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1Academic Journal
المؤلفون: Sergeev, Eugenia, Hojgaard Hansen, Anders, Pandey, Sunil K, Mackenzie, Amanda E, Hudson, Brian D, Ulven, Trond, Milligan, Graeme
المصدر: Sergeev , E , Hojgaard Hansen , A , Pandey , S K , Mackenzie , A E , Hudson , B D , Ulven , T & Milligan , G 2016 , ' Non-equivalence of key positively charged residues of the free fatty acid 2 receptor in the recognition and function of agonist versus antagonist ligands ' , Journal of Biological Chemistry , vol. 291 , no. 1 , pp. 303-317 . https://doi.org/10.1074/jbc.M115.687939
مصطلحات موضوعية: Amino Acids/metabolism, Binding Sites, Binding, Competitive, Butyrates/chemistry, Butyric Acid/pharmacology, Esters/metabolism, HEK293 Cells, Humans, Kinetics, Ligands, Models, Molecular, Mutant Proteins/chemistry, Receptors, Cell Surface/agonists, Thiophenes/chemistry, Tritium/metabolism
وصف الملف: application/pdf
الاتاحة: https://portal.findresearcher.sdu.dk/da/publications/535cde8e-8617-49fe-9cc8-7b490477430b
https://doi.org/10.1074/jbc.M115.687939
https://findresearcher.sdu.dk/ws/files/124859184/Non_equivalence_of_key_positively_charged_residues_of_the_free_fatty_acid_2_receptor_in_the_recognition_and_function_of_agonist_versus_antagonist_ligands.pdf -
2Academic Journal
المساهمون: Mi H. Kim, Hyung S. Yoo, Young D. Jung, Bong W. Ahn, Boo A. Shin, Kyung K. Kim, Hyeong R. Kim, Min K. Baek, Hee J. Jang, Kim, Mi Young
مصطلحات موضوعية: Acetylcysteine/pharmacology, Carcinoma/enzymology, Carcinoma/microbiology, Carcinoma/pathology, Free Radical Scavengers/pharmacology, Helicobacter pylori, Humans, NF-kappa B/antagonists & inhibitors, NF-kappa B/metabolism, Neoplasm Invasiveness, Nitriles/pharmacology, Reactive Oxygen Species/metabolism, Receptors, Cell Surface/agonists, Urokinase Plasminogen Activator, Signal Transduction, Stomach Neoplasms/enzymology, Stomach Neoplasms/microbiology, Stomach Neoplasms/pathology, Sulfones/pharmacology, Tumor Cells, Cultured, helicobacter pylori, urokinase plasminogen activator receptor, reactive oxygen species, NF-觀B, gastric cancer
وصف الملف: 689~697
Relation: INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE; J01132; OAK-2007-02399; https://ir.ymlib.yonsei.ac.kr/handle/22282913/96172; http://www.spandidos-publications.com/ijmm/19/4/689; T200705723; INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, Vol.19(4) : 689-697, 2007
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3Academic Journal
المؤلفون: Hoveyda, Hamid R, Fraser, Graeme L, Zoute, Ludivine, Dutheuil, Guillaume, Schils, Didier, Brantis, Cyrille, Lapin, Alexey, Parcq, Julien, Guitard, Sandra, Lenoir, François, Bousmaqui, Mohamed El, Rorive, Sarah, Hospied, Sandrine, Blanc, Sébastien, Bernard, Jérôme, Ooms, Frédéric, McNelis, Joanne C, Olefsky, Jerrold M
المصدر: Bioorganic and Medicinal Chemistry, 26 (18), 5169 - 5180 (2018-10-01)
مصطلحات موضوعية: FFA2 agonist, Fsp(3), GPCR, GPR43 agonist, LLE, OGTT, FFA2R protein, human, Receptors, Cell Surface, Thiazoles, Animals, Diabetes Mellitus, Experimental/drug therapy, Dose-Response Relationship, Drug, Humans, Mice, Mice, Knockout, Molecular Structure, Rats, Receptors, Cell Surface/agonists, Receptors, Cell Surface/deficiency, Receptors, Cell Surface/metabolism, Structure-Activity Relationship, Thiazoles/chemistry, Thiazoles/pharmacology, Disease Models, Animal, Drug Discovery, Diabetes Mellitus, Experimental, Biochemistry, Molecular Medicine, Molecular Biology, Pharmaceutical Science, Clinical Biochemistry, Organic Chemistry, Physical, chemical, mathematical & earth Sciences, Chemistry, Physique, chimie, mathématiques & sciences de la terre, Chimie
Relation: https://api.elsevier.com/content/article/PII:S096808961830110X?httpAccept=text/xml; urn:issn:0968-0896; urn:issn:1464-3391
URL الوصول: https://orbi.uliege.be/handle/2268/320297
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4
المؤلفون: Patrick Vanderheyden, Nerdjes Benachour
المساهمون: Department of Bio-engineering Sciences, Experimental Pharmacology, Molecular and Biochemical Pharmacology, Faculty of Sciences and Bioengineering Sciences
المصدر: Bioorganicmedicinal chemistry letters. 27(16)
مصطلحات موضوعية: 0301 basic medicine, Receptors, Cell Surface/agonists, Dipeptidyl Peptidase 4, Clinical Biochemistry, Pharmaceutical Science, Receptors, Cell Surface, Plasma protein binding, Ligands, Biochemistry, Receptor, Angiotensin, Type 1, 03 medical and health sciences, 0302 clinical medicine, Angiotensin II Type 1 Receptor Blockers/chemistry, Drug Discovery, Humans, Receptor, Molecular Biology, G protein-coupled receptor, chemistry.chemical_classification, Receptor, Angiotensin, Type 1/chemistry, Dipeptidyl-Peptidase IV Inhibitors, Dipeptidyl Peptidase 4/chemistry, Organic Chemistry, Dipeptidyl-Peptidase IV Inhibitors/chemistry, Receptor–ligand kinetics, In vitro, Kinetics, 030104 developmental biology, Enzyme, chemistry, Biophysics, Molecular Medicine, Target protein, Signal transduction, Angiotensin II Type 1 Receptor Blockers, 030217 neurology & neurosurgery, Protein Binding, Signal Transduction
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5
المؤلفون: Betten, Åsa, 1967, Dahlgren, Claes, 1949, Hermodsson, Svante, 1934, Hellstrand, Kristoffer, 1956
المصدر: Scand J Immunol. 58(3):321-6
مصطلحات موضوعية: Medical and Health Sciences, Medicin och hälsovetenskap, Chemotactic Factors/immunology/pharmacology, Cytoplasmic Granules/drug effects/immunology, Down-Regulation, Enzyme Inhibitors/immunology/pharmacology, Histamine/immunology/*pharmacology, Humans, N-Formylmethionine Leucyl-Phenylalanine/immunology/pharmacology, NADPH Oxidase/*antagonists & inhibitors/immunology, Neutrophils/drug effects/*enzymology/immunology, Oligopeptides/immunology/*pharmacology, Receptors, Cell Surface/*agonists/immunology, *Receptors, Formyl Peptide, Lipoxin, Research Support, Non-U.S. Gov't, Signal Transduction/drug effects, Superoxides/immunology/*metabolism, Tetradecanoylphorbol Acetate/immunology/pharmacology
URL الوصول: https://gup.ub.gu.se/publication/40820
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6Academic Journal
المؤلفون: Hudson, Brian D, Due-Hansen, Maria E, Christiansen, Elisabeth, Hansen, Anna, Mackenzie, Amanda E, Murdoch, Hannah, Pandey, Sunil K, Ward, Richard J, Marquez, Rudi, Tikhonova, Irina G, Ulven, Trond, Milligan, Graeme
المصدر: Hudson , B D , Due-Hansen , M E , Christiansen , E , Hansen , A , Mackenzie , A E , Murdoch , H , Pandey , S K , Ward , R J , Marquez , R , Tikhonova , I G , Ulven , T & Milligan , G 2013 , ' Defining the molecular basis for the first potent and selective orthosteric agonists of the FFA2 free fatty acid receptor ' , Journal of Biological Chemistry , vol. 288 , pp. 17296-17312 . https://doi.org/10.1074/jbc.M113.455337
مصطلحات موضوعية: Adipocytes/drug effects, Allosteric Regulation, Amino Acid Motifs, Amino Acid Substitution, Animals, Benzeneacetamides/pharmacology, Binding Sites, Butyrates/pharmacology, Cyclopropanes/chemistry, Enteroendocrine Cells/metabolism, Glucagon-Like Peptide 1/metabolism, Guanosine 5'-O-(3-Thiotriphosphate)/metabolism, HEK293 Cells, Humans, Lipolysis/drug effects, Mice, Models, Molecular, Mutagenesis, Site-Directed, Protein Binding, Protein Structure, Tertiary, Rats, Receptors, Cell Surface/agonists, Thiazoles/chemistry
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7Academic Journal
المؤلفون: Hudson, Brian D, Ulven, Trond, Milligan, Graeme
المصدر: Hudson , B D , Ulven , T & Milligan , G 2013 , ' The therapeutic potential of allosteric ligands for free fatty acid sensitive GPCRs ' , Current Topics in Medicinal Chemistry , vol. 13 , no. 1 , pp. 14-25 . https://doi.org/10.2174/1568026611313010004
مصطلحات موضوعية: Allosteric ligand, FFA1-3, Free fatty acid, GPCR, GPR120 orthosteric ligand, GPR84, Inflammation/prevention & control, Allosteric Regulation, Humans, Drugs, Investigational/pharmacology, Receptors, G-Protein-Coupled/agonists, Cell Surface/agonists, Metabolic Diseases/drug therapy, Allosteric Site, Drug Design, Fatty Acids, Nonesterified/chemistry, Ligands
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8Academic Journal
المؤلفون: Gilliet, M., Conrad, C., Geiges, M., Cozzio, A., Thürlimann, W., Burg, G., Nestle, F.O., Dummer, R.
المصدر: Archives of Dermatology, vol. 140, no. 12, pp. 1490-1495
مصطلحات موضوعية: Administration, Topical, Aminoquinolines/administration & dosage, Aminoquinolines/adverse effects, Biopsy, Dendritic Cells/pathology, Diagnostic Errors, Fluorescent Antibody Technique, Humans, Immunohistochemistry, Interferon Inducers/administration & dosage, Interferon Inducers/adverse effects, Male, Membrane Glycoproteins/agonists, Middle Aged, Plasma Cells/pathology, Psoriasis/drug therapy, Psoriasis/pathology, Receptors, Cell Surface/agonists, Skin/pathology, Stem Cells/pathology, Toll-Like Receptor 7, Toll-Like Receptors
Relation: info:eu-repo/semantics/altIdentifier/pmid/15611427; info:eu-repo/semantics/altIdentifier/pissn/0003-987X; https://serval.unil.ch/notice/serval:BIB_E9FD87CF4E27
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9Academic Journal
المؤلفون: Costagliola, Sabine, Panneels, Valérie, Bonomi, M, Koch, J, Many, Marie-Christine, Smits, Guillaume, Vassart, Gilbert
المصدر: EMBO journal, 21 (4
مصطلحات موضوعية: Sciences bio-médicales et agricoles, Amino Acid Sequence, Animals, Antibodies, Monoclonal -- chemistry, Monoclonal -- immunology, Autoantibodies -- immunology, Epitopes -- chemistry, Humans, Immunohistochemistry, Molecular Sequence Data, Receptors, Cell Surface -- agonists, Cell Surface -- chemistry, Cell Surface -- immunology, Cell Surface -- metabolism, Sequence Homology, Amino Acid, Sulfuric Acids -- metabolism, Tyrosine -- metabolism, Glycoprotein, GPCR, Hormones, Sulfation, Tyrosine
وصف الملف: 2 full-text file(s): application/pdf | application/pdf
Relation: uri/info:doi/10.1093/emboj/21.4.504; uri/info:pmid/11847099; uri/info:scp/0037084011; uri/info:pmcid/PMC125869; https://dipot.ulb.ac.be/dspace/bitstream/2013/52368/5/52368.pdf; https://dipot.ulb.ac.be/dspace/bitstream/2013/52368/6/PMC125869.pdf; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/52368