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1Academic Journal
المؤلفون: Stine Gunnersen, Jeong Tangkjær Shim, Fan Liu, Uwe J.F. Tietge, Charlotte Brandt Sørensen, Jacob Fog Bentzon
المصدر: Atherosclerosis Plus, Vol 55, Iss , Pp 12-20 (2024)
مصطلحات موضوعية: Smooth muscle cells, CCL2, Inducible knockout, Inflammation, Atherosclerosis, Diseases of the circulatory (Cardiovascular) system, RC666-701
وصف الملف: electronic resource
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2Academic Journal
المؤلفون: Stine Andersen, Julie Birkmose Axelsen, Steffen Ringgaard, Jens Randel Nyengaard, Signe Holm Nielsen, Federica Genovese, Morten Asser Karsdal, Janus Adler Hyldebrandt, Charlotte Brandt Sørensen, Frances S. de Man, Harm Jan Bogaard, Jens Erik Nielsen-Kudsk, Asger Andersen
المصدر: Pulmonary Circulation, Vol 9 (2019)
مصطلحات موضوعية: Diseases of the circulatory (Cardiovascular) system, RC666-701, Diseases of the respiratory system, RC705-779
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2045-8940
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3Academic Journal
المؤلفون: Yonglun Luo, Lin Lin, Lars Bolund, Charlotte Brandt Sørensen
المصدر: BioTechniques, Vol 56, Iss 5, Pp 263-268 (2014)
مصطلحات موضوعية: gene targeting, rAAV, Golden Gate cloning, p53, tau, Biology (General), QH301-705.5
وصف الملف: electronic resource
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4Academic Journal
المؤلفون: Christian Bo Poulsen, Martin Bødtker Mortensen, Wolfgang Koechling, Charlotte Brandt Sørensen, Jacob Fog Bentzon
المصدر: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 2 (2016)
مصطلحات موضوعية: androgen deprivation therapy, atherosclerosis, inflammation, testosterone, Diseases of the circulatory (Cardiovascular) system, RC666-701
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2047-9980
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5Academic Journal
المؤلفون: Thomas Koed Doktor, Lisbeth Dahl Schrøder, Henriette Skovgaard Andersen, Sabrina Brøner, Anna Kitewska, Charlotte Brandt Sørensen, Brage Storstein Andresen
المصدر: PLoS ONE, Vol 9, Iss 6, p e98841 (2014)
وصف الملف: electronic resource
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6Academic Journal
المؤلفون: Fei Gao, Yonglun Luo, Shengting Li, Jian Li, Lin Lin, Anders Lade Nielsen, Charlotte Brandt Sørensen, Gábor Vajta, Jun Wang, Xiuqing Zhang, Yutao Du, Huanming Yang, Lars Bolund
المصدر: PLoS ONE, Vol 6, Iss 10, p e25901 (2011)
وصف الملف: electronic resource
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7
المؤلفون: Charlotte Brandt Sørensen, Hans Erik Bøtker, Jacob Johnsen, Jan Hansen, Jan Møller Nielsen, Nichlas Riise Jespersen, Casper Carlsen Elkjær
المصدر: Drug Design, Development and Therapy. 14:2549-2560
مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Cardioprotection, MAPK/ERK pathway, biology, Kinase, Ischemia, Pharmaceutical Science, medicine.disease, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, chemistry, 030220 oncology & carcinogenesis, Drug Discovery, medicine, biology.protein, Propidium iodide, STAT3, Reperfusion injury, Protein kinase B
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8
المؤلفون: David Filgueiras-Rama, Charlotte Brandt Sørensen, Gonzalo J. López-Martín, Alvaro Macias, Javier Sánchez-González, Raúl Sánchez-Sánchez, Borja Ibanez, Vicente Andrés, María J. Andrés-Manzano, Cristina González-Gómez, Manuel Lobo, Ana Barettino, Henrik Callesen, Carlos Galán-Arriola, Gro Grunnet Pløen, Antonio de Molina, Jose Manuel Alfonso, Beatriz Dorado, Joaquín Gadea, Pilar Gonzalo, Ying Liu
المساهمون: Fundación ProCNIC, Progeria Research Foundation, Ministerio de Ciencia, Innovación y Universidades (España), Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF), University of Murcia (España), Gobierno de la Región de Murcia (España)
المصدر: Dorado, B, Pløen, G G, Barettino, A, Macías, A, Gonzalo, P, Andrés-Manzano, M J, González-Gómez, C, Galán-Arriola, C, Alfonso, J M, Lobo, M, López-Martín, G J, Molina, A, Sánchez-Sánchez, R, Gadea, J, Sánchez-González, J, Liu, Y, Callesen, H, Filgueiras-Rama, D, Ibáñez, B, Sørensen, C B & Andrés, V 2019, ' Generation and characterization of a novel knockin minipig model of Hutchinson-Gilford progeria syndrome ', Cell Discovery, vol. 5, 16 . https://doi.org/10.1038/s41421-019-0084-z
Dorado, B, Pløen, G G, Barettino, A, Macias, A, Gonzalo, P, Andrés-Manzano, M J, González-Gómez, C, Galán-Arriola, C, Alfonso, J M, Lobo, M, López-Martin, G J, Molina, A, Sánchez, R, Gadea, J, Sánchez-González, J, Liu, Y, Callesen, H, Filgueiras-Rama, D, Ibánez, B, Sørensen, C B & Andrés, V 2019, ' Generation and characterization of a novel knockin minipig model of Hutchinson-Gilford progeria syndrome ', Cell Discovery, vol. 5, pp. 16 . https://doi.org/10.1038/s41421-019-0084-z
Repisalud
Instituto de Salud Carlos III (ISCIII)
Cell Discovery
Cell Discovery, Vol 5, Iss 1, Pp 1-15 (2019)مصطلحات موضوعية: Premature aging, congenital, hereditary, and neonatal diseases and abnormalities, Disease, Bioinformatics, Biochemistry, Article, LMNA, 03 medical and health sciences, 0302 clinical medicine, Genetics, medicine, lcsh:QH573-671, Molecular Biology, 030304 developmental biology, 0303 health sciences, Progeria, integumentary system, lcsh:Cytology, business.industry, Genetic disorder, nutritional and metabolic diseases, Cell Biology, medicine.disease, Progerin, Lipodystrophy, business, 030217 neurology & neurosurgery, Lamin
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aef0e35b69554c1c20e731f5ab90ee5a
https://pure.au.dk/portal/da/publications/generation-and-characterization-of-a-novel-knockin-minipig-model-of-hutchinsongilford-progeria-syndrome(821e5974-88c8-459e-906f-1cf2c3b31462).html -
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المؤلفون: Torben Larsen, Charlotte Brandt Sørensen, Mette K. Hagensen, Rong Li, Henrik Callesen, Jian Li, Lars Bolund, Ying Liu, Jeong Shim, Jacob F. Bentzon, Peter M. H. Heegaard, Christina Christoffersen, Christian Bo Poulsen, Mette Schmidt
المصدر: Transgenic research. 27(5)
مصطلحات موضوعية: 0301 basic medicine, 03 medical and health sciences, medicine.medical_specialty, 030104 developmental biology, Endocrinology, Internal medicine, Genetics, medicine, Animal Science and Zoology, Biology, Agronomy and Crop Science, Biotechnology, Apolipoprotein E deficiency
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10
المصدر: The Journal of Pathology. 238:257-266
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Pathology, business.industry, Translational research, 030204 cardiovascular system & hematology, Coronary heart disease, Pathology and Forensic Medicine, 03 medical and health sciences, Important research, 030104 developmental biology, 0302 clinical medicine, Small animal, Ischaemic stroke, Risk stratification, Cardiovascular agent, medicine, Intensive care medicine, business, Large animal
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11
المؤلفون: Christian Bo Poulsen, Charlotte Brandt Sørensen, Juan Li, Christina Christoffersen, Mette Schmidt, Ying Liu, Lars Bolund, Rong Li, Henrik Callesen, Jacob F. Bentzon, Peter M. H. Heegaard, Jeong Shim, Torben Larsen, Mette K. Hagensen
المصدر: JACC: Basic to Translational Science
Shim, J, Poulsen, C B, Hagensen, M K, Larsen, T, Heegaard, P M H, Christoffersen, C, Bolund, L, Schmidt, M, Liu, Y, Li, J, Li, R, Callesen, H, Bentzon, J F & Sørensen, C B 2017, ' Apolipoprotein E deficiency increases remnant lipoproteins and accelerates progressive atherosclerosis, but not xanthoma formation, in gene modified minipigs ', J A C C: Basic to Translational Science, vol. 2, no. 5, pp. 591-600 . https://doi.org/10.1016/j.jacbts.2017.06.004
Shim, J, Poulsen, C B, Hagensen, M K, Larsen, T, Heegaard, P M H, Christoffersen, C, Bolund, L, Schmidt, M, Liu, Y, Li, J, Li, R, Callesen, H, Bentzon, J F & Sørensen, C B 2017, ' Apolipoprotein E Deficiency Increases Remnant Lipoproteins and Accelerates Progressive Atherosclerosis, But Not Xanthoma Formation, in Gene-Modified Minipigs ', JACC: Basic to translational science, vol. 2, no. 5, pp. 591-600 . https://doi.org/10.1016/j.jacbts.2017.06.004
Shim, J, Poulsen, C B, Hagensen, M K, Larsen, T, Heegaard, P M H, Christoffersen, C, Bolund, L, Schmidt, M, Liu, Y, Li, J, Li, R, Callesen, H, Bentzon, J F & Sørensen, C B 2017, ' Apolipoprotein E Deficiency Increases Remnant Lipoproteins and Accelerates Progressive Atherosclerosis, But Not Xanthoma Formation, in Gene-Modified Minipigs ', JACC: Basic to Translational Science, vol. 2, no. 5, pp. 591-600 . https://doi.org/10.1016/j.jacbts.2017.06.004
JACC: Basic to Translational Science, Vol 2, Iss 5, Pp 591-600 (2017)مصطلحات موضوعية: 0301 basic medicine, Apolipoprotein E, pig, lcsh:Diseases of the circulatory (Cardiovascular) system, medicine.medical_specialty, Somatic cell, SMC, smooth muscle cell, 030204 cardiovascular system & hematology, Xanthoma, Virus, law.invention, Remnant cholesterol dysbetalipoproteinemia, LF, low-fat, 03 medical and health sciences, PRECLINICAL RESEARCH, cDNA, complementary DNA, 0302 clinical medicine, IDL, intermediate-density lipoprotein, law, Internal medicine, remnant cholesterol dysbetalipoproteinemia, LDL, low-density lipoprotein, medicine, Neo, neomycin, Gene, apolipoprotein E, Pig, HFHC, high-fat high-cholesterol, LAD, left anterior descending (coronary artery), Chemistry, Gene targeting, VLDL, very-low-density lipoprotein, medicine.disease, Atherosclerosis, rAAV, recombinant adeno-associated virus, APOB, apolipoprotein B, 030104 developmental biology, Endocrinology, lcsh:RC666-701, LDLR, low-density lipoprotein receptor, Recombinant DNA, lipids (amino acids, peptides, and proteins), APOE, apolipoprotein E, atherosclerosis, Cardiology and Cardiovascular Medicine, Chylomicron
وصف الملف: application/pdf
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12
المؤلفون: Jacob F. Bentzon, Charlotte Brandt Sørensen, Jan O. Secher, Yonglun Luo, Henrik Callesen, Ying Liu, Mette Schmidt, Stoyan G. Petkov, Dong Li, Kristine K. Freude, Vanessa Jane Hall, Poul Hyttel
المصدر: Secher, J, Liu, Y, Petkov, S, Luo, Y, Li, D, Hall, V J, Schmidt, M, Callesen, H, Bentzon, J F, Sørensen, C B, Freude, K K & Hyttel, P 2017, ' Evaluation of porcine stem cells competence for somatic cell nuclear transfer and production of cloned animals ', Animal Reproduction Science, vol. 178, pp. 40-49 . https://doi.org/10.1016/j.anireprosci.2017.01.007
مصطلحات موضوعية: 0301 basic medicine, Male, Pluripotent Stem Cells, Nuclear Transfer Techniques, Swine, Cloning, Organism, Green Fluorescent Proteins, Embryonic Development, Embryoid body, Biology, Cell Line, Animals, Genetically Modified, 03 medical and health sciences, Endocrinology, Food Animals, Pregnancy, Animals, Induced pluripotent stem cell, Induced stem cells, 030102 biochemistry & molecular biology, General Medicine, Fibroblasts, Cellular Reprogramming, Embryo Transfer, Embryo, Mammalian, Embryonic stem cell, Molecular biology, Cell biology, 030104 developmental biology, Multipotent Stem Cell, Somatic cell nuclear transfer, Animal Science and Zoology, Female, Stem cell, Adult stem cell
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82655d11d2b48f2a62ea005614effbd0
https://pure.au.dk/portal/da/publications/evaluation-of-porcine-stem-cells-competence-for-somatic-cell-nuclear-transfer-and-production-of-cloned-animals(80f11a98-9a07-4920-91b2-1e242f33f6f5).html -
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المصدر: Luo, Y, Kofod-Olsen, E, Christensen, R, Sørensen, C B & Bolund, L 2012, ' Targeted Genome Editing by Recombinant Adeno-Associated Virus (rAAV) Vectors for Generating Genetically Modified Pigs ', Journal of Genetics and Genomics, vol. 39, no. 6, pp. 269-74 . https://doi.org/10.1016/j.jgg.2012.05.004
مصطلحات موضوعية: Nuclear Transfer Techniques, Swine, viruses, Genetic enhancement, Genetic Vectors, Gene Transfer Techniques, Gene targeting, Dependovirus, Biology, medicine.disease_cause, Virology, Genetically modified organism, Animals, Genetically Modified, Genome editing, Gene Targeting, Genetics, medicine, Animals, Humans, Somatic cell nuclear transfer, Vector (molecular biology), Homologous recombination, Molecular Biology, Adeno-associated virus
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14
المؤلفون: Thomas G. Jensen, Charlotte Brandt Sørensen, Yonglun Luo, Lin Lin, Lars Bolund
المصدر: Luo, Y, Lin, L, Bolund, L, Jensen, T G & Sørensen, C B 2012, ' Genetically modified pigs for biomedical research ', Journal of Inherited Metabolic Disease, vol. 35, no. 4, pp. 695-713 . https://doi.org/10.1007/s10545-012-9475-0
مصطلحات موضوعية: Cloning, Biomedical Research, Swine, Xenotransplantation, medicine.medical_treatment, Gene transfer, Computational biology, Biology, Human genetics, Genetically modified organism, Animals, Genetically Modified, Immunology, Genetics, medicine, Animals, Humans, Somatic cell nuclear transfer, Engineering tool, Genetics (clinical), Large animal
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15
المؤلفون: Charlotte Brandt Sørensen, Yonglun Luo, Lars Bolund
المصدر: Luo, Y, Bolund, L & Sørensen, C B 2012, ' Pig gene knockout by rAAV-mediated homologous recombination: comparison of BRCA1 gene knockout efficiency in Yucatan and Göttingen fibroblasts with slightly different target sequences ', Transgenic Research, vol. 21, pp. 671-676 . https://doi.org/10.1007/s11248-011-9563-1
مصطلحات موضوعية: Nuclear Transfer Techniques, Swine, Genetic Vectors, Genes, BRCA1, Biology, Genome, Homology (biology), Gene Knockout Techniques, Exon, Genetics, Animals, Cloning, Molecular, Homologous Recombination, Gene, Gene knockout, Gene targeting, Exons, Dependovirus, Fibroblasts, Molecular biology, genomic DNA, Models, Animal, Swine, Miniature, Animal Science and Zoology, Homologous recombination, Agronomy and Crop Science, Biotechnology
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16
المؤلفون: M. Molnár, Peter M. Kragh, Charlotte Brandt Sørensen, Masaabc Kuwayama, Gábor Vajta, Xiuqing Zhang, Csaba Pribenszky, Yutao Du, Mette Schmidt, Huanming Yang, Stig Purup, Juan Li, I.B. Bøgh, Lin Lin, Lars Bolund
المصدر: Du, Y, Lin, L, Schmidt, M, Bøgh, I B, Kragh, P M, Sørensen, C B, Li, J, Purup, S, Pribenszky, C, Molnár, M, Kuwayama, M, Zhang, X, Yang, H, Bolund, L & Vajta, G 2008, ' High Hydrostatic Pressure Treatment of Porcine Oocytes before Handmade Cloning Improves Developmental Competence and Cryosurvival ', Cloning and Stem Cells, vol. 10, no. 3, pp. 325-330 . https://doi.org/10.1089/clo.2007.0089
مصطلحات موضوعية: Nuclear Transfer Techniques, Cell Survival, Cloning, Organism, Sus scrofa, Hydrostatic pressure, Biology, Embryo Culture Techniques, Andrology, Random Allocation, Pregnancy, In vivo, Hydrostatic Pressure, medicine, Animals, Humans, Blastocyst, Cryopreservation, Estrous cycle, Fetus, Embryo, Anatomy, medicine.disease, medicine.anatomical_structure, Oocytes, Gestation, Female, Developmental Biology, Biotechnology
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17
المؤلفون: Peter Brøgger, Lars Aagaard, H. D. Pedersen, Peter Bross, Sif Groth Rønn, Tino Klein, Charlotte Brandt Sørensen, Trine Skov Petersen, Rasha Abdelkadhem Al-Saaidi, Yan Zhou, Dianna Hussmann, Yonglun Luo, Yong Liu, Anders Lade Nielsen, Guangqian Zhou, Lin Lin, Shuang Tan, Lars Bolund
المصدر: Zhou, Y, Liu, Y, Hussmann, D, Brøgger, P, Al-Saaidi, R A, Tan, S, Lin, L, Petersen, T S, Zhou, G Q, Bross, P, Aagaard, L, Klein, T, Rønn, S G, Pedersen, H D, Bolund, L, Nielsen, A L, Sørensen, C B & Luo, Y 2016, ' Enhanced genome editing in mammalian cells with a modified dual-fluorescent surrogate system ', Cellular and Molecular Life Sciences, vol. 73, no. 13, pp. 2543-63 . https://doi.org/10.1007/s00018-015-2128-3
مصطلحات موضوعية: 0301 basic medicine, Chromosomal Proteins, Non-Histone, Swine, Golden Gate Cloning, Genetic Vectors, Computational biology, Biology, Fluorescence, Genome engineering, Receptor, IGF Type 1, 03 medical and health sciences, Cellular and Molecular Neuroscience, Gene Knockout Techniques, Genome editing, Genes, Reporter, Transcription Activator-Like Effector Nucleases, CRISPR, Animals, Humans, Clustered Regularly Interspaced Short Palindromic Repeats, Homologous Recombination, Molecular Biology, Gene, Cells, Cultured, Pharmacology, Genetics, Gene Editing, Transcription activator-like effector nuclease, Cas9, Gene targeting, Receptors, Somatomedin, Cell Biology, Fibroblasts, 030104 developmental biology, HEK293 Cells, Chromobox Protein Homolog 5, MCF-7 Cells, Molecular Medicine, CRISPR-Cas Systems
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18
المؤلفون: Christian Bo Poulsen, Martin Bødtker Mortensen, Wolfgang Koechling, Charlotte Brandt Sørensen, Jacob Fog Bentzon
المصدر: Circulation. 132
مصطلحات موضوعية: Physiology (medical), Cardiology and Cardiovascular Medicine
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19
المؤلفون: Jacob Fog Bentzon, Charlotte Brandt Sørensen, Peter Kragh, Jacob Giehm Mikkelsen, Erling Falk, Lars Bolund, Thomas Juhl Corydon
المصدر: Bentzon, J F, Sørensen, C B, Kragh, P, Mikkelsen, J G, Falk, E, Bolund, L & Corydon, T J jun.. 26 2015, Pig model for atherosclerosis. Europe Patent EP2134847, June 24, 2015 .
Aarhus UniversityURL الوصول: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::cdb75b09f8f6b7a31c8838133c2c70c2
https://pure.au.dk/portal/da/publications/pig-model-for-atherosclerosis-europe-patent-ep2134847-june-24-2015(4031b111-cc7f-4685-9f5a-7a54603eaba4).html -
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المؤلفون: Charlotte Brandt Sørensen, Thomas G. Jensen, Peter K.A. Jensen, Uffe Birk Jensen, Lars Bolund, Niels Gregersen, Brage S. Andresen
المصدر: Experimental Dermatology. 12:472-479
مصطلحات موضوعية: chemistry.chemical_classification, Keratin 14, Keratin Filament, integumentary system, macromolecular substances, Dermatology, Biology, medicine.disease, Biochemistry, Molecular biology, Keratin 5, Epidermolysis bullosa simplex, HaCaT, chemistry, Mutant protein, Keratin, medicine, Epidermolysis bullosa, Molecular Biology