H. Long-term circulation of Zika virus in Thailand: an observational study. Lancet Infect Dis. 2019 Apr;19(4):439-446. doi: 10.1016/S1473-3099(18)30718-7. Epub 2019 Feb 27. Erratum In: Lancet Infect Dis. 2019 Apr;19(4):e109. doi: 10.1016/S1473-3099(19)30104-5.
Weaver SC, Lecuit M. Chikungunya virus and the global spread of a mosquito-borne disease. N Engl J Med. 2015 Mar 26;372(13):1231-9. doi: 10.1056/NEJMra1406035. No abstract available.

المؤلفون: Alysson Henrique Urbanski, Vanessa E. Maso, Felipe M. Martins, André Guilherme da Costa-Martins, Ana Paula B. do Nascimento Oliveira, Helder I. Nakaya

المصدر: Infectious Disease Reports, Vol 16, Iss 5, Pp 914-922 (2024)

مصطلحات موضوعية: chikungunya fever, rheumatoid arthritis, RANK signaling, CDR3, B cells, T cells, Other systems of medicine, RZ201-999

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2036-7449/16/5/73; https://doaj.org/toc/2036-7449

URL الوصول: https://doaj.org/article/35a1289a78f8464ebc72997c077298df

المصدر: Impact of Differential and Systematic Dengue, Chikungunya, and Malaria Diagnostics on Patient Management and Antibiotic Use in Burkina Faso and Ivory Coast

المصدر: Consequences of a Maternal-fetal Chikungunya Virus Infection. Neurocognitive and Sensory Assessment Around the Age of 13.