المؤلفون: Tan A., Babak M. V., Venkatesan G., Lim C., Klotz K. -N., Herr D. R., Cheong S. L., Federico S., Spalluto G., Ong W. -Y., Chen Y. Z., Loo J. S. E., Pastori G.

المساهمون: Tan, A., Babak, M. V., Venkatesan, G., Lim, C., Klotz, K. -N., Herr, D. R., Cheong, S. L., Federico, S., Spalluto, G., Ong, W. -Y., Chen, Y. Z., Loo, J. S. E., Pastori, G.

مصطلحات موضوعية: Gastrointestinal cancer, HA, AR, Indolylpyrimidylpiperazine, Partial agonists

Time: 3

وصف الملف: ELETTRONICO

Relation: info:eu-repo/semantics/altIdentifier/pmid/31614517; info:eu-repo/semantics/altIdentifier/wos/WOS:000496249500030; volume:24; issue:20; firstpage:1; lastpage:16; numberofpages:16; journal:MOLECULES; http://hdl.handle.net/11368/2954606; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85073481666; https://www.mdpi.com/1420-3049/24/20/3661

الاتاحة: http://hdl.handle.net/11368/2954606
https://doi.org/10.3390/molecules24203661
https://www.mdpi.com/1420-3049/24/20/3661

المؤلفون: Cheong, S. L., Yau, S. L., Silva, G., Coelho, R.

المصدر: Clinical and Experimental Dermatology ; volume 46, issue 7, page 1338-1340 ; ISSN 0307-6938 1365-2230

مصطلحات موضوعية: Dermatology

الاتاحة: http://dx.doi.org/10.1111/ced.14719
https://onlinelibrary.wiley.com/doi/pdf/10.1111/ced.14719
https://onlinelibrary.wiley.com/doi/full-xml/10.1111/ced.14719

المؤلفون: Venkatesan, G, Paira, P., Cheong, S. L., Klotz, K. N., Pastorin, G., FEDERICO, STEPHANIE, SPALLUTO, GIAMPIERO

المساهمون: Venkatesan, G, Paira, P., Cheong, S. L., Federico, Stephanie, Klotz, K. N., Spalluto, Giampiero, Pastorin, G.

مصطلحات موضوعية: 4-d]pyrimidine, Adenosine receptor antagonist, Carboxylate derivative, Homology modeling, Molecular docking, Pyrazolo[3, Structure-affinity relationship, Drug Discovery3003 Pharmaceutical Science, Organic Chemistry, Pharmacology

وصف الملف: STAMPA

Relation: info:eu-repo/semantics/altIdentifier/pmid/25633494; info:eu-repo/semantics/altIdentifier/wos/WOS:000350919100066; volume:2015; issue:92; firstpage:784; lastpage:798; numberofpages:15; journal:EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY; http://hdl.handle.net/11368/2835190; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84921653076; http://www.sciencedirect.com/science/article/pii/S0223523415000665

الاتاحة: http://hdl.handle.net/11368/2835190
https://doi.org/10.1016/j.ejmech.2015.01.046
http://www.sciencedirect.com/science/article/pii/S0223523415000665

المؤلفون: Cheong S. L., Venkatesan G., Mandel L., Shao Y. M., Moro S., Pastorin G., FEDERICO, STEPHANIE, SPALLUTO, GIAMPIERO

المساهمون: Cheong, S. L., Federico, Stephanie, Venkatesan, G., Mandel, L., Shao, Y. M., Moro, S., Spalluto, Giampiero, Pastorin, G.

مصطلحات موضوعية: pharmacology, agonist, antagonist

وصف الملف: STAMPA

Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:000315102500001; volume:33; issue:2; firstpage:235; lastpage:335; numberofpages:101; journal:MEDICINAL RESEARCH REVIEWS; http://hdl.handle.net/11368/2403685; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-84873985958

الاتاحة: http://hdl.handle.net/11368/2403685
https://doi.org/10.1002/med.20254

المؤلفون: FEDERICO, STEPHANIE, SPALLUTO, GIAMPIERO, Paoletta S., Cheong S. L., Pastorin G., Cacciari B., Stragliotto S., Klotz, K. N., Siegel J., Gao Z. G., Jacobson K. A., Moro S.

المساهمون: Federico, Stephanie, Paoletta, S., Cheong, S. L., Pastorin, G., Cacciari, B., Stragliotto, S., Klotz, K. N., Siegel, J., Gao, Z. G., Jacobson, K. A., Moro, S., Spalluto, Giampiero

مصطلحات موضوعية: high affinity, ligand recognition, adenosine

وصف الملف: STAMPA

Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:000286798100016; volume:54/2011; firstpage:877; lastpage:889; journal:JOURNAL OF MEDICINAL CHEMISTRY; http://hdl.handle.net/11368/2403684; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-79851495268

الاتاحة: http://hdl.handle.net/11368/2403684
https://doi.org/10.1021/jm101349u

المؤلفون: Cheong S. L., Venkatesan G., Paira P., Jothibasu R., Mandel A. L., Pastorin G., FEDERICO, STEPHANIE, SPALLUTO, GIAMPIERO

المساهمون: Cheong, S. L., Venkatesan, G., Paira, P., Jothibasu, R., Mandel, A. L., Federico, Stephanie, Spalluto, Giampiero, Pastorin, G.

مصطلحات موضوعية: Adenosine receptor, Pyrazole, GPCR, antagonists

وصف الملف: ELETTRONICO

Relation: volume:2011; firstpage:1; lastpage:15; numberofpages:15; journal:INTERNATIONAL JOURNAL OF MEDICINAL CHEMISTRY; http://hdl.handle.net/11368/2637238

الاتاحة: http://hdl.handle.net/11368/2637238
https://doi.org/10.1155/2011/480652

المؤلفون: Cheong S. L., Venkatesan G., Paira P., Shao Y. M., Yap C. W., Pastorin G., FEDERICO, STEPHANIE, SPALLUTO, GIAMPIERO

المساهمون: Cheong, S. L., Federico, Stephanie, Venkatesan, G., Paira, P., Shao, Y. M., Spalluto, Giampiero, Yap, C. W., Pastorin, G.

مصطلحات موضوعية: QSAR, CoMFA

وصف الملف: STAMPA

Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:000290024200022; volume:21/2011; firstpage:2898; lastpage:2905; journal:BIOORGANIC & MEDICINAL CHEMISTRY LETTERS; http://hdl.handle.net/11368/2403683

الاتاحة: http://hdl.handle.net/11368/2403683
https://doi.org/10.1016/j.bmcl.2011.03.073

المؤلفون: Cheong S. L., Dolzhenko A. V., Paoletta S., Lee E. P. R., Kachler S., Klotz, K. N., Moro, S., Pastorin, G., FEDERICO, STEPHANIE, SPALLUTO, GIAMPIERO

المساهمون: Cheong, S. L., Dolzhenko, A. V., Paoletta, S., Lee, E. P. R., Kachler, S., Federico, Stephanie, Klotz, K. N., Spalluto, Giampiero, Moro, S., Pastorin, G.

مصطلحات موضوعية: Structure-affinity relationship, affinity, selectivity

وصف الملف: STAMPA

Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:000295494600021; volume:19/2011; firstpage:6120; lastpage:6134; journal:BIOORGANIC & MEDICINAL CHEMISTRY; http://hdl.handle.net/11368/2403682; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-80053237248

الاتاحة: http://hdl.handle.net/11368/2403682
https://doi.org/10.1016/j.bmc.2011.08.026

المؤلفون: Cheong S. L., Dolzhenko A., Kachler S., Paoletta S., Cacciari B., Klotz K. N., Moro S., Pastorin G., FEDERICO, STEPHANIE, SPALLUTO, GIAMPIERO

المساهمون: Cheong, S. L., Dolzhenko, A., Kachler, S., Paoletta, S., Federico, Stephanie, Cacciari, B., Klotz, K. N., Moro, S., Spalluto, Giampiero, Pastorin, G.

مصطلحات موضوعية: adenosine, receptor, antagonists

وصف الملف: STAMPA

Relation: info:eu-repo/semantics/altIdentifier/wos/WOS:000276562400030; volume:53; firstpage:3361; lastpage:3375; journal:JOURNAL OF MEDICINAL CHEMISTRY; http://hdl.handle.net/11368/2303744; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-77951105392

الاتاحة: http://hdl.handle.net/11368/2303744
https://doi.org/10.1021/jm100049f

المؤلفون: Cheong, S. L., Dolzhenko, A., Kachler, S., Paoletta, S., Federico, S., Cacciari, Barbara, Klotz, K. N., Moro, S., Spalluto, G. Pastorin G.

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______3709::9fc8ec2cdc8ac22b2bd9bf2356c0fb3a
http://hdl.handle.net/11392/1529346

المؤلفون: Maria V. Babak, Giampiero Spalluto, Wei-Yi Ong, Aaron Tan, Siew Lee Cheong, Giorgia Pastorin, Clarissa Lim, Yu Zong Chen, Karl-Norbert Klotz, Deron R. Herr, Jason S. E. Loo, Stephanie Federico, Gopalakrishnan Venkatesan

المساهمون: Tan, A., Babak, M. V., Venkatesan, G., Lim, C., Klotz, K. -N., Herr, D. R., Cheong, S. L., Federico, S., Spalluto, G., Ong, W. -Y., Chen, Y. Z., Loo, J. S. E., Pastori, G.

المصدر: Molecules
Molecules, Vol 24, Iss 20, p 3661 (2019)

مصطلحات موضوعية: Models, Molecular, Indoles, Tertiary amine, HA, Pharmaceutical Science, Pharmacology, Analytical Chemistry, 0302 clinical medicine, Cricetinae, Drug Discovery, Receptor, Cytotoxicity, Gastrointestinal Neoplasms, Indolylpyrimidylpiperazine, 0303 health sciences, Chemistry, Communication, Ligand (biochemistry), Adenosine A2 Receptor Antagonists, Chemistry (miscellaneous), 030220 oncology & carcinogenesis, Molecular Medicine, ha3ar, Receptor, Adenosine A2A, hA3AR, Indolylpyrimidylpiperazines, CHO Cells, Pyrimidinones, Partial agonists, Partial agonist, lcsh:QD241-441, 03 medical and health sciences, Structure-Activity Relationship, Gastrointestinal cancer, Cricetulus, lcsh:Organic chemistry, Structure–activity relationship, Animals, Humans, ddc:610, Physical and Theoretical Chemistry, Piperazine, Binding selectivity, 030304 developmental biology, Cell Proliferation, Organic Chemistry, Receptor, Adenosine A3, Adenosine receptor, 3, AR

وصف الملف: application/pdf; ELETTRONICO

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f14bceec5f55b21302d334a3c747c2
http://hdl.handle.net/11368/2954606

المؤلفون: Siew Lee Cheong, Stephanie Federico, Gopalakrishnan Venkatesan, Giampiero Spalluto, Priyankar Paira, Karl-Norbert Klotz, Giorgia Pastorin

المساهمون: Venkatesan, G, Paira, P., Cheong, S. L., Federico, Stephanie, Klotz, K. N., Spalluto, Giampiero, Pastorin, G.

المصدر: European journal of medicinal chemistry. 92

مصطلحات موضوعية: Models, Molecular, Pyrimidine, Stereochemistry, Adenosine A3 Receptor Antagonists, Adenosine receptor antagonists, Ligands, chemistry.chemical_compound, Structure-Activity Relationship, Carboxylate derivative, Drug Discovery, 4-d]pyrimidine, Pyrazolo[3, Molecule, Structure–activity relationship, Humans, Homology modeling, Carboxylate, Pharmacology, Structure-affinity relationship, Molecular Structure, Drug Discovery3003 Pharmaceutical Science, Organic Chemistry, Receptor, Adenosine A3, Antagonist, General Medicine, Adenosine receptor, Combinatorial chemistry, Carboxylate derivatives, Pyrimidines, chemistry, Molecular docking, Pyrazoles, Selectivity, Adenosine receptor antagonist

وصف الملف: STAMPA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a48082a7ebd8c072c24cb1b68c32eceb
https://pubmed.ncbi.nlm.nih.gov/25633494

المؤلفون: Sonja Kachler, Anton V. Dolzhenko, Evelyn Pei Rong Lee, Anna V. Dolzhenko, Silvia Paoletta, Stefano Moro, Giampiero Spalluto, Stephanie Federico, Giorgia Pastorin, Siew Lee Cheong, Karl-Norbert Klotz

المساهمون: Cheong, S. L., Dolzhenko, A. V., Paoletta, S., Lee, E. P. R., Kachler, S., Federico, Stephanie, Klotz, K. N., Spalluto, Giampiero, Moro, S., Pastorin, G.

مصطلحات موضوعية: Scaffold, Structure-affinity relationship, Molecular model, Pyrimidine, Stereochemistry, Organic Chemistry, Clinical Biochemistry, selectivity, Pharmaceutical Science, Ring (chemistry), Biochemistry, Adenosine receptor, Affinities, Selective modulation, chemistry.chemical_compound, chemistry, Drug Discovery, Molecular Medicine, affinity, Selectivity, Molecular Biology

وصف الملف: STAMPA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8fe227a1bfee5caa948af6fe070fc17
https://hdl.handle.net/11368/2403682

المؤلفون: Chun Wei Yap, Siew Lee Cheong, Giorgia Pastorin, Giampiero Spalluto, Stephanie Federico, Gopalakrishnan Venkatesan, Priyankar Paira, Yi-Ming Shao

المساهمون: Cheong, S. L., Federico, Stephanie, Venkatesan, G., Paira, P., Shao, Y. M., Spalluto, Giampiero, Yap, C. W., Pastorin, G.

مصطلحات موضوعية: Steric effects, Models, Molecular, Quantitative structure–activity relationship, CoMFA, Molecular model, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Adenosine A3 Receptor Antagonists, Quantitative Structure-Activity Relationship, QSAR, Biochemistry, chemistry.chemical_compound, Drug Discovery, Humans, Receptor, Molecular Biology, chemistry.chemical_classification, Molecular Structure, Chemistry, Aryl, Organic Chemistry, Triazoles, Ligand (biochemistry), Pyrimidines, Molecular Medicine, Pyrazoles, Pharmacophore, Tricyclic, Protein Binding

وصف الملف: STAMPA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f16d81084d6d48e93db0013f4f957c
https://hdl.handle.net/11368/2403683

المؤلفون: Stephanie Federico, Gopalakrishnan Venkatesan, Ramasamy Jothibasu, Priyankar Paira, Alexander Laurence Mandel, Giampiero Spalluto, Siew Lee Cheong, Giorgia Pastorin

المساهمون: Cheong, S. L., Venkatesan, G., Paira, P., Jothibasu, R., Mandel, A. L., Federico, Stephanie, Spalluto, Giampiero, Pastorin, G.

المصدر: International Journal of Medicinal Chemistry, Vol 2011 (2011)
International Journal of Medicinal Chemistry

مصطلحات موضوعية: antagonists, business.industry, Adenosine receptor, Pyrazole, GPCR, lcsh:RM1-950, Rational design, Review Article, Pharmacology, Biochemistry, Pyrimidinones, lcsh:Therapeutics. Pharmacology, Drug Discovery, Molecular Medicine, Medicine, business, RENAL DISORDERS

وصف الملف: ELETTRONICO

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17db4fe035ae1d3d3c813a92096169ed
https://doaj.org/article/115af61f96cf49f59c1083a8e1eeb919

المؤلفون: Kenneth A. Jacobson, Giampiero Spalluto, Karl-Norbert Klotz, Stephanie Federico, Stefano Moro, Zhan-Guo Gao, Barbara Cacciari, Silvia Paoletta, Giorgia Pastorin, J N Siegel, Siew Lee Cheong, Stefano Stragliotto

المساهمون: Federico, Stephanie, Paoletta, S., Cheong, S. L., Pastorin, G., Cacciari, B., Stragliotto, S., Klotz, K. N., Siegel, J., Gao, Z. G., Jacobson, K. A., Moro, S., Spalluto, Giampiero

مصطلحات موضوعية: Models, Molecular, Stereochemistry, Protein Conformation, high affinity, ligand recognition, adenosine, Static Electricity, CHO Cells, Crystallography, X-Ray, Article, Receptor subtype, Radioligand Assay, Structure-Activity Relationship, Cricetulus, Cricetinae, Drug Discovery, Aqueous solubility, medicine, Animals, Humans, Biological evaluation, Aqueous solution, Chemistry, Triazines, Water, Triazoles, Adenosine, Adenosine receptor, Adenosine A2 Receptor Antagonists, HEK293 Cells, Solubility, Molecular Medicine, Amine gas treating, Selectivity, Hydrophobic and Hydrophilic Interactions, medicine.drug, Protein Binding

وصف الملف: STAMPA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fb0389bf7b0df9937a28f9398343b5c
https://hdl.handle.net/11368/2403684

المؤلفون: Karl-Norbert Klotz, Sonja Kachler, Silvia Paoletta, Giampiero Spalluto, Stefano Moro, Anton V. Dolzhenko, Stephanie Federico, Barbara Cacciari, Anna V. Dolzhenko, Giorgia Pastorin, Siew Lee Cheong

المساهمون: Cheong, S. L., Dolzhenko, A., Kachler, S., Paoletta, S., Federico, Stephanie, Cacciari, B., Klotz, K. N., Moro, S., Spalluto, Giampiero, Pastorin, G.

المصدر: Journal of medicinal chemistry. 53(8)

مصطلحات موضوعية: Models, Molecular, Molecular model, Stereochemistry, medicine.drug_class, receptor, receptors, Adenosine A3 Receptor Antagonists, CHO Cells, Adenosine A1 Receptor Antagonists, adenosine, antagonists, chemistry.chemical_compound, Radioligand Assay, Structure-Activity Relationship, Cricetulus, Furan, Cricetinae, Drug Discovery, Acetamides, medicine, Animals, Humans, Receptor, Furans, Aryl, Triazoles, Receptor antagonist, Adenosine, Adenosine receptor, Adenosine A2 Receptor Antagonists, Pyrimidines, chemistry, Molecular Medicine, Pyrazoles, Selectivity, Heterocyclic Compounds, 3-Ring, medicine.drug, Adenylyl Cyclases

وصف الملف: STAMPA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a078bca2a7ae527756485c4cecd5d6
https://pubmed.ncbi.nlm.nih.gov/20307065