المؤلفون: Arpan Dey, Aditi Verma, Uchit Bhaskar, Bidyut Sarkar, Mamata Kallianpur, Vicky Vishvakarma, Anand Kant Das, Kanchan Garai, Odity Mukherjee, Kunihiko Ishii, Tahei Tahara, Sudipta Maiti

مصطلحات موضوعية: Biophysics, Biochemistry, Cell Biology, Neuroscience, Biotechnology, Cancer, Hematology, Infectious Diseases, Chemical Sciences not elsewhere classified, Physical Sciences not elsewhere classified, quantitative cellular assay, patients also exhibit, major unsolved puzzle, although intracellular interactions, cellular apoe content, ad drug discovery, apoe interaction suppresses, fluorescence lifetime changes, fluorescence lifetime, intracellular interaction, toxicogenic interaction, apoe variants, apoe modifies, understanding ad, tau proteins, specific changes, membrane affinity, live cells, inducing changes, directly imaged

Relation: https://figshare.com/articles/journal_contribution/A_Toxicogenic_Interaction_between_Intracellular_Amyloid_and_Apolipoprotein_E/25318045

الاتاحة: https://doi.org/10.1021/acschemneuro.4c00048.s001
https://figshare.com/articles/journal_contribution/A_Toxicogenic_Interaction_between_Intracellular_Amyloid_and_Apolipoprotein_E/25318045

المؤلفون: Wencheng Zhao, Huizi Cui, Kaifeng Liu, Xiaotang Yang, Shu Xing, Wannan Li

المصدر: International Journal of Molecular Sciences, Vol 25, Iss 7, p 3654 (2024)

مصطلحات موضوعية: network pharmacology, LC–MS, cellular assay, molecular docking, PTP1B, anti-diabetic mechanisms, Biology (General), QH301-705.5, Chemistry, QD1-999

Relation: https://www.mdpi.com/1422-0067/25/7/3654; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067; https://doaj.org/article/c1df91ae44bd4bc28b8b7a09cba51969

الاتاحة: https://doi.org/10.3390/ijms25073654
https://doaj.org/article/c1df91ae44bd4bc28b8b7a09cba51969

المؤلفون: Fredlender, Callie

مصطلحات موضوعية: Pharmaceutical sciences, Cellular assay, Degradation, DEL, DNA-encoded libraries, drug discovery, TPD

URL الوصول: https://escholarship.org/uc/item/531527vn

المؤلفون: Aixiao Li, Ahmed Bouhss, Marie-Jeanne Clément, Cyril Bauvais, J. Paul Taylor, Guillaume Bollot, David Pastré

المصدر: Frontiers in Molecular Biosciences, Vol 10 (2023)

مصطلحات موضوعية: targeting RNA: protein interaction, RNA-binding proteins, small molecules, drug screening, cellular assay, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2023.1298441/full; https://doaj.org/toc/2296-889X

URL الوصول: https://doaj.org/article/22c47e5584934302a02e842601707265

المؤلفون: Lopez, Ludivine, de Waard, Stephan, Meudal, Hervé, Caumes, Cécile, Khakh, Kuldip, Peigneur, Steve, Oliveira-Mendes, Barbara, Lin, Sophia, de Waele, Jolien, Montnach, Jérôme, Cestèle, Sandrine, Tessier, Agnès, Johnson, J.P., Mantegazza, Massimo, Tytgat, Jan, Cohen, Charles, Béroud, Rémy, Bosmans, Frank, Landon, Céline, de Waard, Michel

المساهمون: ITX-lab unité de recherche de l'institut du thorax UMR1087 UMR6291 (ITX-lab), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Nantes Université - UFR de Médecine et des Techniques Médicales (Nantes Univ - UFR MEDECINE), Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ)-Nantes Université - pôle Santé, Nantes Université (Nantes Univ)-Nantes Université (Nantes Univ), Centre de biophysique moléculaire (CBM), Université d'Orléans (UO)-Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS), Universiteit Gent = Ghent University = Université de Gand (UGENT), Institut de pharmacologie moléculaire et cellulaire (IPMC), Université Nice Sophia Antipolis (1965 - 2019) (UNS)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UniCA), ANR-11-LABX-0015,ICST,Canaux ioniques d'intérêt thérapeutique(2011), ANR-21-CE18-0042,Nav12RESCUE,Restauration des fonctions du canal sodique Nav1.2 dans des troubles neurodéveloppementaux graves(2021)

المصدر: ISSN: 0753-3322.

مصطلحات موضوعية: Drug discovery, JzTx-34, Pharmacology, hNa v 1.1 channel, Biophysics, High-throughput screening, Automated patch clamp, Cellular assay, Peptide synthesis, Lead optimization, Structural functional relationships, Dravet disease, [CHIM.THER]Chemical Sciences/Medicinal Chemistry, [SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/Pharmacology

الاتاحة: https://hal.science/hal-04224866
https://hal.science/hal-04224866v1/document
https://hal.science/hal-04224866v1/file/Lopez2023.pdf
https://doi.org/10.1016/j.biopha.2023.115173

المؤلفون: Dawid Głów, Simon Meyer, Irene García Roldán, Lara Marie Akingunsade, Kristoffer Riecken, Boris Fehse

المصدر: Molecular Therapy: Methods & Clinical Development, Vol 22, Iss , Pp 249-262 (2021)

مصطلحات موضوعية: CRISPR/Cas, genome editing, off-targets, side effects, gene therapy, cellular assay, Genetics, QH426-470, Cytology, QH573-671

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050121001212; https://doaj.org/toc/2329-0501

URL الوصول: https://doaj.org/article/6f33396e84f94dfc9ac886fa0a5d9a8b

المؤلفون: Huifen Ding, Sunil George, Xiaoyan Iris Leng, Michael Ihnat, Jian-Xing Ma, Guochun Jiang, David Margolis, Julie Dumond, Yuanyuan Zhang

المصدر: Materials Today Advances, Vol 15, Iss , Pp 100261- (2022)

مصطلحات موضوعية: Mitochondrial toxicity, Antiviral drugs, 3D cellular assay, Human stem cells, Silk fibers, Spheroids, Materials of engineering and construction. Mechanics of materials, TA401-492

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2590049822000571; https://doaj.org/toc/2590-0498

URL الوصول: https://doaj.org/article/1b533cd54a144ea1a07e7619b2345fac

المؤلفون: Shropshire, Ian Michael

مصطلحات موضوعية: 616.99, Herceptin®, Trastuzumab, in use stability, physicochemical techniques, cellular assay

URL الوصول: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.694987

المؤلفون: Jessen, Stine Bull, Özkul, Derya Coskun, Özen, Yasemin, Gögenur, Ismail, Troelsen, Jesper T.

المصدر: Jessen , S B , Özkul , D C , Özen , Y , Gögenur , I & Troelsen , J T 2022 , ' Establishment of a luciferase-based method for measuring cancer cell adhesion and proliferation ' , Analytical Biochemistry , vol. 650 , 114723 . https://doi.org/10.1016/j.ab.2022.114723

مصطلحات موضوعية: Cancer cell lines, Cell adhesion, Cell proliferation, Cellular assay, CRISPR, Luciferase

وصف الملف: application/pdf

الاتاحة: https://forskning.ruc.dk/da/publications/b3e7c494-a624-49b4-ab39-c4f85c7788b5
https://doi.org/10.1016/j.ab.2022.114723
https://hdl.handle.net/1800/b3e7c494-a624-49b4-ab39-c4f85c7788b5
https://rucforsk.ruc.dk/ws/files/81336417/1_s2.0_S0003269722001798_main.pdf

المؤلفون: Linhartova, Lucie, Costet, Nathalie, Pakdel, Farzad, Cajthaml, Tomas, Habauzit, Denis

المساهمون: Institute of Microbiology of the Czech Academy of Sciences Prague, Czech Republic (MBU / CAS), Czech Academy of Sciences Prague (CAS), Univerzita Karlova Praha, Česká republika = Charles University Prague, Czech Republic (UK), Institut de recherche en santé, environnement et travail (Irset), Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique EHESP (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Laboratoire de Fougères - ANSES, Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail (ANSES), Czech Science Foundation Grant number 20-14318Y

المصدر: ISSN: 0260-437X.

مصطلحات موضوعية: toxicology, toxicity, in-vitro test, environment, pollution, estrogen, bioassay, T47D cell lines, Cytokine CXCL12/SDF1, Estrogenic activity cellular assay, T47D, material variability, multivariate linear model (MLM), ecotoxciology, Analytical tools, toxicologie, toxicité, test in-vitro, environnement, oestrogène, hormone, écotoxicologie, bioessai, cellule T47D, modèle linéaire multivarié, Méthodes analytiques, MESH: Biological Assay, MESH: Cytokines, MESH: Estrogens, MESH: Water Pollutants

Relation: info:eu-repo/semantics/altIdentifier/pmid/34964157; anses-03512680; https://anses.hal.science/anses-03512680; https://anses.hal.science/anses-03512680/document; https://anses.hal.science/anses-03512680/file/Linhartova%20et%20al-2021-Key%20parameter%20optimization%20using%20multivariable%20linear%20model%20for%20the%20evaluation.pdf; PUBMED: 34964157

الاتاحة: https://anses.hal.science/anses-03512680
https://anses.hal.science/anses-03512680/document
https://anses.hal.science/anses-03512680/file/Linhartova%20et%20al-2021-Key%20parameter%20optimization%20using%20multivariable%20linear%20model%20for%20the%20evaluation.pdf
https://doi.org/10.1002/jat.4280

المؤلفون: Jaron, Marcel, Lehky, Michael, Zarà, Marta, Zaydowicz, Chris Nicole, Lak, Aidin, Ballmann, Rico, Heine, Philip Alexander, Wenzel, Esther Veronika, Schneider, Kai-Thomas, Bertoglio, Federico, Kempter, Susanne, Köster, Reinhard Wolfgang, Barbieri, Silvia Stella, van den Heuvel, Joop, Hust, Michael, Dübel, Stefan, Schubert, Maren

المصدر: Viruses : Special Issue Virus-Like Particle Vaccines 2022 14 (2022) 10, 2087. - https://doi.org/10.3390/v14102087 -- Viruses -- http://www.mdpi.com/journal/viruses -- https://www.ncbi.nlm.nih.gov/pmc/journals/1559/ -- http://www.bibliothek.uni-regensburg.de/ezeit/?2516098 -- 1999-4915 -- 1999-4915

مصطلحات موضوعية: Article, ddc:660.6, ddc:579, Veröffentlichung der TU Braunschweig, Publikationsfonds der TU Braunschweig, Animals, Humans, Baculoviridae, Angiotensin II, Antibodies, Monoclonal, Spike Glycoprotein, Coronavirus, Insecta, COVID-19, Angiotensin-Converting Enzyme 2, SARS-CoV-2, Expression vector, Insect cells, Virus-like Particles (Vlps), Cellular Assay

وصف الملف: 16 Seiten

Relation: https://doi.org/10.3390/v14102087; https://nbn-resolving.org/urn:nbn:de:gbv:084-2023011008546; https://leopard.tu-braunschweig.de/receive/dbbs_mods_00071835; https://leopard.tu-braunschweig.de/servlets/MCRFileNodeServlet/dbbs_derivate_00050473/Schubert_viruses-14-02087-v2.pdf; http://publikationsserver.tu-braunschweig.de/get/71835; https://www.mdpi.com/1999-4915/14/10/2087/pdf?version=1663926882

الاتاحة: https://doi.org/10.3390/v14102087
https://nbn-resolving.org/urn:nbn:de:gbv:084-2023011008546
https://leopard.tu-braunschweig.de/receive/dbbs_mods_00071835
https://leopard.tu-braunschweig.de/servlets/MCRFileNodeServlet/dbbs_derivate_00050473/Schubert_viruses-14-02087-v2.pdf
http://publikationsserver.tu-braunschweig.de/get/71835
https://www.mdpi.com/1999-4915/14/10/2087/pdf?version=1663926882

المؤلفون: Delompré, Thomas, Belloir, Christine, Martin, Christophe, Salles, Christian, Briand, Loïc

المساهمون: Centre des Sciences du Goût et de l'Alimentation Dijon (CSGA), Université de Bourgogne (UB)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro Dijon, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Université Bourgogne Franche-Comté COMUE (UBFC), Bayer Healthcare SAS, National Agency for Research and Technology (ANRT-CIFRE 2017/1418), Association Nationale de la Recherche et de la Technologie (ANRT), European Regional Development Fund (ERDF), Conseil régional de Bourgogne-Franche-Comté.

المصدر: ISSN: 2072-6643 ; Nutrients ; https://hal.inrae.fr/hal-03819551 ; Nutrients, 2022, 14 (19), pp.4141. ⟨10.3390/nu14194141⟩ ; https://www.mdpi.com/2072-6643/14/19/4141.

مصطلحات موضوعية: vitamins, bitter taste, TAS2R, cellular assay, sensory analysis, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology

Relation: info:eu-repo/semantics/altIdentifier/pmid/36235793; hal-03819551; https://hal.inrae.fr/hal-03819551; https://hal.inrae.fr/hal-03819551/document; https://hal.inrae.fr/hal-03819551/file/delompre_2022_vol_14_4141_nutrients.pdf; PUBMED: 36235793; PUBMEDCENTRAL: PMC9571608; WOS: 000867043300001

الاتاحة: https://hal.inrae.fr/hal-03819551
https://hal.inrae.fr/hal-03819551/document
https://hal.inrae.fr/hal-03819551/file/delompre_2022_vol_14_4141_nutrients.pdf
https://doi.org/10.3390/nu14194141

المؤلفون: Delompré, Thomas, Belloir, Christine, Salles, Christian, Briand, Loïc

مصطلحات موضوعية: vitamins, bitter, bitter taste threshold, cellular assay, sensory studies

Relation: https://zenodo.org/communities/weurman2021; https://doi.org/10.5281/zenodo.5617494; https://doi.org/10.5281/zenodo.5617495; oai:zenodo.org:5617495

الاتاحة: https://doi.org/10.5281/zenodo.5617495

المؤلفون: Zand Z, Khaki PA, Salihi A, Sharifi M, Qadir Nanakali NM, Alasady AAB, Aziz FM, Shahpasand K, Hasan A, Falahati M

المصدر: International Journal of Nanomedicine, Vol Volume 14, Pp 6989-7000 (2019)

مصطلحات موضوعية: cerium oxide, nanoparticle, amyloid, cytotoxicity, spectroscopy, cellular assay, inhibition, Medicine (General), R5-920

وصف الملف: electronic resource

Relation: https://www.dovepress.com/cerium-oxide-nps-mitigate-the-amyloid-formation-of-alpha-synuclein-and-peer-reviewed-article-IJN; https://doaj.org/toc/1178-2013

URL الوصول: https://doaj.org/article/54ddc45677384dcfbb01214829ef23ca

المؤلفون: Tatiana Y. Hargrove (11766632), Zdzislaw Wawrzak (1330530), Girish Rachakonda (619635), W. David Nes (2375191), Fernando Villalta (316343), F. Peter Guengerich (272072), Galina I. Lepesheva (1330527)

مصطلحات موضوعية: Biochemistry, Pharmacology, Biotechnology, Cancer, Infectious Diseases, Virology, Chemical Sciences not elsewhere classified, relaxed substrate requirements, potential drug candidates, including catalytic properties, experimental substituted azoles, clinical antifungal drugs, amoeba makes sterols, fowleri cellular assay, 35 μm ), fowleri sterol 14, sterol biosynthesis inhibitors, also provides insight, 50 , inhibition naegleria fowleri, naegleria fowleri, sterol 14α, potent inhibitors, 69 μm, suggests directions, strongest inhibitor, protozoan pathogen, lower sensitivity, low toxicity, highest potencies

Relation: https://figshare.com/articles/journal_contribution/Relaxed_Substrate_Requirements_of_Sterol_14_-Demethylase_from_Naegleria_fowleri_Are_Accompanied_by_Resistance_to_Inhibition/17092088

الاتاحة: https://doi.org/10.1021/acs.jmedchem.1c01710.s001

المؤلفون: Yuki Ohmuro-Matsuyama (1844242), Tetsuya Kitaguchi (588172), Hiroshi Kimura (3849), Hiroshi Ueda (52356)

مصطلحات موضوعية: Biochemistry, Cell Biology, Genetics, Molecular Biology, Neuroscience, Pharmacology, Biotechnology, Cancer, Virology, Chemical Sciences not elsewhere classified, autism spectrum disorder, H 3K levels, Intrabodies Histone deacetylase, YFP fragment FP 1-10, cell viability test, fragment FP 11, H 3K, split YFP reporter system, HDAC inhibitors, HDAC inhibitor activities, Simple Fluorogenic Cellular Assay, Histone Deacetylase Inhibitors, H 3K intrabody, histone H 3

Relation: https://figshare.com/articles/journal_contribution/Simple_Fluorogenic_Cellular_Assay_for_Histone_Deacetylase_Inhibitors_Based_on_Split-Yellow_Fluorescent_Protein_and_Intrabodies/14384435

الاتاحة: https://doi.org/10.1021/acsomega.0c06281.s001

المؤلفون: Sendino Mouliet, Maria, Omaetxebarria Ibarra, Miren Josu, Prieto Agujeta, Gorka, Rodríguez Pérez, José Antonio

مصطلحات موضوعية: CRM1, XPO1, NES, micropeptide, cellular assay, nuclear export, nuclear export signal

Relation: info:eu-repo/grantAgreement/MINECO/SAF2014-57743-R; https://www.mdpi.com/1422-0067/21/17/6341; International Journal of Molecular Sciences 21(17) : (2020) // Article ID 6341; http://hdl.handle.net/10810/46291

الاتاحة: http://hdl.handle.net/10810/46291
https://doi.org/10.3390/ijms21176341

المؤلفون: Elizabeth Terry-Kantor, Arati Tripathi, Thibaut Imberdis, Zachary M. LaVoie, Gary P. H. Ho, Dennis Selkoe, Saranna Fanning, Nagendran Ramalingam, Ulf Dettmer

المصدر: International Journal of Molecular Sciences; Volume 21; Issue 15; Pages: 5193

مصطلحات موضوعية: alpha-synuclein, protein misfolding, Parkinson’s disease, Lewy body dementia, neurotoxicity, stearoyl-CoA desaturase, cellular assay

جغرافية الموضوع: agris

وصف الملف: application/pdf

Relation: Molecular Toxicology; https://dx.doi.org/10.3390/ijms21155193

الاتاحة: https://doi.org/10.3390/ijms21155193

المؤلفون: Katie Morgan, Wesam Gamal, Kay Samuel, Steven D. Morley, Peter C. Hayes, Pierre Bagnaninchi, John N. Plevris

المصدر: Journal of Clinical Medicine; Volume 9; Issue 1; Pages: 50

مصطلحات موضوعية: impedance based cellular assay, ECIS, xCELLigence, TEER, liver, hepatology

وصف الملف: application/pdf

Relation: Gastroenterology & Hepatopancreatobiliary Medicine; https://dx.doi.org/10.3390/jcm9010050

الاتاحة: https://doi.org/10.3390/jcm9010050

المؤلفون: Srinath Pashikanti, Farjana Afrin, Trevor C. Meldrum, John L. Stegelmeier, Adriene Pavek, Yashar A. Habashi, Kaniz Fatema, Jared J. Barrott

المصدر: Methods and Protocols; Volume 2; Issue 3; Pages: 76

مصطلحات موضوعية: ceramide, synovial sarcoma, osteosarcoma, sphingomyelin synthase inhibitor, jaspine B, cellular assay

وصف الملف: application/pdf

Relation: https://dx.doi.org/10.3390/mps2030076

الاتاحة: https://doi.org/10.3390/mps2030076