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1Academic Journal
المصدر: ACS Omega, Vol 3, Iss 10, Pp 13313-13322 (2018)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2470-1343
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2Academic Journal
المصدر: International Journal of Molecular Sciences, Vol 20, Iss 22, p 5538 (2019)
مصطلحات موضوعية: ire1, kira, dimer formation, unfolded protein response, protein–protein docking, molecular dynamics simulations, Biology (General), QH301-705.5, Chemistry, QD1-999
Relation: https://www.mdpi.com/1422-0067/20/22/5538; https://doaj.org/toc/1422-0067; https://doaj.org/article/9ff34e13bd1d4625b85a2f936af53667
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المؤلفون: Chetan Chintha, Joe W. Ramos, Won Seok Yang, Afshin Samali, Liam Morrison, Leila Tabrizi, Andrea Erxleben
المصدر: European Journal of Inorganic Chemistry
مصطلحات موضوعية: Full Paper, biology, Chemistry, Ligand, Stereochemistry, medicine.drug_class, Cytotoxicity, Translocator proteins, Thioredoxin reductase, Carboxamide, Full Papers, Inorganic Chemistry, chemistry.chemical_compound, Docking (molecular), Quinazoline, Translocator protein, biology.protein, medicine, Gold, Binding site, Triphenylphosphine, Alkynyl ligands
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4
المؤلفون: Andrea Erxleben, Chetan Chintha, Adrienne M. Gorman, Kerry Thompson, Afshin Samali, Katarzyna Mnich, Liam Morrison, Leila Tabrizi, Noel F. Lowndes, Janna Luessing, Peter Dockery
المصدر: Molecular Pharmaceutics. 17:3009-3023
مصطلحات موضوعية: Organoplatinum Compounds, Cell Survival, Stereochemistry, DNA damage, Pharmaceutical Science, Antineoplastic Agents, 02 engineering and technology, Ligands, 030226 pharmacology & pharmacy, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Drug Discovery, medicine, Translocator protein, Humans, Prodrugs, Binding site, Inner mitochondrial membrane, Cisplatin, biology, Ligand, Chemistry, Epithelial Cells, Biological activity, Prodrug, 021001 nanoscience & nanotechnology, Mitochondria, Oxaliplatin, Mitochondrial Membranes, MCF-7 Cells, biology.protein, Molecular Medicine, Reactive Oxygen Species, 0210 nano-technology, DNA Damage, medicine.drug
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5
المصدر: RSC Advances
مصطلحات موضوعية: endocrine system, 0303 health sciences, 010304 chemical physics, Molecular model, Chemistry, Kinase, General Chemical Engineering, In silico, General Chemistry, 01 natural sciences, Small molecule, 3. Good health, 03 medical and health sciences, RIPK1, Docking (molecular), 0103 physical sciences, Biophysics, PERK inhibitors, Binding site, 030304 developmental biology
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المؤلفون: Chetan Chintha, Dimitrios Doultsinos, Adrienne W. Paton, Antonio Carlesso, Leif A. Eriksson, James C. Paton, Afshin Samali, Eric Chevet
المساهمون: Chemistry, Oncogenesis, Stress and Signaling (COSS), Université de Rennes (UR)-CRLCC Eugène Marquis (CRLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre Eugène Marquis (CRLCC), University of Gothenburg (GU), National University of Ireland [Galway] (NUI Galway), University of Adelaide, Fondation pour la Recherche Médicale, 2014‐3914, Agence Nationale de la Recherche, Institut National Du Cancer, 2014‐3914, Vetenskapsrådet, ANR-17-RAR3-0003,ERAAT,Enhancing Endoplasmic Reticulum Proteostasis to Rescue Alpha1 Antitrypsin Deficiency(2017), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-CRLCC Eugène Marquis (CRLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Jonchère, Laurent, Enhancing Endoplasmic Reticulum Proteostasis to Rescue Alpha1 Antitrypsin Deficiency - - ERAAT2017 - ANR-17-RAR3-0003 - E-RARE - VALID
المصدر: FEBS Journal
FEBS Journal, 2021, 288 (3), pp.945-960. ⟨10.1111/febs.15372⟩
FEBS Journal, Wiley, 2021, 288 (3), pp.945-960. ⟨10.1111/febs.15372⟩
The FEBS Journalمصطلحات موضوعية: 0301 basic medicine, Peptidomimetic, Leucovorin, Cefoperazone, [SDV.CAN]Life Sciences [q-bio]/Cancer, IRE1, Protein Serine-Threonine Kinases, Endoplasmic Reticulum, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Protein Domains, [SDV.CAN] Life Sciences [q-bio]/Cancer, Cell Line, Tumor, Endoribonucleases, medicine, Humans, Enzyme Inhibitors, Drug Approval, Molecular Biology, Fludarabine Phosphate, Temozolomide, Molecular Structure, United States Food and Drug Administration, Chemistry, Kinase, Inhibitors, Endoplasmic reticulum, glioblastoma, Cell Biology, Endoplasmic Reticulum Stress, United States, 3. Good health, Methotrexate, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, Unfolded protein response, Unfolded Protein Response, Peptidomimetics, Pharmacophore, Vidarabine Phosphate, Protein Binding, Signal Transduction, medicine.drug
وصف الملف: application/pdf
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المؤلفون: Michael Huber, Leif A. Eriksson, Chetan Chintha, Afshin Samali, Akram Obiedat, Thomas Schubert, Eric Chevet, Weiss Sadan Tommy, Thomas Wilhelm, Mohamed Mahameed, Boaz Tirosh, Odai Darawshi
المساهمون: The Hebrew University of Jerusalem (HUJ), RWTH Aachen University, National University of Ireland [Galway] (NUI Galway), 2bind GmbH [Regensburg, Germany], Chemistry, Oncogenesis, Stress and Signaling (COSS), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-CRLCC Eugène Marquis (CRLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM), CRLCC Eugène Marquis (CRLCC), University of Gothenburg (GU), Rheinisch-Westfälische Technische Hochschule Aachen University (RWTH), Université de Rennes (UR)-CRLCC Eugène Marquis (CRLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Jonchère, Laurent
المصدر: Cell Death and Disease
Cell Death and Disease, Nature Publishing Group, 2019, 10 (4), pp.300. ⟨10.1038/s41419-019-1523-3⟩
Cell Death & Disease
Cell Death and Disease, Vol 10, Iss 4, Pp 1-12 (2019)
Cell Death and Disease, 2019, 10 (4), pp.300. ⟨10.1038/s41419-019-1523-3⟩مصطلحات موضوعية: 0301 basic medicine, Cancer Research, endocrine system, Indoles, Cell Survival, Immunology, [SDV.CAN]Life Sciences [q-bio]/Cancer, Naphthalenes, Endocytosis, Receptor tyrosine kinase, Article, 03 medical and health sciences, Cellular and Molecular Neuroscience, eIF-2 Kinase, 0302 clinical medicine, [SDV.CAN] Life Sciences [q-bio]/Cancer, Humans, Kinase activity, lcsh:QH573-671, biology, Kinase, Chemistry, ATF6, lcsh:Cytology, Adenine, Imidazoles, Cell Biology, Hep G2 Cells, Molecular biology, Kinetics, Proto-Oncogene Proteins c-kit, 030104 developmental biology, HEK293 Cells, Cell culture, 030220 oncology & carcinogenesis, Pyrazines, Unfolded protein response, biology.protein, Unfolded Protein Response, Lysosomes, Tyrosine kinase
وصف الملف: application/pdf
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المؤلفون: Aitor Almanza, Antonio Carlesso, Chetan Chintha, Stuart Creedican, Dimitrios Doultsinos, Brian Leuzzi, Andreia Luís, Nicole McCarthy, Luigi Montibeller, Sanket More, Alexandra Papaioannou, Franziska Püschel, Maria Livia Sassano, Josip Skoko, Patrizia Agostinis, Jackie de Belleroche, Leif A. Eriksson, Simone Fulda, Adrienne M. Gorman, Sandra Healy, Andrey Kozlov, Cristina Muñoz-Pinedo, Markus Re
المصدر: The FEBS Journal
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9
المؤلفون: Manjunath A. Hurakadli, Jayaprakash Periasamy, Vijay Potluri, Muralidhara Padigaru, Mamatha B. Nijaguna, Sanjana Boggaram, Gayathri Sadasivam, Lokavya Meenakshi Kurup, Ashok R. Venkitaraman, Dhruv Raina, Kavitha Bharatham, Subbarao Jasti, Aneesh Goyal, Vadiraj Kurdekar, Kavyashree Manjunath, Chetan Chintha
المساهمون: Raina, Dhruv [0000-0003-4140-3925], Manjunath, Kavyashree [0000-0002-1838-5362], Apollo - University of Cambridge Repository
المصدر: Cell Chemical Biology
مصطلحات موضوعية: 0301 basic medicine, Phosphopeptides, DNA damage, Cell Survival, Clinical Biochemistry, RAD51, Biology, Molecular Dynamics Simulation, DNA damage response, Biochemistry, Article, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Protein Domains, Drug Discovery, Recombinase, Fluorescence Resonance Energy Transfer, Humans, lead discovery, Molecular Biology, Cells, Cultured, Pharmacology, BRCT domain, Molecular Structure, Phosphopeptide, BRCA1 Protein, structure-activity relationship, BRCA1, Cell biology, MDC1, 030104 developmental biology, Förster resonance energy transfer, HEK293 Cells, chemistry, 030220 oncology & carcinogenesis, Molecular Medicine, drug-like inhibitor, DNA, Signal Transduction
وصف الملف: application/pdf
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10
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11
المؤلفون: Vivek K. Vyas, Chetan Chintha, Nirzari Gupta, Manjunath Ghate
المصدر: Medicinal Chemistry Research. 23:1189-1201
مصطلحات موضوعية: Chemistry, Docking (molecular), Organic Chemistry, Protein Data Bank (RCSB PDB), Druggability, Signal transducing adaptor protein, MODELLER, Homology modeling, Computational biology, General Pharmacology, Toxicology and Pharmaceutics, Binding site, Molecular biology, G protein-coupled receptor
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12
المؤلفون: Paresh K. Patel, Chetan Chintha, Manjunath Ghate, Vivek K. Vyas
المصدر: Current Computer Aided-Drug Design. 9:433-445
مصطلحات موضوعية: Benzimidazole, Quantitative structure–activity relationship, Training set, Loo, Correlation coefficient, Chemistry, medicine.drug_class, Stereochemistry, General Medicine, Receptor antagonist, Angiotensin II, chemistry.chemical_compound, Drug Discovery, Lipophilicity, medicine, Molecular Medicine
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13
المؤلفون: Hardik G. Bhatt, J. Jalu, Nirzari Gupta, Chetan Chintha, Manjunath Ghate, Vivek K. Vyas, Paresh K. Patel
المصدر: SAR and QSAR in Environmental Research. 24:519-551
مصطلحات موضوعية: Quantitative structure–activity relationship, Molecular Structure, Chemistry, Stereochemistry, Aryl, Quantitative Structure-Activity Relationship, Bioengineering, General Medicine, chemistry.chemical_compound, Glucosides, Glucoside, Drug Discovery, Hypoglycemic Agents, Molecular Medicine, Enzyme Inhibitors, Sodium-Glucose Transporter 2 Inhibitors, Cambridge Mathematical Tripos
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14
المؤلفون: Karolina Pakos-Zebrucka, Adrienne M. Gorman, Chetan Chintha, Eric Chevet, Afshin Samali, Katarzyna Mnich
المصدر: Encyclopedia of Signaling Molecules ISBN: 9781461464389
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15
المؤلفون: Vivek K, Vyas, Manjunath, Ghate, Chetan, Chintha, Paresh, Patel
المصدر: Current computer-aided drug design. 9(3)
مصطلحات موضوعية: Models, Molecular, Angiotensin II, Humans, Quantitative Structure-Activity Relationship, Benzimidazoles, Angiotensin II Type 1 Receptor Blockers, Receptor, Angiotensin, Type 1
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16
المؤلفون: Chetan Chintha, Mitul R. Pandya, Vivek K. Vyas
المصدر: Anti-cancer agents in medicinal chemistry. 13(3)
مصطلحات موضوعية: Cancer Research, Programmed cell death, medicine.drug_class, Genetic enhancement, Antineoplastic Agents, Apoptosis, Mitochondrion, Biology, Monoclonal antibody, Small Molecule Libraries, Neoplasms, medicine, Humans, Pharmacology, Mechanism (biology), Cancer, Antibodies, Monoclonal, Receptors, Death Domain, Oligonucleotides, Antisense, medicine.disease, Recombinant Proteins, Cell biology, Mitochondria, Gene Expression Regulation, Neoplastic, Drug Resistance, Neoplasm, Drug Design, Cancer cell, Molecular Medicine, Apoptosis Regulatory Proteins, Signal Transduction
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17
المؤلفون: Vivek K. Vyas, Chetan Chintha, Manjunath Ghate, Ravi Ukawala
المصدر: Indian Journal of Pharmaceutical Sciences
مصطلحات موضوعية: ligand design, model validation, Drug discovery, homology modeling, Pharmaceutical Science, Nanotechnology, Review Article, Computational biology, Protein structure prediction, Biology, GPCRs, loop structure prediction, Structural genomics, Protein fragment library, Protein structure, Structural biology, sequence alignment, Homology modeling, Loop modeling, Threading (protein sequence)
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