المؤلفون: Papillon, Julien P. N., Nakajima, Katsumasa, Adair, Christopher D., Hempel, Jonathan, Jouk, Andriana O., Karki, Rajeshri G., Mathieu, Simon, Möbitz, Henrik, Ntaganda, Rukundo, Smith, Troy, Visser, Michael, Hill, Susan E., Hurtado, Felipe Kellermann, Chenail, Gregg, Bhang, Hyo-Eun C., Bric, Anka, Xiang, Kay, Bushold, Geoffrey, Gilbert, Tamara, Vattay, Anthony, Dooley, Julie, Costa, Emily A., Park, Isabel, Li, Ailing, Farley, David, Lounkine, Eugen, Yue, Q. Kimberley, Xie, Xiaoling, Zhu, Xiaoping, Kulathila, Raviraj, King, Daniel, Hu, Tiancen, Vulic, Katarina, Cantwell, John, Luu, Catherine, Jagani, Zainab

المصدر: Journal of Medicinal Chemistry ; volume 61, issue 22, page 10155-10172 ; ISSN 0022-2623 1520-4804

الاتاحة: https://doi.org/10.1021/acs.jmedchem.8b01318
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.8b01318

المؤلفون: Xie, Xiaoling, Baird, Daniel, Bowen, Kimberly, Capka, Vladimir, Chen, Jinyun, Chenail, Gregg, Cho, YoungShin, Dooley, Julia, Farsidjani, Ali, Fortin, Pascal, Kohls, Darcy, Kulathila, Raviraj, Lin, Fallon, McKay, Daniel, Rodrigues, Lindsey, Sage, David, Touré, B. Barry, van der Plas, Simon, Wright, Kirk, Xu, Ming, Yin, Hong, Levell, Julian, Pagliarini, Raymond A.

المصدر: Structure ; volume 25, issue 3, page 506-513 ; ISSN 0969-2126

الاتاحة: http://dx.doi.org/10.1016/j.str.2016.12.017
https://api.elsevier.com/content/article/PII:S0969212616304257?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0969212616304257?httpAccept=text/plain

المؤلفون: Cho, Young Shin, Levell, Julian R., Liu, Gang, Caferro, Thomas, Sutton, James, Shafer, Cynthia M., Costales, Abran, Manning, James R., Zhao, Qian, Sendzik, Martin, Shultz, Michael, Chenail, Gregg, Dooley, Julia, Villalba, Brian, Farsidjani, Ali, Chen, Jinyun, Kulathila, Raviraj, Xie, Xiaoling, Dodd, Stephanie, Gould, Ty, Liang, Guiqing, Heimbach, Tycho, Slocum, Kelly, Firestone, Brant, Pu, Minying, Pagliarini, Raymond, Growney, Joseph D.

مصطلحات موضوعية: 60 APPLIED LIFE SCIENCES

وصف الملف: application/pdf

Relation: http://www.osti.gov/servlets/purl/1515280; https://www.osti.gov/biblio/1515280; https://doi.org/10.1021/acsmedchemlett.7b00342

الاتاحة: http://www.osti.gov/servlets/purl/1515280
https://www.osti.gov/biblio/1515280
https://doi.org/10.1021/acsmedchemlett.7b00342

المؤلفون: Levell, Julian R., Caferro, Thomas, Chenail, Gregg, Dix, Ina, Dooley, Julia, Firestone, Brant, Fortin, Pascal D., Giraldes, John, Gould, Ty, Growney, Joseph D., Jones, Michael D., Kulathila, Raviraj, Lin, Fallon, Liu, Gang, Mueller, Arne, van der Plas, Simon, Slocum, Kelly, Smith, Troy, Terranova, Remi, Touré, B. Barry, Tyagi, Viraj, Wagner, Trixie, Xie, Xiaoling, Xu, Ming, Yang, Fan S., Zhou, Liping X., Pagliarini, Raymond, Cho, Young Shin

مصطلحات موضوعية: 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRYSCIENCES, 60 APPLIED LIFE SCIENCES

وصف الملف: application/pdf

Relation: http://www.osti.gov/servlets/purl/1404997; https://www.osti.gov/biblio/1404997; https://doi.org/10.1021/acsmedchemlett.6b00334

الاتاحة: http://www.osti.gov/servlets/purl/1404997
https://www.osti.gov/biblio/1404997
https://doi.org/10.1021/acsmedchemlett.6b00334

المؤلفون: Papillon, Julien, Nakajima, Katsumasa, Hempel, Jonathan, Karki, Rajeshri, Moebitz, Henrik, Ntaganda, Rukundo, Smith, Troy, Visser, Michael, Hill, Sue, Kellermann Hurtado, Felipe, Chenail, Gregg, Bhang, Hyo-Eun, Xiang, Xiaoqin, Bushold, Geoffrey, Gilbert, Tamara, Vattay, Anthony, Dooley, Julie, Costa, Emily, Adair, Chris, Jouk, Andriana, Li, Jingzhou, Bric, Anka, Park, Isabel, Li, Ailing, Farley, David, Lounkine, Eugen, Yue, Qing, Xie, Xiaoling, Kulathila, Raviraj, King, Daniel, Hu, Tiancen, Vulic, Katarina, Cantwell, John, Luu, Catherine, Jagani, Zainab

Relation: Papillon, Julien, Nakajima, Katsumasa, Hempel, Jonathan, Karki, Rajeshri, Moebitz, Henrik, Ntaganda, Rukundo, Smith, Troy, Visser, Michael, Hill, Sue, Kellermann Hurtado, Felipe, Chenail, Gregg, Bhang, Hyo-Eun, Xiang, Xiaoqin, Bushold, Geoffrey, Gilbert, Tamara, Vattay, Anthony, Dooley, Julie, Costa, Emily, Adair, Chris, Jouk, Andriana, Li, Jingzhou, Bric, Anka, Park, Isabel, Li, Ailing, Farley, David, Lounkine, Eugen, Yue, Qing, Xie, Xiaoling, Kulathila, Raviraj, King, Daniel, Hu, Tiancen, Vulic, Katarina, Cantwell, John, Luu, Catherine and Jagani, Zainab (2018) Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers. Journal of Medicinal Chemistry, 61 (22). pp. 10155-10172. ISSN 15204804

الاتاحة: https://oak.novartis.com/37141/
https://pubs.acs.org/doi/abs/10.1021/acs.jmedchem.8b01318?mi=aayia761&af=R&AllFiel
https://doi.org/10.1021/acs.jmedchem.8b01318

المؤلفون: Zhao, Qian, Manning, James, Sutton, James, Costales, Abran, Sendzik, Martin, Shafer, Cynthia, Levell, Julian, Liu, Gang, Caferro, Thomas, Cho, Young, Palermo, Mark, Chenail, Gregg, Dooley, Julie, Villalba, Brian, Farsidjani, Alireza, Chen, Jinyun, Dodd, Stephanie, Gould, Ty, Liang, Guiqing, Slocum, Kelly, Pu, Minying, Firestone, Brant, Growney, Joseph, Heimbach, Tycho, Pagliarini, Raymond

Relation: Zhao, Qian, Manning, James, Sutton, James, Costales, Abran, Sendzik, Martin, Shafer, Cynthia, Levell, Julian, Liu, Gang, Caferro, Thomas, Cho, Young, Palermo, Mark, Chenail, Gregg, Dooley, Julie, Villalba, Brian, Farsidjani, Alireza, Chen, Jinyun, Dodd, Stephanie, Gould, Ty, Liang, Guiqing, Slocum, Kelly, Pu, Minying, Firestone, Brant, Growney, Joseph, Heimbach, Tycho and Pagliarini, Raymond (2018) Optimization of 3-Pyrimidin-4-yl-oxazolidin-2-ones as Orally Bioavailable and Brain Penetrant Mutant IDH1 Inhibitors. ACS Medicinal Chemistry Letters, 9. pp. 746-751. ISSN 19485875

الاتاحة: https://oak.novartis.com/36100/
https://pubs.acs.org/doi/pdf/10.1021/acsmedchemlett.8b00182
https://doi.org/10.1021/acsmedchemlett.8b00182

المؤلفون: Whitehead, Lewis, Deng, Gejing, Lee, Lac, Chenail, Gregg, Leeds, Jennifer, Luu, Catherine, Palestrant, Deborah, Sachdeva, Meena, Yu, Robert, Lamarche, Matthew

Relation: Whitehead, Lewis, Deng, Gejing, Lee, Lac, Chenail, Gregg, Leeds, Jennifer, Luu, Catherine, Palestrant, Deborah, Sachdeva, Meena, Yu, Robert and Lamarche, Matthew (2011) In vitro and in vivo activities of novel, semisynthetic thiopeptide inhibitors of bacterial elongation factor Tu. Antimicrobial Agents and Chemotherapy, 55 (11). pp. 5277-5283. ISSN 0066-4804

الاتاحة: https://oak.novartis.com/20520/
http://aac.asm.org/cgi/reprint/55/11/5277
https://doi.org/10.1128/AAC.00582-11

المؤلفون: Chenail, Gregg, Brown, Nathan E., Shea, Ashley, Feire, Adam L., Deng, Gejing

المصدر: Analytical Biochemistry ; volume 411, issue 1, page 58-63 ; ISSN 0003-2697

الاتاحة: http://dx.doi.org/10.1016/j.ab.2010.12.017
https://api.elsevier.com/content/article/PII:S0003269710007888?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0003269710007888?httpAccept=text/plain

المؤلفون: Krstenansky, John L., Wang, Jihong, Chenail, Gregg R., Tiffany, Matthew R., Kuesters, Geoffrey M., Natke, Barbara C., Nestor, John L., Jr.

المصدر: Pharmaceutical Science and Research

مصطلحات موضوعية: proteinase, proteinase inhibitor, proteinase substrate, ADAM-10, consensus substrate motif, Medicinal and Pharmaceutical Chemistry, Medicine and Health Sciences, Pharmaceutics and Drug Design, Pharmacy and Pharmaceutical Sciences

وصف الملف: application/pdf

Relation: https://mds.marshall.edu/sp_psr/1; https://mds.marshall.edu/context/sp_psr/article/1000/viewcontent/krstenansky.probing.pdf

الاتاحة: https://mds.marshall.edu/sp_psr/1
https://mds.marshall.edu/context/sp_psr/article/1000/viewcontent/krstenansky.probing.pdf

المؤلفون: Krstenansky, John, Wang, Jihong, Chenail, Gregg, Tiffany, Matthew, Kuesters, Geoffrey, Natke, Barbara, Nestor, Jr., John

المصدر: Letters in Drug Design & Discovery ; volume 1, issue 1, page 6-13 ; ISSN 1570-1808

الاتاحة: http://dx.doi.org/10.2174/1570180043485770
http://eurekaselect.com/article/download/80803