المؤلفون: Mcmahon, Emily, El Sayed, Sherihan, Green, Jack, Hoyle, Christopher, Fitzpatrick, Lorna, Jones, Emma, Corrie, Eve, Kelly, Rebecca, Challinor, Mairi, Freeman, Sally, Bryce, Richard, Lawrence, Catherine B., Brough, David, Kasher, Paul

المصدر: Mcmahon , E , El Sayed , S , Green , J , Hoyle , C , Fitzpatrick , L , Jones , E , Corrie , E , Kelly , R , Challinor , M , Freeman , S , Bryce , R , Lawrence , C B , Brough , D & Kasher , P 2024 , ' Brazilin is a Natural Product Inhibitor of the NLRP3 Inflammasome ' , iScience , vol. 27 , no. 2 , 108968 . https://doi.org/10.1016/j.isci.2024.108968

Relation: https://research.manchester.ac.uk/en/publications/457edbaa-049a-489b-9dc6-f8afc25a6060

الاتاحة: https://research.manchester.ac.uk/en/publications/457edbaa-049a-489b-9dc6-f8afc25a6060
https://doi.org/10.1016/j.isci.2024.108968

المؤلفون: Leung, Leo, Niculescu-Duvaz, Dan, Smithen, Deborah, Lopes, Filipa, Callens, Cedric, McLeary, Robert, Saturno, Grazia, Davies, Lawrence, Aljarah, Mohammed, Brown, Michael, Johnson, Louise, Zambon, Alfonso, Chambers, Tim, Ménard, Delphine, Bayliss, Natasha, Knight, Ruth, Fish, Laura, Lawrence, Rae, Challinor, Mairi, Tang, HaoRan, Marais, Richard, Springer, Caroline

المساهمون: Leung, Leo, Niculescu-Duvaz, Dan, Smithen, Deborah, Lopes, Filipa, Callens, Cedric, Mcleary, Robert, Saturno, Grazia, Davies, Lawrence, Aljarah, Mohammed, Brown, Michael, Johnson, Louise, Zambon, Alfonso, Chambers, Tim, Ménard, Delphine, Bayliss, Natasha, Knight, Ruth, Fish, Laura, Lawrence, Rae, Challinor, Mairi, Tang, Haoran, Marais, Richard, Springer, Caroline

Relation: info:eu-repo/semantics/altIdentifier/pmid/31070916; info:eu-repo/semantics/altIdentifier/wos/WOS:000473251200009; volume:62; issue:12; firstpage:5863; lastpage:5884; journal:JOURNAL OF MEDICINAL CHEMISTRY; http://hdl.handle.net/11380/1179025; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85068132632

الاتاحة: http://hdl.handle.net/11380/1179025
https://doi.org/10.1021/acs.jmedchem.9b00335

المؤلفون: Smithen, Deborah A., Leung, Leo M. H., Challinor, Mairi, Lawrence, Rae, Tang, HaoRan, Niculescu-Duvaz, Dan, Pearce, Simon P., Mcleary, Robert, Lopes, Filipa, Aljarah, Mohammed, Brown, Michael, Johnson, Louise, Thomson, Graeme, Marais, Richard, Springer, Caroline

المساهمون: Institute of Cancer Research, Royal Cancer Hospital, Wellcome Trust, Cancer Research UK

المصدر: Journal of Medicinal Chemistry ; volume 63, issue 5, page 2308-2324 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.9b01112
http://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b01112
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.9b01112

المؤلفون: Lie-A-Ling, Michael, Marinopoulou, Elli, Lilly, Andrew J, Challinor, Mairi, Patel, Rahima, Lancrin, Christophe, Kouskoff, Valerie, Lacaud, Georges

المصدر: Lie-A-Ling , M , Marinopoulou , E , Lilly , A J , Challinor , M , Patel , R , Lancrin , C , Kouskoff , V & Lacaud , G 2018 , ' Regulation of RUNX1 dosage is crucial for efficient blood formation from Hemogenic Endothelium ' , Development . https://doi.org/10.1242/dev.149419

مصطلحات موضوعية: RUNX1, Hemogenic endothelium, Dosage, EHT, CBFβ, SOX7, ResearchInstitutes_Networks_Beacons/mcrc, Manchester Cancer Research Centre

الاتاحة: https://research.manchester.ac.uk/en/publications/398d09dc-3795-4a92-be39-e51ff1440044
https://doi.org/10.1242/dev.149419

المؤلفون: Nowicki-Osuch, Karol, Li, Yaoyong, Challinor, Mairi, Gerrard, David T., Hanley, Neil A., Sharrocks, Andrew D.

المصدر: Nowicki-Osuch , K , Li , Y , Challinor , M , Gerrard , D T , Hanley , N A & Sharrocks , A D 2017 , ' EINCR1 is an EGF inducible lincRNA overexpressed in lung adenocarcinomas ' , PLoS ONE , vol. 12 , no. 7 , e0181902 . https://doi.org/10.1371/journal.pone.0181902

Relation: https://research.manchester.ac.uk/en/publications/fc5de5e4-bd0e-45e4-9195-fb10255798ff

الاتاحة: https://research.manchester.ac.uk/en/publications/fc5de5e4-bd0e-45e4-9195-fb10255798ff
https://doi.org/10.1371/journal.pone.0181902
http://www.scopus.com/inward/record.url?scp=85025430094&partnerID=8YFLogxK

المؤلفون: Goode, Debbie K, Obier, Nadine, Vijayabaskar, M S, Lie-A-Ling, Michael, Lilly, Andrew, Hannah, Rebecca, Lichtinger, Monika, Batta, Kiran, Florkowska, Magdalena, Patel, Rahima, Challinor, Mairi, Wallace, Kirstie, Gilmour, Jane, Assi, Salam A, Cauchy, Pierre, Hoogenkamp, Maarten, Westhead, David R, Lacaud, Georges, Kouskoff, Valerie, Göttgens, Berthold, Bonifer, Constanze

المصدر: Goode , D K , Obier , N , Vijayabaskar , M S , Lie-A-Ling , M , Lilly , A , Hannah , R , Lichtinger , M , Batta , K , Florkowska , M , Patel , R , Challinor , M , Wallace , K , Gilmour , J , Assi , S A , Cauchy , P , Hoogenkamp , M , Westhead , D R , Lacaud , G , Kouskoff , V , Göttgens , B & Bonifer , C 2016 , ' Dynamic Gene Regulatory Networks Drive Hematopoietic Specification and Differentiation ....

مصطلحات موضوعية: Animals, Cell Differentiation, Cell Lineage, Embryonic Stem Cells, Gene Expression Regulation, Developmental, Gene Regulatory Networks, Hematopoiesis, Hematopoietic Stem Cells, Homeodomain Proteins, Mice, Protein Binding, Transcription Factors, Journal Article, Research Support, Non-U.S. Gov't, ResearchInstitutes_Networks_Beacons/mcrc, name=Manchester Cancer Research Centre

الاتاحة: https://research.manchester.ac.uk/en/publications/e74b7e62-3577-4941-96f1-3ad80179ccb6
https://doi.org/10.1016/j.devcel.2016.01.024

المؤلفون: Callis, Rowena, Rabow, Alfred, Tonge, Michael, Bradbury, Robert, Challinor, Mairi, Roberts, Karen, Jones, Karen, Walker, Graeme

المصدر: SLAS Discovery ; volume 20, issue 6, page 748-759 ; ISSN 2472-5552

الاتاحة: http://dx.doi.org/10.1177/1087057115580298
http://journals.sagepub.com/doi/pdf/10.1177/1087057115580298
http://journals.sagepub.com/doi/full-xml/10.1177/1087057115580298
https://api.elsevier.com/content/article/PII:S2472555222072495?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S2472555222072495?httpAccept=text/plain

المؤلفون: Smithen, Deborah A., Leung, Leo M. H., Challinor, Mairi, Lawrence, Rae, Tang, HaoRan, Niculescu-Duvaz, Dan, Pearce, Simon P., Mcleary, Robert, Lopes, Filipa, Aljarah, Mohammed, Brown, Michael, Johnson, Louise, Thomson, Graeme, Marais, Richard, Springer, Caroline

المصدر: Journal of Medicinal Chemistry; March 2020, Vol. 63 Issue: 5 p2308-2324, 17p

المؤلفون: Ward, Richard A., Colclough, Nicola, Challinor, Mairi, Debreczeni, Judit E., Eckersley, Kay, Fairley, Gary, Feron, Lyman, Flemington, Vikki, Graham, Mark A., Greenwood, Ryan, Hopcroft, Philip, Howard, Tina D., James, Michael, Jones, Clifford D., Jones, Christopher R., Renshaw, Jonathan, Roberts, Karen, Snow, Lindsay, Tonge, Michael, Yeung, Kay

المصدر: Journal of Medicinal Chemistry ; volume 58, issue 11, page 4790-4801 ; ISSN 0022-2623 1520-4804

الاتاحة: http://dx.doi.org/10.1021/acs.jmedchem.5b00466
https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5b00466