المؤلفون: W. Cameron Black, Abbas Abdoli, Xiuli An, Anick Auger, Patrick Beaulieu, Michel Bernatchez, Cathy Caron, Amandine Chefson, Sheldon Crane, Mohamed Diallo, Stéphane Dorich, Lee D. Fader, Gino B. Ferraro, Sara Fournier, Qi Gao, Yelena Ginzburg, Martine Hamel, Yongshuai Han, Paul Jones, Stéphanie Lanoix, Cyrus M. Lacbay, Marie-Eve Leclaire, Maayan Levy, Yael Mamane, Amina Mulani, Robert Papp, Charles Pellerin, Audrey Picard, Alexander Skeldon, Kathryn Skorey, Rino Stocco, Miguel St.-Onge, Jean-François Truchon, Vouy Linh Truong, Michal Zimmermann, Michael Zinda, Anne Roulston

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Genetics, Molecular Biology, Pharmacology, Biotechnology, Immunology, Cancer, Science Policy, Virology, Computational Biology, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, preclinical evaluation focused, intermittent dosing schedules, excellent adme properties, related kinase mtor, key hydrogen bond, key kinase, synthetic lethal, single agent, pharmacophore model, nct04855656 ), mitigate anemia, erythroid compartment, damage response, attractive target, allow recovery

Relation: https://figshare.com/articles/journal_contribution/Discovery_of_the_Potent_and_Selective_ATR_Inhibitor_Camonsertib_RP-3500_/25126367

الاتاحة: https://doi.org/10.1021/acs.jmedchem.3c01917.s001
https://figshare.com/articles/journal_contribution/Discovery_of_the_Potent_and_Selective_ATR_Inhibitor_Camonsertib_RP-3500_/25126367

المؤلفون: Monica Bubenik, Pavel Mader, Philippe Mochirian, Fréderic Vallée, Jillian Clark, Jean-François Truchon, Alexander L. Perryman, Victor Pau, Igor Kurinov, Karl E. Zahn, Marie-Eve Leclaire, Robert Papp, Marie-Claude Mathieu, Martine Hamel, Nicole M. Duffy, Claude Godbout, Matias Casas-Selves, Jean-Pierre Falgueyret, Prasamit S. Baruah, Olivier Nicolas, Rino Stocco, Hugo Poirier, Giovanni Martino, Alexanne Bonneau Fortin, Anne Roulston, Amandine Chefson, Stéphane Dorich, Miguel St-Onge, Purvish Patel, Charles Pellerin, Stéphane Ciblat, Thomas Pinter, Francis Barabé, Majida El Bakkouri, Paranjay Parikh, Christian Gervais, Agnel Sfeir, Yael Mamane, Stephen J. Morris, W. Cameron Black, Frank Sicheri, Michel Gallant

المصدر: Journal of Medicinal Chemistry. 65:13198-13215

مصطلحات موضوعية: Drug Discovery, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::947c93bf7b6803db8ed4beb935e92af5
https://doi.org/10.1021/acs.jmedchem.2c00998

المؤلفون: W. Cameron Black, Michael Zinda, Jordan T.F. Young, Zuomei Li, Yael Mamane, Rino Stocco, Martine Hamel, Artur Veloso, Victoria Rimkunas, Amina Mulani, Kathryn Skorey, Sabrina Vignini-Hammond, Chloe Fugère-Desjardins, William Yang, Hunain Alam, Amandine Chefson, Shou Yun Yin, Marie-Eve Leclaire, Li Li, Sara Fournier, Lee D. Fader, Stéphane Dorich, Valerie Dumais, Émilie Dumas-Bérube, Charles Pellerin, Alexander Skeldon, Robert Papp, Michal Zimmermann, Anne Roulston

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::062cfaf9177f49a3206feb599326f494
https://doi.org/10.1158/1535-7163.22896018

المؤلفون: W. Cameron Black, Michael Zinda, Jordan T.F. Young, Zuomei Li, Yael Mamane, Rino Stocco, Martine Hamel, Artur Veloso, Victoria Rimkunas, Amina Mulani, Kathryn Skorey, Sabrina Vignini-Hammond, Chloe Fugère-Desjardins, William Yang, Hunain Alam, Amandine Chefson, Shou Yun Yin, Marie-Eve Leclaire, Li Li, Sara Fournier, Lee D. Fader, Stéphane Dorich, Valerie Dumais, Émilie Dumas-Bérube, Charles Pellerin, Alexander Skeldon, Robert Papp, Michal Zimmermann, Anne Roulston

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a51beae2425d617ba7d0ef61e96c7e6
https://doi.org/10.1158/1535-7163.c.6651330.v1

المؤلفون: Anne Roulston, Michal Zimmermann, Robert Papp, Alexander Skeldon, Charles Pellerin, Émilie Dumas-Bérube, Valerie Dumais, Stéphane Dorich, Lee D. Fader, Sara Fournier, Li Li, Marie-Eve Leclaire, Shou Yun Yin, Amandine Chefson, Hunain Alam, William Yang, Chloe Fugère-Desjardins, Sabrina Vignini-Hammond, Kathryn Skorey, Amina Mulani, Victoria Rimkunas, Artur Veloso, Martine Hamel, Rino Stocco, Yael Mamane, Zuomei Li, Jordan T.F. Young, Michael Zinda, W. Cameron Black

المصدر: Molecular Cancer Therapeutics. 21:245-256

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5c5c2c693c809fd51b04d00ce59692a4
https://doi.org/10.1158/1535-7163.mct-21-0615

المؤلفون: Monica, Bubenik, Pavel, Mader, Philippe, Mochirian, Fréderic, Vallée, Jillian, Clark, Jean-François, Truchon, Alexander L, Perryman, Victor, Pau, Igor, Kurinov, Karl E, Zahn, Marie-Eve, Leclaire, Robert, Papp, Marie-Claude, Mathieu, Martine, Hamel, Nicole M, Duffy, Claude, Godbout, Matias, Casas-Selves, Jean-Pierre, Falgueyret, Prasamit S, Baruah, Olivier, Nicolas, Rino, Stocco, Hugo, Poirier, Giovanni, Martino, Alexanne Bonneau, Fortin, Anne, Roulston, Amandine, Chefson, Stéphane, Dorich, Miguel, St-Onge, Purvish, Patel, Charles, Pellerin, Stéphane, Ciblat, Thomas, Pinter, Francis, Barabé, Majida, El Bakkouri, Paranjay, Parikh, Christian, Gervais, Agnel, Sfeir, Yael, Mamane, Stephen J, Morris, W Cameron, Black, Frank, Sicheri, Michel, Gallant

المصدر: Journal of medicinal chemistry. 65(19)

مصطلحات موضوعية: DNA Replication, Ovarian Neoplasms, Mice, Drug Design, Drug Discovery, Animals, Humans, Female, DNA-Directed DNA Polymerase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::531f44b082fb5f00fe6c2f82d97a48bc
https://pubmed.ncbi.nlm.nih.gov/36126059

المؤلفون: Anne Roulston, Michal Zimmerman, Robert Papp, Alex Skeldon, Charles Pellerin, Émilie Dumas-Bérube, Valerie Dumais, Stephane Dorich, Sara Fournier, Li Li, Marie-Ève Leclaire, Shou Yun Yin, Amandine Chefson, Hunain Alam, William Yang, Chloe Fugère-Desjardins, Sabrina Hammond, Kathryn Skorey, Amina Mulani, Victoria Rimkunas, Artur Veloso, Martine Hamel, Rino Stocco, Yael Mamane, Zuomei Li, Jordan Young, Mike Zinda, Cameron Black

المصدر: Molecular Cancer Therapeutics. 20:P054-P054

مصطلحات موضوعية: Cancer Research, Oncology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::64546a898e05e3470c5622263c464f40
https://doi.org/10.1158/1535-7163.targ-21-p054

المؤلفون: Samir Ali, Charles Pellerin, Daniel Lamarre

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://jvi.asm.org/content/78/1/491.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.335.9141; http://jvi.asm.org/content/78/1/491.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.335.9141
http://jvi.asm.org/content/78/1/491.full.pdf

المؤلفون: Ginette Mckercher, Pierre L. Beaulieu, Daniel Lamarre, Steven Laplante, Sylvain Lefebvre, Charles Pellerin, Louise Thauvette, George Kukolj

المساهمون: The Pennsylvania State University CiteSeerX Archives

المصدر: http://nar.oxfordjournals.org/content/32/2/422.full.pdf.

وصف الملف: application/pdf

Relation: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.503.3378; http://nar.oxfordjournals.org/content/32/2/422.full.pdf

الاتاحة: http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.503.3378
http://nar.oxfordjournals.org/content/32/2/422.full.pdf

المؤلفون: Louis Lacombe, Charles Pellerin, Michel Carmel, Armen Aprikian, Ginette McKercher, Simone Chevalier, Fred Saad

المصدر: Biopreservation and biobanking. 14(5)

مصطلحات موضوعية: 0301 basic medicine, Male, Minisatellite Repeat, Sample (material), Medicine (miscellaneous), Computational biology, Minisatellite Repeats, Biology, Polymerase Chain Reaction, General Biochemistry, Genetics and Molecular Biology, law.invention, Specimen Handling, 03 medical and health sciences, 0302 clinical medicine, Tandem repeat, law, Humans, Genotyping, Polymerase chain reaction, Biological Specimen Banks, Genetics, Prostatic Neoplasms, Cell Biology, General Medicine, Biobank, DNA Fingerprinting, Identification (information), 030104 developmental biology, DNA profiling, 030220 oncology & carcinogenesis, Algorithms

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f098f68334194e1d12897dd7479bee6
https://pubmed.ncbi.nlm.nih.gov/27327090

المؤلفون: Ginette McKercher, Sylvain Lefebvre, George Kukolj, Pierre L. Beaulieu, Charles Pellerin, Steven R. LaPlante, Louise Thauvette, Daniel Lamarre

المصدر: Nucleic Acids Research. 32:422-431

مصطلحات موضوعية: viruses, Hepatitis C virus, Drug Evaluation, Preclinical, RNA-dependent RNA polymerase, RNA polymerase II, Hepacivirus, Viral Nonstructural Proteins, Biology, Virus Replication, medicine.disease_cause, Substrate Specificity, Inhibitory Concentration 50, chemistry.chemical_compound, RNA polymerase, Genetics, medicine, Animals, Enzyme Inhibitors, NS5B, Polymerase, virus diseases, RNA, Templates, Genetic, Articles, RNA-Dependent RNA Polymerase, Amides, Molecular biology, digestive system diseases, Kinetics, Poliovirus, chemistry, biology.protein, RNA, Viral, Benzimidazoles, Cattle, RNA Polymerase II, Primer (molecular biology)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a389d027fac34b416d3e86dc8e8ed94a
https://doi.org/10.1093/nar/gkh160

المؤلفون: George Kukolj, Samir Ali, Charles Pellerin, Daniel Lamarre

المصدر: Journal of Virology. 78:491-501

مصطلحات موضوعية: viruses, Hepatitis C virus, Immunology, Genome, Viral, Hepacivirus, Biology, Kidney, Virus Replication, medicine.disease_cause, Microbiology, Cell Line, Cell Fusion, Virology, Tumor Cells, Cultured, medicine, Humans, Replicon, Subgenomic mRNA, Cell fusion, HEK 293 cells, Transfection, biochemical phenomena, metabolism, and nutrition, digestive system diseases, Virus-Cell Interactions, Viral replication, Cell culture, Insect Science, RNA, Viral

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06160d3f3a1b0ba1aead57332135e467
https://doi.org/10.1128/jvi.78.1.491-501.2004

المؤلفون: Gulrez Fazal, Sylvie Goulet, Volkhard Austel, Jean Gauthier, Charles Pellerin, Pierre L. Beaulieu, Steven R. LaPlante, Ginette McKercher, Marc-André Poupart, James Gillard, George Kukolj, Michael Bös, Yves Bousquet, Sylvain Lefebvre

المصدر: Bioorganic & Medicinal Chemistry Letters. 14:119-124

مصطلحات موضوعية: Benzimidazole, Hepacivirus, Hepatitis C virus, Clinical Biochemistry, Pharmaceutical Science, Viral Nonstructural Proteins, medicine.disease_cause, Antiviral Agents, Biochemistry, Virus, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, medicine, Enzyme Inhibitors, Molecular Biology, Polymerase, chemistry.chemical_classification, biology, Organic Chemistry, RNA-Dependent RNA Polymerase, Nucleotidyltransferase, biology.organism_classification, Virology, Enzyme, chemistry, biology.protein, Molecular Medicine, Benzimidazoles, Nucleoside

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::028cfd5fc70618a023732b6e8babde38
https://doi.org/10.1016/j.bmcl.2003.10.023

المؤلفون: George Kukolj, Ivan A. D. Lessard, Mohamed El-Far, Jean-François Fortin, Yoav Peretz, Elizabeth Wardrop, Michael G. Cordingley, Charles Pellerin, Louise Pilote, Richard Bethell, Patrick Salois

المصدر: Journal of Translational Medicine

مصطلحات موضوعية: Adult, CD4-Positive T-Lymphocytes, Male, medicine.drug_class, Immunopotentiation, HIV Infections, Plasma protein binding, CHO Cells, Biology, CD8-Positive T-Lymphocytes, HVEM, Monoclonal antibody, GPI-Linked Proteins, Lymphocyte Activation, Jurkat cells, General Biochemistry, Genetics and Molecular Biology, Jurkat Cells, Cricetulus, Antigens, CD, Cricetinae, PD-1, medicine, Cytotoxic T cell, Animals, Humans, Protein Isoforms, Receptors, Immunologic, Receptor, Medicine(all), Biochemistry, Genetics and Molecular Biology(all), Research, HIV, General Medicine, Ligand (biochemistry), Molecular biology, HIV-1, Cell activation, CD160, Receptors, Tumor Necrosis Factor, Member 14, CD8, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d142de11976c1517729f456803d3505
https://pubmed.ncbi.nlm.nih.gov/25179432

المؤلفون: Pierre L. Beaulieu, Charles Pellerin, James Gillard, George Kukolj, Martin Marquis, Yves Bousquet, Serge Valois, Jean Gauthier, Ginette McKercher

المصدر: Journal of medicinal chemistry. 47(27)

مصطلحات موضوعية: Hepatitis C virus, RNA-dependent RNA polymerase, Hepacivirus, Viral Nonstructural Proteins, medicine.disease_cause, Antiviral Agents, Virus, Structure-Activity Relationship, Allosteric Regulation, Drug Discovery, medicine, Humans, Replicon, Enzyme Inhibitors, Polymerase, Subgenomic mRNA, biology, Chemistry, virus diseases, Nucleotidyltransferase, Virology, digestive system diseases, NS2-3 protease, biology.protein, Molecular Medicine, Benzimidazoles

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::171d768316e86c1783b631e8979c1fe9
https://pubmed.ncbi.nlm.nih.gov/15615537

المؤلفون: Murray D. Bailey, Martine Brault, Daniel Lamarre, Martin Marquis, Ginette McKercher, Charles Pellerin, Lisette Lagacé, Louise Pilote, Diane Thibeault, Arnim Pause, Ted Halmos, Roger Maurice, Florence Dô, George Kukolj

المصدر: The Journal of biological chemistry. 278(22)

مصطلحات موضوعية: Serine Proteinase Inhibitors, medicine.drug_class, viruses, Hepatitis C virus, medicine.medical_treatment, Hepacivirus, Viral Nonstructural Proteins, medicine.disease_cause, Biochemistry, Antiviral Agents, medicine, Humans, Molecular Biology, Subgenomic mRNA, Serine protease, NS3, Protease, biology, Chemistry, virus diseases, RNA, Interferon-alpha, Cell Biology, biochemical phenomena, metabolism, and nutrition, Virology, Molecular biology, Hepatitis C, digestive system diseases, NS2-3 protease, biology.protein, RNA, Viral, Antiviral drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b302722fbfcf949191872c824343ff32
https://pubmed.ncbi.nlm.nih.gov/12646587

المؤلفون: Sylvain Lefebvre, Michael J. Little, Daniel Lamarre, Charles Pellerin, George Kukolj, Ginette McKercher

المصدر: Biochemical and biophysical research communications. 295(3)

مصطلحات موضوعية: Untranslated region, GTP', Molecular Sequence Data, Biophysics, RNA-dependent RNA polymerase, Hepacivirus, Biology, Viral Nonstructural Proteins, Biochemistry, chemistry.chemical_compound, Nucleotide, Cloning, Molecular, Molecular Biology, NS5B, 3' Untranslated Regions, Repetitive Sequences, Nucleic Acid, chemistry.chemical_classification, Base Sequence, Dose-Response Relationship, Drug, Models, Genetic, Reverse Transcriptase Polymerase Chain Reaction, RNA, Cell Biology, Molecular biology, De novo synthesis, chemistry, Polypyrimidine tract, Guanosine Triphosphate, Plasmids

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c66800626bd84f4af491776d6582e2
https://pubmed.ncbi.nlm.nih.gov/12099694

المؤلفون: Peter Tijssen, Charles Pellerin, Susan Moir, Jacqueline Lecomte

المصدر: Veterinary microbiology. 45(1)

مصطلحات موضوعية: Genes, Viral, Molecular Sequence Data, Molecular cloning, Biology, Microbiology, Homology (biology), Genotype, Coding region, Animals, Amino Acid Sequence, Gene, Conserved Sequence, Genetics, chemistry.chemical_classification, Diarrhea Viruses, Bovine Viral, General Veterinary, Base Sequence, Pestivirus, General Medicine, biology.organism_classification, Molecular biology, Amino acid, chemistry, Nucleic acid, Bovine Virus Diarrhea-Mucosal Disease, Cattle

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8efbd88b16621d53c5f47dbce52a7a5c
https://pubmed.ncbi.nlm.nih.gov/7653028