المؤلفون: Tatiana Erazo, Chiara M. Evans, Daniel Zakheim, Eren L. Chu, Alice Yunsi Refermat, Zahra Asgari, Xuejing Yang, Mariana Da Silva Ferreira, Sanjoy Mehta, Marco Vincenzo Russo, Andrea Knezevic, Xi-Ping Zhang, Zhengming Chen, Myles Fennell, Ralph Garippa, Venkatraman Seshan, Elisa de Stanchina, Olena Barbash, Connie Lee Batlevi, Christina S. Leslie, Ari M. Melnick, Anas Younes, Michael G. Kharas

المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/ae7897107ec04e2091ae2adabb8a333a

المؤلفون: Juliet O. Obi, Mulu Y. Lubula, Gabriel Cornilescu, Amy Henrickson, Kara McGuire, Chiara M. Evans, Margaret Phillips, Samuel P. Boyson, Borries Demeler, John L. Markley, Karen C. Glass

المصدر: Current Research in Structural Biology, Vol 2, Iss , Pp 104-115 (2020)

مصطلحات موضوعية: Bromodomain, Di-acetyllysine, Epigenetics, Histone, Post-translational modification, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2665928X20300106; https://doaj.org/toc/2665-928X

URL الوصول: https://doaj.org/article/373be060f02e4b3cb3c3da481b1aace9

المؤلفون: Chiara M. Evans, Margaret Phillips, Kiera L. Malone, Marco Tonelli, Gabriel Cornilescu, Claudia Cornilescu, Simon J. Holton, Mátyás Gorjánácz, Liping Wang, Samuel Carlson, Jamie C. Gay, Jay C. Nix, Borries Demeler, John L. Markley, Karen C. Glass

المصدر: International Journal of Molecular Sciences; Volume 22; Issue 17; Pages: 9128

مصطلحات موضوعية: ATAD2 bromodomain, acetylated histones, post-translational modifications, X-ray crystallography, nuclear magnetic resonance, isothermal titration calorimetry, analytical ultracentrifugation, chromatin reader domain, cancer, epigenetics

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Biochemistry; https://dx.doi.org/10.3390/ijms22179128

الاتاحة: https://doi.org/10.3390/ijms22179128

المؤلفون: Coraline Mlynarczyk, Matt Teater, Juhee Pae, Christopher R. Chin, Ling Wang, Theinmozhi Arulraj, Darko Barisic, Antonin Papin, Kenneth B. Hoehn, Ekaterina Kots, Jonatan Ersching, Arnab Bandyopadhyay, Ersilia Barin, Hui Xian Poh, Chiara M. Evans, Amy Chadburn, Zhengming Chen, Hao Shen, Hannah M. Isles, Benedikt Pelzer, Ioanna Tsialta, Ashley S. Doane, Huimin Geng, Muhammad Hassan Rehman, Jonah Melnick, Wyatt Morgan, Diu T. T. Nguyen, Olivier Elemento, Michael G. Kharas, Samie R. Jaffrey, David W. Scott, George Khelashvili, Michael Meyer-Hermann, Gabriel D. Victora, Ari Melnick

المصدر: Science. 379

مصطلحات موضوعية: Multidisciplinary

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::89af1728240b964263f280725c1cf48f
https://doi.org/10.1126/science.abj7412

المؤلفون: Jonathan T. Lloyd, Kyle McLaughlin, Mulu Y. Lubula, Jamie C. Gay, Andrea Dest, Cong Gao, Margaret Phillips, Marco Tonelli, Gabriel Cornilescu, Matthew R. Marunde, Chiara M. Evans, Samuel P. Boyson, Samuel Carlson, Michael-Christopher Keogh, John L. Markley, Seth Frietze, Karen C. Glass

المصدر: J Med Chem

مصطلحات موضوعية: ATPase, Computational biology, Molecular Dynamics Simulation, medicine.disease_cause, Crystallography, X-Ray, Article, Histones, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Molecular recognition, Protein Domains, Drug Discovery, medicine, Humans, Amino Acid Sequence, Nuclear protein, Loss function, 030304 developmental biology, 0303 health sciences, Binding Sites, biology, Ligand, Chemistry, Alternative splicing, Isothermal titration calorimetry, Acetylation, Ligand (biochemistry), Recombinant Proteins, Cell biology, Chromatin, Bromodomain, DNA-Binding Proteins, Alternative Splicing, Histone, 030220 oncology & carcinogenesis, Acetyllysine, Mutagenesis, Site-Directed, biology.protein, ATPases Associated with Diverse Cellular Activities, Molecular Medicine, Carcinogenesis, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8961c303018439c9f7b6ef608f6fb1de
https://doi.org/10.1021/acs.jmedchem.0c01178

المؤلفون: Karen C. Glass, Cameron Montgomery, Jonathan T. Lloyd, Kyle McLaughlin, Matthew R. Marunde, Chiara M. Evans, Samuel P. Boyson, Michael‐Christopher Keogh, Seth Frietze

المصدر: The FASEB Journal. 36

مصطلحات موضوعية: Genetics, Molecular Biology, Biochemistry, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2e82c9b73f62936c1df5f92796891fe4
https://doi.org/10.1096/fasebj.2022.36.s1.0r269

المؤلفون: Tatiana Erazo, Chiara M. Evans, Daniel Zakheim, Karen L. Chu, Alice Yunsi Refermat, Zahra Asgari, Xuejing Yang, Mariana Da Silva Ferreira, Sanjoy Mehta, Marco Vincenzo Russo, Andrea Knezevic, Xi-Ping Zhang, Zhengming Chen, Myles Fennell, Ralph Garippa, Venkatraman Seshan, Elisa de Stanchina, Olena Barbash, Connie Lee Batlevi, Christina S. Leslie, Ari M. Melnick, Anas Younes, Michael G. Kharas

المصدر: Nature communications. 13(1)

مصطلحات موضوعية: Protein-Arginine N-Methyltransferases, Multidisciplinary, Lymphoma, B-Cell, Lymphoma, Proto-Oncogene Proteins c-bcl-2, Cell Line, Tumor, Mutation, General Physics and Astronomy, Humans, RNA-Binding Proteins, General Chemistry, Tumor Suppressor Protein p53, General Biochemistry, Genetics and Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be7e429b6aac6d3fecd6a10f5b0a27b5
https://pubmed.ncbi.nlm.nih.gov/36167829

المؤلفون: Mulu Y. Lubula, Margaret Phillips, Gabriel Cornilescu, Juliet O. Obi, Karen C. Glass, Samuel P. Boyson, John L. Markley, Amy Henrickson, Chiara M. Evans, Kara McGuire, Borries Demeler

المصدر: Current Research in Structural Biology, Vol 2, Iss, Pp 104-115 (2020)
Curr Res Struct Biol

مصطلحات موضوعية: Bromodomain, Article, Histone H4, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Di-acetyllysine, Structural Biology, Epigenetics, Molecular Biology, lcsh:QH301-705.5, 030304 developmental biology, 0303 health sciences, biology, Chemistry, Methylation, Histone acetyltransferase, Chromatin, Cell biology, Histone, lcsh:Biology (General), Acetylation, 030220 oncology & carcinogenesis, Acetyllysine, biology.protein, Post-translational modification

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89bf6d9c227e0c9391b055a21403786e
http://www.sciencedirect.com/science/article/pii/S2665928X20300106

المؤلفون: Juliet O. Obi, Keiko Maekawa, Karen C. Glass, Sonia Parikh, Qinghai Zhang, Manish B. Shah, Chiara M. Evans

المصدر: Mol Pharmacol

مصطلحات موضوعية: 0301 basic medicine, Arginine, Polymorphism, Single Nucleotide, Losartan, 03 medical and health sciences, 0302 clinical medicine, Catalytic Domain, medicine, Humans, Binding site, CYP2C9, Alleles, Antihypertensive Agents, Cytochrome P-450 CYP2C9, Pharmacology, chemistry.chemical_classification, biology, Chemistry, Active site, Isothermal titration calorimetry, Articles, Amino acid, 030104 developmental biology, Biochemistry, biology.protein, Molecular Medicine, 030217 neurology & neurosurgery, Drug metabolism, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8be8903328728f0b4607f43f474fb85c
https://pubmed.ncbi.nlm.nih.gov/32938720

المؤلفون: Jamie C. Gay, Brian E. Eckenroth, Chiara M. Evans, Cassiano Langini, Samuel Carlson, Jonathan T. Lloyd, Amedeo Caflisch, Karen C. Glass

المساهمون: University of Zurich, Glass, Karen C

المصدر: Proteins: Structure, Function, and Bioinformatics. 87:157-167

مصطلحات موضوعية: 1303 Biochemistry, 610 Medicine & health, Plasma protein binding, Molecular Dynamics Simulation, Crystallography, X-Ray, Ligands, Biochemistry, Article, Histones, 03 medical and health sciences, chemistry.chemical_compound, 1315 Structural Biology, Protein Domains, Structural Biology, 10019 Department of Biochemistry, 1312 Molecular Biology, Humans, Nucleosome, Cysteine, Disulfides, Molecular Biology, 030304 developmental biology, Adenosine Triphosphatases, 0303 health sciences, Chemistry, Lysine, 030302 biochemistry & molecular biology, Isothermal titration calorimetry, Ligand (biochemistry), Small molecule, Bromodomain, DNA-Binding Proteins, Solubility, Mutation, Acetyllysine, Biophysics, ATPases Associated with Diverse Cellular Activities, Thermodynamics, 570 Life sciences, biology, Protein Binding

وصف الملف: Gay_et_al-2019-Proteins__Structure,_Function,_and_Bioinformatics.pdf - application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f35063896386cbdc18f1b78624ed60e
https://doi.org/10.1002/prot.25636

المؤلفون: Alice Yunsi Refermat, Olena Barbash, Connie Lee Batlevi, Michael G. Kharas, Ingrid Tatiana Erazo, Karen L Chu, Anas Younes, Daniel Zakheim, Chiara M Evans

المصدر: Blood. 138:788-788

مصطلحات موضوعية: medicine.medical_treatment, Protein arginine methyltransferase 5, Immunology, RNA-binding protein, Cell Biology, Hematology, Biology, Tp53 mutation, medicine.disease, Biochemistry, Targeted therapy, medicine, Cancer research, B-cell lymphoma

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1e8e6cfa9412f0ceee41d09e8d91b099
https://doi.org/10.1182/blood-2021-151280

المؤلفون: Jamie C. Gay, Brian E. Eckenroth, Chiara M. Evans, Cassiano Langini, Samuel Carlson, Jonathan T. Lloyd, Amedeo Caflisch, Karen C. Glass

المصدر: Proteins: Structure, Function, and Bioinformatics. 87:C4-C4

مصطلحات موضوعية: Structural Biology, Molecular Biology, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::23b1a281b008eb04d68cd0f5ca8b38ea
https://doi.org/10.1002/prot.25660