المؤلفون: Faouzi Djebbari (6004379), Alexandros Rampotas (11933847), Fotios Panitsas (11933850), Wen Yuen Lim (11933853), Charlotte Lees (5864870), Ismini Tsagkaraki (11933856), Ana Rita Gomes (9089092), Steve Prideaux (11933859), Lucia Chen (7349012), Catherine Prodger (11933862), Akhil Khera (11933865), Nicola Gray (1590448), Lauren Ellis (11933868), Gina Sangha (11933871), Toby A. Eyre (8479401), Sally Moore (6078818), Jaimal Kothari (6078821), Karthik Ramasamy (795392)

مصطلحات موضوعية: Medicine, Physiology, Pharmacology, Biotechnology, Developmental Biology, Cancer, Mental Health, Hematology, Infectious Diseases, overall response rate, focus towards reducing, enable meaningful comparisons, 89 &# 8211, clinical trial setting, clinical outcomes included, patients treated exclusively, proven prognostic values, higher incidence rate, based vcd therapy, revised myeloma co, worse ae outcomes, individualise treatment decisions, 61 &# 8211, myeloma risk profile, shorter median os, clinical outcomes according, frail patients compared, treating frail patients, os ), progression

Relation: https://figshare.com/articles/figure/Inclusion_exclusion_in_the_cohort_and_frailty_score_categories_/18175683

الاتاحة: https://doi.org/10.1371/journal.pone.0262388.g001

المؤلفون: Faouzi Djebbari (6004379), Alexandros Rampotas (11933847), Fotios Panitsas (11933850), Wen Yuen Lim (11933853), Charlotte Lees (5864870), Ismini Tsagkaraki (11933856), Ana Rita Gomes (9089092), Steve Prideaux (11933859), Lucia Chen (7349012), Catherine Prodger (11933862), Akhil Khera (11933865), Nicola Gray (1590448), Lauren Ellis (11933868), Gina Sangha (11933871), Toby A. Eyre (8479401), Sally Moore (6078818), Jaimal Kothari (6078821), Karthik Ramasamy (795392)

مصطلحات موضوعية: Medicine, Physiology, Pharmacology, Biotechnology, Developmental Biology, Cancer, Mental Health, Hematology, Infectious Diseases, overall response rate, focus towards reducing, enable meaningful comparisons, 89 &# 8211, clinical trial setting, clinical outcomes included, patients treated exclusively, proven prognostic values, higher incidence rate, based vcd therapy, revised myeloma co, worse ae outcomes, individualise treatment decisions, 61 &# 8211, myeloma risk profile, shorter median os, clinical outcomes according, frail patients compared, treating frail patients, os ), progression

Relation: https://figshare.com/articles/figure/Overall_survival_OS_by_frailty_frail_vs_intermediate_or_fit_46_months_vs_not_reached_HR_1_94_95_CI_0_89_4_2_p_0_094_/18175686

الاتاحة: https://doi.org/10.1371/journal.pone.0262388.g002

المؤلفون: Faouzi Djebbari (6004379), Alexandros Rampotas (11933847), Fotios Panitsas (11933850), Wen Yuen Lim (11933853), Charlotte Lees (5864870), Ismini Tsagkaraki (11933856), Ana Rita Gomes (9089092), Steve Prideaux (11933859), Lucia Chen (7349012), Catherine Prodger (11933862), Akhil Khera (11933865), Nicola Gray (1590448), Lauren Ellis (11933868), Gina Sangha (11933871), Toby A. Eyre (8479401), Sally Moore (6078818), Jaimal Kothari (6078821), Karthik Ramasamy (795392)

مصطلحات موضوعية: Medicine, Physiology, Pharmacology, Biotechnology, Developmental Biology, Cancer, Mental Health, Hematology, Infectious Diseases, overall response rate, focus towards reducing, enable meaningful comparisons, 89 &# 8211, clinical trial setting, clinical outcomes included, patients treated exclusively, proven prognostic values, higher incidence rate, based vcd therapy, revised myeloma co, worse ae outcomes, individualise treatment decisions, 61 &# 8211, myeloma risk profile, shorter median os, clinical outcomes according, frail patients compared, treating frail patients, os ), progression

Relation: https://figshare.com/articles/figure/Progression-free_survival_PFS_by_frailty_frail_vs_intermediate_or_fit_11_8_vs_9_9_months_HR_0_99_95_CI_0_61_1_61_P_0_982_/18175692

الاتاحة: https://doi.org/10.1371/journal.pone.0262388.g003

المؤلفون: Faouzi Djebbari (6004379), Alexandros Rampotas (11933847), Fotios Panitsas (11933850), Wen Yuen Lim (11933853), Charlotte Lees (5864870), Ismini Tsagkaraki (11933856), Ana Rita Gomes (9089092), Steve Prideaux (11933859), Lucia Chen (7349012), Catherine Prodger (11933862), Akhil Khera (11933865), Nicola Gray (1590448), Lauren Ellis (11933868), Gina Sangha (11933871), Toby A. Eyre (8479401), Sally Moore (6078818), Jaimal Kothari (6078821), Karthik Ramasamy (795392)

مصطلحات موضوعية: Medicine, Physiology, Pharmacology, Biotechnology, Developmental Biology, Cancer, Mental Health, Hematology, Infectious Diseases, overall response rate, focus towards reducing, enable meaningful comparisons, 89 &# 8211, clinical trial setting, clinical outcomes included, patients treated exclusively, proven prognostic values, higher incidence rate, based vcd therapy, revised myeloma co, worse ae outcomes, individualise treatment decisions, 61 &# 8211, myeloma risk profile, shorter median os, clinical outcomes according, frail patients compared, treating frail patients, os ), progression

Relation: https://figshare.com/articles/dataset/Baseline_patient_disease_and_treatment_characteristics_for_the_total_cohort_and_for_the_different_MRP_subgroups_frail_vs_intermediate_or_fit_/18175695

الاتاحة: https://doi.org/10.1371/journal.pone.0262388.t001

المؤلفون: Faouzi Djebbari (6004379), Alexandros Rampotas (11933847), Fotios Panitsas (11933850), Wen Yuen Lim (11933853), Charlotte Lees (5864870), Ismini Tsagkaraki (11933856), Ana Rita Gomes (9089092), Steve Prideaux (11933859), Lucia Chen (7349012), Catherine Prodger (11933862), Akhil Khera (11933865), Nicola Gray (1590448), Lauren Ellis (11933868), Gina Sangha (11933871), Toby A. Eyre (8479401), Sally Moore (6078818), Jaimal Kothari (6078821), Karthik Ramasamy (795392)

مصطلحات موضوعية: Medicine, Physiology, Pharmacology, Biotechnology, Developmental Biology, Cancer, Mental Health, Hematology, Infectious Diseases, overall response rate, focus towards reducing, enable meaningful comparisons, 89 &# 8211, clinical trial setting, clinical outcomes included, patients treated exclusively, proven prognostic values, higher incidence rate, based vcd therapy, revised myeloma co, worse ae outcomes, individualise treatment decisions, 61 &# 8211, myeloma risk profile, shorter median os, clinical outcomes according, frail patients compared, treating frail patients, os ), progression

Relation: https://figshare.com/articles/dataset/Reasons_for_discontinuation_of_first_line_VCD_myeloma_therapy_in_the_total_cohort_in_MRP_subgroups_frail_vs_intermediate_or_fit_and_in_co-morbidity_subgroups_/18175701

الاتاحة: https://doi.org/10.1371/journal.pone.0262388.t002

المؤلفون: Faouzi Djebbari (6004379), Alexandros Rampotas (11933847), Fotios Panitsas (11933850), Wen Yuen Lim (11933853), Charlotte Lees (5864870), Ismini Tsagkaraki (11933856), Ana Rita Gomes (9089092), Steve Prideaux (11933859), Lucia Chen (7349012), Catherine Prodger (11933862), Akhil Khera (11933865), Nicola Gray (1590448), Lauren Ellis (11933868), Gina Sangha (11933871), Toby A. Eyre (8479401), Sally Moore (6078818), Jaimal Kothari (6078821), Karthik Ramasamy (795392)

مصطلحات موضوعية: Medicine, Physiology, Pharmacology, Biotechnology, Developmental Biology, Cancer, Mental Health, Hematology, Infectious Diseases, overall response rate, focus towards reducing, enable meaningful comparisons, 89 &# 8211, clinical trial setting, clinical outcomes included, patients treated exclusively, proven prognostic values, higher incidence rate, based vcd therapy, revised myeloma co, worse ae outcomes, individualise treatment decisions, 61 &# 8211, myeloma risk profile, shorter median os, clinical outcomes according, frail patients compared, treating frail patients, os ), progression

Relation: https://figshare.com/articles/dataset/Response_rates_to_first_line_VCD_myeloma_therapy_in_the_total_cohort_in_MRP_subgroups_frail_vs_intermediate_or_fit_and_in_co-morbidity_subgroups_/18175704

الاتاحة: https://doi.org/10.1371/journal.pone.0262388.t003

المؤلفون: Faouzi Djebbari (6004379), Alexandros Rampotas (11933847), Fotios Panitsas (11933850), Wen Yuen Lim (11933853), Charlotte Lees (5864870), Ismini Tsagkaraki (11933856), Ana Rita Gomes (9089092), Steve Prideaux (11933859), Lucia Chen (7349012), Catherine Prodger (11933862), Akhil Khera (11933865), Nicola Gray (1590448), Lauren Ellis (11933868), Gina Sangha (11933871), Toby A. Eyre (8479401), Sally Moore (6078818), Jaimal Kothari (6078821), Karthik Ramasamy (795392)

مصطلحات موضوعية: Medicine, Physiology, Pharmacology, Biotechnology, Developmental Biology, Cancer, Mental Health, Hematology, Infectious Diseases, overall response rate, focus towards reducing, enable meaningful comparisons, 89 &# 8211, clinical trial setting, clinical outcomes included, patients treated exclusively, proven prognostic values, higher incidence rate, based vcd therapy, revised myeloma co, worse ae outcomes, individualise treatment decisions, 61 &# 8211, myeloma risk profile, shorter median os, clinical outcomes according, frail patients compared, treating frail patients, os ), progression

Relation: https://figshare.com/articles/dataset/Univariate_UVA_and_multivariate_MVA_analyses_for_PFS_and_OS_/18175707

الاتاحة: https://doi.org/10.1371/journal.pone.0262388.t004

المؤلفون: Faouzi Djebbari (6004379), Alexandros Rampotas (11933847), Fotios Panitsas (11933850), Wen Yuen Lim (11933853), Charlotte Lees (5864870), Ismini Tsagkaraki (11933856), Ana Rita Gomes (9089092), Steve Prideaux (11933859), Lucia Chen (7349012), Catherine Prodger (11933862), Akhil Khera (11933865), Nicola Gray (1590448), Lauren Ellis (11933868), Gina Sangha (11933871), Toby A. Eyre (8479401), Sally Moore (6078818), Jaimal Kothari (6078821), Karthik Ramasamy (795392)

مصطلحات موضوعية: Medicine, Physiology, Pharmacology, Biotechnology, Developmental Biology, Cancer, Mental Health, Hematology, Infectious Diseases, overall response rate, focus towards reducing, enable meaningful comparisons, 89 &# 8211, clinical trial setting, clinical outcomes included, patients treated exclusively, proven prognostic values, higher incidence rate, based vcd therapy, revised myeloma co, worse ae outcomes, individualise treatment decisions, 61 &# 8211, myeloma risk profile, shorter median os, clinical outcomes according, frail patients compared, treating frail patients, os ), progression

Relation: https://figshare.com/articles/dataset/Toxicities_associated_with_VCD_therapy_in_the_total_cohort_/18175710

الاتاحة: https://doi.org/10.1371/journal.pone.0262388.t005