المؤلفون: Diemar, Michael, Onderzoeker, Vinken, Mathieu, Onderzoeker, Teunis, Marc, Onderzoeker, Krul, Cyrille, Lector, Busquet, François, Onderzoeker, Zajac, Julia Dominika, Onderzoeker, Kandarova, Helena, Onderzoeker, Corvi, Raffaella, Onderzoeker, Rosso, Matteo Z, Onderzoeker, Kharina, Anastasiia, Onderzoeker, Stab Bryndum, Louise, Onderzoeker, Santillo, Michael, Onderzoeker, Bloch, Denise, Onderzoeker, Kucheryavenko, Olena, Onderzoeker, Panagiotakos, Demosthenes, Onderzoeker, Rogiers, Vera, Onderzoeker, Beekhuijzen, Manon, Onderzoeker, Giusti, Arianna, Onderzoeker, Najjar, Abdulkarim, Onderzoeker, Courage, Carol, Onderzoeker, Koenig, Torben, Onderzoeker, Kolle, Susanne, Onderzoeker, Boonen, Harrie, Onderzoeker, Dhalluin, Stephane, Onderzoeker, Boberg, Julie, Onderzoeker, Müller, Boris P, Onderzoeker, Kukic, Predrag, Onderzoeker, Ritskes-Hoitinga, Merel, Onderzoeker, Grasselli, Elena, Onderzoeker, Zietek, Tamara, Onderzoeker, Stoddart, Gilly, Onderzoeker, Heusinkveld, Harm, Onderzoeker, Castell, Jose V, Onderzoeker, Benfenati, Emilio, Onderzoeker, Yang, Huan, Onderzoeker, Perera, Simón, Onderzoeker, Paini, Alicia, Onderzoeker, Kramer, Nynke, Onderzoeker, Hartung, Thomas, Onderzoeker, Janssen, Manoe, Onderzoeker, Fritsche, Ellen, Onderzoeker, Jennen, Danyel, Onderzoeker, Piumatti, Matteo, Onderzoeker, Rathman, James, Onderzoeker, Marusczyk, Jörg, Onderzoeker, Milec, Lucia, Onderzoeker, Roggen, Erwin, Onderzoeker

المساهمون: Innovative Testing in Life Sciences and Chemistry, Hogeschool Utrecht@@@Kenniscentrum Gezond en Duurzaam Leven

المصدر: Alternatives to Laboratory Animals. 52(2):117-131

مصطلحات موضوعية: new approach methodologies (NAMs), artificial intelligence, confidence, end-user acceptance, hackathon, next generation risk assessment, non-animal, probabilistic risk assessment, stakeholder network, toxicology

URL الوصول: https://surfsharekit.nl/public/24f20cf2-2901-48a9-a3e2-c1c57230ad4b

الاتاحة: http://www.hbo-kennisbank.nl/en/page/hborecord.view/?uploadId=sharekit_hu:oai:surfsharekit.nl:24f20cf2-2901-48a9-a3e2-c1c57230ad4b

المؤلفون: Brecklinghaus, Tim, Castell, José V., Hengstler, Jan G., Tolosa Pardo, Laia, Damm, Georg

المصدر: Brecklinghaus, Tim Castell, José V. Hengstler, Jan G. Tolosa Pardo, Laia Damm, Georg 2022 In vitro/in silico prediction of drug induced steatosis in relation to oral doses and blood concentrations by the Nile Red assay Toxicology Letters 368 33 46

مصطلحات موضوعية: bioquímica, bioquímica clínica

وصف الملف: application/pdf

Relation: Toxicology Letters, 2022, vol. 368, p. 33-46; https://hdl.handle.net/10550/98098; 159554

الاتاحة: https://hdl.handle.net/10550/98098
https://doi.org/10.1016/j.toxlet.2022.08.006

المؤلفون: López Riera, Mireia, Conde, Isabel, Quintás Soriano, Guillermo, Pedrola, Laia, Zaragoza, Angela, Pérez Rojas, Judith, Salcedo, Mario, Benlloch, Salvador, Castell, José V., Jover Atienza, Ramiro

المصدر: López Riera, Mireia Conde, Isabel Quintas, Guillermo Pedrola, Laia Zaragoza, Angela Pérez Rojas, Judith Salcedo, Mario Benlloch, Salvador Castell, José V. Jover Atienza, Ramiro 2018 Non-invasive prediction of NAFLD severity: a comprehensive, independent validation of previously postulated serum microRNA biomarkers Scientific Reports 8 1 10606-1 15

مصطلحات موضوعية: bioquímica, medicina

وصف الملف: application/pdf

Relation: Scientific Reports, 2018, vol. 8, num. 1, p. 10606-1-15; https://hdl.handle.net/10550/100335; 132335

الاتاحة: https://hdl.handle.net/10550/100335
https://doi.org/10.1038/s41598-018-28854-4

المؤلفون: Diemar, Michael G., Vinken, Mathieu, Teunis, Marc, Krul, Cyrille A.M., Busquet, Francois, Zajac, Julia Dominika, Kandarova, Helena, Corvi, Raffaella, Rosso, Matteo Z., Kharina, Anastasiia, Bryndum, Louise Stab, Santillo, Michael, Bloch, Denise, Kucheryavenko, Olena, Panagiotakos, Demosthenes, Rogiers, Vera, Beekhuijzen, Manon, Giusti, Arianna, Najjar, Abdulkarim, Courage, Carol, Koenig, Torben, Kolle, Susanne, Boonen, Harrie, Dhalluin, Stephane, Boberg, Julie, Müller, Boris P., Kukic, Predrag, Ritskes-Hoitinga, Merel, Grasselli, Elena, Zietek, Tamara, Stoddart, Gilly, Heusinkveld, Harm J., Castell, Jose V., Benfenati, Emilio, Yang, Huan, Perera, Simón, Paini, Alicia, Kramer, Nynke I., Hartung, Thomas, Janssen, Manoe, Fritsche, Ellen, Jennen, Danyel G.J., Piumatti, Matteo, Rathman, James, Marusczyk, Jörg, Milec, Lucia, Roggen, Erwin L.

المساهمون: IRAS OH Toxicology, Afd Pharmacology

مصطلحات موضوعية: artificial intelligence, confidence, end-user acceptance, hackathon, NAMs, new approach methodologies, next generation risk assessment, non-animal, probabilistic risk assessment, stakeholder network, toxicology, General Biochemistry,Genetics and Molecular Biology, Medical Laboratory Technology

وصف الملف: application/pdf

Relation: https://dspace.library.uu.nl/handle/1874/437833

الاتاحة: https://dspace.library.uu.nl/handle/1874/437833

المؤلفون: Diemar, Michael G., Vinken, Mathieu, Teunis, Marc, Krul, Cyrille A.M., Busquet, Francois, Zajac, Julia Dominika, Kandarova, Helena, Corvi, Raffaella, Rossi, Matteo Z., Kharina, Anastasiia, Bryndum, Louise Stab, Santillo, Michael, Bloch, Denise, Kucheryavenko, Olena, Panagiotakos, Demosthenes, Rogiers, Vera, Beekhuijzen, Manon, Giusti, Arianna, Najjar, Abdulkarim, Courage, Carol, Koenig, Torben, Kolle, Susanne, Boonen, Harrie, Dhalluin, Stephane, Boberg, Julie, Müller, Boris P., Kukic, Predrag, Ritskes-Hoitinga, Merel, Grasselli, Elena, Zietek, Tamara, Stoddart, Gilly, Heusinkveld, Harm J., Castell, Jose V., Benfenati, Emilio, Yang, Huan, Perera, Simón, Paini, Alicia, Kramer, Nynke I., Hartung, Thomas, Janssen, Manoe, Fritsche, Ellen, Jennen, Danyel G.J., Piumatti, Matteo, Rathman, James, Marusczyk, Jörg, Milec, Lucia, Roggen, Erwin L.

المصدر: Diemar , M G , Vinken , M , Teunis , M , Krul , C A M , Busquet , F , Zajac , J D , Kandarova , H , Corvi , R , Rossi , M Z , Kharina , A , Bryndum , L S , Santillo , M , Bloch , D , Kucheryavenko , O , Panagiotakos , D , Rogiers , V , Beekhuijzen , M , Giusti , A , Najjar , A , Courage , C , Koenig , T , Kolle , S , Boonen , H , Dhalluin ....

مصطلحات موضوعية: artificial intelligence, confidence, end-user acceptance, hackathon, NAMs, new approach methodologies, next generation risk assessment, non-animal, probabilistic risk assessment, stakeholder network, toxicology

Relation: https://cris.maastrichtuniversity.nl/en/publications/b7f77fc2-2e77-469c-86c2-f65fd427ed2e

الاتاحة: https://cris.maastrichtuniversity.nl/en/publications/b7f77fc2-2e77-469c-86c2-f65fd427ed2e
https://doi.org/10.1177/02611929231225730

المؤلفون: Ortega-Vallbona, Rita, Méndez, Rebeca, Tolosa, Laia, Escher, Sylvia E., Castell, José V., Gozalbes, Rafael, Serrano-Candelas, Eva

المساهمون: Horizon 2020, University of Valencia, CIBEREHD

المصدر: Toxicology ; volume 504, page 153764 ; ISSN 0300-483X

الاتاحة: http://dx.doi.org/10.1016/j.tox.2024.153764
https://api.elsevier.com/content/article/PII:S0300483X24000453?httpAccept=text/xml
https://api.elsevier.com/content/article/PII:S0300483X24000453?httpAccept=text/plain

المؤلفون: Martínez-Sena, Teresa, Moro,Erika, Moreno-Torres, Marta, Quintás, Guillermo, Hengstler, Jan, Castell, Jose V.

المصدر: http://lobid.org/resources/991000023569706485#!, 97(6):1723-1738.

مصطلحات موضوعية: HepG2 cell, mechanisms of hepatotoxicity, metabolomics, drug hepatotoxicity, in vitro

Relation: https://repository.publisso.de/resource/frl:6483371; https://doi.org/10.1007/s00204-023-03474-8; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182947/; https://link.springer.com/article/10.1007/s00204-023-03474-8#Sec17

الاتاحة: https://repository.publisso.de/resource/frl:6483371
https://doi.org/10.1007/s00204-023-03474-8
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182947/
https://link.springer.com/article/10.1007/s00204-023-03474-8#Sec17

المؤلفون: Garcia Llorens, Guillem, Lopez Navarro, Sergi, Jaijo, Teresa, Castell, José V., Bort Martí, Roque

مصطلحات موضوعية: Bioquímica, Biologia

وصف الملف: application/pdf

Relation: Journal Of Personalized Medicine, 2022, vol. 12, num. 7, p. 1-11; Garcia Llorens, Guillem Lopez Navarro, Sergi Jaijo, Teresa Castell Ripoll, José Vicente Bort Martí, Roque 2022 Modeling a Novel Variant of Glycogenosis IXa Using a Clonal Inducible Reprogramming System to Generate "Diseased" Hepatocytes for Accurate Diagnosis. Journal Of Personalized Medicine 12 7 1 11; https://hdl.handle.net/10550/87188; 159555

الاتاحة: https://hdl.handle.net/10550/87188
https://doi.org/10.3390/jpm12071111

المؤلفون: Rodríguez Agudo, Rubén, Petrov, Petar D., Castell, José V., over Atienza, Ramiro

مصطلحات موضوعية: Bioquímica clínica

وصف الملف: application/pdf

Relation: Antioxidants, 2022, vol. 11, num. 5, p. 897; Rodríguez Agudo, Rubén Petrov, Petar D. Castell, José V. over Atienza, Ramiro 2022 Methionine cycle rewiring by targeting miR-873-5p modulates ammonia metabolism to protect the liver from acetaminophen Antioxidants 11 5 897; https://hdl.handle.net/10550/87070; 159246

الاتاحة: https://hdl.handle.net/10550/87070
https://doi.org/10.3390/antiox11050897

المؤلفون: Moreno Torres, Marta, Quintás Soriano, Guillermo, Castell, José V.

مصطلحات موضوعية: Bioquímica, Biologia

وصف الملف: application/pdf

Relation: Metabolites, 2022, vol. 12, num. 6, p. 564-582; Moreno Torres, Marta Quintás Soriano, Guillermo Castell, José V. 2022 The Potential Role of Metabolomics in Drug-Induced Liver Injury (DILI) Assessment Metabolites 12 6 564 582; https://hdl.handle.net/10550/86693; 158851

الاتاحة: https://hdl.handle.net/10550/86693
https://doi.org/10.3390/metabo12060564

المؤلفون: Quintás Soriano, Guillermo, Castell, José V., Moreno Torres, Marta

مصطلحات موضوعية: Bioquímica, Biologia

وصف الملف: application/pdf

Relation: Frontiers In Pharmacology, 2023, vol. 14, p. 1-22; Quintás Soriano, Guillermo Castell, José V. Moreno Torres, Marta 2023 The assessment of the potential hepatotoxicity of new drugs by in vitro metabolomics Frontiers In Pharmacology 14 1 22; https://hdl.handle.net/10550/86669; 158845

الاتاحة: https://hdl.handle.net/10550/86669
https://doi.org/10.3389/fphar.2023.1155271

المؤلفون: Moreno Torres, Marta, Ten Doménech, Isabel, Martínez-Sena, Teresa, Sanjuan Herráez, Juan Daniel, Castell, José V., Parra Llorca, Anna, Vento Torres, Máximo, Quintás Soriano, Guillermo, Kuligowski, Julia

مصطلحات موضوعية: Bioquímica, Biologia

وصف الملف: application/pdf

Relation: Metabolites, 2020, vol. 10, num. 4, p. 126-136; Moreno Torres, Marta Ten Doménech, Isabel Martínez-Sena, Teresa Sanjuan Herráez, Juan Daniel Castell, José V. Parra Llorca, Anna Vento Torres, Máximo Quintás Soriano, Guillermo Kuligowski, Julia 2020 Comparing Targeted vs. Untargeted MS2 Data-Dependent Acquisition for Peak Annotation in LC-MS Metabolomics Metabolites 10 4 126 136; https://hdl.handle.net/10550/86714; 159095

الاتاحة: https://hdl.handle.net/10550/86714
https://doi.org/10.3390/metabo10040126

المؤلفون: Moreno Torres, Marta, Garcia Llorens, Guillem, Moro, Erika, Méndez, Rebeca, Quintás Soriano, Guillermo, Castell, José V.

مصطلحات موضوعية: Productes químics

وصف الملف: application/pdf

Relation: Scientific Reports, 2021, vol. 11, num. 1, p. 22119; Moreno Torres, Marta Garcia Llorens, Guillem Moro, Erika Méndez, Rebeca Quintás Soriano, Guillermo Castell, José V. 2021 Factors that influence the quality of metabolomics data in in vitro cell toxicity studies: a systematic survey Scientific Reports 11 1 22119; https://hdl.handle.net/10550/87598; 153854

الاتاحة: https://hdl.handle.net/10550/87598
https://doi.org/10.1038/s41598-021-01652-1

المؤلفون: Garcia Llorens, Guillem, Martínez Sena, Teresa, Pareja Ibars, Eugenia, Tolosa Pardo, Laia, Castell, José V., Bort Martí, Roque

مصطلحات موضوعية: Química farmacèutica

وصف الملف: application/pdf

Relation: Stem Cell Research & Therapy, 2023, vol. 14, num. 1, p. 94; Garcia Llorens, Guillem Martínez Sena, Teresa Pareja Ibars, Eugenia Tolosa Pardo, Laia Castell, José V. Bort Martí, Roque 2023 A robust reprogramming strategy for generating hepatocyte-like cells usable in pharmaco-toxicological studies. Stem Cell Research & Therapy 14 1 94; https://hdl.handle.net/10550/87131; 159552

الاتاحة: https://hdl.handle.net/10550/87131
https://doi.org/10.1186/s13287-023-03311-w

المؤلفون: IRAS OH Toxicology, Afd Pharmacology, IRAS – One Health Toxicology, Diemar, Michael G., Vinken, Mathieu, Teunis, Marc, Krul, Cyrille A.M., Busquet, Francois, Zajac, Julia Dominika, Kandarova, Helena, Corvi, Raffaella, Rosso, Matteo Z., Kharina, Anastasiia, Bryndum, Louise Stab, Santillo, Michael, Bloch, Denise, Kucheryavenko, Olena, Panagiotakos, Demosthenes, Rogiers, Vera, Beekhuijzen, Manon, Giusti, Arianna, Najjar, Abdulkarim, Courage, Carol, Koenig, Torben, Kolle, Susanne, Boonen, Harrie, Dhalluin, Stephane, Boberg, Julie, Müller, Boris P., Kukic, Predrag, Ritskes-Hoitinga, Merel, Grasselli, Elena, Zietek, Tamara, Stoddart, Gilly, Heusinkveld, Harm J., Castell, Jose V., Benfenati, Emilio, Yang, Huan, Perera, Simón, Paini, Alicia, Kramer, Nynke I., Hartung, Thomas, Janssen, Manoe, Fritsche, Ellen, Jennen, Danyel G.J., Piumatti, Matteo, Rathman, James, Marusczyk, Jörg, Milec, Lucia, Roggen, Erwin L.

URL: https://doi.org/10.1177/02611929231225730
http://hdl.handle.net/1874/437833
https://dspace.library.uu.nl/handle/1874/437833
http://www.scopus.com/inward/record.url?scp=85182697833&partnerID=8YFLogxK
0261-1929
Alternatives to Laboratory Animals
52
2
117
131

المؤلفون: Castell, José V., Verheijen, Marcha, Sarkans, Ugis, Jennen, Danyel, Caiment, Florian, Kleinjans, Jos, Wolski, Witold

المصدر: Castell Ripoll, José Vicente Verheijen, Marcha Sarkans, Ugis Jennen, Danyel Caiment, Florian Kleinjans, Jos Wolski, Witold 2022 Multi-omics HeCaToS dataset of repeated dose toxicity for cardiotoxic & hepatotoxic compounds. Scientific Data 9 699 1 11

مصطلحات موضوعية: Bioquímica, Biologia

Relation: Scientific Data, 2022, vol. 9, num. 699, p. 1-11; https://hdl.handle.net/10550/87180; https://doi.org/10.1038/s41597-022-01825-1; 159553

الاتاحة: https://hdl.handle.net/10550/87180
https://doi.org/10.1038/s41597-022-01825-1

المؤلفون: Santamaria, Ramon, Ballester, Maria, Garcia-Llorens, Guillem, Martinez, Francisco, Blazquez, Marina, Ribes-Koninckx, Carmen, Castell, Jose V., Wuestefeld, Torsten, Bort, Roque

المساهمون: School of Biological Sciences, Genome Institute of Singapore, A*STAR, National Cancer Centre, Singapore, SingHealth

مصطلحات موضوعية: Science::Biological sciences, Biological Therapy, Fibroblast

وصف الملف: application/pdf

Relation: Scientific Reports; Santamaria, R., Ballester, M., Garcia-Llorens, G., Martinez, F., Blazquez, M., Ribes-Koninckx, C., Castell, J. V., Wuestefeld, T. & Bort, R. (2022). Derivation of healthy hepatocyte-like cells from a female patient with ornithine transcarbamylase deficiency through X-inactivation selection. Scientific Reports, 12(1), 2308-. https://dx.doi.org/10.1038/s41598-022-06184-w; https://hdl.handle.net/10356/163355; 2-s2.0-85124446539; 12; 2308

الاتاحة: https://hdl.handle.net/10356/163355
https://doi.org/10.1038/s41598-022-06184-w

المؤلفون: Moreno-Torres, Marta, Kumar, Manoj, García-Llorens, Guillem, Quintás, Guillermo, Tricot, Tine, Boon, Ruben, Tolosa, Laia, Toprakhisar, Burak, Chesnais, Francois, Verfaillie, Catherine, Castell, José V.

المصدر: Moreno-Torres , M , Kumar , M , García-Llorens , G , Quintás , G , Tricot , T , Boon , R , Tolosa , L , Toprakhisar , B , Chesnais , F , Verfaillie , C & Castell , J V 2022 , ' A Novel UPLC-MS Metabolomic Analysis-Based Strategy to Monitor the Course and Extent of iPSC Differentiation to Hepatocytes ' , JOURNAL OF PROTEOME RESEARCH , vol. 21 , no. 3 , pp. 702-712 . https://doi.org/10.1021/acs.jproteome.1c00779

مصطلحات موضوعية: General Chemistry, Biochemistry

الاتاحة: https://kclpure.kcl.ac.uk/portal/en/publications/a9d7451e-cddc-4cbd-93a0-661a3038882d
https://doi.org/10.1021/acs.jproteome.1c00779
http://www.scopus.com/inward/record.url?scp=85122668211&partnerID=8YFLogxK

المؤلفون: Brecklinghaus, Tim, Albrecht, Wiebke, Duda, Julia, Kappenberg, Franziska, Gruendler, Lisa, Edlund, Karolina, Marchan, Rosemarie, Ghallab, Ahmed, Cadenas, Cristina, Rieck, Adrian, Vartak, Nachiket, Tolosa, Laia, Castell, Jose, V, Gardner, Iain, Halilbasic, Emina, Trauner, Michael, Ullrich, Anett, Zeigerer, Anja, Turgunbayer, Oezlem Demirci, Damm, Georg

المصدر: TOXICOLOGY LETTERS 368 33-46

Relation: https://aperta.ulakbim.gov.tr/record/253943; oai:aperta.ulakbim.gov.tr:253943

الاتاحة: https://aperta.ulakbim.gov.tr/record/253943

المؤلفون: Taléns Visconti, Raquel, Bonora Centelles, A., Castell, José V., Gómez Lechón-Molinero, Maria Jose.

المصدر: Talens Visconti, Raquel Bonora Centelles, A. Castell, Jose V. Gómez Lechón-Molinero, Maria Jose. 2006 Alternative sources of hepatocytes for cell therapy Gastroenterologia y Hepatologia 29 6 366 376

مصطلحات موضوعية: medicina, UNESCO::QUÍMICA

وصف الملف: application/pdf

Relation: Gastroenterologia y Hepatologia, 2006, vol. 29, num. 6, p. 366-376; Taléns-Visconti, R., Bonora-Centelles, A., Vicente Castell, J., & José Gómez-Lechón, M. (2006). Fuentes alternativas de hepatocitos para la terapia celular. En Gastroenterología y Hepatología (Vol. 29, Issue 6, pp. 366-376). Elsevier BV. https://doi.org/10.1157/13089719; https://hdl.handle.net/10550/93143; 073312

الاتاحة: https://hdl.handle.net/10550/93143
https://doi.org/10.1157/13089719